TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis

Cell and Tissue Research

Volumn 347, Issue 1, 2012, Pages 117-128

  Samarakoon, Rohan ^a   Overstreet, Jessica M ^a   Higgins, Stephen P ^a   Higgins, Paul J ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Fibrosis; p53; PAI 1; TGF 1; Transcription

Indexed keywords

GEFITINIB; PIFITHRIN ALPHA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN P53; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; UPSTREAM STIMULATORY FACTOR; UPSTREAM STIMULATORY FACTOR 2;

BINDING AFFINITY; BINDING SITE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHRONIC KIDNEY DISEASE; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE COURSE; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FIBROGENESIS; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; HUMAN; KIDNEY FIBROSIS; KIDNEY INJURY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; NONHUMAN; PHENOTYPE; PLASMINOGEN ACTIVATOR INHIBITOR 1 GENE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; STEM CELL MOBILIZATION; UPREGULATION; URETER OBSTRUCTION;

ANIMALS; FIBROSIS; HUMANS; KIDNEY; KIDNEY DISEASES; PLASMINOGEN ACTIVATOR INHIBITOR 1; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1; TUMOR SUPPRESSOR PROTEIN P53; URETERAL OBSTRUCTION;

EID: 84856255286     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-011-1181-y     Document Type: Review

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