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Volumn 112, Issue 3, 2008, Pages 626-634

TGF-2signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

EID: 50949123978     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-10-115618     Document Type: Article
Times cited : (63)

References (61)
  • 1
    • 33847678449 scopus 로고    scopus 로고
    • Early decisions in lymphoid development
    • Ye M, Graf T. Early decisions in lymphoid development. Curr Opin Immunol. 2007;19:123-128.
    • (2007) Curr Opin Immunol , vol.19 , pp. 123-128
    • Ye, M.1    Graf, T.2
  • 3
    • 0035496231 scopus 로고    scopus 로고
    • Lymphostromal interactions in thymic development and function
    • Anderson G, Jenkinson EJ. Lymphostromal interactions in thymic development and function. Nat Rev Immunol. 2001;1:31-40.
    • (2001) Nat Rev Immunol , vol.1 , pp. 31-40
    • Anderson, G.1    Jenkinson, E.J.2
  • 4
    • 17444372347 scopus 로고    scopus 로고
    • Changes in thymic function with age and during the treatment of HIV infection
    • Douek DC, McFarland RD, Keiser PH, et al. Changes in thymic function with age and during the treatment of HIV infection. Nature. 1998;396: 690-695.
    • (1998) Nature , vol.396 , pp. 690-695
    • Douek, D.C.1    McFarland, R.D.2    Keiser, P.H.3
  • 5
    • 0022585737 scopus 로고
    • Changes in the human thymus during aging
    • Steinmann GG. Changes in the human thymus during aging. Curr Top Pathol. 1986;75:43-88.
    • (1986) Curr Top Pathol , vol.75 , pp. 43-88
    • Steinmann, G.G.1
  • 6
    • 20344371900 scopus 로고    scopus 로고
    • Insights into thymic aging and regeneration
    • Taub DD, Longo DL. Insights into thymic aging and regeneration. Immunol Rev. 2005;205:72-93.
    • (2005) Immunol Rev , vol.205 , pp. 72-93
    • Taub, D.D.1    Longo, D.L.2
  • 7
    • 0036311982 scopus 로고    scopus 로고
    • Molecular characterization of the mouse involuted thymus: Aberrations in expression of transcription regulators in thymocyte and epithelial compartments
    • Ortman CL, Dittmar KA, Witte PL, Le PT. Molecular characterization of the mouse involuted thymus: aberrations in expression of transcription regulators in thymocyte and epithelial compartments. Int Immunol. 2002;14:813-822.
    • (2002) Int Immunol , vol.14 , pp. 813-822
    • Ortman, C.L.1    Dittmar, K.A.2    Witte, P.L.3    Le, P.T.4
  • 8
    • 33845239216 scopus 로고    scopus 로고
    • Developmental kinetics, turnover and stimulatory capacity of thymic epithelial cells
    • Gray DH, Seach N, Ueno T, et al. Developmental kinetics, turnover and stimulatory capacity of thymic epithelial cells. Blood. 2006;108:3777-3785.
    • (2006) Blood , vol.108 , pp. 3777-3785
    • Gray, D.H.1    Seach, N.2    Ueno, T.3
  • 9
    • 23844486206 scopus 로고    scopus 로고
    • Effects of castration on thymocyte development in two different models of thymic involution
    • Heng TS, Goldberg GL, Gray DH, Sutherland JS, Chidgey AP, Boyd RL. Effects of castration on thymocyte development in two different models of thymic involution. J Immunol. 2005;175:2982-2993.
    • (2005) J Immunol , vol.175 , pp. 2982-2993
    • Heng, T.S.1    Goldberg, G.L.2    Gray, D.H.3    Sutherland, J.S.4    Chidgey, A.P.5    Boyd, R.L.6
  • 10
    • 23444461765 scopus 로고    scopus 로고
    • Activation of thymic regeneration in mice and humans following androgen blockade
    • Sutherland JS, Goldberg GL, Hammett MV, et al. Activation of thymic regeneration in mice and humans following androgen blockade. J Immunol. 2005;175:2741-2753.
