TGF-β1 siRNA suppresses the tubulointerstitial fibrosis in the kidney of ureteral obstruction

Experimental and Molecular Pathology

Volumn 81, Issue 1, 2006, Pages 48-54

  Hwang, Meeyul ^a   Kim, Hye Jin ^a   Noh, Hey Jeong ^a   Chang, Young Chae ^a   Chae, Young Mi ^a   Kim, Kyung Hyun ^a   Jeon, Jae Pil ^b   Lee, Tae Sung ^a   Oh, Hoon Kyu ^a   Lee, Yun Sik ^c   Park, Kwan Kyu ^a  

^a The Catholic University of Korea   (South Korea)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Gene therapy; siRNA; TGF 1; Tubulointerstitial fibrosis; Unilateral ureteral obstruction (UUO)

Indexed keywords

COLLAGEN TYPE 1; GLUCOSE; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; TGFB1 PROTEIN, MOUSE; TGFB1 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPRESSION VECTOR; GENE REPRESSION; GENE TARGETING; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; KIDNEY CELL CULTURE; KIDNEY FIBROSIS; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; RNA INTERFERENCE; RNA VECTOR; TRANSCRIPTION TERMINATION; URETER OBSTRUCTION; ANIMAL; DRUG ANTAGONISM; FIBROSIS; GENE THERAPY; GENE VECTOR; GENETICS; KIDNEY DISEASE; KIDNEY TUBULE; MESANGIUM; METABOLISM; PATHOLOGY; RAT;

ANIMALS; FIBROSIS; GENE THERAPY; GENETIC VECTORS; GLOMERULAR MESANGIUM; GLUCOSE; KIDNEY DISEASES; KIDNEY TUBULES; MICE; RATS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; URETERAL OBSTRUCTION;

EID: 33745350487     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2005.11.005     Document Type: Article

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