-
1
-
-
77955058763
-
The role of traditional Chinese herbal medicines in cancer therapy from TCM theory to mechanistic insights
-
Hsiao W. L. W., Liu L., The role of traditional Chinese herbal medicines in cancer therapy from TCM theory to mechanistic insights Planta Medica 2010 76 11 1118 1131
-
(2010)
Planta Medica
, vol.76
, Issue.11
, pp. 1118-1131
-
-
Hsiao, W.L.W.1
Liu, L.2
-
2
-
-
0035315838
-
The anti-malarial artesunate is also active against cancer
-
Efferth T., Dunstan H., Sauerbrey A., Miyachi H., Chitambar C. R., The anti-malarial artesunate is also active against cancer International Journal of Oncology 2001 18 4 767 773
-
(2001)
International Journal of Oncology
, vol.18
, Issue.4
, pp. 767-773
-
-
Efferth, T.1
Dunstan, H.2
Sauerbrey, A.3
Miyachi, H.4
Chitambar, C.R.5
-
3
-
-
0027267309
-
Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells
-
Woerdenbag H. J., Moskal T. A., Pras N., Malingré T. M., El-Feraly F. S., Kampinga H. H., Konings A. W. T., Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells Journal of Natural Products 1993 56 6 849 856 (Pubitemid 23195612)
-
(1993)
Journal of Natural Products (Lloydia)
, vol.56
, Issue.6
, pp. 849-856
-
-
Woerdenbag, H.J.1
Moskal, T.A.2
Pras, N.3
Malingre, T.M.4
El-Feraly, F.S.5
Kampinga, H.H.6
Konings, A.W.T.7
-
4
-
-
1842856050
-
Modulation of multidrug resistance by artemisinin, artesunate and dihydroartemisinin in K562/adr and GLC4/adr resistant cell lines
-
DOI 10.1248/bpb.25.1555
-
Reungpatthanaphong P., Mankhetkorn S., Modulation of multidrug resistance by artemisinin, artesunate and dihydroartemisinin in K562/adr and GLC4/adr resistant cell lines Biological and Pharmaceutical Bulletin 2002 25 12 1555 1561 (Pubitemid 39663669)
-
(2002)
Biological and Pharmaceutical Bulletin
, vol.25
, Issue.12
, pp. 1555-1561
-
-
Reungpatthanaphong, P.1
Mankhetkorn, S.2
-
5
-
-
0042844638
-
Molecular modes of action of artesunate in tumor cell lines
-
DOI 10.1124/mol.64.2.382
-
Efferth T., Saverbrey A., Olbrich A., Molecular modes of action of artesunate in tumour cell lines Molecular Pharmacology 2003 64 2 382 394 (Pubitemid 36910002)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.2
, pp. 382-394
-
-
Efferth, T.1
Sauerbrey, A.2
Olbrich, A.3
Gebhart, E.4
Rauch, P.5
Weber, H.O.6
Hengstler, J.G.7
Halatsch, M.-E.8
Volm, M.9
Tew, K.D.10
Ross, D.D.11
Funk, J.O.12
-
6
-
-
1642482269
-
Artemisinin derivatives: Toxic for laboratory animals, safe for humans?
-
DOI 10.1016/j.toxlet.2003.12.009
-
Gordi T., Lepist E. I., Artemisinin derivatives: toxic for laboratory animals, safe for humans? Toxicology Letters 2004 147 2 99 107 (Pubitemid 38130178)
-
(2004)
Toxicology Letters
, vol.147
, Issue.2
, pp. 99-107
-
-
Gordi, T.1
Lepist, E.-I.2
-
7
-
-
68049123592
-
Artemisinin resistance in Plasmodium falciparum malaria
-
Dondorp A. M., Nosten F., Yi P., Das D., Phyo A. P., Tarning J., Lwin K. M., Ariey F., Hanpithakpong W., Lee S. J., Ringwald P., Silamut K., Imwong M., Chotivanich K., Lim P., Herdman T., An S. S., Yeung S., Singhasivanon P., Day N. P. J., Lindegardh N., Socheat D., White N. J., Artemisinin resistance in Plasmodium falciparum malaria New England Journal of Medicine 2009 361 5 455 467
-
(2009)
New England Journal of Medicine
, vol.361
, Issue.5
, pp. 455-467
-
-
Dondorp, A.M.1
Nosten, F.2
Yi, P.3
Das, D.4
Phyo, A.P.5
Tarning, J.6
Lwin, K.M.7
Ariey, F.8
Hanpithakpong, W.9
Lee, S.J.10
Ringwald, P.11
Silamut, K.12
Imwong, M.13
Chotivanich, K.14
Lim, P.15
Herdman, T.16
An, S.S.17
Yeung, S.18
Singhasivanon, P.19
Day, N.P.J.20
Lindegardh, N.21
Socheat, D.22
White, N.J.23
more..
