-
1
-
-
82755189243
-
TOX is required for development of the CD4 T cell lineage gene program
-
Aliahmad, P., Kadavallore, A., et al. TOX is required for development of the CD4 T cell lineage gene program. J. Immunol. 187:11 (2011), 5931–5940.
-
(2011)
J. Immunol.
, vol.187
, Issue.11
, pp. 5931-5940
-
-
Aliahmad, P.1
Kadavallore, A.2
-
2
-
-
2442561611
-
Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration
-
Allende, M.L., Dreier, J.L., et al. Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration. J. Biol. Chem. 279:15 (2004), 15396–15401.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.15
, pp. 15396-15401
-
-
Allende, M.L.1
Dreier, J.L.2
-
3
-
-
70349556314
-
Thymic epithelial cells: the multi-tasking framework of the T cell “cradle”
-
Alves, N.L., Huntington, N.D., et al. Thymic epithelial cells: the multi-tasking framework of the T cell “cradle”. Trends Immunol. 30:10 (2009), 468–474.
-
(2009)
Trends Immunol.
, vol.30
, Issue.10
, pp. 468-474
-
-
Alves, N.L.1
Huntington, N.D.2
-
4
-
-
40749125759
-
FOXN1 homozygous mutation associated with anencephaly and severe neural tube defect in human athymic Nude/SCID fetus
-
Amorosi, S., D'Armiento, M., et al. FOXN1 homozygous mutation associated with anencephaly and severe neural tube defect in human athymic Nude/SCID fetus. Clin. Genet. 73:4 (2008), 380–384.
-
(2008)
Clin. Genet.
, vol.73
, Issue.4
, pp. 380-384
-
-
Amorosi, S.1
D'Armiento, M.2
-
5
-
-
16244393745
-
Tbx1 is a transcriptional activator involved in head and pharyngeal arch development in Xenopus laevis
-
Ataliotis, P., Ivins, S., et al. Tbx1 is a transcriptional activator involved in head and pharyngeal arch development in Xenopus laevis. Dev. Dyn. 232:4 (2005), 979–991.
-
(2005)
Dev. Dyn.
, vol.232
, Issue.4
, pp. 979-991
-
-
Ataliotis, P.1
Ivins, S.2
-
6
-
-
67649647895
-
Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates
-
Bajoghli, B., Aghaallaei, N., et al. Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates. Cell 138:1 (2009), 186–197.
-
(2009)
Cell
, vol.138
, Issue.1
, pp. 186-197
-
-
Bajoghli, B.1
Aghaallaei, N.2
-
7
-
-
0036852151
-
Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice
-
Balciunaite, G., Keller, M.P., et al. Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice. Nat. Immunol. 3:11 (2002), 1102–1108.
-
(2002)
Nat. Immunol.
, vol.3
, Issue.11
, pp. 1102-1108
-
-
Balciunaite, G.1
Keller, M.P.2
-
8
-
-
2442656306
-
DiGeorge syndrome: an update
-
Baldini, A., DiGeorge syndrome: an update. Curr. Opin. Cardiol. 19:3 (2004), 201–204.
-
(2004)
Curr. Opin. Cardiol.
, vol.19
, Issue.3
, pp. 201-204
-
-
Baldini, A.1
-
9
-
-
42049087865
-
The earliest thymic progenitors for T cells possess myeloid lineage potential
-
Bell, J.J., Bhandoola, A., The earliest thymic progenitors for T cells possess myeloid lineage potential. Nature 452:7188 (2008), 764–767.
-
(2008)
Nature
, vol.452
, Issue.7188
, pp. 764-767
-
-
Bell, J.J.1
Bhandoola, A.2
-
10
-
-
3242784226
-
Critical functions for c-Myb at three checkpoints during thymocyte development
-
Bender, T.P., Kremer, C.S., et al. Critical functions for c-Myb at three checkpoints during thymocyte development. Nat. Immunol. 5:7 (2004), 721–729.
-
(2004)
Nat. Immunol.
, vol.5
, Issue.7
, pp. 721-729
-
-
Bender, T.P.1
Kremer, C.S.2
-
11
-
-
49449098431
-
CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis
-
Bertrand, J.Y., Kim, A.D., et al. CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis. Development 135:10 (2008), 1853–1862.
-
(2008)
Development
, vol.135
, Issue.10
, pp. 1853-1862
-
-
Bertrand, J.Y.1
Kim, A.D.2
-
12
-
-
0029999218
-
The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors
-
Blackburn, C.C., Augustine, C.L., et al. The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors. Proc. Natl. Acad. Sci. USA 93:12 (1996), 5742–5746.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, Issue.12
, pp. 5742-5746
-
-
Blackburn, C.C.1
Augustine, C.L.2
-
13
-
-
0034536820
-
Chemokines define distinct microenvironments in the developing thymus
-
Bleul, C.C., Boehm, T., Chemokines define distinct microenvironments in the developing thymus. Eur. J. Immunol. 30:12 (2000), 3371–3379.
-
(2000)
Eur. J. Immunol.
, vol.30
, Issue.12
, pp. 3371-3379
-
-
Bleul, C.C.1
Boehm, T.2
-
14
-
-
0034844763
-
Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product
-
Bleul, C.C., Boehm, T., Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product. Eur. J. Immunol. 31:8 (2001), 2497–2503.
-
(2001)
Eur. J. Immunol.
, vol.31
, Issue.8
, pp. 2497-2503
-
-
Bleul, C.C.1
Boehm, T.2
-
15
-
-
26844543561
-
BMP signaling is required for normal thymus development
-
Bleul, C.C., Boehm, T., BMP signaling is required for normal thymus development. J. Immunol. 175:8 (2005), 5213–5221.
-
(2005)
J. Immunol.
, vol.175
, Issue.8
, pp. 5213-5221
-
-
Bleul, C.C.1
Boehm, T.2
-
16
-
-
78649873076
-
Hedgehog signalling in T-cell development: a non-redundant role for Gli1
-
Bommhardt, U., Hedgehog signalling in T-cell development: a non-redundant role for Gli1. Cell Cycle, 9(22), 2010, 4428.
-
(2010)
Cell Cycle
, vol.9
, Issue.22
, pp. 4428
-
-
Bommhardt, U.1
-
17
-
-
79952263403
-
HEB-deficient T-cell precursors lose T-cell potential and adopt an alternative pathway of differentiation
-
Braunstein, M., Anderson, M.K., HEB-deficient T-cell precursors lose T-cell potential and adopt an alternative pathway of differentiation. Mol. Cell. Biol. 31:5 (2011), 971–982.
-
(2011)
Mol. Cell. Biol.
, vol.31
, Issue.5
, pp. 971-982
-
-
Braunstein, M.1
Anderson, M.K.2
-
18
-
-
33747623018
-
Notch signalling: a simple pathway becomes complex
-
Bray, S.J., Notch signalling: a simple pathway becomes complex. Nat. Rev. Mol. Cell. Biol. 7:9 (2006), 678–689.
-
(2006)
Nat. Rev. Mol. Cell. Biol.
, vol.7
, Issue.9
, pp. 678-689
-
-
Bray, S.J.1
-
19
-
-
79956303505
-
Three chemokine receptors cooperatively regulate homing of hematopoietic progenitors to the embryonic mouse thymus
-
Calderón, L., Boehm, T., Three chemokine receptors cooperatively regulate homing of hematopoietic progenitors to the embryonic mouse thymus. Proc. Natl. Acad. Sci. 108:18 (2011), 7517–7522.
-
(2011)
Proc. Natl. Acad. Sci.
, vol.108
, Issue.18
, pp. 7517-7522
-
-
Calderón, L.1
Boehm, T.2
-
20
-
-
33746334804
-
Kruppel-like factor 2 regulates thymocyte and T-cell migration
-
Carlson, C.M., Endrizzi, B.T., et al. Kruppel-like factor 2 regulates thymocyte and T-cell migration. Nature 442:7100 (2006), 299–302.
-
(2006)
Nature
, vol.442
, Issue.7100
, pp. 299-302
-
-
Carlson, C.M.1
Endrizzi, B.T.2
-
21
-
-
77954901331
-
Decision checkpoints in the thymus
-
Carpenter, A.C., Bosselut, R., Decision checkpoints in the thymus. Nat. Immunol. 11:8 (2010), 666–673.
-
(2010)
Nat. Immunol.
, vol.11
, Issue.8
, pp. 666-673
-
-
Carpenter, A.C.1
Bosselut, R.2
-
22
-
-
34047192398
-
Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development
-
Cejalvo, T., Sacedón, R., et al. Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development. Immunology 121:1 (2007), 94–104.
-
(2007)
Immunology
, vol.121
, Issue.1
, pp. 94-104
-
-
Cejalvo, T.1
Sacedón, R.2
-
23
-
-
0026076243
-
A pertussis toxin-sensitive process controls thymocyte emigration
-
Chaffin, K.E., Perlmutter, R.M., A pertussis toxin-sensitive process controls thymocyte emigration. Eur. J. Immunol. 21:10 (1991), 2565–2573.
-
(1991)
Eur. J. Immunol.
, vol.21
, Issue.10
, pp. 2565-2573
-
-
Chaffin, K.E.1
Perlmutter, R.M.2
-
24
-
-
33847211457
-
NOTCH1-induced T-cell leukemia in transgenic zebrafish
-
Chen, J., Jette, C., et al. NOTCH1-induced T-cell leukemia in transgenic zebrafish. Leukemia 21:3 (2007), 462–471.
-
(2007)
Leukemia
, vol.21
, Issue.3
, pp. 462-471
-
-
Chen, J.1
Jette, C.2
-
25
-
-
77953751851
-
Mouse and zebrafish Hoxa3 orthologues have nonequivalent in vivo protein function
-
Chen, L., Zhao, P., et al. Mouse and zebrafish Hoxa3 orthologues have nonequivalent in vivo protein function. Proc. Natl. Acad. Sci. USA 107:23 (2010), 10555–10560.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, Issue.23
, pp. 10555-10560
-
-
Chen, L.1
Zhao, P.2
-
26
-
-
77954858033
-
Genetic control of hematopoietic development in Xenopus and zebrafish
-
Ciau-Uitz, A., Liu, F., et al. Genetic control of hematopoietic development in Xenopus and zebrafish. Int. J. Dev. Biol. 54:6–7 (2010), 1139–1149.