    • (2005) J Immunol , vol.175 , pp. 2741-2753
    • Sutherland, J.S.1    Goldberg, G.L.2    Hammett, M.V.3
  • 11
    • 34548030239 scopus 로고    scopus 로고
    • Multiple prethymic defects underlie age-related loss of T progenitor competence
    • Zediak VP, Maillard I, Bhandoola A. Multiple prethymic defects underlie age-related loss of T progenitor competence. Blood. 2007;110:1161-1167.
    • (2007) Blood , vol.110 , pp. 1161-1167
    • Zediak, V.P.1    Maillard, I.2    Bhandoola, A.3
  • 12
    • 33646141172 scopus 로고    scopus 로고
    • T cell development, ageing and Interleukin-7
    • Aspinall R. T cell development, ageing and Interleukin-7. Mech Ageing Dev. 2006;127:572-578.
    • (2006) Mech Ageing Dev , vol.127 , pp. 572-578
    • Aspinall, R.1
  • 13
    • 0034868746 scopus 로고    scopus 로고
    • Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival
    • Sano S, Takahama Y, Sugawara T, et al. Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival. Immunity. 2001;15:261-273.
    • (2001) Immunity , vol.15 , pp. 261-273
    • Sano, S.1    Takahama, Y.2    Sugawara, T.3
  • 14
    • 1342282246 scopus 로고    scopus 로고
    • IL-12 inhibits thymic involution by enhancing IL-7- and IL-2-induced thymocyte proliferation
    • Li L, Hsu HC, Stockard CR, et al. IL-12 inhibits thymic involution by enhancing IL-7- and IL-2-induced thymocyte proliferation. J Immunol. 2004;172:2909-2916.
    • (2004) J Immunol , vol.172 , pp. 2909-2916
    • Li, L.1    Hsu, H.C.2    Stockard, C.R.3
  • 16
    • 0037407769 scopus 로고    scopus 로고
    • Genealogy, expression, and cellular function of transforming growth factor-beta
    • Govinden R, Bhoola KD. Genealogy, expression, and cellular function of transforming growth factor-beta. Pharmacol Ther. 2003;98:257-265.
    • (2003) Pharmacol Ther , vol.98 , pp. 257-265
    • Govinden, R.1    Bhoola, K.D.2
  • 17
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-beta signals
    • Massagué J. How cells read TGF-beta signals. Nat Rev Mol Cell Biol. 2000;1:169-178.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 169-178
    • Massagué, J.1
  • 18
    • 0034665777 scopus 로고    scopus 로고
    • Transforming growth factor-beta: Pleiotropic role in the regulation of hematopoiesis
    • Fortunel NO, Hatzfeld A, Hatzfeld JA. Transforming growth factor-beta: pleiotropic role in the regulation of hematopoiesis. Blood. 2000;96:2022-2036.
    • (2000) Blood , vol.96 , pp. 2022-2036
    • Fortunel, N.O.1    Hatzfeld, A.2    Hatzfeld, J.A.3
  • 19
    • 0023918023 scopus 로고
    • Transforming growth factor-beta s are equipotent growth inhibitors of interleukin-1-induced thymocyte proliferation
    • Ellingsworth LR, Nakayama D, Segarini P, Dasch J, Carrillo P, Waegell W. Transforming growth factor-beta s are equipotent growth inhibitors of interleukin-1-induced thymocyte proliferation. Cell Immunol. 1988;114:41-54.
    • (1988) Cell Immunol , vol.114 , pp. 41-54
    • Ellingsworth, L.R.1    Nakayama, D.2    Segarini, P.3    Dasch, J.4    Carrillo, P.5    Waegell, W.6
  • 20
    • 0022465625 scopus 로고
    • Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth
    • Kehrl JH, Wakefield LM, Roberts AB, et al. Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth. J Exp Med. 1986;163: 1037-1050.
    • (1986) J Exp Med , vol.163 , pp. 1037-1050
    • Kehrl, J.H.1    Wakefield, L.M.2    Roberts, A.B.3
  • 21
    • 0028230798 scopus 로고
    • Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor beta
    • Takahama Y, Letterio JJ, Suzuki H, Farr AG, Singer A. Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor beta. J Exp Med. 1994;179:1495-1506.