-
8
-
-
0018612308
-
Antimalaria studies on Qinghaosu
-
Qinghaosu Antimalaria Coordinating Research Group
-
Qinghaosu Antimalaria Coordinating Research Group, Antimalaria studies on Qinghaosu Chinese Medical Journal 1979 92 12 811 816
-
(1979)
Chinese Medical Journal
, vol.92
, Issue.12
, pp. 811-816
-
-
-
9
-
-
0031954715
-
Artemisinin kinetics and dynamics during oral and rectal treatment of uncomplicated malaria
-
DOI 10.1016/S0009-9236(98)90044-3
-
Ashton M., Sy N. D., van Huong N., Gordi T., Hai T. N., Huong D. X., Niu N. T., Cng L. D., Artemisinin kinetics and dynamics during oral and rectal treatment of uncomplicated malaria Clinical Pharmacology and Therapeutics 1998 63 4 482 493 (Pubitemid 28214972)
-
(1998)
Clinical Pharmacology and Therapeutics
, vol.63
, Issue.4
, pp. 482-493
-
-
Ashton, M.1
Sy, N.D.2
Van Huong, N.3
Gordi, T.4
Hai, T.N.5
Huong, D.X.6
Nieu, N.T.7
Cong, L.D.8
-
10
-
-
70349736921
-
Pharmacokinetic and pharmacodynamic profiles of rapid-acting artemisinins in the antimalarial therapy
-
Li Q., Weina P. J., Milhous W. K., Pharmacokinetic and pharmacodynamic profiles of rapid-acting artemisinins in the antimalarial therapy Current Drug Therapy 2007 2 3 210 223
-
(2007)
Current Drug Therapy
, vol.2
, Issue.3
, pp. 210-223
-
-
Li, Q.1
Weina, P.J.2
Milhous, W.K.3
-
11
-
-
0036149009
-
C-10 ester and ether derivatives of dihydroartemisinin - 10- artesunate, preparation of authentic 10- artesunate, and of other ester and ether derivatives bearing potential aromatic intercalating groups at C-10
-
Haynes R. K., Chan H. W., Cheung M. K., Lam W. L., Soo M. K., Tsang H. W., Voerste A., Williams I. D., C-10 ester and ether derivatives of dihydroartemisinin-10- artesunate, preparation of authentic 10- artesunate, and of other ester and ether derivatives bearing potential aromatic intercalating groups at C-10 European Journal of Organic Chemistry 2002 2002 1 113 132
-
(2002)
European Journal of Organic Chemistry
, vol.2002
, Issue.1
, pp. 113-132
-
-
Haynes, R.K.1
Chan, H.W.2
Cheung, M.K.3
Lam, W.L.4
Soo, M.K.5
Tsang, H.W.6
Voerste, A.7
Williams, I.D.8
-
12
-
-
0021948029
-
Qinghaosu (Artemisinin): An antimalarial drug from China
-
Klayman D. L., Qinghaosu (artemisinin): an antimalarial drug from China Science 1985 228 4703 1049 1055 (Pubitemid 15227365)
-
(1985)
Science
, vol.228
, Issue.4703
, pp. 1049-1055
-
-
Klayman, D.L.1
-
13
-
-
33646158237
-
From artemisinin to new artemisinin antimalarials: Biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements
-
Haynes R. K., From artemisinin to new artemisinin antimalarials: biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements Current Topics in Medicinal Chemistry 2006 6 5 509 537
-
(2006)
Current Topics in Medicinal Chemistry
, vol.6
, Issue.5
, pp. 509-537
-
-
Haynes, R.K.1
-
14
-
-
42049102584
-
Relationship between antimalarial activity and heme alkylation for spiro- and dispiro-1,2,4-trioxolane antimalarials
-
DOI 10.1128/AAC.01033-07
-
Creek D. J., Charman W. N., Chiu F. C. K., Prankerd R. J., Dong Y., Vennerstrom J. L., Charman S. A., Relationship between antimalarial activity and heme alkylation for spiro- and dispiro-1,2,4-trioxolane antimalarials Antimicrobial Agents and Chemotherapy 2008 52 4 1291 1296 (Pubitemid 351521990)
-
(2008)
Antimicrobial Agents and Chemotherapy
, vol.52
, Issue.4
, pp. 1291-1296
-
-
Creek, D.J.1
Charman, W.N.2
Chiu, F.C.K.3
Prankerd, R.J.4
Dong, Y.5
Vennerstrom, J.L.6
Charman, S.A.7
-
15
-
-
34249012765
-
New developments in synthetic peroxidic drugs as artemisinin mimics
-
DOI 10.1016/j.drudis.2007.04.009, PII S1359644607001870
-
Jefford C. W., New developments in synthetic peroxidic drugs as artemisinin mimics Drug Discovery Today 2007 12 11-12 487 495 (Pubitemid 46783690)
-
(2007)
Drug Discovery Today
, vol.12
, Issue.11-12
, pp. 487-495
-
-
Jefford, C.W.1
-
16
-
-
60849089373
-
Preparation of bicyclic 1,2,4-trioxanes from , -unsaturated ketones
-
