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Volumn 66, Issue 2, 2004, Pages 597-604

Smad3 deficiency attenuates renal fibrosis, inflammation, and apoptosis after unilateral ureteral obstruction

Author keywords

Apoptosis; Fibrosis; Inflammation; Smad; UUO

Indexed keywords

ANILINE; CD4 ANTIGEN; CD8 ANTIGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DNA NUCLEOTIDYLEXOTRANSFERASE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 3242797424     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2004.00779.x     Document Type: Article
Times cited : (187)

References (34)
  • 2
    • 0030419494 scopus 로고    scopus 로고
    • Molecular insight into renal interstitial fibrosis
    • EDDY AA: Molecular insight into renal interstitial fibrosis. J Am Soc Nephrol 7:2945-2508, 1996
    • (1996) J Am Soc Nephrol , vol.7 , pp. 2945-12508
    • Eddy, A.A.1
  • 4
    • 0026736790 scopus 로고
    • Renal growth factor expression during the early phase of experimental hydronephrosis
    • WALTON G, BUTTYAN R, GARCIA ME, et al: Renal growth factor expression during the early phase of experimental hydronephrosis. J Urol 148:510-514, 1992
    • (1992) J Urol , vol.148 , pp. 510-514
    • Walton, G.1    Buttyan, R.2    Garcia, M.E.3
  • 5
    • 0028335995 scopus 로고
    • Macrophages, monocyte chemoattractant peptide-1, and TGF-β1 in experimental hydronephrosis
    • DIAMOND JR, KEES FD, DING G, et al: Macrophages, monocyte chemoattractant peptide-1, and TGF-β1 in experimental hydronephrosis. Am J Physiol Renal Fluid Electrolyte Physiol 266:F874-F881, 1993
    • (1993) Am J Physiol Renal Fluid Electrolyte Physiol , vol.266
    • Diamond, J.R.1    Kees, F.D.2    Ding, G.3
  • 6
    • 0027165757 scopus 로고
    • Increased expression of TGF-β1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation
    • KANETO H, MORRISSEY J, KLAHR S: Increased expression of TGF-β1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation. Kidney Int 44:313-321, 1993
    • (1993) Kidney Int , vol.44 , pp. 313-321
    • Kaneto, H.1    Morrissey, J.2    Klahr, S.3
  • 7
    • 0032540207 scopus 로고    scopus 로고
    • Transforming growth factor-β receptor type I and II are expressed in renal tubules and are increased after chronic unilateral ureteral obstruction
    • SUTARIA PM, OHEBSHALOM M, MCCAFFREY TA, et al: Transforming growth factor-β receptor type I and II are expressed in renal tubules and are increased after chronic unilateral ureteral obstruction. Life Sci 62:1965-1972, 1998
    • (1998) Life Sci , vol.62 , pp. 1965-1972
    • Sutaria, P.M.1    Ohebshalom, M.2    McCaffrey, T.A.3
  • 8
    • 0033667371 scopus 로고    scopus 로고
    • Antibody to transforming growth factor-β ameliorates tubular apoptosis in unilateral ureteral obstruction
    • MIYAJIMA A, CHEN J, LAWRENCE C, et al: Antibody to transforming growth factor-β ameliorates tubular apoptosis in unilateral ureteral obstruction. Kidney Int 58:2301-2313, 2000
    • (2000) Kidney Int , vol.58 , pp. 2301-2313
    • Miyajima, A.1    Chen, J.2    Lawrence, C.3
  • 9
    • 0033736396 scopus 로고    scopus 로고
    • Transforming growth factor-β1 antisense oligonucleotides block interstitial fibrosis in unilateral ureteral obstruction
    • ISAKA Y, TSUJIE M, ANDO Y, et al: Transforming growth factor-β1 antisense oligonucleotides block interstitial fibrosis in unilateral ureteral obstruction. Kidney Int 58:1885-1892, 2000
    • (2000) Kidney Int , vol.58 , pp. 1885-1892
    • Isaka, Y.1    Tsujie, M.2    Ando, Y.3
  • 10
    • 0034819690 scopus 로고    scopus 로고
    • Quantification of TGF-β1 mRNA along rat nephron in obstructive nephropathy
    • FUKUDA K, YOSHITOMI K, YANAGIDA T, et al: Quantification of TGF-β1 mRNA along rat nephron in obstructive nephropathy. Am J Physiol Renal Physiol 281:F513-F521, 2001
    • (2001) Am J Physiol Renal Physiol , vol.281
    • Fukuda, K.1    Yoshitomi, K.2    Yanagida, T.3
  • 11
    • 0028109801 scopus 로고
    • Transforming growth factor-β in tissue fibrosis
    • BORDER W, NOBLE N: Transforming growth factor-β in tissue fibrosis. N Engl J Med 331:1286-1292, 1994