    • (1994) J Exp Med , vol.179 , pp. 1495-1506
    • Takahama, Y.1    Letterio, J.J.2    Suzuki, H.3    Farr, A.G.4    Singer, A.5
  • 22
    • 0028172533 scopus 로고
    • TGF-beta 1 is a potent inducer of human effector T cells
    • Cerwenka A, Bevec D, Majdic O, Knapp W, Holter W. TGF-beta 1 is a potent inducer of human effector T cells. J Immunol. 1994;153:4367-4377.
    • (1994) J Immunol , vol.153 , pp. 4367-4377
    • Cerwenka, A.1    Bevec, D.2    Majdic, O.3    Knapp, W.4    Holter, W.5
  • 23
    • 0028178471 scopus 로고
    • Transforming growth factor-beta 2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression
    • Weller M, Constam DB, Malipiero U, Fontana A. Transforming growth factor-beta 2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression. Eur J Immunol. 1994;24:1293-1300.
    • (1994) Eur J Immunol , vol.24 , pp. 1293-1300
    • Weller, M.1    Constam, D.B.2    Malipiero, U.3    Fontana, A.4
  • 24
    • 0035920554 scopus 로고    scopus 로고
    • Requirement for transforming growth factor beta1 in controlling T cell apoptosis
    • Chen W, Jin W, Tian H, et al. Requirement for transforming growth factor beta1 in controlling T cell apoptosis. J Exp Med. 2001;194:439-453.
    • (2001) J Exp Med , vol.194 , pp. 439-453
    • Chen, W.1    Jin, W.2    Tian, H.3
  • 25
    • 0025951644 scopus 로고
    • Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype
    • Swain SL, Huston G, Tonkonogy S, Weinberg A. Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype. J Immunol. 1991;147:2991-3000.
    • (1991) J Immunol , vol.147 , pp. 2991-3000
    • Swain, S.L.1    Huston, G.2    Tonkonogy, S.3    Weinberg, A.4
  • 26
    • 0027959893 scopus 로고
    • Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype
    • Sad S, Mosmann TR. Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. J Immunol. 1994;153:3514-3522.
    • (1994) J Immunol , vol.153 , pp. 3514-3522
    • Sad, S.1    Mosmann, T.R.2
  • 27
    • 0346024089 scopus 로고    scopus 로고
    • Quantitative trait analysis reveals transforming growth factor-beta2 as a positive regulator of early hematopoietic progenitor and stem cell function
    • Langer JC, Henckaerts E, Orenstein J, Snoeck HW. Quantitative trait analysis reveals transforming growth factor-beta2 as a positive regulator of early hematopoietic progenitor and stem cell function. J Exp Med. 2004;199:5-14.
    • (2004) J Exp Med , vol.199 , pp. 5-14
    • Langer, J.C.1    Henckaerts, E.2    Orenstein, J.3    Snoeck, H.W.4
  • 28
    • 0026053972 scopus 로고
    • Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis
    • Schmid P, Cox D, Bilbe G, Maier R, McMaster GK. Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis. Development. 1991;111:117-130.
    • (1991) Development , vol.111 , pp. 117-130
    • Schmid, P.1    Cox, D.2    Bilbe, G.3    Maier, R.4    McMaster, G.K.5
  • 29
    • 0028972869 scopus 로고
    • Transforming growth factor-beta 3 is required for secondary palate fusion
    • Proetzel G, Pawlowski SA, Wiles MV, et al. Transforming growth factor-beta 3 is required for secondary palate fusion. Nat Genet. 1995;11:409-414.
    • (1995) Nat Genet , vol.11 , pp. 409-414
    • Proetzel, G.1    Pawlowski, S.A.2    Wiles, M.V.3
  • 30
    • 0030609894 scopus 로고    scopus 로고
    • TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes
    • Sanford LP, Ormsby I, Gittenberger-de Groot AC, et al. TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes. Development. 1997;124:2659-2670.
    • (1997) Development , vol.124 , pp. 2659-2670
    • Sanford, L.P.1    Ormsby, I.2    Gittenberger-de Groot, A.C.3
  • 31
    • 0030579203 scopus 로고    scopus 로고
    • TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis
    • Oshima M, Oshima H, Taketo MM. TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. Dev Biol. 1996;179:297-302.