Ramirez A. P., Thomas A. M., Woerpel K. A., Preparation of bicyclic 1,2,4-trioxanes from, -unsaturated ketones Organic Letters 2009 11 3 507 510
-
(2009)
Organic Letters
, vol.11
, Issue.3
, pp. 507-510
-
-
Ramirez, A.P.1
Thomas, A.M.2
Woerpel, K.A.3
-
17
-
-
12144289907
-
Novel Endoperoxide Antimalarials: Synthesis, Heme Binding, and Antimalarial Activity
-
DOI 10.1021/jm0305319
-
Taylor D. K., Avery T. D., Greatrex B. W., Tiekink E. R. T., Macreadie I. G., Macreadie P. I., Humphries A. D., Kalkanidis M., Fox E. N., Klonis N., Tilley L., Novel endoperoxide antimalarials: synthesis, heme binding, and antimalarial activity Journal of Medicinal Chemistry 2004 47 7 1833 1839 (Pubitemid 38380927)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.7
, pp. 1833-1839
-
-
Taylor, D.K.1
Avery, T.D.2
Greatrex, B.W.3
Tiekink, E.R.T.4
Macreadie, I.G.5
Macreadie, P.I.6
Humphries, A.D.7
Kalkanidis, M.8
Fox, E.N.9
Klonis, N.10
Tilley, L.11
-
18
-
-
0024458691
-
Synthesis of tricyclic arteannuin-like compounds
-
DOI 10.1016/S0040-4039(01)80724-3
-
Jefford C. W., Velarde J., Bernardinelli G., Synthesis of tricyclic arteannuin-like compounds Tetrahedron Letters 1989 30 34 4485 4488 (Pubitemid 19223669)
-
(1989)
Tetrahedron Letters
, vol.30
, Issue.34
, pp. 4485-4488
-
-
Jefford, C.W.1
Velarde, J.2
Bernardinelli, G.3
-
19
-
-
0026635291
-
Extraordinarily potent antimalarial compounds: New, structurally simple, easily synthesized, tricyclic 1,2,4-trioxanes
-
Posner G. H., Chang Ho Oh, Gerena L., Milhous W. K., Extraordinarily potent antimalarial compounds: new, structurally simple, easily synthesized, tricyclic 1,2,4-trioxanes Journal of Medicinal Chemistry 1992 35 13 2459 2467
-
(1992)
Journal of Medicinal Chemistry
, vol.35
, Issue.13
, pp. 2459-2467
-
-
Posner, G.H.1
Ho Oh, C.2
Gerena, L.3
Milhous, W.K.4
-
20
-
-
0026014249
-
Artemisinin (qinghaosu): The role of intracellular hemin in its mechanism of antimalarial action
-
Meshnick S. R., Thomas A., Ranz A., Xu C. M., Pan H. Z., Artemisinin (qinghaosu): the role of intracellular hemin in its mechanism of antimalarial action Molecular and Biochemical Parasitology 1991 49 2 181 189
-
(1991)
Molecular and Biochemical Parasitology
, vol.49
, Issue.2
, pp. 181-189
-
-
Meshnick, S.R.1
Thomas, A.2
Ranz, A.3
Xu, C.M.4
Pan, H.Z.5
-
21
-
-
0035005885
-
Possible modes of action of the artemisinin-type compounds
-
DOI 10.1016/S1471-4922(00)01838-9, PII S1471492200018389
-
Olliaro P. L., Haynes R. K., Meunier B., Yuthavong Y., Possible modes of action of the artemisinin-type compounds Trends in Parasitology 2001 17 3 122 126 (Pubitemid 32422178)
-
(2001)
Trends in Parasitology
, vol.17
, Issue.3
, pp. 122-126
-
-
Olliaro, P.L.1
Haynes, R.K.2
Meunier, B.3
Yuthavong, Y.4
-
22
-
-
77950362015
-
The molecular mechanism of action of artemisininthe debate continues
-
O'Neill P. M., Barton V. E., Ward S. A., The molecular mechanism of action of artemisininthe debate continues Molecules 2010 15 3 1705 1721
-
(2010)
Molecules
, vol.15
, Issue.3
, pp. 1705-1721
-
-
O'Neill, P.M.1
Barton, V.E.2
Ward, S.A.3
-
23
-
-
79960992639
-
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion
-
Klonis N., Crespo-Ortiz M. P., Bottova I., Abu-Bakar N., Kenny S., Rosenthal P. J., Tilley L., Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion Proceedings of the National Academy of Sciences of the United States of America 2011 108 28 11405 11410
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.28
, pp. 11405-11410
-
-
Klonis, N.1
Crespo-Ortiz, M.P.2
Bottova, I.3
Abu-Bakar, N.4
Kenny, S.5
Rosenthal, P.J.6
Tilley, L.7
-
24
-
-
0036637504
-
Ultrastructural alterations in adult Schistosoma mansoni caused by artemether
-
Shuhua X., Binggui S., Utzinger J., Chollet J., Tanner M., Ultrastructural alterations in adult Schistosoma mansoni caused by artemether Memorias do Instituto Oswaldo Cruz 2002 97 5 717 724 (Pubitemid 135746091)
-
(2002)
Memorias do Instituto Oswaldo Cruz
, vol.97