-
(2010)
Int. J. Dev. Biol.
, vol.54
, Issue.6-7
, pp. 1139-1149
-
-
Ciau-Uitz, A.1
Liu, F.2
-
27
-
-
33745014890
-
Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation
-
Ciofani, M., Knowles, G.C., et al. Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation. Immunity 25:1 (2006), 105–116.
-
(2006)
Immunity
, vol.25
, Issue.1
, pp. 105-116
-
-
Ciofani, M.1
Knowles, G.C.2
-
28
-
-
24944444760
-
Notch promotes survival of pre–T cells at the β-selection checkpoint by regulating cellular metabolism
-
Ciofani, M., Zúñiga-Pflücker, J.C., Notch promotes survival of pre–T cells at the β-selection checkpoint by regulating cellular metabolism. Nat. Immunol. 6:9 (2005), 881–888.
-
(2005)
Nat. Immunol.
, vol.6
, Issue.9
, pp. 881-888
-
-
Ciofani, M.1
Zúñiga-Pflücker, J.C.2
-
29
-
-
38449106709
-
The thymus as an inductive site for T lymphopoiesis
-
Ciofani, M., Zúñiga-Pflücker, J.C., The thymus as an inductive site for T lymphopoiesis. Annu. Rev. Cell Dev. Biol. 23:1 (2007), 463–493.
-
(2007)
Annu. Rev. Cell Dev. Biol.
, vol.23
, Issue.1
, pp. 463-493
-
-
Ciofani, M.1
Zúñiga-Pflücker, J.C.2
-
30
-
-
78049276268
-
Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage
-
Corbeaux, T., Hess, I., et al. Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage. Proc. Natl. Acad. Sci. USA 107:38 (2010), 16613–16618.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, Issue.38
, pp. 16613-16618
-
-
Corbeaux, T.1
Hess, I.2
-
31
-
-
34548258170
-
Sonic hedgehog signalling in T-cell development and activation
-
Crompton, T., Outram, S.V., et al. Sonic hedgehog signalling in T-cell development and activation. Nat. Rev. Immunol. 7:9 (2007), 726–735.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, Issue.9
, pp. 726-735
-
-
Crompton, T.1
Outram, S.V.2
-
32
-
-
76949089741
-
An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells
-
D'Cruz, L.M., Knell, J., et al. An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells. Nat. Immunol. 11:3 (2010), 240–249.
-
(2010)
Nat. Immunol.
, vol.11
, Issue.3
, pp. 240-249
-
-
D'Cruz, L.M.1
Knell, J.2
-
33
-
-
1642362216
-
T cells and the thymus in developing zebrafish
-
Danilova, N., Hohman, V.S., et al. T cells and the thymus in developing zebrafish. Dev. Comp. Immunol. 28:7–8 (2004), 755–767.
-
(2004)
Dev. Comp. Immunol.
, vol.28
, Issue.7-8
, pp. 755-767
-
-
Danilova, N.1
Hohman, V.S.2
-
34
-
-
77954345079
-
A Guardian of T Cell Fate
-
Di Santo, J.P., A Guardian of T Cell Fate. Science 329:5987 (2010), 44–45.
-
(2010)
Science
, vol.329
, Issue.5987
, pp. 44-45
-
-
Di Santo, J.P.1
-
35
-
-
48749094942
-
E2A proteins promote development of lymphoid-primed multipotent progenitors
-
Dias, S., Mansson, R., et al. E2A proteins promote development of lymphoid-primed multipotent progenitors. Immunity 29:2 (2008), 217–227.
-
(2008)
Immunity
, vol.29
, Issue.2
, pp. 217-227
-
-
Dias, S.1
Mansson, R.2
-
36
-
-
0028962137
-
Undulated phenotypes suggest a role of Pax-1 for the development of vertebral and extravertebral structures
-
Dietrich, S., Gruss, P., Undulated phenotypes suggest a role of Pax-1 for the development of vertebral and extravertebral structures. Dev. Biol. 167:2 (1995), 529–548.
-
(1995)
Dev. Biol.
, vol.167
, Issue.2
, pp. 529-548
-
-
Dietrich, S.1
Gruss, P.2
-
37
-
-
77949879961
-
Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism
-
Do, J.S., Fink, P.J., et al. Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism. J. Immunol. 184:4 (2010), 1675–1679.
-
(2010)
J. Immunol.
, vol.184
, Issue.4
, pp. 1675-1679
-
-
Do, J.S.1
Fink, P.J.2
-
38
-
-
33646858664
-
Cervical thymus in the mouse
-
Dooley, J., Erickson, M., et al. Cervical thymus in the mouse. J. Immunol. 176:11 (2006), 6484–6490.
-
(2006)
J. Immunol.
, vol.176
, Issue.11
, pp. 6484-6490
-
-
Dooley, J.1
Erickson, M.2
-
39
-
-
77958470617
-
Non-redundant role for the transcription factor Gli1 at multiple stages of thymocyte development
-
Drakopoulou, E., Outram, S.V., et al. Non-redundant role for the transcription factor Gli1 at multiple stages of thymocyte development. Cell Cycle 9:20 (2010), 4144–4152.
-
(2010)
Cell Cycle
, vol.9
, Issue.20
, pp. 4144-4152
-
-
Drakopoulou, E.1
Outram, S.V.2
-
40
-
-
33645095936
-
Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus
-
El Andaloussi, A., Graves, S., et al. Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus. Nat. Immunol. 7:4 (2006), 418–426.
-
(2006)
Nat. Immunol.
, vol.7
, Issue.4
, pp. 418-426
-
-
El Andaloussi, A.1
Graves, S.2
-
41
-
-
0842285394
-
E2A proteins enforce a proliferation checkpoint in developing thymocytes
-
Engel, I., Murre, C., E2A proteins enforce a proliferation checkpoint in developing thymocytes. EMBO J. 23:1 (2004), 202–211.
-
(2004)
EMBO J.
, vol.23
, Issue.1
, pp. 202-211
-
-
Engel, I.1
Murre, C.2
-
42
-
-
58149251919
-
Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms
-
Feyerabend, T.B., Terszowski, G., et al. Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms. Immunity 30:1 (2009), 67–79.
-
(2009)
Immunity
, vol.30
, Issue.1
, pp. 67-79
-
-
Feyerabend, T.B.1
Terszowski, G.2
-
43
-
-
49649095672
-
IFN regulatory factor-1 negatively regulates CD4+ CD25+ regulatory T cell differentiation by repressing Foxp3 expression
-
Fragale, A., Gabriele, L., et al. IFN regulatory factor-1 negatively regulates CD4+ CD25+ regulatory T cell differentiation by repressing Foxp3 expression. J. Immunol. 181:3 (2008), 1673–1682.
-
(2008)
J. Immunol.
, vol.181
, Issue.3
, pp. 1673-1682
-
-
Fragale, A.1
Gabriele, L.2
-
44
-
-
18944379196
-
The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance
-
Fry, T.J., Mackall, C.L., The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. J. Immunol. 174:11 (2005), 6571–6576.
-
(2005)
J. Immunol.
, vol.174
, Issue.11
, pp. 6571-6576
-
-
Fry, T.J.1
Mackall, C.L.2
-
45
-
-
33745019824
-
Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate
-
Garbe, A.I., Krueger, A., et al. Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate. J. Exp. Med. 203:6 (2006), 1579–1590.
-
(2006)
J. Exp. Med.
, vol.203
, Issue.6
, pp. 1579-1590
-
-
Garbe, A.I.1
Krueger, A.2
-
46
-
-
0034963495
-
Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development
-
Garg, V., Yamagishi, C., et al. Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development. Dev. Biol. 235:1 (2001), 62–73.
-
(2001)
Dev. Biol.
, vol.235
, Issue.1
, pp. 62-73
-
-
Garg, V.1
Yamagishi, C.2
-
47
-
-
84055178955
-
T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling
-
Germar, K., Dose, M., et al. T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling. Proc. Natl. Acad. Sci. USA 108:50 (2011), 20060–20065.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, Issue.50
, pp. 20060-20065
-
-
Germar, K.1
Dose, M.2
-
48
-
-
62149148156
-
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration
-
Goessling, W., North, T.E., et al. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 136:6 (2009), 1136–1147.
-
(2009)
Cell
, vol.136
, Issue.6
, pp. 1136-1147
-
-
Goessling, W.1
North, T.E.2
-
49
-
-
0035005477
-
Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch
-
Gordon, J., Bennett, A.R., et al. Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch. Mech. Dev. 103:1–2 (2001), 141–143.
-
(2001)
Mech. Dev.
, vol.103
, Issue.1-2
, pp. 141-143
-
-
Gordon, J.1
Bennett, A.R.2
-
50
-
-
80051924092
-
Mechanisms of thymus organogenesis and morphogenesis
-
Gordon, J., Manley, N.R., Mechanisms of thymus organogenesis and morphogenesis. Development 138:18 (2011), 3865–3878.
-
(2011)
Development
, vol.138
, Issue.18
, pp. 3865-3878
-
-
Gordon, J.1
Manley, N.R.2
-
51
-
-
77649191415
-
Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis
-
Gordon, J., Patel, S.R., et al. Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis. Dev. Biol. 339:1 (2010), 141–154.
-
(2010)
Dev. Biol.
, vol.339
, Issue.1
, pp. 141-154
-
-
Gordon, J.1
Patel, S.R.2
-
52
-
-
2442647655
-
Functional evidence for a single endodermal origin for the thymic epithelium
-
Gordon, J., Wilson, V.A., et al. Functional evidence for a single endodermal origin for the thymic epithelium. Nat. Immunol. 5:5 (2004), 546–553.
-
(2004)
Nat. Immunol.
, vol.5
, Issue.5
, pp. 546-553
-
-
Gordon, J.1
Wilson, V.A.2
-
53
-
-
0035554684
-
Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development
-
Gounari, F., Aifantis, I., et al. Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development. Nat. Immunol. 2:9 (2001), 863–869.
-
(2001)
Nat. Immunol.
, vol.2
, Issue.9
, pp. 863-869
-
-
Gounari, F.1
Aifantis, I.2
-
54
-
-
23944472219
-
Loss of adenomatous polyposis coli gene function disrupts thymic development
-
Gounari, F., Chang, R., et al. Loss of adenomatous polyposis coli gene function disrupts thymic development. Nat. Immunol. 6:8 (2005), 800–809.
