-
1
-
-
0032784934
-
Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage
-
Anderson, M.K., G. Hernandez-Hoyos, R.A. Diamond, and E.V. Rothenberg. 1999. Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage. Development. 126: 3131-3148.
-
(1999)
Development
, vol.126
, pp. 3131-3148
-
-
Anderson, M.K.1
Hernandez-Hoyos, G.2
Diamond, R.A.3
Rothenberg, E.V.4
-
2
-
-
2942627442
-
Transcriptional regulation of human CD5: Important role of Ets transcription factors in CD5 expression in T cells
-
Arman, M., J. Calvo, M.E. Trojanowska, P.N. Cockerill, M. Santana, M. López-Cabrera, J. Vives, and F. Lozano. 2004. Transcriptional regulation of human CD5: important role of Ets transcription factors in CD5 expression in T cells. J. Immunol. 172: 7519-7529.
-
(2004)
J. Immunol
, vol.172
, pp. 7519-7529
-
-
Arman, M.1
Calvo, J.2
Trojanowska, M.E.3
Cockerill, P.N.4
Santana, M.5
López-Cabrera, M.6
Vives, J.7
Lozano, F.8
-
3
-
-
0031897801
-
Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements
-
doi:10.1046/j.1440-1711 .1998.00709.x
-
Barnden, M.J., J. Allison, W.R. Heath, and F.R. Carbone. 1998. Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76: 34-40. doi:10.1046/j.1440-1711 .1998.00709.x
-
(1998)
Immunol. Cell Biol
, vol.76
, pp. 34-40
-
-
Barnden, M.J.1
Allison, J.2
Heath, W.R.3
Carbone, F.R.4
-
4
-
-
0034012933
-
-
Barton, K., and G. Nucifora. 2000. AML1 haploinsufficiency, gene dosage, and the predisposition to acute leukemia. Bioessays. 22: 214-218. doi:10.1002/ (SICI)1521-1878(200003)22:3〈214::AID-BIES2〉3.0.CO;2-I
-
Barton, K., and G. Nucifora. 2000. AML1 haploinsufficiency, gene dosage, and the predisposition to acute leukemia. Bioessays. 22: 214-218. doi:10.1002/ (SICI)1521-1878(200003)22:3〈214::AID-BIES2〉3.0.CO;2-I
-
-
-
-
5
-
-
0032191918
-
The Ets-1 transcription factor is required for the development of natural killer cells in mice
-
doi:10.1016/S1074-7613(00)80638-X
-
Barton, K., N. Muthusamy, C. Fischer, C.N. Ting, T.L. Walunas, L.L. Lanier, and J.M. Leiden. 1998. The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity. 9: 555-563. doi:10.1016/S1074-7613(00)80638-X
-
(1998)
Immunity
, vol.9
, pp. 555-563
-
-
Barton, K.1
Muthusamy, N.2
Fischer, C.3
Ting, C.N.4
Walunas, T.L.5
Lanier, L.L.6
Leiden, J.M.7
-
6
-
-
0028880729
-
Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene
-
doi:10.1038/377635a0
-
Bories, J.C., D.M. Willerford, D. Grévin, L. Davidson, A. Camus, P. Martin, D. Stéhelin, and F.W. Alt. 1995. Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene. Nature. 377: 635-638. doi:10.1038/377635a0
-
(1995)
Nature
, vol.377
, pp. 635-638
-
-
Bories, J.C.1
Willerford, D.M.2
Grévin, D.3
Davidson, L.4
Camus, A.5
Martin, P.6
Stéhelin, D.7
Alt, F.W.8
-
7
-
-
3142769748
-
CD4/CD8-lineage differentiation in the thymus: From nuclear effectors to membrane signals
-
doi:10.1038/nri1392
-
Bosselut, R. 2004. CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals. Nat. Rev. Immunol. 4: 529-540. doi:10.1038/nri1392
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 529-540
-
-
Bosselut, R.1
-
8
-
-
0033696599
-
Coreceptor reversal in the thymus: Signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells
-
doi:10.1016/S1074-7613(00)00008-X
-
Brugnera, E., A. Bhandoola, R. Cibotti, Q. Yu, T.I. Guinter, Y. Yamashita, S.O. Sharrow, and A. Singer. 2000. Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells. Immunity. 13: 59-71. doi:10.1016/S1074-7613(00)00008-X
-
(2000)
Immunity
, vol.13
, pp. 59-71
-
-
Brugnera, E.1
Bhandoola, A.2
Cibotti, R.3
Yu, Q.4
Guinter, T.I.5
Yamashita, Y.6
Sharrow, S.O.7
Singer, A.8
-
9
-
-
33745867628
-
Impaired generation of CD8+ thymocytes in Ets-1-deficient mice
-
Clements, J.L., S.A. John, and L.A. Garrett-Sinha. 2006. Impaired generation of CD8+ thymocytes in Ets-1-deficient mice. J. Immunol. 177: 905-912.
