Absence of Smad3 confers radioprotection through modulation of ERK-MAPK in primary dermal fibroblasts

Journal of Dermatological Science

Volumn 48, Issue 1, 2007, Pages 35-42

  Arany, Praveen R ^a   Flanders, Kathleen C ^a   DeGraff, William ^a   Cook, John ^a   Mitchell, James B ^a   Roberts, Anita B ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Fibrosis; Ionizing radiation; Radioprotection; Smad3; Transforming growth factor beta

Indexed keywords

HISTONE H2AX; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P53; SMAD3 PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENETIC TRANSFECTION; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IONIZING RADIATION; KNOCKOUT MOUSE; MODULATION; MOLECULAR DYNAMICS; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RADIATION DOSE; RADIATION PROTECTION; REPORTER GENE; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; WESTERN BLOTTING;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; DERMIS; DNA DAMAGE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HISTONES; MICE; MICE, KNOCKOUT; RADIATION INJURIES; RADIATION, IONIZING; SMAD3 PROTEIN; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34548009590     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2007.05.012     Document Type: Article

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