-
(2005)
Nat. Immunol.
, vol.6
, Issue.8
, pp. 800-809
-
-
Gounari, F.1
Chang, R.2
-
55
-
-
79955018467
-
Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids
-
Grevellec, A., Graham, A., et al. Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids. Dev. Biol. 353:2 (2011), 194–205.
-
(2011)
Dev. Biol.
, vol.353
, Issue.2
, pp. 194-205
-
-
Grevellec, A.1
Graham, A.2
-
56
-
-
70349235509
-
The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via Hedgehog-dependent and -independent mechanisms
-
Hager-Theodorides, A.L., Furmanski, A.L., et al. The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via Hedgehog-dependent and -independent mechanisms. J. Immunol. 183:5 (2009), 3023–3032.
-
(2009)
J. Immunol.
, vol.183
, Issue.5
, pp. 3023-3032
-
-
Hager-Theodorides, A.L.1
Furmanski, A.L.2
-
57
-
-
0037111391
-
Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation
-
Hager-Theodorides, A.L., Outram, S.V., et al. Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation. J. Immunol. 169:10 (2002), 5496–5504.
-
(2002)
J. Immunol.
, vol.169
, Issue.10
, pp. 5496-5504
-
-
Hager-Theodorides, A.L.1
Outram, S.V.2
-
58
-
-
71049160384
-
Prenatal cadmium exposure dysregulates sonic hedgehog and Wnt/beta-catenin signaling in the thymus resulting in altered thymocyte development
-
Hanson, M.L., Brundage, K.M., et al. Prenatal cadmium exposure dysregulates sonic hedgehog and Wnt/beta-catenin signaling in the thymus resulting in altered thymocyte development. Toxicol. Appl. Pharmacol. 242:2 (2010), 136–145.
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.242
, Issue.2
, pp. 136-145
-
-
Hanson, M.L.1
Brundage, K.M.2
-
59
-
-
50949123978
-
TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution
-
Hauri-Hohl, M.M., Zuklys, S., et al. TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution. Blood 112:3 (2008), 626–634.
-
(2008)
Blood
, vol.112
, Issue.3
, pp. 626-634
-
-
Hauri-Hohl, M.M.1
Zuklys, S.2
-
60
-
-
0033573003
-
Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation
-
Heanue, T.A., Reshef, R., et al. Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation. Genes Dev. 13:24 (1999), 3231–3243.
-
(1999)
Genes Dev.
, vol.13
, Issue.24
, pp. 3231-3243
-
-
Heanue, T.A.1
Reshef, R.2
-
61
-
-
33645091616
-
Cellular and molecular events during early thymus development
-
Hollander, G., Gill, J., et al. Cellular and molecular events during early thymus development. Immunol. Rev. 209 (2006), 28–46.
-
(2006)
Immunol. Rev.
, vol.209
, pp. 28-46
-
-
Hollander, G.1
Gill, J.2
-
62
-
-
85190492912
-
-
The mych gene is required for neural crest survival during zebrafish development. PLoS One 3 (4).
-
Hong, S.K., Tsang, M., et al., 2008. The mych gene is required for neural crest survival during zebrafish development. PLoS One 3 (4).
-
(2008)
-
-
Hong, S.K.1
Tsang, M.2
-
63
-
-
73949143689
-
GATA-3 is required for early T lineage progenitor development
-
Hosoya, T., Kuroha, T., et al. GATA-3 is required for early T lineage progenitor development. J. Exp. Med. 206:13 (2009), 2987–3000.
-
(2009)
J. Exp. Med.
, vol.206
, Issue.13
, pp. 2987-3000
-
-
Hosoya, T.1
Kuroha, T.2
-
64
-
-
45749086109
-
ICAT expression disrupts beta-catenin-TCF interactions and impairs survival of thymocytes and activated mature T cells
-
Hossain, M.Z., Yu, Q., et al. ICAT expression disrupts beta-catenin-TCF interactions and impairs survival of thymocytes and activated mature T cells. Int. Immunol. 20:7 (2008), 925–935.
-
(2008)
Int. Immunol.
, vol.20
, Issue.7
, pp. 925-935
-
-
Hossain, M.Z.1
Yu, Q.2
-
65
-
-
58149154746
-
Delta-like 4 is indispensable in thymic environment specific for T cell development
-
Hozumi, K., Mailhos, C., et al. Delta-like 4 is indispensable in thymic environment specific for T cell development. J. Exp. Med. 205:11 (2008), 2507–2513.
-
(2008)
J. Exp. Med.
, vol.205
, Issue.11
, pp. 2507-2513
-
-
Hozumi, K.1
Mailhos, C.2
-
66
-
-
9444265974
-
Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors
-
Hu, T., Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development 131:21 (2004), 5491–5502.
-
(2004)
Development
, vol.131
, Issue.21
, pp. 5491-5502
-
-
Hu, T.1
-
67
-
-
0035575988
-
Cutting edge: histone acetylation and recombination at the TCR gamma locus follows IL-7 induction
-
Huang, J., Durum, S.K., et al. Cutting edge: histone acetylation and recombination at the TCR gamma locus follows IL-7 induction. J. Immunol. 167:11 (2001), 6073–6077.
-
(2001)
J. Immunol.
, vol.167
, Issue.11
, pp. 6073-6077
-
-
Huang, J.1
Durum, S.K.2
-
68
-
-
77954321988
-
An essential developmental checkpoint for production of the T cell lineage
-
Ikawa, T., Hirose, S., et al. An essential developmental checkpoint for production of the T cell lineage. Science 329:5987 (2010), 93–96.
-
(2010)
Science
, vol.329
, Issue.5987
, pp. 93-96
-
-
Ikawa, T.1
Hirose, S.2
-
69
-
-
33846613211
-
Expression of Dll4 and CCL25 in Foxn1-negative epithelial cells in the post-natal thymus
-
Itoi, M., Tsukamoto, N., et al. Expression of Dll4 and CCL25 in Foxn1-negative epithelial cells in the post-natal thymus. Int. Immunol. 19:2 (2006), 127–132.
-
(2006)
Int. Immunol.
, vol.19
, Issue.2
, pp. 127-132
-
-
Itoi, M.1
Tsukamoto, N.2
-
70
-
-
79959547458
-
Genetic evidence for an evolutionarily conserved role of IL-7 signaling in T cell development of zebrafish
-
Iwanami, N., Mateos, F., et al. Genetic evidence for an evolutionarily conserved role of IL-7 signaling in T cell development of zebrafish. J. Immunol. 186:12 (2011), 7060–7066.
-
(2011)
J. Immunol.
, vol.186
, Issue.12
, pp. 7060-7066
-
-
Iwanami, N.1
Mateos, F.2
-
72
-
-
55749107446
-
Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells
-
Jeker, L.T., Barthlott, T., et al. Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells. Blood 112:9 (2008), 3688–3695.
-
(2008)
Blood
, vol.112
, Issue.9
, pp. 3688-3695
-
-
Jeker, L.T.1
Barthlott, T.2
-
73
-
-
0035098557
-
DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1
-
Jerome, L.A., Papaioannou, V.E., DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1. Nat. Genet. 27:3 (2001), 286–291.
-
(2001)
Nat. Genet.
, vol.27
, Issue.3
, pp. 286-291
-
-
Jerome, L.A.1
Papaioannou, V.E.2
-
74
-
-
0035005044
-
Concurrent expression of recombination activating genes 1 and 2 in zebrafish olfactory sensory neurons
-
Jessen, J.R., Jessen, T.N., et al. Concurrent expression of recombination activating genes 1 and 2 in zebrafish olfactory sensory neurons. Genesis 29:4 (2001), 156–162.
-
(2001)
Genesis
, vol.29
, Issue.4
, pp. 156-162
-
-
Jessen, J.R.1
Jessen, T.N.2
-
75
-
-
0032823414
-
Artificial chromosome transgenesis reveals long-distance negative regulation of rag1 in zebrafish
-
Jessen, J.R., Willett, C.E., et al. Artificial chromosome transgenesis reveals long-distance negative regulation of rag1 in zebrafish. Nat. Genet. 23:1 (1999), 15–16.
-
(1999)
Nat. Genet.
, vol.23
, Issue.1
, pp. 15-16
-
-
Jessen, J.R.1
Willett, C.E.2
-
76
-
-
2442642680
-
The role of hoxa3 gene in parathyroid gland organogenesis of the mouse
-
Kameda, Y., Arai, Y., et al. The role of hoxa3 gene in parathyroid gland organogenesis of the mouse. J. Histochem. Cytochem. 52:5 (2004), 641–651.
-
(2004)
J. Histochem. Cytochem.
, vol.52
, Issue.5
, pp. 641-651
-
-
Kameda, Y.1
Arai, Y.2
-
77
-
-
0035911172
-
Evidence that gammadelta versus alphabeta T cell fate determination is initiated independently of T cell receptor signaling
-
Kang, J., Volkmann, A., et al. Evidence that gammadelta versus alphabeta T cell fate determination is initiated independently of T cell receptor signaling. J. Exp. Med. 193:6 (2001), 689–698.
-
(2001)
J. Exp. Med.
, vol.193
, Issue.6
, pp. 689-698
-
-
Kang, J.1
Volkmann, A.2
-
78
-
-
61349152914
-
E and ID proteins branch out
-
Kee, B.L., E and ID proteins branch out. Nat. Rev. Immunol. 9:3 (2009), 175–184.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, Issue.3
, pp. 175-184
-
-
Kee, B.L.1
-
79
-
-
78650085394
-
Foxo transcription factors control regulatory T cell development and function
-
Kerdiles, Y.M., Stone, E.L., et al. Foxo transcription factors control regulatory T cell development and function. Immunity 33:6 (2010), 890–904.
-
(2010)
Immunity
, vol.33
, Issue.6
, pp. 890-904
-
-
Kerdiles, Y.M.1
Stone, E.L.2
-
80
-
-
0022780155
-
Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors
-
Kidd, S., Kelley, M.R., et al. Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors. Mol. Cell. Biol. 6:9 (1986), 3094–3108.