-
(2006)
J. Immunol
, vol.177
, pp. 905-912
-
-
Clements, J.L.1
John, S.A.2
Garrett-Sinha, L.A.3
-
10
-
-
60549090859
-
Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs
-
doi:10.1084/jem.20081242
-
Cruz-Guilloty, F., M.E. Pipkin, I.M. Djuretic, D. Levanon, J. Lotem, M.G. Lichtenheld, Y. Groner, and A. Rao. 2009. Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. J. Exp. Med. 206: 51-59. doi:10.1084/jem.20081242
-
(2009)
J. Exp. Med
, vol.206
, pp. 51-59
-
-
Cruz-Guilloty, F.1
Pipkin, M.E.2
Djuretic, I.M.3
Levanon, D.4
Lotem, J.5
Lichtenheld, M.G.6
Groner, Y.7
Rao, A.8
-
11
-
-
33846489173
-
Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells
-
doi:10.1038/ni1424
-
Djuretic, I.M., D. Levanon, V. Negreanu, Y. Groner, A. Rao, and K.M. Ansel. 2007. Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. Nat. Immunol. 8: 145-153. doi:10.1038/ni1424
-
(2007)
Nat. Immunol
, vol.8
, pp. 145-153
-
-
Djuretic, I.M.1
Levanon, D.2
Negreanu, V.3
Groner, Y.4
Rao, A.5
Ansel, K.M.6
-
12
-
-
52549101132
-
ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage
-
doi:10.1038/ni.1652
-
Egawa, T., and D.R. Littman. 2008. ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage. Nat. Immunol. 9: 1131-1139. doi:10.1038/ni.1652
-
(2008)
Nat. Immunol
, vol.9
, pp. 1131-1139
-
-
Egawa, T.1
Littman, D.R.2
-
13
-
-
34547744867
-
The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells
-
doi:10.1084/jem.20070133
-
Egawa, T., R.E. Tillman, Y. Naoe, I. Taniuchi, and D.R. Littman. 2007. The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells. J. Exp. Med. 204: 1945-1957. doi:10.1084/jem.20070133
-
(2007)
J. Exp. Med
, vol.204
, pp. 1945-1957
-
-
Egawa, T.1
Tillman, R.E.2
Naoe, Y.3
Taniuchi, I.4
Littman, D.R.5
-
14
-
-
0141920621
-
Morpholino antisense oligonucleotide-mediated gene knockdown during thymocyte development reveals role for Runx3 transcription factor in CD4 silencing during development of CD4-/CD8+ thymocytes
-
Ehlers, M., K. Laule-Kilian, M. Petter, C.J. Aldrian, B. Grueter, A. Würch, N. Yoshida, T. Watanabe, M. Satake, and V. Steimle. 2003. Morpholino antisense oligonucleotide-mediated gene knockdown during thymocyte development reveals role for Runx3 transcription factor in CD4 silencing during development of CD4-/CD8+ thymocytes. J. Immunol. 171: 3594-3604.
-
(2003)
J. Immunol
, vol.171
, pp. 3594-3604
-
-
Ehlers, M.1
Laule-Kilian, K.2
Petter, M.3
Aldrian, C.J.4
Grueter, B.5
Würch, A.6
Yoshida, N.7
Watanabe, T.8
Satake, M.9
Steimle, V.10
-
15
-
-
0031951663
-
ETS-core binding factor: A common composite motif in antigen receptor gene enhancers
-
Erman, B., M. Cortes, B.S. Nikolajczyk, N.A. Speck, and R. Sen. 1998. ETS-core binding factor: a common composite motif in antigen receptor gene enhancers. Mol. Cell. Biol. 18: 1322-1330.
