Implications of central immune signaling caused by drugs of abuse: Mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence

Pharmacology and Therapeutics

Volumn 134, Issue 2, 2012, Pages 219-245

  Coller, Janet K ^a   Hutchinson, Mark R ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Astrocyte; Chemokine; Cytokine; Drug addiction; Microglia; Toll like receptor

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ACETALDEHYDE; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; COCAINE; DRUGS USED IN THE TREATMENT OF ADDICTION; FIBROBLAST GROWTH FACTOR 1; GAMMA INTERFERON; IBUDILAST; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; METHAMPHETAMINE; MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MONOCYTE CHEMOTACTIC PROTEIN 1; MORPHINE; NALOXONE; OPIATE; PROPENTOFYLLINE; PTI 609; RANTES; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALCOHOLISM; BEHAVIOR; COCAINE DEPENDENCE; CYTOKINE PRODUCTION; DRUG DEPENDENCE; ECSTASY ADDICTION; GENE EXPRESSION; GLIA; HUMAN; IMMUNOGENETICS; IMMUNOMODULATION; IN VIVO STUDY; INNATE IMMUNITY; LOCOMOTION; METHAMPHETAMINE ADDICTION; MICROGLIA; MORPHINE ADDICTION; MOTOR DYSFUNCTION; NERVE CONDUCTION; NEUROIMMUNOLOGY; NEUROTRANSMISSION; NONHUMAN; OPIATE ADDICTION; PREDICTION; PRIORITY JOURNAL; REVIEW; SEDATION; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; WITHDRAWAL SYNDROME;

ANIMALS; CENTRAL NERVOUS SYSTEM; HUMANS; IMMUNE SYSTEM; NEUROIMMUNOMODULATION; SIGNAL TRANSDUCTION; SUBSTANCE-RELATED DISORDERS;

EID: 84859164991     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2012.01.008     Document Type: Review

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