-
(1986)
Mol. Cell. Biol.
, vol.6
, Issue.9
, pp. 3094-3108
-
-
Kidd, S.1
Kelley, M.R.2
-
81
-
-
38949126943
-
Live imaging of emerging hematopoietic stem cells and early thymus colonization
-
Kissa, K., Murayama, E., et al. Live imaging of emerging hematopoietic stem cells and early thymus colonization. Blood 111:3 (2008), 1147–1156.
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1147-1156
-
-
Kissa, K.1
Murayama, E.2
-
82
-
-
57349122315
-
Ikaros represses the transcriptional response to Notch signaling in T-cell development
-
Kleinmann, E., Geimer Le Lay, A.S., et al. Ikaros represses the transcriptional response to Notch signaling in T-cell development. Mol. Cell. Biol. 28:24 (2008), 7465–7475.
-
(2008)
Mol. Cell. Biol.
, vol.28
, Issue.24
, pp. 7465-7475
-
-
Kleinmann, E.1
Geimer Le Lay, A.S.2
-
83
-
-
0036498798
-
Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis
-
Ko, J., Gendron-Fitzpatrick, A., et al. Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis. J. Immunol. 168:5 (2002), 2433–2440.
-
(2002)
J. Immunol.
, vol.168
, Issue.5
, pp. 2433-2440
-
-
Ko, J.1
Gendron-Fitzpatrick, A.2
-
84
-
-
58149151302
-
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment
-
Koch, U., Fiorini, E., et al. Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. J. Exp. Med. 205:11 (2008), 2515–2523.
-
(2008)
J. Exp. Med.
, vol.205
, Issue.11
, pp. 2515-2523
-
-
Koch, U.1
Fiorini, E.2
-
85
-
-
0043287957
-
Cloning and characterization of zebrafish tbx1
-
Kochilas, L.K., Potluri, V., et al. Cloning and characterization of zebrafish tbx1. Gene Expression Patterns 3:5 (2003), 645–651.
-
(2003)
Gene Expression Patterns
, vol.3
, Issue.5
, pp. 645-651
-
-
Kochilas, L.K.1
Potluri, V.2
-
86
-
-
70349339369
-
Beta-catenin/Tcf determines the outcome of thymic selection in response to alphabetaTCR signaling
-
Kovalovsky, D., Yu, Y., et al. Beta-catenin/Tcf determines the outcome of thymic selection in response to alphabetaTCR signaling. J. Immunol. 183:6 (2009), 3873–3884.
-
(2009)
J. Immunol.
, vol.183
, Issue.6
, pp. 3873-3884
-
-
Kovalovsky, D.1
Yu, Y.2
-
87
-
-
85190489374
-
-
Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence. PLoS One 5 (5).
-
Kvell, K., Varecza, Z., et al., 2010. Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence. PLoS One 5 (5).
-
(2010)
-
-
Kvell, K.1
Varecza, Z.2
-
88
-
-
77956544161
-
Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells
-
Lam, E.Y., Hall, C.J., et al. Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells. Blood 116:6 (2010), 909–914.
-
(2010)
Blood
, vol.116
, Issue.6
, pp. 909-914
-
-
Lam, E.Y.1
Hall, C.J.2
-
89
-
-
0036729258
-
Morphologic transformation of the thymus in developing zebrafish
-
Lam, S.H., Chua, H.L., et al. Morphologic transformation of the thymus in developing zebrafish. Dev. Dyn. 225:1 (2002), 87–94.
-
(2002)
Dev. Dyn.
, vol.225
, Issue.1
, pp. 87-94
-
-
Lam, S.H.1
Chua, H.L.2
-
90
-
-
79961011574
-
Sipl1 and rbck1 are novel eya1-binding proteins with a role in craniofacial development
-
Landgraf, K., Bollig, F., et al. Sipl1 and rbck1 are novel eya1-binding proteins with a role in craniofacial development. Mol. Cell. Biol. 30:24 (2010), 5764–5775.
-
(2010)
Mol. Cell. Biol.
, vol.30
, Issue.24
, pp. 5764-5775
-
-
Landgraf, K.1
Bollig, F.2
-
91
-
-
2442599273
-
In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish
-
Langenau, D.M., In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proc. Nat. Acad. Sci. 101:19 (2004), 7369–7374.
-
(2004)
Proc. Nat. Acad. Sci.
, vol.101
, Issue.19
, pp. 7369-7374
-
-
Langenau, D.M.1
-
92
-
-
17144367704
-
The zebrafish: a new model of T-cell and thymic development
-
Langenau, D.M., Zon, L.I., The zebrafish: a new model of T-cell and thymic development. Nat. Rev. Immunol. 5:4 (2005), 307–317.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, Issue.4
, pp. 307-317
-
-
Langenau, D.M.1
Zon, L.I.2
-
93
-
-
0035889144
-
Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells
-
Langerak, A.W., Wolvers-Tettero, I.L., et al. Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells. Blood 98:8 (2001), 2456–2465.
-
(2001)
Blood
, vol.98
, Issue.8
, pp. 2456-2465
-
-
Langerak, A.W.1
Wolvers-Tettero, I.L.2
-
94
-
-
85190492577
-
-
Induction of tolerance by embryonic thymic epithelial grafts in birds and mammals. Cold Spring Harb. Symp. Quant. Biol. 54 (Pt 2), 777–787.
-
Le Douarin, N.M., Corbel, C., et al., 1989. Induction of tolerance by embryonic thymic epithelial grafts in birds and mammals. Cold Spring Harb. Symp. Quant. Biol. 54 (Pt 2), 777–787.
-
(1989)
-
-
Le Douarin, N.M.1
Corbel, C.2
-
95
-
-
79951715831
-
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
-
Lei, Y., Ripen, A., et al. Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development. J. Exp. Med. 208:2 (2011), 383–394.
-
(2011)
J. Exp. Med.
, vol.208
, Issue.2
, pp. 383-394
-
-
Lei, Y.1
Ripen, A.2
-
96
-
-
36749066715
-
Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice
-
Li, J., Li, Y., et al. Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice. Proc. Natl. Acad. Sci. USA 104:46 (2007), 18175–18180.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.46
, pp. 18175-18180
-
-
Li, J.1
Li, Y.2
-
97
-
-
77954329976
-
An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b
-
Li, L., Leid, M., et al. An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b. Science 329:5987 (2010), 89–93.
-
(2010)
Science
, vol.329
, Issue.5987
, pp. 89-93
-
-
Li, L.1
Leid, M.2
-
98
-
-
77954326626
-
Reprogramming of T Cells to natural killer–like cells upon Bcl11b deletion
-
Li, P., Burke, S., et al. Reprogramming of T Cells to natural killer–like cells upon Bcl11b deletion. Science 329:5987 (2010), 85–89.
-
(2010)
Science
, vol.329
, Issue.5987
, pp. 85-89
-
-
Li, P.1
Burke, S.2
-
99
-
-
84892674074
-
Notch signaling in T-cell development and T-all
-
Li, X., von Boehmer, H., Notch signaling in T-cell development and T-all. ISRN Hematol. 2011 (2011), 1–9.
-
(2011)
ISRN Hematol.
, vol.2011
, pp. 1-9
-
-
Li, X.1
von Boehmer, H.2
-
100
-
-
37549021795
-
Noncanonical Wnt signaling promotes apoptosis in thymocyte development
-
Liang, H., Coles, A.H., et al. Noncanonical Wnt signaling promotes apoptosis in thymocyte development. J. Exp. Med. 204:13 (2007), 3077–3084.
-
(2007)
J. Exp. Med.
, vol.204
, Issue.13
, pp. 3077-3084
-
-
Liang, H.1
Coles, A.H.2
-
101
-
-
6944227821
-
Requirement of c-myb in T cell development and in mature T cell function
-
Lieu, Y.K., Kumar, A., et al. Requirement of c-myb in T cell development and in mature T cell function. Proc. Natl. Acad. Sci. USA 101:41 (2004), 14853–14858.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.41
, pp. 14853-14858
-
-
Lieu, Y.K.1
Kumar, A.2
-
102
-
-
67649292604
-
The transcription factor Six1a plays an essential role in the craniofacial myogenesis of zebrafish
-
Lin, C.-Y., Chen, W.-T., et al. The transcription factor Six1a plays an essential role in the craniofacial myogenesis of zebrafish. Dev. Biol. 331:2 (2009), 152–166.
-
(2009)
Dev. Biol.
, vol.331
, Issue.2
, pp. 152-166
-
-
Lin, C.-Y.1
Chen, W.-T.2
-
103
-
-
77958553288
-
Critical roles of Bcl11b in T-cell development and maintenance of T-cell identity
-
Liu, P., Li, P., et al. Critical roles of Bcl11b in T-cell development and maintenance of T-cell identity. Immunol. Rev. 238:1 (2010), 138–149.
-
(2010)
Immunol. Rev.
, vol.238
, Issue.1
, pp. 138-149
-
-
Liu, P.1
Li, P.2
-
104
-
-
79959646651
-
Signal integration and crosstalk during thymocyte migration and emigration
-
Love, P.E., Bhandoola, A., Signal integration and crosstalk during thymocyte migration and emigration. Nat. Rev. Immunol. 11:7 (2011), 469–477.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, Issue.7
, pp. 469-477
-
-
Love, P.E.1
Bhandoola, A.2
-
105
-
-
67650230896
-
Wnt/beta-catenin signaling: components, mechanisms, and diseases
-
MacDonald, B.T., Tamai, K., et al. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell 17:1 (2009), 9–26.
-
(2009)
Dev. Cell
, vol.17
, Issue.1
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
-
106
-
-
34248580502
-
Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF
-
Maeda, T., Merghoub, T., et al. Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF. Science 316:5826 (2007), 860–866.
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 860-866
-
-
Maeda, T.1
Merghoub, T.2
-
107
-
-
0030442579
-
The V-J recombination of T cell receptor-gamma genes is blocked in interleukin-7 receptor-deficient mice
-
Maki, K., Sunaga, S., et al. The V-J recombination of T cell receptor-gamma genes is blocked in interleukin-7 receptor-deficient mice. J. Exp. Med. 184:6 (1996), 2423–2427.
