-
2
-
-
0030949463
-
Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or Apc
-
Morin, P.J. et al. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or Apc. Science 275, 1787-1790 (1997).
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
-
3
-
-
0031936192
-
Apc1638N: A mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts
-
Smits, R. et al. Apc1638N: A mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts. Gastroenterology 114, 275-283 (1998).
-
(1998)
Gastroenterology
, vol.114
, pp. 275-283
-
-
Smits, R.1
-
4
-
-
0032521433
-
Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
-
Sparks, A.B., Morin, P.J., Vogelstein, B. & Kinzler, K.W. Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res. 58, 1130-1134 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 1130-1134
-
-
Sparks, A.B.1
Morin, P.J.2
Vogelstein, B.3
Kinzler, K.W.4
-
5
-
-
11944252481
-
Germ-line mutations of the Apc gene in 53 familial adenomatous polyposis patients
-
Miyoshi, Y. et al. Germ-line mutations of the Apc gene in 53 familial adenomatous polyposis patients. Proc. Natl. Acad. Sci. USA 89, 4452-4456 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4452-4456
-
-
Miyoshi, Y.1
-
6
-
-
0027763498
-
Molecular diagnosis of familial adenomatous polyposis
-
Powell, S.M. et al. Molecular diagnosis of familial adenomatous polyposis. N. Engl. J. Med. 329, 1982-1987 (1993).
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1982-1987
-
-
Powell, S.M.1
-
7
-
-
0027503873
-
Coexistence of somatic and germ-line mutations of APC gene in desmoid tumors from patients with familial adenomatous polyposis
-
Miyaki, M. et al. Coexistence of somatic and germ-line mutations of APC gene in desmoid tumors from patients with familial adenomatous polyposis. Cancer Res. 53, 5079-5082 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 5079-5082
-
-
Miyaki, M.1
-
8
-
-
0030975671
-
-/- colon carcinoma
-
-/- colon carcinoma. Science 275, 1784-1787 (1997).
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
-
9
-
-
0035956913
-
Top-down morphogenesis of colorectal tumors
-
Shih, I.M. et al. Top-down morphogenesis of colorectal tumors. Proc. Natl. Acad. Sci. USA 98, 2640-2645 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2640-2645
-
-
Shih, I.M.1
-
10
-
-
0035067391
-
A role for the Adenomatous Polyposis Coli protein in chromosome segregation
-
Kaplan, K.B. et al. A role for the Adenomatous Polyposis Coli protein in chromosome segregation. Nat. Cell Biol. 3, 429-432 (2001).
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 429-432
-
-
Kaplan, K.B.1
-
11
-
-
0035070046
-
Mutations in the APC tumour suppressor gene cause chromosomal instability
-
Fodde, R. et al. Mutations in the APC tumour suppressor gene cause chromosomal instability. Nat. Cell Biol. 3, 433-438 (2001).
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 433-438
-
-
Fodde, R.1
-
12
-
-
0042383366
-
+ lymphoid-restricted bone marrow cells with T precursor potential
-
+ lymphoid-restricted bone marrow cells with T precursor potential. Nat. Immunol. 4, 866-873 (2003).
-
(2003)
Nat. Immunol.
, vol.4
, pp. 866-873
-
-
Martin, C.H.1
-
13
-
-
0029962079
-
Early T lymphocyte progenitors
-
Shortman, K. & Wu, L. Early T lymphocyte progenitors. Annu. Rev. Immunol. 14, 29-47 (1996).
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 29-47
-
-
Shortman, K.1
Wu, L.2
-
14
-
-
0037320932
-
Thymopoiesis independent of common lymphoid progenitors
-
Allman, D. et al. Thymopoiesis independent of common lymphoid progenitors. Nat. Immunol. 4, 168-174 (2003).
-
(2003)
Nat. Immunol.
, vol.4
, pp. 168-174
-
-
Allman, D.1
-
15
-
-
4644329449
-
Circulating hematopoietic progenitors with T lineage potential
-
Schwarz, B.A. & Bhandoola, A. Circulating hematopoietic progenitors with T lineage potential. Nat. Immunol. 5, 953-960 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 953-960
-
-
Schwarz, B.A.1
Bhandoola, A.2
-
16
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo, M., Weissman, I.L. & Akashi, K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91, 661-672 (1997).
-
(1997)
Cell
, vol.91
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
17
-
-
2942516896
-
Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages
-
Porritt, H.E. et al. Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 20, 735-745 (2004).
-
(2004)
Immunity
, vol.20
, pp. 735-745
-
-
Porritt, H.E.1
-
18
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke, F. et al. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10, 547-558 (1999).
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
-
19
-
-
0036916440
-
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
-
Schmitt, T.M. & Zuniga-Pflucker, J.C. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 17, 749-756 (2002).
-
(2002)
Immunity
, vol.17
, pp. 749-756
-
-
Schmitt, T.M.1
Zuniga-Pflucker, J.C.2
-
20
-
-
0031172368
-
Aspects of lymphocyte developmental biology
-
von Boehmer, H. Aspects of lymphocyte developmental biology. Immunol. Today 18, 260-262 (1997).
