Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age

PLoS Biology

Volumn 8, Issue 5, 2010, Pages

  Kauffman, Amanda L ^a   Ashraf, Jasmine M ^a   orces Zimmerman, M Ryan ^a   Landis, Jessica N ^a   Murphy, Coleen T ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INSULIN; MUTANT PROTEIN; PROTEIN CRH 1; PROTEIN DAF 2; PROTEIN EAT 2; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; DAF 2 PROTEIN, C ELEGANS; DAF-2 PROTEIN, C ELEGANS; EAT 2 PROTEIN, C ELEGANS; EAT-2 PROTEIN, C ELEGANS; INSULIN RECEPTOR; NICOTINIC RECEPTOR; SOMATOMEDIN C;

ADULTHOOD; AGING; ARTICLE; ASSOCIATIVE MEMORY; CAENORHABDITIS ELEGANS; COGNITION; CONTROLLED STUDY; DIET RESTRICTION; INSULIN METABOLISM; LEARNING DISORDER; LONG TERM MEMORY; MEMORY DISORDER; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; ANIMAL BEHAVIOR; ANIMAL FOOD; CHEMOTAXIS; GENETICS; HUMAN; LEARNING; MEMORY; METABOLISM; MUTATION; PHYSIOLOGY;

CAENORHABDITIS ELEGANS;

AGING; ANIMAL FEED; ANIMALS; ASSOCIATION LEARNING; BEHAVIOR, ANIMAL; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CHEMOTAXIS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; HUMANS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LEARNING; MEMORY; MUTATION; RECEPTOR, INSULIN; RECEPTORS, NICOTINIC; SIGNAL TRANSDUCTION;

EID: 77952923018     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1000372     Document Type: Article

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