-
(1996)
J. Exp. Med.
, vol.184
, Issue.6
, pp. 2423-2427
-
-
Maki, K.1
Sunaga, S.2
-
108
-
-
70349659643
-
A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans
-
Mandinova, A., Kolev, V., et al. A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans. J. Clin. Invest. 119:10 (2009), 3127–3137.
-
(2009)
J. Clin. Invest.
, vol.119
, Issue.10
, pp. 3127-3137
-
-
Mandinova, A.1
Kolev, V.2
-
109
-
-
0033753252
-
Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation
-
Manley, N.R., Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation. Semin. Immunol. 12:5 (2000), 421–428.
-
(2000)
Semin. Immunol.
, vol.12
, Issue.5
, pp. 421-428
-
-
Manley, N.R.1
-
110
-
-
0029030722
-
The role of Hoxa-3 in mouse thymus and thyroid development
-
Manley, N.R., Capecchi, M.R., The role of Hoxa-3 in mouse thymus and thyroid development. Development 121:7 (1995), 1989–2003.
-
(1995)
Development
, vol.121
, Issue.7
, pp. 1989-2003
-
-
Manley, N.R.1
Capecchi, M.R.2
-
111
-
-
77958126305
-
Transcriptional regulation of thymus organogenesis and thymic epithelial cell differentiation
-
Manley, N.R., Condie, B.G., Transcriptional regulation of thymus organogenesis and thymic epithelial cell differentiation. Prog. Mol. Biol. Transl Sci. 92 (2010), 103–120.
-
(2010)
Prog. Mol. Biol. Transl Sci.
, vol.92
, pp. 103-120
-
-
Manley, N.R.1
Condie, B.G.2
-
112
-
-
33847242598
-
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
-
Marson, A., Kretschmer, K., et al. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature 445:7130 (2007), 931–935.
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 931-935
-
-
Marson, A.1
Kretschmer, K.2
-
114
-
-
1642580757
-
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
-
Matloubian, M., Lo, C.G., et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427:6972 (2004), 355–360.
-
(2004)
Nature
, vol.427
, Issue.6972
, pp. 355-360
-
-
Matloubian, M.1
Lo, C.G.2
-
115
-
-
75149113532
-
Characterization of the zebrafish T cell receptor beta locus
-
Meeker, N.D., Smith, A.C., et al. Characterization of the zebrafish T cell receptor beta locus. Immunogenetics 62:1 (2010), 23–29.
-
(2010)
Immunogenetics
, vol.62
, Issue.1
, pp. 23-29
-
-
Meeker, N.D.1
Smith, A.C.2
-
116
-
-
33846785428
-
Integrated morphogen signal inputs in gammadelta versus alphabeta T-cell differentiation
-
Melichar, H., Kang, J., Integrated morphogen signal inputs in gammadelta versus alphabeta T-cell differentiation. Immunol. Rev. 215 (2007), 32–45.
-
(2007)
Immunol. Rev.
, vol.215
, pp. 32-45
-
-
Melichar, H.1
Kang, J.2
-
117
-
-
33846487941
-
Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13
-
Melichar, H.J., Narayan, K., et al. Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13. Science 315:5809 (2007), 230–233.
-
(2007)
Science
, vol.315
, Issue.5809
, pp. 230-233
-
-
Melichar, H.J.1
Narayan, K.2
-
118
-
-
49749221890
-
Immunological function of the thymus
-
Miller, J.F., Immunological function of the thymus. Lancet 2:7205 (1961), 748–749.
-
(1961)
Lancet
, vol.2
, Issue.7205
, pp. 748-749
-
-
Miller, J.F.1
-
119
-
-
73649105181
-
Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio
-
Mitra, S., Alnabulsi, A., et al. Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio. FEBS J. 277:1 (2010), 128–147.
-
(2010)
FEBS J.
, vol.277
, Issue.1
, pp. 128-147
-
-
Mitra, S.1
Alnabulsi, A.2
-
120
-
-
36548999223
-
Ets-1 is a negative regulator of Th17 differentiation
-
Moisan, J., Grenningloh, R., et al. Ets-1 is a negative regulator of Th17 differentiation. J. Exp. Med. 204:12 (2007), 2825–2835.
-
(2007)
J. Exp. Med.
, vol.204
, Issue.12
, pp. 2825-2835
-
-
Moisan, J.1
Grenningloh, R.2
-
121
-
-
71349086796
-
Foxn1 is essential for vascularization of the murine thymus anlage
-
Mori, K., Itoi, M., et al. Foxn1 is essential for vascularization of the murine thymus anlage. Cell. Immunol. 260:2 (2010), 66–69.
-
(2010)
Cell. Immunol.
, vol.260
, Issue.2
, pp. 66-69
-
-
Mori, K.1
Itoi, M.2
-
122
-
-
0032441457
-
Retinoic acid-induced thymic abnormalities in the mouse are associated with altered pharyngeal morphology, thymocyte maturation defects, and altered expression of Hoxa3 and Pax1
-
Mulder, G.B., Manley, N., et al. Retinoic acid-induced thymic abnormalities in the mouse are associated with altered pharyngeal morphology, thymocyte maturation defects, and altered expression of Hoxa3 and Pax1. Teratology 58:6 (1998), 263–275.
-
(1998)
Teratology
, vol.58
, Issue.6
, pp. 263-275
-
-
Mulder, G.B.1
Manley, N.2
-
123
-
-
0036232701
-
Wnt-1 and Wnt-4 regulate thymic cellularity
-
Mulroy, T., McMahon, J.A., et al. Wnt-1 and Wnt-4 regulate thymic cellularity. Eur. J. Immunol. 32:4 (2002), 967–971.
-
(2002)
Eur. J. Immunol.
, vol.32
, Issue.4
, pp. 967-971
-
-
Mulroy, T.1
McMahon, J.A.2
-
124
-
-
33845448620
-
Tracing hematopoietic precursor migration to successive hematopoietic organs during zebrafish development
-
Murayama, E., Kissa, K., et al. Tracing hematopoietic precursor migration to successive hematopoietic organs during zebrafish development. Immunity 25:6 (2006), 963–975.
-
(2006)
Immunity
, vol.25
, Issue.6
, pp. 963-975
-
-
Murayama, E.1
Kissa, K.2
-
125
-
-
80055109080
-
Transcriptional control of T-cell development
-
Naito, T., Tanaka, H., et al. Transcriptional control of T-cell development. Int. Immunol. 23:11 (2011), 661–668.
-
(2011)
Int. Immunol.
, vol.23
, Issue.11
, pp. 661-668
-
-
Naito, T.1
Tanaka, H.2
-
126
-
-
0029920145
-
Two genetically separable steps in the differentiation of thymic epithelium
-
Nehls, M., Kyewski, B., et al. Two genetically separable steps in the differentiation of thymic epithelium. Science 272:5263 (1996), 886–889.
-
(1996)
Science
, vol.272
, Issue.5263
, pp. 886-889
-
-
Nehls, M.1
Kyewski, B.2
-
127
-
-
0028000121
-
New member of the winged-helix protein family disrupted in mouse and rat nude mutations
-
Nehls, M., Pfeifer, D., et al. New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature 372:6501 (1994), 103–107.
-
(1994)
Nature
, vol.372
, Issue.6501
, pp. 103-107
-
-
Nehls, M.1
Pfeifer, D.2
-
128
-
-
84355161498
-
Modulation of Bmp4 signalling in the epithelial–mesenchymal interactions that take place in early thymus and parathyroid development in avian embryos
-
Neves, H., Dupin, E., et al. Modulation of Bmp4 signalling in the epithelial–mesenchymal interactions that take place in early thymus and parathyroid development in avian embryos. Dev. Biol. 361:2 (2011), 208–219.
-
(2011)
Dev. Biol.
, vol.361
, Issue.2
, pp. 208-219
-
-
Neves, H.1
Dupin, E.2
-
129
-
-
33645735330
-
Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis
-
Nica, G., Herzog, W., et al. Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis. Dev. Biol. 292:1 (2006), 189–204.
-
(2006)
Dev. Biol.
, vol.292
, Issue.1
, pp. 189-204
-
-
Nica, G.1
Herzog, W.2
-
130
-
-
0029911097
-
Zebrafish Pax9 encodes two proteins with distinct C-terminal transactivating domains of different potency negatively regulated by adjacent N-terminal sequences
-
Nornes, S., Mikkola, I., et al. Zebrafish Pax9 encodes two proteins with distinct C-terminal transactivating domains of different potency negatively regulated by adjacent N-terminal sequences. J. Biol. Chem. 271:43 (1996), 26914–26923.
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.43
, pp. 26914-26923
-
-
Nornes, S.1
Mikkola, I.2
-
131
-
-
37549021100
-
Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation
-
Ohno, S., Sato, T., et al. Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation. Int. Immunol. 20:1 (2008), 71–79.
-
(2008)
Int. Immunol.
, vol.20
, Issue.1
, pp. 71-79
-
-
Ohno, S.1
Sato, T.2
-
132
-
-
0031883962
-
Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1
-
Okamura, R.M., Sigvardsson, M., et al. Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1. Immunity 8:1 (1998), 11–20.
-
(1998)
Immunity
, vol.8
, Issue.1
, pp. 11-20
-
-
Okamura, R.M.1
Sigvardsson, M.2
-
133
-
-
0030061554
-
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
-
Okuda, T., van Deursen, J., et al. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84:2 (1996), 321–330.
-
(1996)
Cell
, vol.84
, Issue.2
, pp. 321-330
-
-
Okuda, T.1
van Deursen, J.2
-
134
-
-
39349096526
-
Hematopoiesis: an evolving paradigm for stem cell biology
-
Orkin, S.H., Zon, L.I., Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132:4 (2008), 631–644.
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 631-644
-
-
Orkin, S.H.1
Zon, L.I.2
-
135
-
-
33845609951
-
The Wnt signaling antagonist Kremen1 is required for development of thymic architecture
-
Osada, M., Ito, E., et al. The Wnt signaling antagonist Kremen1 is required for development of thymic architecture. Clin. Dev. Immunol. 13:2–4 (2006), 299–319.
-
(2006)
Clin. Dev. Immunol.
, vol.13
, Issue.2-4
, pp. 299-319
-
-
Osada, M.1
Ito, E.2
-
136
-
-
77949378933
-
DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration
-
Osada, M., Jardine, L., et al. DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration. PLoS One, 5(2), 2010, e9062.
