Treatment of chronic tubulointerstitial disease: A new concept

Kidney International

Volumn 61, Issue 5, 2002, Pages 1911-1922

  Hruska, Keith A ^a  

^a MPRB Building ^*  (United States)

Author keywords

BMP 7; Obstructive uropathy; OP 1; Tubulointerstitial nephritis; Ureteral obstruction

Indexed keywords

CITRATE POTASSIUM; ENALAPRIL; LOPERAMIDE; MESALAZINE; OSTEOGENIC PROTEIN 1; TIOPRONIN;

CLINICAL FEATURE; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; CROHN DISEASE; CRYSTALLURIA; CYSTINURIA; DISEASE COURSE; DRUG MECHANISM; ENZYME INHIBITION; GLOMERULUS FILTRATION RATE; HUMAN; HYPERTENSION; INTERSTITIAL NEPHRITIS; NEPHROLITHIASIS; NONHUMAN; OBSTRUCTIVE UROPATHY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEINURIA; PYURIA; REVIEW; RISK; URETER STONE;

EID: 0036238022     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2002.00331.x     Document Type: Article

References (52)

1. Nephrolithiasis
2. Genomic organization of a human cystine transporter gene (SLC3A1) and identifica-tion of novel mutations causing cystinuria
3. Nephrology Forum: Obstructive nephropathy
4. Tubulointerstitial changes as a major determinant in the progression of renal damage
5. Unilateral obstructive nephropathy in the rabbit. I. Early morphologic, physiologic, and histological changes
6. Unilateral obstructive nephropathy in the rabbit. II. Late morphologic changes
7. Interstitial fibrosis in obstructive neophropathy
8. Chronic tubulointerstitial nephropathies
9. Ultrastructural analysis of human proximal tubules and cortical interstitium in chronic renal disease (hydronephrosis)
10. Mechanisms of progressive glomerulosclerosis and tubulointerstitial fibrosis
11. Role of increased glomerular protein traffic in the progression of renal failure
12. The role of lipids in nephrosclerosis and glomerulosclerosis
13. Interstitial inflammation and fibrosis in rats with diet-induced hypercholesterolemia
14. Angiotensin II and gene expression in the kidney
15. Macrophages, monocyte peptide-1, and TGF-β1 in experimental hydronephrosis
16. Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice
17. Upregulation of renin-angiotensin system and downregulation of kallikrein in obstructive nephropathy
18. Regulation of angiotensin II AT1 and AT2 receptors in neonatal ureteral obstruction
19. Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed kidney
20. Delayed treatment with enalapril halts tubulointerstitial fibrosis in rats
21. Osteogenic protein-1 (OP-1) prevents renal fibrogenesis associated with ureteral obstruction
22. Origin of the rat mesangial phagocyte and its expression of leukocyte common antigen
23. Immunological aspects of acute ureteral obstruction: Immune cell infiltrate in the kidney
24. Renal cortical release of a specific macrophage chemoattractant in response to ureteral obstruction
25. Increased expression of TGF- β1 mRNA in the obstructed kidney of rats with unilateral ligation
26. Early and persistent upregulated expression of renal cortical osteopontin in experimental hydronephrosis
27. Bone morphogenetic protein-7 (BMP-7) improves renal fibrosis and accelerates the return of renal function
28. Mechanisms of tubulointerstitial fibrosis
29. Angiotensin II receptor antagonist ameliorates renal tubulointerstitial fibrosis caused by unilateral ureteral ligation
30. Myofibroblasts in experimental hydronephrosis
31. Role of angiotensin II in the tubulointerstitial fibrosis of obstructive nephropathy
32. Regulation of renin-angiotensin system in unilateral ureteral obstruction
33. Transforming growth factor β
34. Transforming growth factor β in disease: The dark side of tissue repair
35. Latent transforming growth factor β: Structural features and mechanisms of activation
36. Increased expression of decorin in experimental hydronephrosis
37. The integrin αvβ6 binds and activates latent TGF-31: A mechanism for regulating pulmonary inflammation and fibrosis
38. Transforming growth factor-β in tissue fibrosis
39. BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning
40. Induction of nephrogenic mesenchyme by osteogenic protein 1 (bone morpho-genetic protein 7)
41. Osteogenic protein- 1 is required for mammalian eye development
42. Expression pattern of osteogenic protein-1 (bone morphogenetic protein-7) in human and mouse development
43. The transforming growth factor-β family
44. Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney
45. Murine osteogenic protein 1 (OP)-1: High levels of mRNA in kidney
46. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye
47. Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat
48. Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines
49. Recovery following relief of unilateral ureteral obstruction in the neonatal rat
50. Cell apoptosis and proliferation in obstructive uropathy
51. Epstein-Barr virus infection of renal proximal tubule cells: Possible role in chronic interstitial nephritis
52. Comparative study of ACE inhibitors and angiotensin II receptor antagonist in interstitial scarring