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 1322-1330
-
-
Erman, B.1
Cortes, M.2
Nikolajczyk, B.S.3
Speck, N.A.4
Sen, R.5
-
16
-
-
8144221076
-
The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus
-
doi:10.1073/pnas.0405546101
-
Eyquem, S., K. Chemin, M. Fasseu, and J.C. Bories. 2004. The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus. Proc. Natl. Acad. Sci. USA. 101: 15712-15717. doi:10.1073/pnas.0405546101
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15712-15717
-
-
Eyquem, S.1
Chemin, K.2
Fasseu, M.3
Bories, J.C.4
-
17
-
-
0024566240
-
Molecular and cellular events of T cell development
-
doi:10.1016/S0065-2776(08) 60643-4
-
Fowlkes, B.J., and D.M. Pardoll. 1989. Molecular and cellular events of T cell development. Adv. Immunol. 44: 207-264. doi:10.1016/S0065-2776(08) 60643-4
-
(1989)
Adv. Immunol
, vol.44
, pp. 207-264
-
-
Fowlkes, B.J.1
Pardoll, D.M.2
-
18
-
-
0033988443
-
Auto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2
-
doi:10.1128/MCB.20.1.81-90.2000
-
Goetz, T.L., T.L. Gu, N.A. Speck, and B.J. Graves. 2000. Auto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2. Mol. Cell. Biol. 20: 81-90. doi:10.1128/MCB.20.1.81-90.2000
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 81-90
-
-
Goetz, T.L.1
Gu, T.L.2
Speck, N.A.3
Graves, B.J.4
-
19
-
-
14244251950
-
Ets-1, a functional cofactor of T-bet, is essential for Th1 infl ammatory responses
-
doi:10.1084/jem.20041330
-
Grenningloh, R., B.Y. Kang, and I.C. Ho. 2005. Ets-1, a functional cofactor of T-bet, is essential for Th1 infl ammatory responses. J. Exp. Med. 201: 615-626. doi:10.1084/jem.20041330
-
(2005)
J. Exp. Med
, vol.201
, pp. 615-626
-
-
Grenningloh, R.1
Kang, B.Y.2
Ho, I.C.3
-
20
-
-
49649104975
-
Role of Ets-1 phosphorylation in the effector function of Th cells
-
doi:10.1002/eji.200738112
-
Grenningloh, R., S.C. Miaw, J. Moisan, B.J. Graves, and I.C. Ho. 2008. Role of Ets-1 phosphorylation in the effector function of Th cells. Eur. J. Immunol. 38: 1700-1705. doi:10.1002/eji.200738112
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 1700-1705
-
-
Grenningloh, R.1
Miaw, S.C.2
Moisan, J.3
Graves, B.J.4
Ho, I.C.5
-
21
-
-
22544451206
-
Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells
-
Grueter, B., M. Petter, T. Egawa, K. Laule-Kilian, C.J. Aldrian, A. Wuerch, Y. Ludwig, H. Fukuyama, H. Wardemann, R. Waldschuetz, et al. 2005. Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells. J. Immunol. 175: 1694-1705.
-
(2005)
J. Immunol
, vol.175
, pp. 1694-1705
-
-
Grueter, B.1
Petter, M.2
Egawa, T.3
Laule-Kilian, K.4
Aldrian, C.J.5
Wuerch, A.6
Ludwig, Y.7
Fukuyama, H.8
Wardemann, H.9
Waldschuetz, R.10
-
22
-
-
0033988402
-
Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1)
-
doi:10.1128/MCB.20.1.91-103.2000
-
Gu, T.L., T.L. Goetz, B.J. Graves, and N.A. Speck. 2000. Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1). Mol. Cell. Biol. 20: 91 -103. doi:10.1128/MCB.20.1.91-103.2000
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 91-103
-
-
Gu, T.L.1
Goetz, T.L.2
Graves, B.J.3
Speck, N.A.4
-
23
-
-
14544288635
-
The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
-
doi:10.1038/nature03338
-
He, X., X. He, V.P. Dave, Y. Zhang, X. Hua, E. Nicolas, W. Xu, B.A. Roe, and D.J. Kappes. 2005. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature. 433: 826-833. doi:10.1038/nature03338
-
(2005)
Nature
, vol.433
, pp. 826-833
-
-
He, X.1
He, X.2
Dave, V.P.3
Zhang, Y.4
Hua, X.5
Nicolas, E.6
Xu, W.7
Roe, B.A.8
Kappes, D.J.9
-
24
-
-
0038783583
-
GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation
-
doi:10.1016/ S1074-7613(03)00176-6
-
Hernández-Hoyos, G., M.K. Anderson, C. Wang, E.V. Rothenberg, and J. Alberola-Ila. 2003. GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation. Immunity. 19: 83-94. doi:10.1016/ S1074-7613(03)00176-6
-
(2003)
Immunity
, vol.19
, pp. 83-94
-
-
Hernández-Hoyos, G.1
Anderson, M.K.2
Wang, C.3
Rothenberg, E.V.4
Alberola-Ila, J.5
-
25
-
-
34247621213
-
Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice
-
doi:10.1128/MCB.01871-06
-