    • (1994) N Engl J Med , vol.331 , pp. 1286-1292
    • Border, W.1    Noble, N.2
  • 13
    • 0036277026 scopus 로고    scopus 로고
    • Myofibroblasts and mechanoregulaton of connective tissue remodeling
    • TOMASEK JJ, GABBIANI G, HINZ B, et al: Myofibroblasts and mechanoregulaton of connective tissue remodeling. Nature Rev Mol Cell Biol 3:349-363, 2002
    • (2002) Nature Rev Mol Cell Biol , vol.3 , pp. 349-363
    • Tomasek, J.J.1    Gabbiani, G.2    Hinz, B.3
  • 14
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signaling from cell membrane to nucleus through Smad proteins
    • HELDIN CH, MIYAZONO K, TEN DIJKE P: TGF-β signaling from cell membrane to nucleus through SMAD proteins. Nature 390:465-471, 1997
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 15
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-β signals
    • MASSAGUE J: How cells read TGF-β signals. Nat Rev Mol Cell Biol 1:169-178, 2000
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 169-178
    • Massague, J.1
  • 16
    • 0034104591 scopus 로고    scopus 로고
    • Smads as transcriptional co-modulators
    • ATTISANO L, WARANA JL: Smads as transcriptional co-modulators. Curr Opin Cell Biol 12:235-243, 2000
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 235-243
    • Attisano, L.1    Warana, J.L.2
  • 17
    • 0033104503 scopus 로고    scopus 로고
    • Targeted disruption of Smad3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β
    • YANG X, LETTERIO JJ, LECHLEIDER RJ, et al: Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β. EMBO J 18:1280-1291, 1999
    • (1999) EMBO J , vol.18 , pp. 1280-1291
    • Yang, X.1    Letterio, J.J.2    Lechleider, R.J.3
  • 18
    • 0032934979 scopus 로고    scopus 로고
    • Targeted disruption of Smad3 reveals an essential role in transforming growth factor-β-mediated signal transduction
    • DATTO MB, FREDERICK JP, PAN L, et al: Targeted disruption of Smad3 reveals an essential role in transforming growth factor-β-mediated signal transduction. Mol Cell Biol 19:2495-2504, 1999
    • (1999) Mol Cell Biol , vol.19 , pp. 2495-2504
    • Datto, M.B.1    Frederick, J.P.2    Pan, L.3
  • 19
    • 0032544448 scopus 로고    scopus 로고
    • Smad3 mutant mice develop metastatic colorectal cancer
    • ZHU Y, RICHARDSON JA, PARADA LF, et al: Smad3 mutant mice develop metastatic colorectal cancer. Cell 94:703-714, 1998
    • (1998) Cell , vol.94 , pp. 703-714
    • Zhu, Y.1    Richardson, J.A.2    Parada, L.F.3
  • 20
    • 0032565859 scopus 로고    scopus 로고
    • Smad2 role in mesoderm formation, left-right patterning, and craniofacial development
    • NOMURA M, LI E: Smad2 role in mesoderm formation, left-right patterning, and craniofacial development. Nature 393:786-790, 1998
    • (1998) Nature , vol.393 , pp. 786-790
    • Nomura, M.1    Li, E.2
  • 21
    • 0032549806 scopus 로고    scopus 로고
    • Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo
    • WALDRIP WR, BIKOFF EK, HOODLESS PA, et al: Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo. Cell 92:797-808, 1998
    • (1998) Cell , vol.92 , pp. 797-808
    • Waldrip, W.R.1    Bikoff, E.K.2    Hoodless, P.A.3
  • 22
    • 0032482751 scopus 로고    scopus 로고
    • Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor Smad2
    • WEINSTEIN M, YANG X, Li C, et al: Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor Smad2. Proc Natl Acad Sci USA 95:9378-9383, 1998
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9378-9383
    • Weinstein, M.1    Yang, X.2    Li, C.3
  • 23
    • 0037566734 scopus 로고    scopus 로고
    • Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy
    • FUJIMOTO M, MAEZAWA Y, YOKOTE K, et al: Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy. Biochem Biophys Res Commun 305:1002-1007, 2003
    • (2003) Biochem Biophys Res Commun , vol.305 , pp. 1002-1007
    • Fujimoto, M.1    Maezawa, Y.2    Yokote, K.3
  • 24
    • 0034912450 scopus 로고    scopus 로고
    • PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction
