Minocycline reduces the injury-induced expression of prodynorphin and pronociceptin in the dorsal root ganglion in a rat model of neuropathic pain

Neuroscience

Volumn 165, Issue 4, 2010, Pages 1420-1428

  Mika, J ^a   Rojewska, E ^a   Makuch, W ^a   Przewlocka, B ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

glia; minocycline; neuropathic pain; prodynorphin; proenkephalin; pronociceptin

Indexed keywords

COMPLEMENT COMPONENT C1Q; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; MINOCYCLINE; NEUROPEPTIDE; NOCICEPTIN; PRODYNORPHIN; PROENKEPHALIN; PRONOCICEPTIN; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL TRANSPORT; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; GLIA CELL; IMMUNOCOMPETENT CELL; INHIBITION KINETICS; LUMBAR SPINAL CORD; MACROPHAGE ACTIVATION; MALE; MICROGLIA; NERVE INJURY; NEUROPATHIC PAIN; NEUTROPHIL CHEMOTAXIS; NOCICEPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SATELLITE CELL; SCIATIC NERVE; SPINAL GANGLION; UPREGULATION;

ANIMALS; CENTRAL NERVOUS SYSTEM AGENTS; DISEASE MODELS, ANIMAL; ENKEPHALINS; GANGLIA, SPINAL; LUMBAR VERTEBRAE; MALE; MINOCYCLINE; NEUROIMMUNOMODULATION; PAIN; PROTEIN PRECURSORS; RATS; RATS, WISTAR; RECEPTORS, OPIOID; RNA, MESSENGER; SCIATIC NEUROPATHY; SPINAL CORD;

EID: 73649211066     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.11.064     Document Type: Article

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