Higuchi, T., F.O. Bartel, M. Masuya, T. Deguchi, K.W. Henderson, R. Li, R.C. Muise-Helmericks, M.J. Kern, D.K. Watson, and D.D. Spyropoulos. 2007. Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice. Mol. Cell. Biol. 27: 3353-3366. doi:10.1128/MCB.01871-06
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 3353-3366
-
-
Higuchi, T.1
Bartel, F.O.2
Masuya, M.3
Deguchi, T.4
Henderson, K.W.5
Li, R.6
Muise-Helmericks, R.C.7
Kern, M.J.8
Watson, D.K.9
Spyropoulos, D.D.10
-
26
-
-
0025241156
-
Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer
-
doi:10.1126/ science.2237431
-
Ho, I.C., N.K. Bhat, L.R. Gottschalk, T. Lindsten, C.B. Thompson, T.S. Papas, and J.M. Leiden. 1990. Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer. Science. 250: 814-818. doi:10.1126/ science.2237431
-
(1990)
Science
, vol.250
, pp. 814-818
-
-
Ho, I.C.1
Bhat, N.K.2
Gottschalk, L.R.3
Lindsten, T.4
Thompson, C.B.5
Papas, T.S.6
Leiden, J.M.7
-
27
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
doi:10.1016/0092-8674(94)90169-4
-
Hogquist, K.A., S.C. Jameson, W.R. Heath, J.L. Howard, M.J. Bevan, and F.R. Carbone. 1994. T cell receptor antagonist peptides induce positive selection. Cell. 76: 17-27. doi:10.1016/0092-8674(94)90169-4
-
(1994)
Cell
, vol.76
, pp. 17-27
-
-
Hogquist, K.A.1
Jameson, S.C.2
Heath, W.R.3
Howard, J.L.4
Bevan, M.J.5
Carbone, F.R.6
-
28
-
-
34547641224
-
Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family
-
doi:10.1101/gad .1561707
-
Hollenhorst, P.C., A.A. Shah, C. Hopkins, and B.J. Graves. 2007. Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev. 21: 1882-1894. doi:10.1101/gad .1561707
-
(2007)
Genes Dev
, vol.21
, pp. 1882-1894
-
-
Hollenhorst, P.C.1
Shah, A.A.2
Hopkins, C.3
Graves, B.J.4
-
29
-
-
33847153126
-
Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation
-
doi:10.1084/jem .20061982
-
Jenkinson, S.R., A.M. Intlekofer, G. Sun, L. Feigenbaum, S.L. Reiner, and R. Bosselut. 2007. Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation. J. Exp. Med. 204: 267-272. doi:10.1084/jem .20061982
-
(2007)
J. Exp. Med
, vol.204
, pp. 267-272
-
-
Jenkinson, S.R.1
Intlekofer, A.M.2
Sun, G.3
Feigenbaum, L.4
Reiner, S.L.5
Bosselut, R.6
-
30
-
-
0033559972
-
Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains
-
doi:10.1093/emboj/18.6.1609
-
Kim, W.Y., M. Sieweke, E. Ogawa, H.J. Wee, U. Englmeier, T. Graf, and Y. Ito. 1999. Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains. EMBO J. 18: 1609-1620. doi:10.1093/emboj/18.6.1609
-
(1999)
EMBO J
, vol.18
, pp. 1609-1620
-
-
Kim, W.Y.1
Sieweke, M.2
Ogawa, E.3
Wee, H.J.4
Englmeier, U.5
Graf, T.6
Ito, Y.7
-
31
-
-
0036885036
-
Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation
-
doi:10.1038/nri952
-
Kioussis, D., and W. Ellmeier. 2002. Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation. Nat. Rev. Immunol. 2: 909-919. doi:10.1038/nri952
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 909-919
-
-
Kioussis, D.1
Ellmeier, W.2
-
32
-
-
0033526862
-
Several different cell surface molecules control negative selection of medullary thymocytes
-
doi:10.1084/jem.190.1.65
-
Kishimoto, H., and J. Sprent. 1999. Several different cell surface molecules control negative selection of medullary thymocytes. J. Exp. Med. 190: 65-73. doi:10.1084/jem.190.1.65
-
(1999)
J. Exp. Med
, vol.190
, pp. 65-73
-
-
Kishimoto, H.1
Sprent, J.2
-
33
-
-
0032578456
-
Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment
-
doi:10.1073/pnas.95.20.11822
-
Klug, D.B., C. Carter, E. Crouch, D. Roop, C.J. Conti, and E.R. Richie. 1998. Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment. Proc. Natl. Acad. Sci. USA. 95: 11822-11827. doi:10.1073/pnas.95.20.11822
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11822-11827
-
-
Klug, D.B.1
Carter, C.2
Crouch, E.3
Roop, D.4
Conti, C.J.5
Richie, E.R.6
-
34
-
-
20044383185
-
Overexpression of the Runx3 transcription factor increases the proportion of mature thymocytes of the CD8 single-positive lineage
-
Kohu, K., T. Sato, S. Ohno, K. Hayashi, R. Uchino, N. Abe, M. Nakazato, N. Yoshida, T. Kikuchi, Y. Iwakura, et al. 2005. Overexpression of the Runx3 transcription factor increases the proportion of mature thymocytes of the CD8 single-positive lineage. J. Immunol. 174: 2627-2636.