    • ODA T, JUNG YO, KIM HS, et al: PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction. Kidney Int 30:587-596, 2001
    • (2001) Kidney Int , vol.30 , pp. 587-596
    • Oda, T.1    Jung, Y.O.2    Kim, H.S.3
  • 25
    • 0036177427 scopus 로고    scopus 로고
    • Transforming growth factor-β signaling through the Smad pathway: Role in extracellular matrix gene expression and regulation
    • VERRECCHIA F, MAUVIL A: Transforming growth factor-β signaling through the Smad pathway: Role in extracellular matrix gene expression and regulation. J Invest Dermatol 118:211-215, 2002
    • (2002) J Invest Dermatol , vol.118 , pp. 211-215
    • Verrecchia, F.1    Mauvil, A.2
  • 26
    • 0042831330 scopus 로고    scopus 로고
    • Smad3 mediates transforming growth factor-β induced α-smooth muscle actin expression
    • HU B, WU Z, PHAM SH: Smad3 mediates transforming growth factor-β induced α-smooth muscle actin expression. Am J Resp Cell Mol Biol 29:397-404, 2003
    • (2003) Am J Resp Cell Mol Biol , vol.29 , pp. 397-404
    • Hu, B.1    Wu, Z.2    Pham, S.H.3
  • 27
    • 0033195998 scopus 로고    scopus 로고
    • Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response
    • ASHCROFT GS, YANG X, GLICK AB, et al: Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response. Nat Cell Biol 1:260-266, 1999
    • (1999) Nat Cell Biol , vol.1 , pp. 260-266
    • Ashcroft, G.S.1    Yang, X.2    Glick, A.B.3
  • 28
    • 0036256156 scopus 로고    scopus 로고
    • Smad3 in the mammary epithelium has a nonredundant role in the induction of apoptosis, but not in the regulation of proliferation or differentiation by transforming growth factor-β
    • YANG YA, TANG B, ROBINSON G, et al: Smad3 in the mammary epithelium has a nonredundant role in the induction of apoptosis, but not in the regulation of proliferation or differentiation by transforming growth factor-β. Cell Growth Differ 13:123-130, 2002
    • (2002) Cell Growth Differ , vol.13 , pp. 123-130
    • Yang, Y.A.1    Tang, B.2    Robinson, G.3
  • 29
    • 0037437371 scopus 로고    scopus 로고
    • TGF-β1-mediated fibroblast-myofibroblast terminal differentiation - The role of Smad proteins
    • EVANS RA, TIAN YC, STEADMAN R, PHILIPS AO: TGF-β1-mediated fibroblast-myofibroblast terminal differentiation-the role of Smad proteins. Exp Cell Res 282:90-100, 2003
    • (2003) Exp Cell Res , vol.282 , pp. 90-100
    • Evans, R.A.1    Tian, Y.C.2    Steadman, R.3    Philips, A.O.4
  • 30
    • 0031944290 scopus 로고    scopus 로고
    • Regulation of immune responses by TGF-β
    • LETTERIO JJ, ROBERTS AB: Regulation of immune responses by TGF-β. Annu Rev Immunol 16:137-154, 1998
    • (1998) Annu Rev Immunol , vol.16 , pp. 137-154
    • Letterio, J.J.1    Roberts, A.B.2
  • 31
    • 0037849935 scopus 로고    scopus 로고
    • Transforming growth factor-β1 potentiates renal tubular epithelial death by a mechanism independent of Smad signaling
    • DAI C, YANG J, LIU Y: Transforming growth factor-β1 potentiates renal tubular epithelial death by a mechanism independent of Smad signaling. J Biol Chem 278:12537-12545, 2003
    • (2003) J Biol Chem , vol.278 , pp. 12537-12545
    • Dai, C.1    Yang, J.2    Liu, Y.3
  • 32
    • 0035070420 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy
    • MIZUNO S, MATSUMOTO K, NAKAMURA T: Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy. Kidney Int 59:1304-1314, 2001
    • (2001) Kidney Int , vol.59 , pp. 1304-1314
    • Mizuno, S.1    Matsumoto, K.2    Nakamura, T.3
  • 33
    • 0037498439 scopus 로고    scopus 로고
    • Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model
    • LAN HY, MU W, TOMITA N, et al: Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol 14:1535-1548, 2003
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1535-1548
    • Lan, H.Y.1    Mu, W.2    Tomita, N.3
  • 34
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • SATO M, MURAGAKI Y, SAIKA S, et al: Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112:1486-1494, 2003
    • (2003) J Clin Invest , vol.112 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.