Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia

Brain, Behavior, and Immunity

Volumn 22, Issue 8, 2008, Pages 1178-1189

  Hutchinson, Mark R ^a,b   Coats, Benjamen D ^a   Lewis, Susannah S ^a   Zhang, Yingning ^a   Sprunger, David B ^a   Rezvani, Niloofar ^a   Baker, Eric M ^a   Jekich, Brian M ^a   Wieseler, Julie L ^a   Somogyi, Andrew A ^b   Martin, David ^c   Poole, Stephen ^d   Judd, Charles M ^a   Maier, Steven F ^a   Watkins, Linda R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c AMGEN INC   (United States)

^d NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

Chemokine; Glia; Microglia; Morphine; Nitric oxide; p38 MAP kinase; Proinflammatory cytokine; Tolerance; Toll like receptor 4

Indexed keywords

ANALGESIC AGENT; CHEMOKINE; CHEMOKINE RECEPTOR CX3CR1; CYTOKINE; FRACTALKINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MESSENGER RNA; METHADONE; MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; MORPHINE SULFATE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; OPIATE; RANTES; SB 203508; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CELL ACTIVATION; CELL FUNCTION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DORSAL ROOT; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERANCE; GLIA CELL; HYPERALGESIA; INFLAMMATION; LONG TERM CARE; LUMBAR SPINAL CORD; MALE; MONOTHERAPY; NERVE CELL; NOCICEPTION; NONHUMAN; PAIN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; SPINAL CORD NERVE CELL;

ANALGESIA; ANALGESICS, OPIOID; ANIMALS; CATHETERS, INDWELLING; CHEMOKINE CX3CL1; CYTOKINES; HYPERALGESIA; INJECTIONS, SPINAL; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; MALE; METHADONE; MORPHINE; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPINAL CORD; TIME FACTORS;

EID: 52949150075     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2008.05.004     Document Type: Article

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