-
(2005)
J. Immunol
, vol.174
, pp. 2627-2636
-
-
Kohu, K.1
Sato, T.2
Ohno, S.3
Hayashi, K.4
Uchino, R.5
Abe, N.6
Nakazato, M.7
Yoshida, N.8
Kikuchi, T.9
Iwakura, Y.10
-
35
-
-
1542377327
-
Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo
-
doi:10.1038/ ni1040
-
Liu, X., and R. Bosselut. 2004. Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo. Nat. Immunol. 5: 280-288. doi:10.1038/ ni1040
-
(2004)
Nat. Immunol
, vol.5
, pp. 280-288
-
-
Liu, X.1
Bosselut, R.2
-
36
-
-
0037415559
-
Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection
-
doi:10.1084/jem.20021698
-
Liu, X., A. Adams, K.F. Wildt, B. Aronow, L. Feigenbaum, and R. Bosselut. 2003. Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection. J. Exp. Med. 197: 363-373. doi:10.1084/jem.20021698
-
(2003)
J. Exp. Med
, vol.197
, pp. 363-373
-
-
Liu, X.1
Adams, A.2
Wildt, K.F.3
Aronow, B.4
Feigenbaum, L.5
Bosselut, R.6
-
37
-
-
52549124338
-
Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate
-
doi:10.1038/ni.1650
-
Muroi, S., Y. Naoe, C. Miyamoto, K. Akiyama, T. Ikawa, K. Masuda, H. Kawamoto, and I. Taniuchi. 2008. Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate. Nat. Immunol. 9: 1113-1121. doi:10.1038/ni.1650
-
(2008)
Nat. Immunol
, vol.9
, pp. 1113-1121
-
-
Muroi, S.1
Naoe, Y.2
Miyamoto, C.3
Akiyama, K.4
Ikawa, T.5
Masuda, K.6
Kawamoto, H.7
Taniuchi, I.8
-
38
-
-
0028864666
-
Defective activation and survival of T cells lacking the Ets-1 transcription factor
-
doi:10.1038/377639a0
-
Muthusamy, N., K. Barton, and J.M. Leiden. 1995. Defective activation and survival of T cells lacking the Ets-1 transcription factor. Nature. 377: 639-642. doi:10.1038/377639a0
-
(1995)
Nature
, vol.377
, pp. 639-642
-
-
Muthusamy, N.1
Barton, K.2
Leiden, J.M.3
-
39
-
-
34547727747
-
Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer
-
doi:10.1084/jem.20062456
-
Naoe, Y., R. Setoguchi, K. Akiyama, S. Muroi, M. Kuroda, F. Hatam, D.R. Littman, and I. Taniuchi. 2007. Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer. J. Exp. Med. 204: 1749-1755. doi:10.1084/jem.20062456
-
(2007)
J. Exp. Med
, vol.204
, pp. 1749-1755
-
-
Naoe, Y.1
Setoguchi, R.2
Akiyama, K.3
Muroi, S.4
Kuroda, M.5
Hatam, F.6
Littman, D.R.7
Taniuchi, I.8
-
40
-
-
0348110327
-
Critical roles for transcription factor GATA-3 in thymocyte development
-
doi:10.1016/S1074-7613(03)00328-5
-
Pai, S.Y., M.L. Truitt, C.N. Ting, J.M. Leiden, L.H. Glimcher, and I.C. Ho. 2003. Critical roles for transcription factor GATA-3 in thymocyte development. Immunity. 19: 863-875. doi:10.1016/S1074-7613(03)00328-5
-
(2003)
Immunity
, vol.19
, pp. 863-875
-
-
Pai, S.Y.1
Truitt, M.L.2
Ting, C.N.3
Leiden, J.M.4
Glimcher, L.H.5
Ho, I.C.6
-
41
-
-
0024307348
-
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
-
doi:10.1038/342559a0
-
Pircher, H., K. Bürki, R. Lang, H. Hengartner, and R.M. Zinkernagel. 1989. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature. 342: 559-561. doi:10.1038/342559a0
-
(1989)
Nature
, vol.342
, pp. 559-561
-
-
Pircher, H.1
Bürki, K.2
Lang, R.3
Hengartner, H.4
Zinkernagel, R.M.5
-
42
-
-
0025228880
-
Identification of a Ets1 variant protein unaffected in its chromatin and in vitro DNA binding capacities by T cell antigen receptor triggering and intracellular calcium rises
-
Pognonec, P., K.E. Boulukos, R. Bosselut, C. Boyer, A.M. Schmitt-Verhulst, and J. Ghysdael. 1990. Identification of a Ets1 variant protein unaffected in its chromatin and in vitro DNA binding capacities by T cell antigen receptor triggering and intracellular calcium rises. Oncogene. 5: 603-610.