    • (1996) Dev Biol , vol.179 , pp. 297-302
    • Oshima, M.1    Oshima, H.2    Taketo, M.M.3
  • 32
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
    • Shull MM, Ormsby I, Kier AB, et al. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature. 1992;359:693-699.
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1    Ormsby, I.2    Kier, A.B.3
  • 33
    • 0033697670 scopus 로고    scopus 로고
    • TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo
    • Cazac BB, Roes J. TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo. Immunity. 2000;13:443-451.
    • (2000) Immunity , vol.13 , pp. 443-451
    • Cazac, B.B.1    Roes, J.2
  • 34
    • 0346258124 scopus 로고    scopus 로고
    • Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development
    • Macatee TL, Hammond BP, Arenkiel BR, Francis L, Frank DU. Moon AM. Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development. Development. 2003;130:6361-6374.
    • (2003) Development , vol.130 , pp. 6361-6374
    • Macatee, T.L.1    Hammond, B.P.2    Arenkiel, B.R.3    Francis, L.4    Frank, D.U.5    Moon, A.M.6
  • 35
    • 34247328577 scopus 로고    scopus 로고
    • Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells
    • Rossi SW, Jeker LT, Ueno T, et al. Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells. Blood. 2007;109:3803-3811.
    • (2007) Blood , vol.109 , pp. 3803-3811
    • Rossi, S.W.1    Jeker, L.T.2    Ueno, T.3
  • 36
    • 34247392402 scopus 로고    scopus 로고
    • DonorT-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation
    • Hauri-Hohl MM, Keller MP, Gill J, et al. DonorT-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation. Blood. 2007;109:4080-4088.
    • (2007) Blood , vol.109 , pp. 4080-4088
    • Hauri-Hohl, M.M.1    Keller, M.P.2    Gill, J.3
  • 37
    • 0027465451 scopus 로고
    • MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus
    • Anderson G, Jenkinson EJ, Moore NC, Owen JJ. MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus. Nature. 1993;362:70-73.
    • (1993) Nature , vol.362 , pp. 70-73
    • Anderson, G.1    Jenkinson, E.J.2    Moore, N.C.3    Owen, J.J.4
  • 38
    • 4644329449 scopus 로고    scopus 로고
    • Circulating hematopoietic progenitors with T lineage potential
    • Schwarz BA, Bhandoola A. Circulating hematopoietic progenitors with T lineage potential. Nat Immunol. 2004;5:953-960.
    • (2004) Nat Immunol , vol.5 , pp. 953-960
    • Schwarz, B.A.1    Bhandoola, A.2
  • 40
    • 0034651657 scopus 로고    scopus 로고
    • Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy
    • Sempowski GD, Hale LP, Sundy JS, et al. Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy. J Immunol. 2000;164:2180-2187.
    • (2000) J Immunol , vol.164 , pp. 2180-2187
    • Sempowski, G.D.1    Hale, L.P.2    Sundy, J.S.3
  • 41
    • 0027279048 scopus 로고
    • Testosterone induces expression of transforming growth factor-beta 1 in the murine thymus
    • Olsen NJ, Zhou P, Ong H, Kovacs WJ. Testosterone induces expression of transforming growth factor-beta 1 in the murine thymus. J Steroid Biochem Mol Biol. 1993;45:327-332.
    • (1993) J Steroid Biochem Mol Biol , vol.45 , pp. 327-332
    • Olsen, N.J.1    Zhou, P.2    Ong, H.3    Kovacs, W.J.4
  • 42
    • 0036298048 scopus 로고    scopus 로고
    • Burn-induced thymic apoptosis corresponds with altered TGF-beta(1) and Smad 2/3
    • Hobson KG, Cho K, Adamson LK, Greenhalgh DG. Burn-induced thymic apoptosis corresponds with altered TGF-beta(1) and Smad 2/3. J Surg Res. 2002;105:4-9.