-
(2010)
PLoS One
, vol.5
, Issue.2
, pp. e9062
-
-
Osada, M.1
Jardine, L.2
-
137
-
-
64049114135
-
Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation
-
Outram, S.V., Hager-Theodorides, A.L., et al. Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation. Blood 113:10 (2009), 2217–2228.
-
(2009)
Blood
, vol.113
, Issue.10
, pp. 2217-2228
-
-
Outram, S.V.1
Hager-Theodorides, A.L.2
-
138
-
-
0033712944
-
Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte
-
Outram, S.V., Varas, A., et al. Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte. Immunity 13:2 (2000), 187–197.
-
(2000)
Immunity
, vol.13
, Issue.2
, pp. 187-197
-
-
Outram, S.V.1
Varas, A.2
-
139
-
-
77953267301
-
Transforming growth factor-β signaling curbs thymic negative selection promoting regulatory T cell development
-
Ouyang, W., Beckett, O., et al. Transforming growth factor-β signaling curbs thymic negative selection promoting regulatory T cell development. Immunity 32:5 (2010), 642–653.
-
(2010)
Immunity
, vol.32
, Issue.5
, pp. 642-653
-
-
Ouyang, W.1
Beckett, O.2
-
140
-
-
33748375176
-
Bmp4 and Noggin expression during early thymus and parathyroid organogenesis
-
Patel, S.R., Gordon, J., et al. Bmp4 and Noggin expression during early thymus and parathyroid organogenesis. Gene Expression Patterns 6:8 (2006), 794–799.
-
(2006)
Gene Expression Patterns
, vol.6
, Issue.8
, pp. 794-799
-
-
Patel, S.R.1
Gordon, J.2
-
141
-
-
33749327182
-
The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor
-
Pear, W.S., Maillard, I., et al. The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. J. Exp. Med. 203:10 (2006), 2239–2245.
-
(2006)
J. Exp. Med.
, vol.203
, Issue.10
, pp. 2239-2245
-
-
Pear, W.S.1
Maillard, I.2
-
142
-
-
0027988545
-
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
-
Peschon, J.J., Morrissey, P.J., et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 180:5 (1994), 1955–1960.
-
(1994)
J. Exp. Med.
, vol.180
, Issue.5
, pp. 1955-1960
-
-
Peschon, J.J.1
Morrissey, P.J.2
-
143
-
-
0032169255
-
Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities
-
Peters, H., Neubuser, A., et al. Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev. 12:17 (1998), 2735–2747.
-
(1998)
Genes Dev.
, vol.12
, Issue.17
, pp. 2735-2747
-
-
Peters, H.1
Neubuser, A.2
-
144
-
-
0142149329
-
The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans
-
Piotrowski, T., The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development 130:20 (2003), 5043–5052.
-
(2003)
Development
, vol.130
, Issue.20
, pp. 5043-5052
-
-
Piotrowski, T.1
-
145
-
-
33748865306
-
Overexpression of ICAT highlights a role for catenin-mediated canonical Wnt signalling in early T cell development
-
Pongracz, J.E., Parnell, S.M., et al. Overexpression of ICAT highlights a role for catenin-mediated canonical Wnt signalling in early T cell development. Eur. J. Immunol. 36:9 (2006), 2376–2383.
-
(2006)
Eur. J. Immunol.
, vol.36
, Issue.9
, pp. 2376-2383
-
-
Pongracz, J.E.1
Parnell, S.M.2
-
146
-
-
2942516896
-
Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages
-
Porritt, H.E., Rumfelt, L.L., et al. Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 20:6 (2004), 735–745.
-
(2004)
Immunity
, vol.20
, Issue.6
, pp. 735-745
-
-
Porritt, H.E.1
Rumfelt, L.L.2
-
147
-
-
0031740732
-
Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency
-
Puel, A., Ziegler, S.F., et al. Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. Nat. Genet. 20:4 (1998), 394–397.
-
(1998)
Nat. Genet.
, vol.20
, Issue.4
, pp. 394-397
-
-
Puel, A.1
Ziegler, S.F.2
-
148
-
-
77949721547
-
Adaptive autoimmunity and Foxp3-based immunoregulation in zebrafish
-
Quintana, F.J., Iglesias, A.H., et al. Adaptive autoimmunity and Foxp3-based immunoregulation in zebrafish. PLoS One, 5(3), 2010, e9478.
-
(2010)
PLoS One
, vol.5
, Issue.3
, pp. e9478
-
-
Quintana, F.J.1
Iglesias, A.H.2
-
149
-
-
74549176827
-
Notch signaling in the immune system
-
Radtke, F., Fasnacht, N., et al. Notch signaling in the immune system. Immunity 32:1 (2010), 14–27.
-
(2010)
Immunity
, vol.32
, Issue.1
, pp. 14-27
-
-
Radtke, F.1
Fasnacht, N.2
-
150
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke, F., Wilson, A., et al. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10:5 (1999), 547–558.
-
(1999)
Immunity
, vol.10
, Issue.5
, pp. 547-558
-
-
Radtke, F.1
Wilson, A.2
-
151
-
-
42649138855
-
Thymus Organogenesis
-
Rodewald, H.-R., Thymus Organogenesis. Ann. Rev. Immunol. 26:1 (2008), 355–388.
-
(2008)
Ann. Rev. Immunol.
, vol.26
, Issue.1
, pp. 355-388
-
-
Rodewald, H.-R.1
-
152
-
-
0035856960
-
Thymus medulla consisting of epithelial islets each derived from a single progenitor
-
Rodewald, H.R., Paul, S., et al. Thymus medulla consisting of epithelial islets each derived from a single progenitor. Nature 414:6865 (2001), 763–768.
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 763-768
-
-
Rodewald, H.R.1
Paul, S.2
-
153
-
-
0034667634
-
A partial deficiency of interleukin-7R alpha is sufficient to abrogate T-cell development and cause severe combined immunodeficiency
-
Roifman, C.M., Zhang, J., et al. A partial deficiency of interleukin-7R alpha is sufficient to abrogate T-cell development and cause severe combined immunodeficiency. Blood 96:8 (2000), 2803–2807.
-
(2000)
Blood
, vol.96
, Issue.8
, pp. 2803-2807
-
-
Roifman, C.M.1
Zhang, J.2
-
154
-
-
20644462119
-
Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1
-
Rossi, F.M., Corbel, S.Y., et al. Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1. Nat. Immunol. 6:6 (2005), 626–634.
-
(2005)
Nat. Immunol.
, vol.6
, Issue.6
, pp. 626-634
-
-
Rossi, F.M.1
Corbel, S.Y.2
-
155
-
-
37549010335
-
Launching the T-cell-lineage developmental programme
-
Rothenberg, E.V., Moore, J.E., et al. Launching the T-cell-lineage developmental programme. Nat. Rev. Immunol. 8:1 (2008), 9–21.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, Issue.1
, pp. 9-21
-
-
Rothenberg, E.V.1
Moore, J.E.2
-
156
-
-
67149147423
-
Sonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanism
-
Rowbotham, N.J., Hager-Theodorides, A.L., et al. Sonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanism. Blood 113:21 (2009), 5144–5156.
-
(2009)
Blood
, vol.113
, Issue.21
, pp. 5144-5156
-
-
Rowbotham, N.J.1
Hager-Theodorides, A.L.2
-
157
-
-
0032532301
-
Critical involvement of Tcf-1 in expansion of thymocytes
-
Schilham, M.W., Wilson, A., et al. Critical involvement of Tcf-1 in expansion of thymocytes. J. Immunol. 161:8 (1998), 3984–3991.
-
(1998)
J. Immunol.
, vol.161
, Issue.8
, pp. 3984-3991
-
-
Schilham, M.W.1
Wilson, A.2
-
158
-
-
77949956058
-
Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus
-
Schlenner, S.M., Madan, V., et al. Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus. Immunity 32:3 (2010), 426–436.
-
(2010)
Immunity
, vol.32
, Issue.3
, pp. 426-436
-
-
Schlenner, S.M.1
Madan, V.2
-
159
-
-
0031569111
-
TGF-beta differentially modulates epidermal growth factor-mediated increases in leukemia-inhibitory factor, IL-6, IL-1 alpha, and IL-1 beta in human thymic epithelial cells
-
Schluns, K., Cook, J., et al. TGF-beta differentially modulates epidermal growth factor-mediated increases in leukemia-inhibitory factor, IL-6, IL-1 alpha, and IL-1 beta in human thymic epithelial cells. J. Immunol. 158:6 (1997), 2704–2712.
-
(1997)
J. Immunol.
, vol.158
, Issue.6
, pp. 2704-2712
-
-
Schluns, K.1
Cook, J.2
-
160
-
-
0026053972
-
Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis
-
Schmid, P., Cox, D., et al. Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis. Development 111:1 (1991), 117–130.
-
(1991)
Development
, vol.111
, Issue.1
, pp. 117-130
-
-
Schmid, P.1
Cox, D.2
-
161
-
-
33645050124
-
T-cell development, doing it in a dish
-
Schmitt, T.M., Zuniga-Pflucker, J.C., T-cell development, doing it in a dish. Immunol. Rev. 209 (2006), 95–102.
-
(2006)
Immunol. Rev.
, vol.209
, pp. 95-102
-
-
Schmitt, T.M.1
Zuniga-Pflucker, J.C.2
-
162
-
-
33746894588
-
Conserved functions of ikaros in vertebrate lymphocyte development: genetic evidence for distinct larval and adult phases of T cell development and two lineages of B cells in zebrafish
-
Schorpp, M., Bialecki, M., et al. Conserved functions of ikaros in vertebrate lymphocyte development: genetic evidence for distinct larval and adult phases of T cell development and two lineages of B cells in zebrafish. J. Immunol. 177:4 (2006), 2463–2476.
-
(2006)
J. Immunol.
, vol.177
, Issue.4
, pp. 2463-2476
-
-
Schorpp, M.1
Bialecki, M.2
-
163
-
-
0036803182
-
A zebrafish orthologue (whnb) of the mouse nude gene is expressed in the epithelial compartment of the embryonic thymic rudiment
-
Schorpp, M., Leicht, M., et al. A zebrafish orthologue (whnb) of the mouse nude gene is expressed in the epithelial compartment of the embryonic thymic rudiment. Mech. Dev. 118:1–2 (2002), 179–185.