-
(1990)
Oncogene
, vol.5
, pp. 603-610
-
-
Pognonec, P.1
Boulukos, K.E.2
Bosselut, R.3
Boyer, C.4
Schmitt-Verhulst, A.M.5
Ghysdael, J.6
-
43
-
-
0026640141
-
A phorbol ester response element within the human T-cell receptor beta-chain enhancer
-
doi:10.1073/pnas.89.20.9934
-
Prosser, H.M., D. Wotton, A. Gegonne, J. Ghysdael, S. Wang, N.A. Speck, and M.J. Owen. 1992. A phorbol ester response element within the human T-cell receptor beta-chain enhancer. Proc. Natl. Acad. Sci. USA. 89: 9934-9938. doi:10.1073/pnas.89.20.9934
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9934-9938
-
-
Prosser, H.M.1
Wotton, D.2
Gegonne, A.3
Ghysdael, J.4
Wang, S.5
Speck, N.A.6
Owen, M.J.7
-
44
-
-
21744436606
-
Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region
-
doi:10.1126/science.1111915
-
Pufall, M.A., G.M. Lee, M.L. Nelson, H.S. Kang, A. Velyvis, L.E. Kay, L.P. McIntosh, and B.J. Graves. 2005. Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region. Science. 309: 142-145. doi:10.1126/science.1111915
-
(2005)
Science
, vol.309
, pp. 142-145
-
-
Pufall, M.A.1
Lee, G.M.2
Nelson, M.L.3
Kang, H.S.4
Velyvis, A.5
Kay, L.E.6
McIntosh, L.P.7
Graves, B.J.8
-
45
-
-
15244342946
-
Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes
-
doi:10.1016/j.immuni.2005.01.012
-
Sato, T., S. Ohno, T. Hayashi, C. Sato, K. Kohu, M. Satake, and S. Habu. 2005. Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes. Immunity. 22: 317-328. doi:10.1016/j.immuni.2005.01.012
-
(2005)
Immunity
, vol.22
, pp. 317-328
-
-
Sato, T.1
Ohno, S.2
Hayashi, T.3
Sato, C.4
Kohu, K.5
Satake, M.6
Habu, S.7
-
46
-
-
0028242609
-
A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development
-
doi:10.1016/ 0092-8674(94)90140-6
-
Sawada, S., J.D. Scarborough, N. Killeen, and D.R. Littman. 1994. A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell. 77: 917-929. doi:10.1016/ 0092-8674(94)90140-6
-
(1994)
Cell
, vol.77
, pp. 917-929
-
-
Sawada, S.1
Scarborough, J.D.2
Killeen, N.3
Littman, D.R.4
-
47
-
-
38949185052
-
Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development
-
doi:10.1126/science.1151844
-
Setoguchi, R., M. Tachibana, Y. Naoe, S. Muroi, K. Akiyama, C. Tezuka, T. Okuda, and I. Taniuchi. 2008. Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development. Science. 319: 822-825. doi:10.1126/science.1151844
-
(2008)
Science
, vol.319
, pp. 822-825
-
-
Setoguchi, R.1
Tachibana, M.2
Naoe, Y.3
Muroi, S.4
Akiyama, K.5
Tezuka, C.6
Okuda, T.7
Taniuchi, I.8
-
48
-
-
30944467113
-
A guide to choosing fl uorescent proteins
-
doi:10.1038/ nmeth819
-
Shaner, N.C., P.A. Steinbach, and R.Y. Tsien. 2005. A guide to choosing fl uorescent proteins. Nat. Methods. 2: 905-909. doi:10.1038/ nmeth819
-
(2005)
Nat. Methods
, vol.2
, pp. 905-909
-
-
Shaner, N.C.1
Steinbach, P.A.2
Tsien, R.Y.3
-
49
-
-
0035515347
-
The ETS-domain transcription factor family
-
doi:10.1038/35099076
-
Sharrocks, A.D. 2001. The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2: 827-837. doi:10.1038/35099076
-
(2001)
Nat. Rev. Mol. Cell Biol
, vol.2
, pp. 827-837
-
-
Sharrocks, A.D.1
-
50
-
-
2442708080
-
CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: Analysis of the CD4/CD8 lineage decision
-
doi:10.1016/S0065-2776(04) 83003-7
-
Singer, A., and R. Bosselut. 2004. CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: analysis of the CD4/CD8 lineage decision. Adv. Immunol. 83: 91-131. doi:10.1016/S0065-2776(04) 83003-7
-
(2004)
Adv. Immunol
, vol.83
, pp. 91-131
-
-
Singer, A.1
Bosselut, R.2
-
51
-
-
52949145604
-
Lineage fate and intense debate: Myths, models and mechanisms of CD4- versus CD8-lineage choice
-
doi:10.1038/nri2416
-