-
(1997)
Immunol. Today
, vol.18
, pp. 260-262
-
-
von Boehmer, H.1
-
21
-
-
0036070308
-
Inactivation of Notch1 impairs VDJβ rearrangement and allows pre-TCR-independent survival of early αβ Lineage Thymocytes
-
Wolfer, A., Wilson, A., Nemir, M., MacDonald, H.R. & Radtke, F. Inactivation of Notch1 impairs VDJβ rearrangement and allows pre-TCR-independent survival of early αβ Lineage Thymocytes. Immunity 16, 869-879 (2002).
-
(2002)
Immunity
, vol.16
, pp. 869-879
-
-
Wolfer, A.1
Wilson, A.2
Nemir, M.3
MacDonald, H.R.4
Radtke, F.5
-
22
-
-
0032532301
-
Critical involvement of Tcf-1 in expansion of thymocytes
-
Schilham, M.W. et al. Critical involvement of Tcf-1 in expansion of thymocytes. J. Immunol. 161, 3984-3991 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 3984-3991
-
-
Schilham, M.W.1
-
24
-
-
0031883962
-
Redundant regulation of T cell differentiation and TCRα gene expression by the transcription factors LEF-1 and TCF-1
-
Okamura, R.M. et al. Redundant regulation of T cell differentiation and TCRα gene expression by the transcription factors LEF-1 and TCF-1. Immunity 8, 11-20 (1998).
-
(1998)
Immunity
, vol.8
, pp. 11-20
-
-
Okamura, R.M.1
-
25
-
-
0346121607
-
Deletion of β-catenin impairs T cell development
-
Xu, Y., Banerjee, D., Huelsken, J., Birchmeier, W. & Sen, J.M. Deletion of β-catenin impairs T cell development. Nat. Immunol. 4, 1177-1182 (2003).
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1177-1182
-
-
Xu, Y.1
Banerjee, D.2
Huelsken, J.3
Birchmeier, W.4
Sen, J.M.5
-
26
-
-
0035554684
-
Somatic activation of β-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development
-
Gounari, F. et al. Somatic activation of β-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development. Nat. Immunol. 2, 863-869 (2001).
-
(2001)
Nat. Immunol.
, vol.2
, pp. 863-869
-
-
Gounari, F.1
-
27
-
-
0028567875
-
A targeted chain-termination mutation in the mouse APC gene results in multiple intestinal tumors
-
Fodde, R. et al. A targeted chain-termination mutation in the mouse APC gene results in multiple intestinal tumors. Proc. Natl. Acad. Sci. USA 91, 8969-8973 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
-
28
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser, A.R., Pitot, H.C. & Dove, W.F. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247, 322-324 (1990).
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pitot, H.C.2
Dove, W.F.3
-
29
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima, M. et al. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc. Natl. Acad. Sci. USA 92, 4482-4486 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
-
30
-
-
0033230616
-
Intestinal polyposis in mice with a dominant stable mutation of the β-catenin gene
-
Harada, N. et al. Intestinal polyposis in mice with a dominant stable mutation of the β-catenin gene. EMBO J. 18, 5931-5942 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 5931-5942
-
-
Harada, N.1
-
31
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
Lee, P.P. et al. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 15, 763-774 (2001).
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
-
32
-
-
0028033447
-
Developmental regulation of bcl-2 expression in the thymus
-
Moore, N.C., Anderson, G., Williams, G.T., Owen, J.J. & Jenkinson, E.J. Developmental regulation of bcl-2 expression in the thymus. Immunology 81, 115-119 (1994).
-
(1994)
Immunology
, vol.81
, pp. 115-119
-
-
Moore, N.C.1
Anderson, G.2
Williams, G.T.3
Owen, J.J.4
Jenkinson, E.J.5
-
33
-
-
0027079356
-
Inhibition of T-cell receptor β-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck
-
Anderson, S.J., Abraham, K.M., Nakayama, T., Singer, A. & Perlmutter, R.M. Inhibition of T-cell receptor β-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck. EMBO J. 11, 4877-4886 (1992).
-
(1992)
EMBO J.
, vol.11
, pp. 4877-4886
-
-
Anderson, S.J.1
Abraham, K.M.2
Nakayama, T.3
Singer, A.4
Perlmutter, R.M.5
-
34
-
-
20144370145
-
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance
-
Duncan, A.W. et al. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nat. Immunol. 6, 314-322 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 314-322
-
-
Duncan, A.W.1
-
35
-
-
8644219672
-
LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis
-
Galceran, J., Sustmann, C., Hsu, S.C., Folberth, S. & Grosschedl, R. LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis. Genes Dev. 18, 2718-2723 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 2718-2723
-
-
Galceran, J.1
Sustmann, C.2
Hsu, S.C.3
Folberth, S.4
Grosschedl, R.5
-
36
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
Nicolas, M. et al. Notch1 functions as a tumor suppressor in mouse skin. Nat. Genet. 33, 416-421 (2003).
-
(2003)
Nat. Genet.