, Issue.5
, pp. 717-724
-
-
Shuhua, X.1
Binggui, S.2
Utzinger, J.3
Chollet, J.4
Tanner, M.5
-
25
-
-
0036180668
-
Deoxyartemisinin derivatives from photooxygenation of anhydrodeoxydihydroartemisinin and their cytotoxic evaluation
-
DOI 10.1021/np0104065
-
Galal A. M., Ross S. A., ElSohly M. A., ElSohly H. N., El-Feraly F. S., Ahmed M. S., McPhail A. T., Deoxyartemisinin derivatives from photooxygenation of anhydrodeoxydihydroartemisinin and their cytotoxic evaluation Journal of Natural Products 2002 65 2 184 188 (Pubitemid 34171179)
-
(2002)
Journal of Natural Products
, vol.65
, Issue.2
, pp. 184-188
-
-
Galal, A.M.1
Ross, S.A.2
ElSohly, M.A.3
ElSohly, H.N.4
El-Feraly, F.S.5
Ahmed, M.S.6
McPhail, A.T.7
-
26
-
-
0031726077
-
Artemisinin-derived sesquiterpene lactones as potential antitumour compounds: Cytotoxic action against bone marrow and tumour cells
-
DOI 10.1055/s-2006-957533
-
Beekman A. C., Wierenga P. K., Woerdenbag H. J., Van Uden W., Pras N., Konings A. W.T., El-Feraly F. S., Galal A. M., Wikstrm H. V., Artemisinin-derived sesquiterpene lactones as potential antitumour compounds: cytotoxic action against bone marrow and tumour cells Planta Medica 1998 64 7 615 619 (Pubitemid 28481473)
-
(1998)
Planta Medica
, vol.64
, Issue.7
, pp. 615-619
-
-
Beekman, A.C.1
Wierenga, P.K.2
Woerdenbag, H.J.3
Van Uden, W.4
Pras, N.5
Konings, A.W.T.6
El-Feraly, F.S.7
Galal, A.M.8
Wikstrom, H.V.9
-
27
-
-
78649251920
-
Heme as trigger and target for trioxane-containing antimalarial drugs
-
Meunier B., Robert A., Heme as trigger and target for trioxane-containing antimalarial drugs Accounts of Chemical Research 2010 43 11 1444 1451
-
(2010)
Accounts of Chemical Research
, vol.43
, Issue.11
, pp. 1444-1451
-
-
Meunier, B.1
Robert, A.2
-
28
-
-
34248229771
-
Evidence for the involvement of carbon-centered radicals in the induction of apoptotic cell death by artemisinin compounds
-
DOI 10.1074/jbc.M610375200
-
Mercer A. E., Maggs J. L., Sun X. M., Cohen G. M., Chadwick J., O'Neill P. M., Park B. K., Evidence for the involvement of carbon-centered radicals in the induction of apoptotic cell death by artemisinin compounds Journal of Biological Chemistry 2007 282 13 9372 9382 (Pubitemid 47104599)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.13
, pp. 9372-9382
-
-
Mercer, A.E.1
Maggs, J.L.2
Sun, X.-M.3
Cohen, G.M.4
Chadwick, J.5
O'Neill, P.M.6
Park, B.K.7
-
29
-
-
70449562761
-
Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target
-
Zhang S., Gerhard G. S., Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target PLoS ONE 2009 4 10
-
(2009)
PLoS ONE
, vol.4
, Issue.10
-
-
Zhang, S.1
Gerhard, G.S.2
-
30
-
-
33644672627
-
Artesunate in the treatment of metastatic uveal melanomafirst experiences
-
Berger T. G., Dieckmann D., Efferth T., Schultz E. S., Funk J. O., Baur A., Schuler G., Artesunate in the treatment of metastatic uveal melanomafirst experiences Oncology Reports 2005 14 6 1599 1603
-
(2005)
Oncology Reports
, vol.14
, Issue.6
, pp. 1599-1603
-
-
Berger, T.G.1
Dieckmann, D.2
Efferth, T.3
Schultz, E.S.4
Funk, J.O.5
Baur, A.6
Schuler, G.7
-
31
-
-
79953194472
-
Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production
-
Hamacher-Brady A., Stein H. A., Turschner S., Toegel I., Mora R., Jennewein N., Efferth T., Eils R., Brady N. R., Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production Journal of Biological Chemistry 2011 286 8 6587 6601
-
(2011)
Journal of Biological Chemistry
, vol.286
, Issue.8
, pp. 6587-6601
-
-
Hamacher-Brady, A.1
Stein, H.A.2
Turschner, S.3
Toegel, I.4
Mora, R.5
Jennewein, N.6
Efferth, T.7
Eils, R.8
Brady, N.R.9
-
32
-
-
4444261942
-
Artemisinin induces apoptosis in human cancer cells
-
Singh N. P., Lai H. C., Artemisinin induces apoptosis in human cancer cells Anticancer Research 2004 24 4 2277 2280 (Pubitemid 39166306)
-
(2004)
Anticancer Research
, vol.24
, Issue.4
, pp. 2277-2280
-
-
Singh, N.P.1
Lai, H.C.2
-
33
-
-