Singer, A., S. Adoro, and J.H. Park. 2008. Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice. Nat. Rev. Immunol. 8: 788-801. doi:10.1038/nri2416
-
(2008)
Nat. Rev. Immunol
, vol.8
, pp. 788-801
-
-
Singer, A.1
Adoro, S.2
Park, J.H.3
-
52
-
-
0042470456
-
Positive and negative selection of T cells
-
doi:10.1146/annurev .immunol.21.120601.141107
-
Starr, T.K., S.C. Jameson, and K.A. Hogquist. 2003. Positive and negative selection of T cells. Annu. Rev. Immunol. 21: 139-176. doi:10.1146/annurev .immunol.21.120601.141107
-
(2003)
Annu. Rev. Immunol
, vol.21
, pp. 139-176
-
-
Starr, T.K.1
Jameson, S.C.2
Hogquist, K.A.3
-
53
-
-
16844375768
-
The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection
-
doi:10.1038/ni1183
-
Sun, G., X. Liu, P. Mercado, S.R. Jenkinson, M. Kypriotou, L. Feigenbaum, P. Galéra, and R. Bosselut. 2005. The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection. Nat. Immunol. 6: 373-381. doi:10.1038/ni1183
-
(2005)
Nat. Immunol
, vol.6
, pp. 373-381
-
-
Sun, G.1
Liu, X.2
Mercado, P.3
Jenkinson, S.R.4
Kypriotou, M.5
Feigenbaum, L.6
Galéra, P.7
Bosselut, R.8
-
54
-
-
0028904213
-
Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: A new perspective on thymic commitment and selection
-
doi:10.1016/1074-7613(95)90149-3
-
Suzuki, H., J.A. Punt, L.G. Granger, and A. Singer. 1995. Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection. Immunity. 2: 413-425. doi:10.1016/1074-7613(95)90149-3
-
(1995)
Immunity
, vol.2
, pp. 413-425
-
-
Suzuki, H.1
Punt, J.A.2
Granger, L.G.3
Singer, A.4
-
55
-
-
0027339306
-
CD69 expression during selection and maturation of CD4+8+ thymocytes
-
doi:10.1002/eji.1830230326
-
Swat, W., M. Dessing, H. von Boehmer, and P. Kisielow. 1993. CD69 expression during selection and maturation of CD4+8+ thymocytes. Eur. J. Immunol. 23: 739-746. doi:10.1002/eji.1830230326
-
(1993)
Eur. J. Immunol
, vol.23
, pp. 739-746
-
-
Swat, W.1
Dessing, M.2
von Boehmer, H.3
Kisielow, P.4
-
56
-
-
33644845679
-
Journey through the thymus: Stromal guides for T-cell development and selection
-
doi:10.1038/ nri1781
-
Takahama, Y. 2006. Journey through the thymus: stromal guides for T-cell development and selection. Nat. Rev. Immunol. 6: 127-135. doi:10.1038/ nri1781
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 127-135
-
-
Takahama, Y.1
-
57
-
-
18744398397
-
Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
-
doi:10.1016/S0092-8674(02) 01111-X
-
Taniuchi, I., M. Osato, T. Egawa, M.J. Sunshine, S.C. Bae, T. Komori, Y. Ito, and D.R. Littman. 2002a. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell. 111: 621-633. doi:10.1016/S0092-8674(02) 01111-X
-
(2002)
Cell
, vol.111
, pp. 621-633
-
-
Taniuchi, I.1
Osato, M.2
Egawa, T.3
Sunshine, M.J.4
Bae, S.C.5
Komori, T.6
Ito, Y.7
Littman, D.R.8
-
58
-
-
0036864610
-
Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation
-
Taniuchi, I., M.J. Sunshine, R. Festenstein, and D.R. Littman. 2002b. Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation. Mol. Cell. 10: 1083-1096.
-
(2002)
Mol. Cell
, vol.10
, pp. 1083-1096
-
-
Taniuchi, I.1
Sunshine, M.J.2
Festenstein, R.3
Littman, D.R.4
-
59
-
-
2442688211
-
The CD4/CD8 lineage choice: New insights into epigenetic regulation during T cell development
-
doi:10.1016/S0065-2776(04)83002-5
-
Taniuchi, I., W. Ellmeier, and D.R. Littman. 2004. The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development. Adv. Immunol. 83: 55-89. doi:10.1016/S0065-2776(04)83002-5
-
(2004)
Adv. Immunol
, vol.83
, pp. 55-89
-
-
Taniuchi, I.1
Ellmeier, W.2
Littman, D.R.3
-
60
-
-
1642357581
-
Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes
-
Telfer, J.C., E.E. Hedblom, M.K. Anderson, M.N. Laurent, and E.V. Rothenberg. 2004. Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes. J. Immunol. 172: 4359-4370.