    • (2002) J Surg Res , vol.105 , pp. 4-9
    • Hobson, K.G.1    Cho, K.2    Adamson, L.K.3    Greenhalgh, D.G.4
  • 43
    • 0029836715 scopus 로고    scopus 로고
    • Difference in antigen presentation pathways between cortical and medullary thymic epithelial cells
    • Kasai M, Hirokawa K, Kajino K, et al. Difference in antigen presentation pathways between cortical and medullary thymic epithelial cells. Eur J Immunol. 1996;26:2101-2107.
    • (1996) Eur J Immunol , vol.26 , pp. 2101-2107
    • Kasai, M.1    Hirokawa, K.2    Kajino, K.3
  • 44
    • 0029153647 scopus 로고
    • The role of thymocytes in regulating thymic epithelial cell growth and function
    • Meilin A, Shoham J, Schreiber L, Sharabi Y. The role of thymocytes in regulating thymic epithelial cell growth and function. Scand J Immunol. 1995;42:185-190.
    • (1995) Scand J Immunol , vol.42 , pp. 185-190
    • Meilin, A.1    Shoham, J.2    Schreiber, L.3    Sharabi, Y.4
  • 45
    • 1642580757 scopus 로고    scopus 로고
    • Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
    • Matloubian M, Lo CG, Cinamon G, et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature. 2004;427:355-360.
    • (2004) Nature , vol.427 , pp. 355-360
    • Matloubian, M.1    Lo, C.G.2    Cinamon, G.3
  • 46
    • 0030770411 scopus 로고    scopus 로고
    • Latent transforming growth factor beta1 activation in situ: Quantitative and functional evidence after low-dose gamma-irradiation
    • Ehrhart EJ, Segarini P, Tsang ML. Carroll AG, Barcellos-Hoff MH. Latent transforming growth factor beta1 activation in situ: quantitative and functional evidence after low-dose gamma-irradiation. FASEB J. 1997;11:991-1002.
    • (1997) FASEB J , vol.11 , pp. 991-1002
    • Ehrhart, E.J.1    Segarini, P.2    Tsang, M.L.3    Carroll, A.G.4    Barcellos-Hoff, M.H.5
  • 47
    • 0034960320 scopus 로고    scopus 로고
    • TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu
    • Chen W, Frank ME, Jin W, Wahl SM. TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu. Immunity. 2001;14: 715-725.
    • (2001) Immunity , vol.14 , pp. 715-725
    • Chen, W.1    Frank, M.E.2    Jin, W.3    Wahl, S.M.4
  • 48
    • 0037108674 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 mediates cellular response to DNA damage in situ
    • Ewan KB, Henshall-Powell RL, Ravani SA, et al. Transforming growth factor-beta1 mediates cellular response to DNA damage in situ. Cancer Res. 2002;62:5627-5631.
    • (2002) Cancer Res , vol.62 , pp. 5627-5631
    • Ewan, K.B.1    Henshall-Powell, R.L.2    Ravani, S.A.3
  • 49
    • 24644441010 scopus 로고    scopus 로고
    • Letterio JJTGF-beta signaling in T cells: roles in lymphoid and epithelial neoplasia. Oncogene. 2005;24:5701-5712.
    • Letterio JJTGF-beta signaling in T cells: roles in lymphoid and epithelial neoplasia. Oncogene. 2005;24:5701-5712.
  • 50
    • 0034858660 scopus 로고    scopus 로고
    • The development and evolution of the pharyngeal arches
    • Graham A. The development and evolution of the pharyngeal arches. J Anat. 2001;199:133-141.
    • (2001) J Anat , vol.199 , pp. 133-141
    • Graham, A.1
  • 51
    • 0034554749 scopus 로고    scopus 로고
    • Autonomic neurogenesis and apoptosis are alternative fates of progenitor cell communities induced by TGFbeta
    • Hagedorn L, Floris J, Suter U, Sommer L. Autonomic neurogenesis and apoptosis are alternative fates of progenitor cell communities induced by TGFbeta. Dev Biol. 2000;228:57-72.
    • (2000) Dev Biol , vol.228 , pp. 57-72
    • Hagedorn, L.1    Floris, J.2    Suter, U.3    Sommer, L.4
  • 52
    • 0029897371 scopus 로고    scopus 로고
    • Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members
    • Shah NM, Groves AK, Anderson DJ. Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members. Cell. 1996;85: 331-343.