, vol.33
, pp. 416-421
-
-
Nicolas, M.1
-
37
-
-
0003364533
-
Interactions between Wingless and Notch during the assignment of cell fates in Drosophila
-
Martinez Arias, A. Interactions between Wingless and Notch during the assignment of cell fates in Drosophila. Int. J. Dev. Biol. 42, 325-333 (1998).
-
(1998)
Int. J. Dev. Biol.
, vol.42
, pp. 325-333
-
-
Martinez Arias, A.1
-
38
-
-
9144229104
-
Requirement for cyclin D3 in lymphocyte development and T cell leukemias
-
Sicinska, E. et al. Requirement for cyclin D3 in lymphocyte development and T cell leukemias. Cancer Cell 4, 451-461 (2003).
-
(2003)
Cancer Cell
, vol.4
, pp. 451-461
-
-
Sicinska, E.1
-
40
-
-
0024281597
-
A transcriptional enhancer 3′ of C β 2 in the T cell receptor β locus
-
McDougall, S., Peterson, C.L. & Calame, K. A transcriptional enhancer 3′ of C β 2 in the T cell receptor β locus. Science 241, 205-208 (1988).
-
(1988)
Science
, vol.241
, pp. 205-208
-
-
McDougall, S.1
Peterson, C.L.2
Calame, K.3
-
41
-
-
0029066006
-
APC binds to the novel protein EB1
-
Su, L.K. et al. APC binds to the novel protein EB1. Cancer Res. 55, 2972-2977 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 2972-2977
-
-
Su, L.K.1
-
42
-
-
0035176077
-
Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 β phosphorylation
-
Zumbrunn, J., Kinoshita, K., Hyman, A.A. & Nathke, I.S. Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 β phosphorylation. Curr. Biol. 11, 44-49 (2001).
-
(2001)
Curr. Biol.
, vol.11
, pp. 44-49
-
-
Zumbrunn, J.1
Kinoshita, K.2
Hyman, A.A.3
Nathke, I.S.4
-
43
-
-
0037459109
-
Centromeres and kinetochores: From epigenetics to mitotic checkpoint signaling
-
Cleveland, D.W., Mao, Y. & Sullivan, K.F. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell 112, 407-421 (2003).
-
(2003)
Cell
, vol.112
, pp. 407-421
-
-
Cleveland, D.W.1
Mao, Y.2
Sullivan, K.F.3
-
44
-
-
0027942033
-
Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle
-
Rieder, C.L., Schultz, A., Cole, R. & Sluder, G. Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle. J. Cell Biol. 127, 1301-1310 (1994).
-
(1994)
J. Cell Biol.
, vol.127
, pp. 1301-1310
-
-
Rieder, C.L.1
Schultz, A.2
Cole, R.3
Sluder, G.4
-
45
-
-
0028872743
-
Mitotic forces control a cell-cycle checkpoint
-
Li, X. & Nicklas, R.B. Mitotic forces control a cell-cycle checkpoint. Nature 373, 630-632 (1995).
-
(1995)
Nature
, vol.373
, pp. 630-632
-
-
Li, X.1
Nicklas, R.B.2
-
46
-
-
0029065488
-
Crucial role of the pre-T-cell receptor α gene in development of αβ but not γδ T cells
-
Fehling, H.J., Krotkova, A., Saint-Ruf, C. & von Boehmer, H. Crucial role of the pre-T-cell receptor α gene in development of αβ but not γδ T cells. Nature 375, 795-798 (1995).
-
(1995)
Nature
, vol.375
, pp. 795-798
-
-
Fehling, H.J.1
Krotkova, A.2
Saint-Ruf, C.3
von Boehmer, H.4
-
47
-
-
0029924217
-
Productive T-cell receptor β-chain gene rearrangement: Coincident regulation of cell cycle and clonality during development in vivo
-
Hoffman, E.S. et al. Productive T-cell receptor β-chain gene rearrangement: Coincident regulation of cell cycle and clonality during development in vivo. Genes Dev. 10, 948-962 (1996).
-
(1996)
Genes Dev.
, vol.10
, pp. 948-962
-
-
Hoffman, E.S.1
-
48
-
-
2142654263
-
Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation
-
Ciofani, M. et al. Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation. J. Immunol. 172, 5230-5239 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 5230-5239
-
-
Ciofani, M.1
-
49
-
-
0036097258
-
Tracing lymphopoiesis with the aid of a pTα-controlled reporter gene
-
Gounari, F. et al. Tracing lymphopoiesis with the aid of a pTα-controlled reporter gene. Nat. Immunol. 3, 489-496 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 489-496
-
-
Gounari, F.1
-
50
-
-
8244255004
-
The importance of efficacy and partial agonism in evaluating models of B lymphocyte activation
-
Hodgkin, P.D. et al. The importance of efficacy and partial agonism in evaluating models of B lymphocyte activation. Int. Rev. Immunol. 15, 101-127 (1997).
-
(1997)
Int. Rev. Immunol.
, vol.15
, pp. 101-127
-
-
Hodgkin, P.D.1
|