77952266182
-
Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells
-
Lu J. J., Meng L. H., Shankavaram U. T., Zhu C. H., Tong L. J., Chen G., Lin L. P., Weinstein J. N., Ding J., Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells Biochemical Pharmacology 2010 80 1 22 30
-
(2010)
Biochemical Pharmacology
, vol.80
, Issue.1
, pp. 22-30
-
-
Lu, J.J.1
Meng, L.H.2
Shankavaram, U.T.3
Zhu, C.H.4
Tong, L.J.5
Chen, G.6
Lin, L.P.7
Weinstein, J.N.8
Ding, J.9
-
34
-
-
84861595378
-
The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells
-
Lu J. J., Chen S. M., Zhang X. W., Ding J., Meng L. H., The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells Investigational New Drugs 2010 7 1 8
-
(2010)
Investigational New Drugs
, vol.7
, pp. 1-8
-
-
Lu, J.J.1
Chen, S.M.2
Zhang, X.W.3
Ding, J.4
Meng, L.H.5
-
35
-
-
78651404852
-
The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials
-
Mercer A. E., Copple I. M., Maggs J. L., O'Neill P. M., Park B. K., The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials Journal of Biological Chemistry 2011 283 2 987 996
-
(2011)
Journal of Biological Chemistry
, vol.283
, Issue.2
, pp. 987-996
-
-
Mercer, A.E.1
Copple, I.M.2
Maggs, J.L.3
O'Neill, P.M.4
Park, B.K.5
-
36
-
-
0029037444
-
Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin
-
Lai H., Singh N. P., Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin Cancer Letters 1995 91 1 41 46
-
(1995)
Cancer Letters
, vol.91
, Issue.1
, pp. 41-46
-
-
Lai, H.1
Singh, N.P.2
-
37
-
-
71949100459
-
Artemisinin-transferrin conjugate retards growth of breast tumors in the rat
-
Lai H., Nakase I., Lacoste E., Singh N. P., Sasaki T., Artemisinin-transferrin conjugate retards growth of breast tumors in the rat Anticancer Research 2009 29 10 3807 3810
-
(2009)
Anticancer Research
, vol.29
, Issue.10
, pp. 3807-3810
-
-
Lai, H.1
Nakase, I.2
Lacoste, E.3
Singh, N.P.4
Sasaki, T.5
-
38
-
-
40849097597
-
Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugation
-
DOI 10.1016/j.ijpharm.2007.09.003, PII S0378517307007569
-
Nakase I., Lai H., Singh N. P., Sasaki T., Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugation International Journal of Pharmaceutics 2007 354 1-2 28 33 (Pubitemid 351400327)
-
(2008)
International Journal of Pharmaceutics
, vol.354
, Issue.1-2
, pp. 28-33
-
-
Nakase, I.1
Lai, H.2
Singh, N.P.3
Sasaki, T.4
-
39
-
-
27144556223
-
Targeted treatment of cancer with artemisinin and artemisinin-tagged iron-carrying compounds
-
DOI 10.1517/14728222.9.5.995
-
Lai H., Sasaki T., Singh N. P., Targeted treatment of cancer with artemisinin and artemisinin-tagged iron-carrying compounds Expert Opinion on Therapeutic Targets 2005 9 5 995 1007 (Pubitemid 41488836)
-
(2005)
Expert Opinion on Therapeutic Targets
, vol.9
, Issue.5
, pp. 995-1007
-
-
Lai, H.1
Sasaki, T.2
Singh, N.P.3
-
40
-
-
68249142819
-
Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction
-
Stockwin L. H., Han B., Yu S. X., Hollingshead M. G., Elsohly M. A., Gul W., Slade D., Galal A. M., Newton D. L., Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction International Journal of Cancer 2009 125 6 1266 1275
-
(2009)
International Journal of Cancer
, vol.125
, Issue.6
, pp. 1266-1275
-
-
Stockwin, L.H.1
Han, B.2
Yu, S.X.3
Hollingshead, M.G.4
Elsohly, M.A.5
Gul, W.6
Slade, D.7
Galal, A.M.8
Newton, D.L.9
-
41
-
-
34447325413
-
Dihydroartemisinin exerts cytotoxic effects and inhibits hypoxia inducible factor-1 activation in C6 glioma cells
-
Huang X. J., Ma Z. Q., Zhang W. P., Lu Y. B., Wei E. Q., Dihydroartemisinin exerts cytotoxic effects and inhibits hypoxia inducible factor-1 activation in C6 glioma cells Journal of Pharmacy and Pharmacology 2007 59 6 849 856
-
(2007)
Journal of Pharmacy and Pharmacology
, vol.59
, Issue.6
, pp. 849-856
-
-
Huang, X.J.1
Ma, Z.Q.2
Zhang, W.P.3
Lu, Y.B.4
Wei, E.Q.5
-
42
-
-
0036118607
-
The iron metabolism of neoplastic cells: Alterations that facilitate proliferation?
