Glial cell loss in the hippocampus of alcoholics

Alcoholism: Clinical and Experimental Research

Volumn 23, Issue 1, 1999, Pages 164-168

  Korbo, Lise ^a,b  

^a Kommunehospitalet ^*  (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Alcohol; Astrocytes; Dementia; Fractionator; Stereology

Indexed keywords

ADULT; ALCOHOL ABUSE; ALCOHOLISM; ARTICLE; ASTROCYTE; BRAIN TISSUE; CELL LOSS; CLINICAL ARTICLE; COGNITIVE DEFECT; DEMENTIA; GLIA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LEARNING; MALE; MEMORY; NEUROPATHOLOGY; NEUROPSYCHOLOGY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STEREOLOGY; WERNICKE KORSAKOFF SYNDROME;

EID: 0032928384     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1999.tb04039.x     Document Type: Article

References (42)

1. Lee K, Møller L, Hardt F, Haubek A, Jensen E: Alcohol-induced brain damage and liver damage in young males. Lancet ii:759-761, 1979
2. Carlen PL, Wilkinson A, Wortzman G, Holgate R, Cordingley J, Lee MA, Huszar L, Moddel G, Singh R, Kiraly L, Rankin JG: Cerebral atrophy and functional deficits in alcoholics without clinically apparent liver disease. Neurology 31:377-385, 1981
3. Carlen PL, Wilkinson DA: Reversibility of alcohol-related brain damage: Clinical and experimental observations. Acta Med Scand 717(Suppl.):19-26, 1987
4. Charness ME, Simon RP, Greenberg DA: Ethanol and the nervous system. N Engl J Med 321:442-454, 1989
5. Harper CG, Kril JJ, Holloway RL: Brain shrinkage in chronic alcoholics: A pathological study. Br Med J 290:501-504, 1985
6. de la Monte S: Disproportionate atrophy of cerebral white matter in chronic alcoholics. Arch Neurol 45:990-992, 1988
7. Harper CG, Kril JJ: Neuropathology of alcoholism. Alcohol Alcohol 25:207-216, 1990
8. Lishman WA: Alcohol and the brain. Br J Psychiatry 156:635-644, 1990
9. Charness ME: Brain lesions in alcoholics. Alcohol Clin Exp Res 17:2-11, 1993
10. Jernigan TL, Schafer K, Butters N, Cermak LS: Magnetic resonance imaging of alcoholic Korsakoff patients. Neuropsychopharmacology 4:175-186, 1991
11. Lishman WA, Jacobson RR, Acker C: Brain damage in alcoholism: Current concepts. Acta Med Scand 717(Suppl.):5-17, 1987
12. Victor M, Adams RD, Collins GH: The Wernicke-Korsakoff Syndrome and Related Neurologic Disorders Due to Alcoholism and Malnutrition, ed 2. Philadelphia, F. A. Davis Company, 1989
13. Harper C, Kril J, Daly J: Are we drinking our neurones away? Br Med J 294:534-536, 1987
14. Jensen GB, Pakkenberg B: Do alcoholics drink their neurons away? Lancet 342:1201-1204, 1993
15. Walker DW, Barnes DE, Zornetzer SF, Hunter BE, Kubanis P: Neuronal loss in hippocampus induced by prolonged ethanol consumption in rats. Science 209:711-713, 1980
16. Paula-Barbosa MM, Brandao F, Madeira MD, Cadete-Leite A: Structural changes in the hippocampal formation after long-term alcohol consumption and withdrawal in the rat. Addiction 88:237-247, 1993
17. Eichenbaum H, Otto T, Cohen NJ: The hippocampus - What does it do. Behav Neural Biol 57:2-36, 1992
18. West MJ, Coleman PD, Flood DG, Troncoso JC: Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 344:769-772, 1994
19. Norenberg MD: Astrocyte response to CNS injury. J Neuropathol Exp Neurol 53:213-220, 1994
20. West MJ, Gundersen HJG: Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol 296:1-22, 1990