-
(2002)
Mech. Dev.
, vol.118
, Issue.1-2
, pp. 179-185
-
-
Schorpp, M.1
Leicht, M.2
-
164
-
-
33846902089
-
Selective thymus settling regulated by cytokine and chemokine receptors
-
Schwarz, B.A., Sambandam, A., et al. Selective thymus settling regulated by cytokine and chemokine receptors. J. Immunol. 178:4 (2007), 2008–2017.
-
(2007)
J. Immunol.
, vol.178
, Issue.4
, pp. 2008-2017
-
-
Schwarz, B.A.1
Sambandam, A.2
-
165
-
-
38949185052
-
Repression of the transcription factor Th-POK by runx complexes in cytotoxic T cell development
-
Setoguchi, R., Tachibana, M., et al. Repression of the transcription factor Th-POK by runx complexes in cytotoxic T cell development. Science 319:5864 (2008), 822–825.
-
(2008)
Science
, vol.319
, Issue.5864
, pp. 822-825
-
-
Setoguchi, R.1
Tachibana, M.2
-
166
-
-
54049118794
-
Maintenance of thymic epithelial phenotype requires extrinsic signals in mouse and zebrafish
-
Soza-Ried, C., Bleul, C.C., et al. Maintenance of thymic epithelial phenotype requires extrinsic signals in mouse and zebrafish. J. Immunol. 181:8 (2008), 5272–5277.
-
(2008)
J. Immunol.
, vol.181
, Issue.8
, pp. 5272-5277
-
-
Soza-Ried, C.1
Bleul, C.C.2
-
167
-
-
0037375686
-
Wnt signaling in the thymus
-
Staal, F.J., Clevers, H.C., Wnt signaling in the thymus. Curr. Opin. Immunol. 15:2 (2003), 204–208.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, Issue.2
, pp. 204-208
-
-
Staal, F.J.1
Clevers, H.C.2
-
168
-
-
48749101937
-
WNT signalling in the immune system: WNT is spreading its wings
-
Staal, F.J., Luis, T.C., et al. WNT signalling in the immune system: WNT is spreading its wings. Nat. Rev. Immunol. 8:8 (2008), 581–593.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, Issue.8
, pp. 581-593
-
-
Staal, F.J.1
Luis, T.C.2
-
169
-
-
0035134933
-
Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription
-
Staal, F.J.T., Meeldijk, J., et al. Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription. Eur. J. Immunol. 31:1 (2001), 285–293.
-
(2001)
Eur. J. Immunol.
, vol.31
, Issue.1
, pp. 285-293
-
-
Staal, F.J.T.1
Meeldijk, J.2
-
170
-
-
33748784324
-
Developmental genetic mechanisms of evolutionary tooth loss in cypriniform fishes
-
Stock, D.W., Jackman, W.R., et al. Developmental genetic mechanisms of evolutionary tooth loss in cypriniform fishes. Development 133:16 (2006), 3127–3137.
-
(2006)
Development
, vol.133
, Issue.16
, pp. 3127-3137
-
-
Stock, D.W.1
Jackman, W.R.2
-
171
-
-
0035881214
-
Hoxa3 and Pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis
-
Su, D., Hoxa3 and Pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis. Dev. Biol. 236:2 (2001), 316–329.
-
(2001)
Dev. Biol.
, vol.236
, Issue.2
, pp. 316-329
-
-
Su, D.1
-
172
-
-
0035881214
-
Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis
-
Su, D., Ellis, S., et al. Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis. Dev. Biol. 236:2 (2001), 316–329.
-
(2001)
Dev. Biol.
, vol.236
, Issue.2
, pp. 316-329
-
-
Su, D.1
Ellis, S.2
-
173
-
-
0034119902
-
Hoxa3 and pax1 transcription factors regulate the ability of fetal thymic epithelial cells to promote thymocyte development
-
Su, D.M., Manley, N.R., Hoxa3 and pax1 transcription factors regulate the ability of fetal thymic epithelial cells to promote thymocyte development. J. Immunol. 164:11 (2000), 5753–5760.
-
(2000)
J. Immunol.
, vol.164
, Issue.11
, pp. 5753-5760
-
-
Su, D.M.1
Manley, N.R.2
-
174
-
-
0027443753
-
Expression and function of the interleukin 7 receptor in murine lymphocytes
-
Sudo, T., Nishikawa, S., et al. Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc. Natl. Acad. Sci. USA 90:19 (1993), 9125–9129.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, Issue.19
, pp. 9125-9129
-
-
Sudo, T.1
Nishikawa, S.2
-
175
-
-
63849086285
-
An early decrease in Notch activation is required for human TCR-alpha beta lineage differentiation at the expense of TCR-gamma delta T cells
-
Taghon, T., Van de Walle, I., et al. An early decrease in Notch activation is required for human TCR-alpha beta lineage differentiation at the expense of TCR-gamma delta T cells. Blood 113:13 (2009), 2988–2998.
-
(2009)
Blood
, vol.113
, Issue.13
, pp. 2988-2998
-
-
Taghon, T.1
Van de Walle, I.2
-
176
-
-
30444454357
-
Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus
-
Taghon, T., Yui, M.A., et al. Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus. Immunity 24:1 (2006), 53–64.
-
(2006)
Immunity
, vol.24
, Issue.1
, pp. 53-64
-
-
Taghon, T.1
Yui, M.A.2
-
177
-
-
34250217913
-
Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3
-
Taghon, T., Yui, M.A., et al. Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3. Nat. Immunol. 8:8 (2007), 845–855.
-
(2007)
Nat. Immunol.
, vol.8
, Issue.8
, pp. 845-855
-
-
Taghon, T.1
Yui, M.A.2
-
178
-
-
0035170433
-
Murine Schnurri-2 is required for positive selection of thymocytes
-
Takagi, T., Harada, J., et al. Murine Schnurri-2 is required for positive selection of thymocytes. Nat. Immunol. 2:11 (2001), 1048–1053.
-
(2001)
Nat. Immunol.
, vol.2
, Issue.11
, pp. 1048-1053
-
-
Takagi, T.1
Harada, J.2
-
179
-
-
33644845679
-
Journey through the thymus: stromal guides for T-cell development and selection
-
Takahama, Y., Journey through the thymus: stromal guides for T-cell development and selection. Nat. Rev. Immunol. 6:2 (2006), 127–135.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, Issue.2
, pp. 127-135
-
-
Takahama, Y.1
-
180
-
-
0035881544
-
E2A and HEB activate the pre-TCR alpha promoter during immature T cell development
-
Takeuchi, A., Yamasaki, S., et al. E2A and HEB activate the pre-TCR alpha promoter during immature T cell development. J. Immunol. 167:4 (2001), 2157–2163.
-
(2001)
J. Immunol.
, vol.167
, Issue.4
, pp. 2157-2163
-
-
Takeuchi, A.1
Yamasaki, S.2
-
181
-
-
33845994697
-
T-lymphoid, megakaryocyte, and granulocyte development are sensitive to decreases in CBFbeta dosage
-
Talebian, L., Li, Z., et al. T-lymphoid, megakaryocyte, and granulocyte development are sensitive to decreases in CBFbeta dosage. Blood 109:1 (2007), 11–21.
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 11-21
-
-
Talebian, L.1
Li, Z.2
-
182
-
-
0037381403
-
Regulation of B cell development by Notch/RBP-J signaling
-
Tanigaki, K., Kuroda, K., et al. Regulation of B cell development by Notch/RBP-J signaling. Semin. Immunol. 15:2 (2003), 113–119.
-
(2003)
Semin. Immunol.
, vol.15
, Issue.2
, pp. 113-119
-
-
Tanigaki, K.1
Kuroda, K.2
-
183
-
-
2442522357
-
Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
-
Tanigaki, K., Tsuji, M., et al. Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity 20:5 (2004), 611–622.
-
(2004)
Immunity
, vol.20
, Issue.5
, pp. 611-622
-
-
Tanigaki, K.1
Tsuji, M.2
-
184
-
-
18744398397
-
Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
-
Taniuchi, I., Osato, M., et al. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 111:5 (2002), 621–633.
-
(2002)
Cell
, vol.111
, Issue.5
, pp. 621-633
-
-
Taniuchi, I.1
Osato, M.2
-
185
-
-
33645834949
-
Evidence for a functional second thymus in mice
-
Terszowski, G., Evidence for a functional second thymus in mice. Science 312:5771 (2006), 284–287.
-
(2006)
Science
, vol.312
, Issue.5771
, pp. 284-287
-
-
Terszowski, G.1
-
186
-
-
79952449676
-
Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish
-
Toda, H., Saito, Y., et al. Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish. Dev. Comp. Immunol. 35:6 (2011), 650–660.
-
(2011)
Dev. Comp. Immunol.
, vol.35
, Issue.6
, pp. 650-660
-
-
Toda, H.1
Saito, Y.2
-
187
-
-
0038805207
-
Regulation of pT alpha gene expression by a dosage of E2A, HEB, and SCL
-
Tremblay, M., Herblot, S., et al. Regulation of pT alpha gene expression by a dosage of E2A, HEB, and SCL. J. Biol. Chem. 278:15 (2003), 12680–12687.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.15
, pp. 12680-12687
-
-
Tremblay, M.1
Herblot, S.2
-
188
-
-
0345689338
-
BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis
-
Tsai, P.T., Lee, R.A., et al. BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis. Blood 102:12 (2003), 3947–3953.
-
(2003)
Blood
, vol.102
, Issue.12
, pp. 3947-3953
-
-
Tsai, P.T.1
Lee, R.A.2
-
189
-
-
0037384858
-
The role of morphogens in T-cell development
-
Varas, A., The role of morphogens in T-cell development. Trends Immunol. 24:4 (2003), 197–206.
-
(2003)
Trends Immunol.
, vol.24
, Issue.4
, pp. 197-206
-
-
Varas, A.1
-
190
-
-
74849135750
-
Interplay between BMP4 and IL-7 in human intrathymic precursor cells
-
Varas, A., Sacedon, R., et al. Interplay between BMP4 and IL-7 in human intrathymic precursor cells. Cell Cycle 8:24 (2009), 4119–4126.