-
DOI 10.1016/S1040-8428(01)00213-X, PII S104084280100213X
-
Kwok J. C., Richardson D. R., The iron metabolism of neoplastic cells: alterations that facilitate proliferation? Critical Reviews in Oncology/Hematology 2002 42 1 65 78 (Pubitemid 34229148)
-
(2002)
Critical Reviews in Oncology/Hematology
, vol.42
, Issue.1
, pp. 65-78
-
-
Kwok, J.C.1
Richardson, D.R.2
-
43
-
-
4444383530
-
Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron
-
DOI 10.1016/j.freeradbiomed.2004.06.023, PII S0891584904004940
-
Efferth T., Benakis A., Romero M. R., Tomicic M., Rauh R., Steinbach D., Hfer R., Stamminger T., Oesch F., Kaina B., Marschall M., Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron Free Radical Biology and Medicine 2004 37 7 998 1009 (Pubitemid 39164582)
-
(2004)
Free Radical Biology and Medicine
, vol.37
, Issue.7
, pp. 998-1009
-
-
Efferth, T.1
Benakis, A.2
Romero, M.R.3
Tomicic, M.4
Rauh, R.5
Steinbach, D.6
Hafer, R.7
Stamminger, T.8
Oesch, F.9
Kaina, B.10
Marschall, M.11
-
44
-
-
79954480233
-
Artesunate inhibits growth and induces apoptosis in human osteosarcoma HOS cell line in vitro and in vivo
-
Xu Q., Li Z. -X., Peng H. -Q., Sun Z. -W., Cheng R. -L., Ye Z. -M., Li W. -X., Artesunate inhibits growth and induces apoptosis in human osteosarcoma HOS cell line In vitro and In vivo Biomedicine and Biotechnology 2011 12 4 247 255
-
(2011)
Biomedicine and Biotechnology
, vol.12
, Issue.4
, pp. 247-255
-
-
Xu, Q.1
Li, Z.-X.2
Peng, H.-Q.3
Sun, Z.-W.4
Cheng, R.-L.5
Ye, Z.-M.6
Li, W.-X.7
-
45
-
-
0022383509
-
Transferrin receptor: Its biological significance
-
DOI 10.1007/BF01871086
-
May W. S., Cuatrecasas P., Transferrin receptor: its biological significance Journal of Membrane Biology 1985 88 3 205 215 (Pubitemid 16173464)
-
(1985)
Journal of Membrane Biology
, vol.88
, Issue.3
, pp. 205-215
-
-
May Jr., W.S.1
Cuatrecasas, P.2
-
46
-
-
0034234580
-
Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer
-
DOI 10.1002/1097-0142(20000701)89:1<123::AID-CNCR17>3.0.CO;2-9
-
Bostwick D. G., Alexander E. E., Singh R., Shan A., Qian J., Santella R. M., Oberley L. W., Yan T., Zhong W., Jiang X., Oberley T. D., Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer Cancer 2000 89 1 123 134 (Pubitemid 30451282)
-
(2000)
Cancer
, vol.89
, Issue.1
, pp. 123-134
-
-
Bostwick, D.G.1
Alexander, E.E.2
Singh, R.3
Shan, A.4
Qian, J.5
Santella, R.M.6
Oberley, L.W.7
Yan, T.8
Zhong, W.9
Jiang, X.10
Oberley, T.D.11
-
47
-
-
4243845083
-
A radical approach to cancer
-
Das U. N., A radical approach to cancer Medical Science Monitor 2002 8 4 RA79 RA92
-
(2002)
Medical Science Monitor
, vol.8
, Issue.4
-
-
Das, U.N.1
-
48
-
-
54049085042
-
SPC3042: A proapoptotic survivin inhibitor
-
Hansen J. B., Fisker N., Westergaard M., Kjrulff L. S., Hansen H. F., Thrue C. A., Rosenbohm C., Wissenbach M., rum H., Koch T., SPC3042: a proapoptotic survivin inhibitor Molecular Cancer Therapeutics 2008 7 9 2736 2745
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, Issue.9
, pp. 2736-2745
-
-
Hansen, J.B.1
Fisker, N.2
Westergaard, M.3
Kjrulff, L.S.4
Hansen, H.F.5
Thrue, C.A.6
Rosenbohm, C.7
Wissenbach, M.8
Rum, H.9
Koch, T.10
-
49
-
-
37849019012
-
Artemisinin and a series of novel endoperoxide antimalarials exert early effects on digestive vacuole morphology
-
Crespo M. D. P., Avery T. D., Hanssen E., Fox E., Robinson T. V., Valente P., Taylor D. K., Tilley L., Artemisinin and a series of novel endoperoxide antimalarials exert early effects on digestive vacuole morphology Antimicrobial Agents and Chemotherapy 2008 52 1 98 109
-
(2008)
Antimicrobial Agents and Chemotherapy
, vol.52
, Issue.1
, pp. 98-109
-
-
Crespo, M.D.P.1
Avery, T.D.2
Hanssen, E.3
Fox, E.4
Robinson, T.V.5
Valente, P.6
Taylor, D.K.7
Tilley, L.8
-
50
-
-
33847115335
-
In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from São Tomé and Príncipe
-
DOI 10.1111/j.1365-3156.2006.01789.x
-
