Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment

Brain, Behavior, and Immunity

Volumn 25, Issue SUPPL. 1, 2011, Pages

  Wu, Yue ^a   Lousberg, Erin L ^b,c   Moldenhauer, Lachlan M ^a   Hayball, John D ^a,b,c   Robertson, Sarah A ^a   Coller, Janet K ^a   Watkins, Linda R ^d   Somogyi, Andrew A ^a   Hutchinson, Mark R ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b HANSON INSTITUTE   (Australia)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Alcohol; Cytokine; Interleukin 1 ; Microglia; Minocycline; Motor impairment; Sedation

Indexed keywords

ALCOHOL; I KAPPA B ALPHA; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; HIPPOCAMPUS; MALE; MICROGLIA; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RIGHTING REFLEX; ROTAROD TEST; SEDATION; SIGNAL TRANSDUCTION; SLEEP TIME; SPLEEN CELL;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; HIPPOCAMPUS; INTERLEUKIN-1; MALE; MICE; MICE, INBRED BALB C; MICROGLIA; MINOCYCLINE; MOTOR ACTIVITY; NEURONS; PHOSPHORYLATION; RECEPTORS, INTERLEUKIN-1 TYPE I; REFLEX, RIGHTING; ROTAROD PERFORMANCE TEST; SIGNAL TRANSDUCTION; SLEEP;

EID: 79955717549     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2011.01.012     Document Type: Article

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