    • (1996) Cell , vol.85 , pp. 331-343
    • Shah, N.M.1    Groves, A.K.2    Anderson, D.J.3
  • 53
    • 0032871477 scopus 로고    scopus 로고
    • P0 and PMP22 mark a multipotent neural crest-derived cell type that displays community effects in response to TGF-beta family factors
    • Hagedorn L, Suter U, Sommer L. P0 and PMP22 mark a multipotent neural crest-derived cell type that displays community effects in response to TGF-beta family factors. Development. 1999;126: 3781-3794.
    • (1999) Development , vol.126 , pp. 3781-3794
    • Hagedorn, L.1    Suter, U.2    Sommer, L.3
  • 54
    • 14644418529 scopus 로고    scopus 로고
    • Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome
    • Wurdak H, Ittner LM, Lang KS, et al. Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome. Genes Dev. 2005;19:530-535.
    • (2005) Genes Dev , vol.19 , pp. 530-535
    • Wurdak, H.1    Ittner, L.M.2    Lang, K.S.3
  • 55
    • 0021334469 scopus 로고
    • Dependence of thymus development on derivatives of the neural crest
    • Bockman DE, Kirby ML. Dependence of thymus development on derivatives of the neural crest. Science. 1984;223:498-500.
    • (1984) Science , vol.223 , pp. 498-500
    • Bockman, D.E.1    Kirby, M.L.2
  • 57
    • 33344456213 scopus 로고    scopus 로고
    • Transforming growth factor-beta2 is involved in quantitative genetic variation in thymic involution
    • Kumar R, Langer JC, Snoeck HW. Transforming growth factor-beta2 is involved in quantitative genetic variation in thymic involution. Blood. 2006;107:1974-1979.
    • (2006) Blood , vol.107 , pp. 1974-1979
    • Kumar, R.1    Langer, J.C.2    Snoeck, H.W.3
  • 58
    • 0024362473 scopus 로고
    • Interleukin 7 (murine pre-B cell growth factor/lymphopoietin 1) stimulates thymocyte growth: Regulation by transforming growth factor beta
    • Chantry D, Turner M, Feldmann M. Interleukin 7 (murine pre-B cell growth factor/lymphopoietin 1) stimulates thymocyte growth: regulation by transforming growth factor beta. Eur J Immunol. 1989;19:783-786.
    • (1989) Eur J Immunol , vol.19 , pp. 783-786
    • Chantry, D.1    Turner, M.2    Feldmann, M.3
  • 59
    • 0031569111 scopus 로고    scopus 로고
    • TGF-beta differentially modulates epidermal growth factormediated increases in leukemia-inhibitory factor, IL-6, IL-1 alpha, and IL-1 beta in human thymic epithelial cells
    • Schluns KS, Cook JE, Le PT. TGF-beta differentially modulates epidermal growth factormediated increases in leukemia-inhibitory factor, IL-6, IL-1 alpha, and IL-1 beta in human thymic epithelial cells. J Immunol. 1997;158:2704-2712.
    • (1997) J Immunol , vol.158 , pp. 2704-2712
    • Schluns, K.S.1    Cook, J.E.2    Le, P.T.3
  • 60
    • 0141679073 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 down-regulates expression of chemokine stromal cell-derived factor-1: Functional consequences in cell migration and adhesion
    • Wright N, de Lera TL, García-Moruja C, et al. Transforming growth factor-beta1 down-regulates expression of chemokine stromal cell-derived factor-1: functional consequences in cell migration and adhesion. Blood. 2003;102:1978-1984.
    • (2003) Blood , vol.102 , pp. 1978-1984
    • Wright, N.1    de Lera, T.L.2    García-Moruja, C.3
  • 61
    • 0025878150 scopus 로고
    • Reentry of T cells to the adult thymus is restricted to activated T cells
    • Agus DB, Surh CD, Sprent J. Reentry of T cells to the adult thymus is restricted to activated T cells. J Exp Med. 1991;173:1039-1046.
    • (1991) J Exp Med , vol.173 , pp. 1039-1046
    • Agus, D.B.1    Surh, C.D.2    Sprent, J.3


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