21. Amaral DG, Insausti R: Hippocampal formation, in Paxinox G (ed): The Human Nervous System. New York, Academic Press, Inc., 1990, p 711
22. Gundersen HJG: Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. J Microsc 143:3-45, 1986
23. Gundersen HJG, Bagger P, Bendtsen TF, Evans SM, Korbo L, Marcussen N, Møller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sørensen FB, Vesterby A, West MJ: The new stereological tools: Disector, fractionator, selector, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 96:857-881, 1988
24. West MJ, Slomianka L, Gundersen HJG: Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat Rec 231:482-497, 1991
25. Korbo L, Ladefoged O, Lam HR, Østergaard G, West MJ, Arlien-Søborg P: Neuronal loss in hippocampus in rats exposed to toluene. Neurotoxicology 17:359-366, 1996
26. Sterio DC: The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 134:127-136, 1984
27. Gundersen HJG: Notes on the estimation of the numerical density of arbitrary profiles: The edge effect. J Microsc 111:219-223, 1977
28. Duchen LW: General pathology of neurons and neuroglia, in Adams JH, Corsellis JAN, Duchen LW (eds): Greenfield's Neuropathology, ed 4. London, Edward Arnold, 1984, pp 1-52
29. Gundersen HJG, Jensen EB: The efficiency of systematic sampling in stereology and its prediction. J Microsc 147:229-263, 1987
30. Pakkenberg B: Pronounced reduction of total neuron number in mediodorsal thalamic nucleus and nucleus accumbens in schizophrenics. Arch Gen Psychiatry 47:1023-1028, 1990
31. Kril JJ, Halliday GM, Svoboda MD, Cartwright H: The cerebral cortex is damaged in chronic alcoholics. Neuroscience 79:983-998, 1997
32. Cadete-Leite A, Tavares MA, Pacheco MM, Volk B, Paula-Barbosa MM: Hippocampal mossy fiber-CA3 synapses after chronic alcohol consumption and withdrawal. Alcohol 6:303-310, 1989
33. Paula-Barbosa MM, Brandao F, Andrade JP, Madeira MD, Zimmer J, Cadete-Leite A: Intracerebral grafting impedes hippocampal cell loss during withdrawal after long-term alcohol consumption in rats. Alcohol Alcohol 26:177-190, 1991
34. Bengoechea O, Gonzalo LM: Effects of alcoholization on the rat hippocampus. Neurosci Lett 123:112-114, 1991
35. McMullen PA, Saint-Cyr JA, Carlen PL: Morphological alterations in rat CA1 hippocampal pyramidal cell dendrites resulting from chronic ethanol consumption and withdrawal. J Comp Neurol 225:111-118, 1984
36. Harper C, Corbett D: Changes in the basal dendrites of cortical pyramidal cells from alcoholic patients - A quantitative Golgi study. J Neurol Neurosurg Psychiatry 53:856-861, 1990
37. Kjellström C, Almström S, Conradi N: Decreased synapse-to-neuron ratio in rat locus ceruleus following chronic ethanol feeding. Alcohol Clin Exp Res 17:406-410, 1993
38. Reed RJ, Grant I, Rourke SB: Long-term abstinent alcoholics have normal memory. Alcohol Clin Exp Res 16:677-683, 1992
39. Giaume C, McCarthy KD: Control of gap-junctional communication in astrocytic networks. Trends Neurosci 19:319-325, 1996
40. Steinhäuser C, Gallo V: News on glutamate receptors in glial cells. Trends Neurosci 19:339-345, 1996
41. Doyle RT, Araque A, Haydon PG: Astrocytes enhance synapse formation between cultured rat hippocampal neurons. Soc Neurosci 22: 766.6, 1996 (abstr)
42. Montoliu C, Sancho-Tello M, Azorin I, Burgal M, Vallés S, Renau-Piqueras J, Guerri C: Ethanol increases cytochrome P4502E1 and induces oxidative stress in astrocytes. J Neurochem 65:2561-2570, 1995