Ferreira I. D., Lopes D., Martinelli A., Ferreira C., Do Rosrio V. E., Cravo P., In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from So Tomé and Prncipe Tropical Medicine and International Health 2007 12 3 353 362 (Pubitemid 46280625)
-
(2007)
Tropical Medicine and International Health
, vol.12
, Issue.3
, pp. 353-362
-
-
Ferreira, I.D.1
Lopes, D.2
Martinelli, A.3
Ferreira, C.4
Do Rosario, V.E.5
Cravo, P.6
-
51
-
-
77649189381
-
Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo
-
Du J. H., Zhang H. D., Ma Z. J., Ji K. M., Artesunate induces oncosis-like cell death In vitro and has antitumor activity against pancreatic cancer xenografts In vivo Cancer Chemotherapy and Pharmacology 2010 65 5 895 902
-
(2010)
Cancer Chemotherapy and Pharmacology
, vol.65
, Issue.5
, pp. 895-902
-
-
Du, J.H.1
Zhang, H.D.2
Ma, Z.J.3
Ji, K.M.4
-
52
-
-
72049100401
-
Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines
-
Michaelis M., Kleinschmidt M. C., Barth S., Rothweiler F., Geiler J., Breitling R., Mayer B., Deubzer H., Witt O., Kreuter J., Doerr H. W., Cinatl J., Cinatl J., Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines Biochemical Pharmacology 2010 79 2 130 136
-
(2010)
Biochemical Pharmacology
, vol.79
, Issue.2
, pp. 130-136
-
-
Michaelis, M.1
Kleinschmidt, M.C.2
Barth, S.3
Rothweiler, F.4
Geiler, J.5
Breitling, R.6
Mayer, B.7
Deubzer, H.8
Witt, O.9
Kreuter, J.10
Doerr, H.W.11
Cinatl, J.12
Cinatl, J.13
-
53
-
-
33646984927
-
Dihydroartemisinin enhances radiosensitivity of human glioma cells in vitro
-
Kim S. J., Kim M. S., Lee J. W., Lee C. H., Yoo H., Shin S. H., Park M. J., Lee S. H., Dihydroartemisinin enhances radiosensitivity of human glioma cells In vitro Journal of Cancer Research and Clinical Oncology. 2006 132 2 129 135
-
(2006)
Journal of Cancer Research and Clinical Oncology.
, vol.132
, Issue.2
, pp. 129-135
-
-
Kim, S.J.1
Kim, M.S.2
Lee, J.W.3
Lee, C.H.4
Yoo, H.5
Shin, S.H.6
Park, M.J.7
Lee, S.H.8
-
54
-
-
79952197787
-
Single-cell analysis of dihydroartemisinin-induced apoptosis through reactive oxygen species-mediated caspase-8 activation and mitochondrial pathway in ASTC-a-1 cells using fluorescence imaging techniques
-
Lu Y. Y., Chen T. S., Wang X. P., Li L., Single-cell analysis of dihydroartemisinin-induced apoptosis through reactive oxygen species-mediated caspase-8 activation and mitochondrial pathway in ASTC-a-1 cells using fluorescence imaging techniques Journal of Biomedical Optics 2010 15 4 046028
-
(2010)
Journal of Biomedical Optics
, vol.15
, Issue.4
, pp. 046028
-
-
Lu, Y.Y.1
Chen, T.S.2
Wang, X.P.3
Li, L.4
-
55
-
-
74749095653
-
Dihydroartemisinin can inhibit calmodulin, calmodulin-dependent phosphodiesterase activity and stimulate cellular immune responses
-
Noori S., Hassan Z. M., Taghikhani M., Rezaei B., Habibi Z., Dihydroartemisinin can inhibit calmodulin, calmodulin-dependent phosphodiesterase activity and stimulate cellular immune responses International Immunopharmacology 2010 10 2 213 217
-
(2010)
International Immunopharmacology
, vol.10
, Issue.2
, pp. 213-217
-
-
Noori, S.1
Hassan, Z.M.2
Taghikhani, M.3
Rezaei, B.4
Habibi, Z.5
-
56
-
-
33947385343
-
Calcium and survivin are involved in the induction of apoptosis by dihydroartemisinin in human lung cancer SPC-A-1 cells
-
DOI 10.1358/mf.2007.29.1.1063493
-
Mu D., Chen W., Yu B., Zhang C., Zhang Y., Qi H., Calcium and survivin are involved in the induction of apoptosis by dihydroartemisinin in human lung cancer SPC-A-1 cells Methods and Findings in Experimental and Clinical Pharmacology 2007 29 1 33 38 (Pubitemid 46447221)
-
(2007)
Methods and Findings in Experimental and Clinical Pharmacology
, vol.29
, Issue.1
, pp. 33-38
-
-
Mu, D.1
Chen, W.2
Yu, B.3
Zhang, C.4
Zhang, Y.5
Qi, H.6
-
57
-
-
38049022026
-
The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells
-
Mu D., Zhang W., Chu D., Liu T., Xie Y., Fu E., Jin F., The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells Cancer Chemotherapy and Pharmacology 2008 61 4 639 645
-
(2008)
Cancer Chemotherapy and Pharmacology
, vol.61
, Issue.4
, pp. 639-645
-
-
Mu, D.1
Zhang, W.2
Chu, D.3
