Methamphetamine-induced neurotoxicity in mouse brain is attenuated by ketoprofen, a non-steroidal anti-inflammatory drug

Neuroscience Letters

Volumn 352, Issue 1, 2003, Pages 13-16

  Asanuma, Masato ^a   Tsuji, Takeshi ^a   Miyazaki, Ikuko ^a   Miyoshi, Ko ^a   Ogawa, Norio ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Aspirin; Ketoprofen; Methamphetamine; Microglia; Neurotoxicity; Non steroidal anti inflammatory drug

Indexed keywords

ACETYLSALICYLIC ACID; DOPAMINE TRANSPORTER; KETOPROFEN; METHAMPHETAMINE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TOXICITY; CELL ACTIVATION; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; INFLAMMATION; INHIBITION KINETICS; MALE; MICROGLIA; MOUSE; MOUSE STRAIN; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

EID: 0242459201     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2003.08.015     Document Type: Article

References (17)

1. Aeberhard E.E., Henderson S.A., Arabolos N.S., Griscavage J.M., Castro F.E., Barrett C.T., Ignarro L.J. Non-steroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene. Biochem. Biophys. Res. Commun. 208:1995;1053-1059.
2. Asanuma M., Cadet J.L. Methamphetamine-induced increase in striatal NF-κB DNA-binding activity is attenuated in superoxide dismutase transgenic mice. Mol. Brain Res. 60:1998;305-309.
3. Asanuma M., Hirata H., Cadet J.L. Attenuation of 6-hydroxydopamine- induced dopaminergic nigrostriatal lesions in superoxide dismutase transgenic mice. Neuroscience. 85:1998;907-917.
4. Asanuma M., Miyazaki I., Higashi Y., Cadet J.L., Ogawa N. Methamphetamine-induced increase in striatal p53 DNA-binding activity is attenuated in Cu,Zn-superoxide dismutase transgenic mice. Neurosci. Lett. 325:2002;191-194.
5. Asanuma M., Nishibayashi-Asanuma S., Miyazaki I., Kohno M., Ogawa N. Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals. J. Neurochem. 76:2001;1895-1904.
6. Cadet J.L., Brannock C. Free radicals and the pathobiology of brain dopamine systems. Neurochem. Int. 32:1998;117-131.
7. Cadet J.L., Sheng P., Ali S., Rothman R., Carlson E., Epstein C.J. Attenuation of methamphetamine-induced neurotoxicity in copper/zinc superoxide dismutase transgenic mice. J. Neurochem. 62:1994;380-383.
8. Du Z.Y., Li X.Y. Inhibitory effects of indomethacin on interleukin-1 and nitric oxide production in rat microglia in vitro. Int. J. Immunopharmacol. 21:1999;219-225.
9. Hirata H., Cadet J.L. p53-knockout mice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies. J. Neurochem. 69:1997;780-790.
10. Hirata H., Ladenheim B., Carlson E., Epstein C., Cadet J.L. Autoradiographic evidence for methamphetamine induced striatal dopaminergic loss in mouse brain: attenuation in CuZn-superoxide dismutase transgenic mice. Brain Res. 714:1996;95-103.
11. Imam S.Z., Newport G.D., Itzhak Y., Cadet J.L., Islam F., Slikker W.J., Ali S.F. Peroxynitrite plays a role in methamphetamine-induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper-zinc superoxide dismutase. J. Neurochem. 76:2001;745-749.
12. Itzhak Y., Ali S.F. The neuronal nitric oxide synthase inhibitor, 7-nitroindazole, protects against methamphetamine-induced neurotoxicity in vivo. J. Neurochem. 67:1996;1770-1773.
13. Kita T., Shimada K., Mastunari Y., Wagner G.C., Kubo K., Nakashima T. Methamphetamine-induced striatal dopamine neurotoxicity and cyclooxygenase-2 protein expression in BALB/c mice. Neuropharmacology. 39:2000;399-406.
14. Ladenheim B., Krasnova I.N., Deng X., Oyler J.M., Polettini A., Moran T.H., Huestis M.A., Cadet J.L. Methamphetamine-induced neurotoxicity is attenuated in transgenic mice with a null mutation for interleukin-6. Mol. Pharmacol. 58:2000;1247-1256.
15. O'Neill L.A.J., Kaltschmidt C. NF-κB: a crucial transcription factor for glial and neuronal cell function. Trends Neurosci. 20:1997;252-258.
16. Wu H., Lozano G. NF-κB activation of p53: a potential mechanism for suppressing cell growth in response to stress. J. Biol. Chem. 269:1994;20067-20074.
17. Yamaguchi T., Kuraishi Y., Minami M., Nakai S., Hirai Y., Satoh M. Methamphetamine-induced expression of interleukin-1β mRNA in the rat hypothalamus. Neurosci. Lett. 128:1991;90-92.