-
(2004)
J. Immunol
, vol.172
, pp. 4359-4370
-
-
Telfer, J.C.1
Hedblom, E.E.2
Anderson, M.K.3
Laurent, M.N.4
Rothenberg, E.V.5
-
61
-
-
2542476264
-
The regulation of CD5 expression in murine T cells
-
doi:10.1186/1471-2199-2-5
-
Tung, J.W., S.S. Kunnavatana, L.A. Herzenberg, and L.A. Herzenberg. 2001. The regulation of CD5 expression in murine T cells. BMC Mol. Biol. 2: 5. doi:10.1186/1471-2199-2-5
-
(2001)
BMC Mol. Biol
, vol.2
, pp. 5
-
-
Tung, J.W.1
Kunnavatana, S.S.2
Herzenberg, L.A.3
Herzenberg, L.A.4
-
62
-
-
0036229862
-
When Ets transcription factors meet their partners
-
doi:10.1002/bies. 10068
-
Verger, A., and M. Duterque-Coquillaud. 2002. When Ets transcription factors meet their partners. Bioessays. 24: 362-370. doi:10.1002/bies. 10068
-
(2002)
Bioessays
, vol.24
, pp. 362-370
-
-
Verger, A.1
Duterque-Coquillaud, M.2
-
63
-
-
70349247895
-
CD4-CD8 lineage differentiation: Thpoking into the nucleus
-
doi:10.4049/jimmunol .0901041
-
Wang, L., and R. Bosselut. 2009. CD4-CD8 lineage differentiation: Thpoking into the nucleus. J. Immunol. 183: 2903-2910. doi:10.4049/jimmunol .0901041
-
(2009)
J. Immunol
, vol.183
, pp. 2903-2910
-
-
Wang, L.1
Bosselut, R.2
-
64
-
-
52549133772
-
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells
-
doi:10.1038/ni.1647
-
Wang, L., K.F. Wildt, J. Zhu, X. Zhang, L. Feigenbaum, L. Tessarollo, W.E. Paul, B.J. Fowlkes, and R. Bosselut. 2008a. Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nat. Immunol. 9: 1122-1130. doi:10.1038/ni.1647
-
(2008)
Nat. Immunol
, vol.9
, pp. 1122-1130
-
-
Wang, L.1
Wildt, K.F.2
Zhu, J.3
Zhang, X.4
Feigenbaum, L.5
Tessarollo, L.6
Paul, W.E.7
Fowlkes, B.J.8
Bosselut, R.9
-
65
-
-
57449108862
-
The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4+ T cells
-
doi:10.1016/j.immuni.2008.09.019
-
Wang, L., K.F. Wildt, E. Castro, Y. Xiong, L. Feigenbaum, L. Tessarollo, and R. Bosselut. 2008b. The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4+ T cells. Immunity. 29: 876-887. doi:10.1016/j.immuni.2008.09.019
-
(2008)
Immunity
, vol.29
, pp. 876-887
-
-
Wang, L.1
Wildt, K.F.2
Castro, E.3
Xiong, Y.4
Feigenbaum, L.5
Tessarollo, L.6
Bosselut, R.7
-
66
-
-
38949192274
-
The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer
-
Wildt, K.F., G. Sun, B. Grueter, M. Fischer, M. Zamisch, M. Ehlers, and R. Bosselut. 2007. The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer. J. Immunol. 179: 4405-4414.
-
(2007)
J. Immunol
, vol.179
, pp. 4405-4414
-
-
Wildt, K.F.1
Sun, G.2
Grueter, B.3
Fischer, M.4
Zamisch, M.5
Ehlers, M.6
Bosselut, R.7
-
67
-
-
0038610795
-
Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis
-
doi:10.1073/pnas.1232420100
-
Woolf, E., C. Xiao, O. Fainaru, J. Lotem, D. Rosen, V. Negreanu, Y. Bernstein, D. Goldenberg, O. Brenner, G. Berke, et al. 2003. Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis. Proc. Natl. Acad. Sci. USA. 100: 7731-7736. doi:10.1073/pnas.1232420100
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7731-7736
-
-
Woolf, E.1
Xiao, C.2
Fainaru, O.3
Lotem, J.4
Rosen, D.5
Negreanu, V.6
Bernstein, Y.7
Goldenberg, D.8
Brenner, O.9
Berke, G.10
-
68
-
-
0037450683
-
In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells
-
doi:10.1084/jem.20021765
-
Yu, Q., B. Erman, A. Bhandoola, S.O. Sharrow, and A. Singer. 2003. In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells. J. Exp. Med. 197: 475-487. doi:10.1084/jem.20021765
-
(2003)
J. Exp. Med
, vol.197
, pp. 475-487
-
-
Yu, Q.1
Erman, B.2
Bhandoola, A.3
Sharrow, S.O.4
Singer, A.5
|