Suppression of PAI-1 expression through inhibition of the EGFR-mediated signaling cascade in rat kidney fibroblast by ascofuranone

Journal of Cellular Biochemistry

Volumn 107, Issue 2, 2009, Pages 335-344

  Cho, Hyun Ji ^a,b   Kang, Jeong Han ^a   Kim, Teoan ^a   Park, Kwang Kyun ^c   Kim, Cheorl Ho ^d   Lee, In Seon ^e   Min, Kwan Sik ^f   Magae, Junji ^g   Nakajima, Hiroo ^h   Bae, Young Seuk ^b   Chang, Young Chae ^a  

^a The Catholic University of Korea   (South Korea)

^b Kyungpook National University   (South Korea)

^c Yonsei University College of Dentistry   (South Korea)

^d Sungkyunkwan University   (South Korea)

^e Keimyung University   (South Korea)

^f Hankyong National University   (South Korea)

^g CENTRAL RESEARCH INSTITUTE OF ELECTRIC POWER INDUSTRY   (Japan)

^h KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Ascofuranone; Epidermal growth factor receptor; Fibrosis; HB EGF; Plasminogen activator inhibitor 1; Renal fibroblast

Indexed keywords

ANTIFIBROTIC AGENT; ASCOFURANONE; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE A; GELATINASE B; ISOPRENOID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PHOSPHOTRANSFERASE INHIBITOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; RAF PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME INHIBITION; FIBROBLAST; GENE EXPRESSION REGULATION; KIDNEY CELL; KIDNEY FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BLOTTING, WESTERN; FIBROBLASTS; GENE EXPRESSION; KIDNEY; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE INHIBITORS; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SESQUITERPENES; SIGNAL TRANSDUCTION; TERPENES;

RATTUS;

EID: 66149118892     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22130     Document Type: Article

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