-
(2009)
Cell Cycle
, vol.8
, Issue.24
, pp. 4119-4126
-
-
Varas, A.1
Sacedon, R.2
-
191
-
-
0028985161
-
An HMG-box-containing T-cell factor required for thymocyte differentiation
-
Verbeek, S., Izon, D., et al. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature 374:6517 (1995), 70–74.
-
(1995)
Nature
, vol.374
, Issue.6517
, pp. 70-74
-
-
Verbeek, S.1
Izon, D.2
-
192
-
-
77955985384
-
Molecular and cellular basis of T cell lineage commitment
-
Vicente, R., Swainson, L., et al. Molecular and cellular basis of T cell lineage commitment. Semin. Immunol. 22:5 (2010), 270–275.
-
(2010)
Semin. Immunol.
, vol.22
, Issue.5
, pp. 270-275
-
-
Vicente, R.1
Swainson, L.2
-
193
-
-
42049089318
-
Adult T-cell progenitors retain myeloid potential
-
Wada, H., Masuda, K., et al. Adult T-cell progenitors retain myeloid potential. Nature 452:7188 (2008), 768–772.
-
(2008)
Nature
, vol.452
, Issue.7188
, pp. 768-772
-
-
Wada, H.1
Masuda, K.2
-
194
-
-
0030069119
-
Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation
-
Wallin, J., Eibel, H., et al. Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation. Development 122:1 (1996), 23–30.
-
(1996)
Development
, vol.122
, Issue.1
, pp. 23-30
-
-
Wallin, J.1
Eibel, H.2
-
195
-
-
70349247895
-
CD4-CD8 lineage differentiation: Thpok-ing into the nucleus
-
Wang, L., Bosselut, R., CD4-CD8 lineage differentiation: Thpok-ing into the nucleus. J. Immunol. 183:5 (2009), 2903–2910.
-
(2009)
J. Immunol.
, vol.183
, Issue.5
, pp. 2903-2910
-
-
Wang, L.1
Bosselut, R.2
-
196
-
-
79961140554
-
A critical role for TCF-1 in T-lineage specification and differentiation
-
Weber, B.N., Chi, A.W.-S., et al. A critical role for TCF-1 in T-lineage specification and differentiation. Nature 476:7358 (2011), 63–68.
-
(2011)
Nature
, vol.476
, Issue.7358
, pp. 63-68
-
-
Weber, B.N.1
Chi, A.W.-S.2
-
197
-
-
33644772155
-
Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules
-
Weerkamp, F., Baert, M.R.M., et al. Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules. Proc. Natl. Acad. Sci. USA 103:9 (2006), 3322–3326.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, Issue.9
, pp. 3322-3326
-
-
Weerkamp, F.1
Baert, M.R.M.2
-
198
-
-
80051885764
-
Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types
-
Wei, G., Abraham, B.J., et al. Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity 35:2 (2011), 299–311.
-
(2011)
Immunity
, vol.35
, Issue.2
, pp. 299-311
-
-
Wei, G.1
Abraham, B.J.2
-
199
-
-
85190493713
-
-
Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell 43 (3 Pt 2), 567–581.
-
Wharton, K.A., Johansen, K.M., et al., 1985. Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell 43 (3 Pt 2), 567–581.
-
(1985)
-
-
Wharton, K.A.1
Johansen, K.M.2
-
200
-
-
0032902009
-
Early hematopoiesis and developing lymphoid organs in the zebrafish
-
Willett, C.E., Cortes, A., et al. Early hematopoiesis and developing lymphoid organs in the zebrafish. Dev. Dyn. 214:4 (1999), 323–336.
-
(1999)
Dev. Dyn.
, vol.214
, Issue.4
, pp. 323-336
-
-
Willett, C.E.1
Cortes, A.2
-
201
-
-
0035477668
-
Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus
-
Wilson, A., MacDonald, H.R., et al. Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. J. Exp. Med. 194:7 (2001), 1003–1012.
-
(2001)
J. Exp. Med.
, vol.194
, Issue.7
, pp. 1003-1012
-
-
Wilson, A.1
MacDonald, H.R.2
-
202
-
-
34247627897
-
E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression
-
Wojciechowski, J., Lai, A., et al. E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression. J. Immunol. 178:9 (2007), 5717–5726.
-
(2007)
J. Immunol.
, vol.178
, Issue.9
, pp. 5717-5726
-
-
Wojciechowski, J.1
Lai, A.2
-
203
-
-
0036070308
-
Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes
-
Wolfer, A., Wilson, A., et al. Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. Immunity 16:6 (2002), 869–879.
-
(2002)
Immunity
, vol.16
, Issue.6
, pp. 869-879
-
-
Wolfer, A.1
Wilson, A.2
-
204
-
-
27644554787
-
Timed mutation and cell-fate mapping reveal reiterated roles of Tbx1 during embryogenesis, and a crucial function during segmentation of the pharyngeal system via regulation of endoderm expansion
-
Xu, H., Cerrato, F., et al. Timed mutation and cell-fate mapping reveal reiterated roles of Tbx1 during embryogenesis, and a crucial function during segmentation of the pharyngeal system via regulation of endoderm expansion. Development 132:19 (2005), 4387–4395.
-
(2005)
Development
, vol.132
, Issue.19
, pp. 4387-4395
-
-
Xu, H.1
Cerrato, F.2
-
205
-
-
0036333792
-
Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid
-
Xu, P.X., Zheng, W.M., et al. Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid. Development 129:13 (2002), 3033–3044.
-
(2002)
Development
, vol.129
, Issue.13
, pp. 3033-3044
-
-
Xu, P.X.1
Zheng, W.M.2
-
206
-
-
0346121607
-
Deletion of beta-catenin impairs T cell development
-
Xu, Y., Banerjee, D., et al. Deletion of beta-catenin impairs T cell development. Nat. Immunol. 4:12 (2003), 1177–1182.
-
(2003)
Nat. Immunol.
, vol.4
, Issue.12
, pp. 1177-1182
-
-
Xu, Y.1
Banerjee, D.2
-
207
-
-
0037439240
-
Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer
-
Yamagishi, H., Maeda, J., et al. Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev. 17:2 (2003), 269–281.
-
(2003)
Genes Dev.
, vol.17
, Issue.2
, pp. 269-281
-
-
Yamagishi, H.1
Maeda, J.2
-
208
-
-
67650588402
-
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A
-
Yashiro-Ohtani, Y., He, Y., et al. Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A. Genes Dev. 23:14 (2009), 1665–1676.
-
(2009)
Genes Dev.
, vol.23
, Issue.14
, pp. 1665-1676
-
-
Yashiro-Ohtani, Y.1
He, Y.2
-
209
-
-
77955980546
-
Notch regulation of early thymocyte development
-
Yashiro-Ohtani, Y., Ohtani, T., et al. Notch regulation of early thymocyte development. Semin. Immunol. 22:5 (2010), 261–269.
-
(2010)
Semin. Immunol.
, vol.22
, Issue.5
, pp. 261-269
-
-
Yashiro-Ohtani, Y.1
Ohtani, T.2
-
210
-
-
0035652459
-
The IL-7 receptor controls the accessibility of the TCRgamma locus by Stat5 and histone acetylation
-
Ye, S.K., Agata, Y., et al. The IL-7 receptor controls the accessibility of the TCRgamma locus by Stat5 and histone acetylation. Immunity 15:5 (2001), 813–823.
-
(2001)
Immunity
, vol.15
, Issue.5
, pp. 813-823
-
-
Ye, S.K.1
Agata, Y.2
-
211
-
-
33645109285
-
Early hematopoietic lineage restrictions directed by Ikaros
-
Yoshida, T., Ng, S.Y., et al. Early hematopoietic lineage restrictions directed by Ikaros. Nat. Immunol. 7:4 (2006), 382–391.
-
(2006)
Nat. Immunol.
, vol.7
, Issue.4
, pp. 382-391
-
-
Yoshida, T.1
Ng, S.Y.2
-
212
-
-
34247105894
-
β-Catenin regulates positive selection of thymocytes but not lineage commitment
-
Yu, Q., Sen, J.M., β-Catenin regulates positive selection of thymocytes but not lineage commitment. J. Immunol. 178:8 (2007), 5028–5034.
-
(2007)
J. Immunol.
, vol.178
, Issue.8
, pp. 5028-5034
-
-
Yu, Q.1
Sen, J.M.2
-
213
-
-
77953959985
-
TCF1 and beta-catenin regulate T cell development and function
-
Yu, Q., Sharma, A., et al. TCF1 and beta-catenin regulate T cell development and function. Immunol. Res. 47:1–3 (2010), 45–55.
-
(2010)
Immunol. Res.
, vol.47
, Issue.1-3
, pp. 45-55
-
-
Yu, Q.1
Sharma, A.2
-
214
-
-
34250851638
-
Beta-catenin expression enhances IL-7 receptor signaling in thymocytes during positive selection
-
Yu, Q., Xu, M., et al. Beta-catenin expression enhances IL-7 receptor signaling in thymocytes during positive selection. J. Immunol. 179:1 (2007), 126–131.
-
(2007)
J. Immunol.
, vol.179
, Issue.1
, pp. 126-131
-
-
Yu, Q.1
Xu, M.2
-
215
-
-
73349107484
-
The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus
-
Zamisch, M., Tian, L., et al. The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus. J. Exp. Med. 206:12 (2009), 2685–2699.
-
(2009)
J. Exp. Med.
, vol.206
, Issue.12
, pp. 2685-2699
-
-
Zamisch, M.1
Tian, L.2
-
216
-
-
77950407764
-
CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus
-
Zlotoff, D.A., Sambandam, A., et al. CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus. Blood 115:10 (2010), 1897–1905.
-
(2010)
Blood
, vol.115
, Issue.10
, pp. 1897-1905
-
-
Zlotoff, D.A.1
Sambandam, A.2
-
217
-
-
33646185393
-
Patterning of the third pharyngeal pouch into thymus/parathyroid by Six and Eya1
-
Zou, D., Silvius, D., et al. Patterning of the third pharyngeal pouch into thymus/parathyroid by Six and Eya1. Dev. Biol. 293:2 (2006), 499–512.
-
(2006)
Dev. Biol.
, vol.293
, Issue.2
, pp. 499-512
-
-
Zou, D.1
Silvius, D.2
|