Liu, T.4
Xie, Y.5
Fu, E.6
Jin, F.7
-
58
-
-
34250344275
-
Willmar Schwabe Award 2006: Antiplasmodial and antitumor activity of artemisinin - From bench to bedside
-
DOI 10.1055/s-2007-967138
-
Efferth T., Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin from bench to bedside Planta Medica 2007 73 4 299 309 (Pubitemid 46910410)
-
(2007)
Planta Medica
, vol.73
, Issue.4
, pp. 299-309
-
-
Efferth, T.1
-
59
-
-
67650669265
-
Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1 and P-glycoprotein overexpression
-
Riganti C., Doublier S., Viarisio D., Miraglia E., Pescarmona G., Ghigo D., Bosia A., Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1 and P-glycoprotein overexpression British Journal of Pharmacology 2009 156 7 1054 1066
-
(2009)
British Journal of Pharmacology
, vol.156
, Issue.7
, pp. 1054-1066
-
-
Riganti, C.1
Doublier, S.2
Viarisio, D.3
Miraglia, E.4
Pescarmona, G.5
Ghigo, D.6
Bosia, A.7
-
60
-
-
77950201383
-
Subcellular localization of a fluorescent artemisinin derivative to endoplasmic reticulum
-
Liu Y., Lok C. N., Ko B. C. B., Shum T. Y. T., Wong M. K., Che C. M., Subcellular localization of a fluorescent artemisinin derivative to endoplasmic reticulum Organic Letters 2010 12 7 1420 1423
-
(2010)
Organic Letters
, vol.12
, Issue.7
, pp. 1420-1423
-
-
Liu, Y.1
Lok, C.N.2
Ko, B.C.B.3
Shum, T.Y.T.4
Wong, M.K.5
Che, C.M.6
-
61
-
-
77949356490
-
Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells
-
Morrissey C., Gallis B., Solazzi J. W., Kim B. J., Gulati R., Vakar-Lopez F., Goodlett D. R., Vessella R. L., Sasaki T., Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells Anti-Cancer Drugs 2010 21 4 423 432
-
(2010)
Anti-Cancer Drugs
, vol.21
, Issue.4
, pp. 423-432
-
-
Morrissey, C.1
Gallis, B.2
Solazzi, J.W.3
Kim, B.J.4
Gulati, R.5
Vakar-Lopez, F.6
Goodlett, D.R.7
Vessella, R.L.8
Sasaki, T.9
-
62
-
-
63449093129
-
Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells
-
Lu Y. Y., Chen T. S., Qu J. L., Pan W. L., Sun L., Wei X. B., Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells Journal of Biomedical Science 2009 16 1, article 16
-
(2009)
Journal of Biomedical Science
, vol.16
, Issue.ARTICLE 16
-
-
Lu, Y.Y.1
Chen, T.S.2
Qu, J.L.3
Pan, W.L.4
Sun, L.5
Wei, X.B.6
-
63
-
-
79953779279
-
In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents
-
Gravett A. M., Liu W. M., Krishna S., Chan W. C., Haynes R. K., Wilson N. L., Dalgleish A. G., In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents Cancer Chemotherapy and Pharmacology 2010 569 577
-
(2010)
Cancer Chemotherapy and Pharmacology
, pp. 569-577
-
-
Gravett, A.M.1
Liu, W.M.2
Krishna, S.3
Chan, W.C.4
Haynes, R.K.5
Wilson, N.L.6
Dalgleish, A.G.7
-
65
-
-
4043181214
-
Cancer genes and the pathways they control
-
DOI 10.1038/nm1087
-
Vogelstein B., Kinzler K. W., Cancer genes and the pathways they control Nature Medicine 2004 10 8 789 799 (Pubitemid 39070849)
-
(2004)
Nature Medicine
, vol.10
, Issue.8
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
66
-
-
0027267309
-
Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells
-
Woerdenbag H. J., Moskal T. A., Pras N., Malingré T. M., El-Feraly F. S., Kampinga H. H., Konings A. W. T., Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells Journal of Natural Products 1993 56 6 849 856 (Pubitemid 23195612)
-
(1993)
Journal of Natural Products (Lloydia)
, vol.56
, Issue.6
, pp. 849-856
-
-
Woerdenbag, H.J.1
Moskal, T.A.2
Pras, N.3
Malingre, T.M.4
El-Feraly, F.S.5
Kampinga, H.H.6
Konings, A.W.T.7
-
67
-
-
53049086416
-
Experimental therapy of hepatoma with artemisinin and Its derivatives: In vitro and in vivo activity, chemosensitization, and mechanisms of action
-
Hou J., Wang D., Zhang R., Wang H., Experimental therapy of hepatoma with artemisinin and Its derivatives: In vitro and In vivo activity, chemosensitization, and mechanisms of action Clinical Cancer Research 2008 14 17 5519 5530
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.17
, pp. 5519-5530
-
-
Hou, J.1
Wang, D.2
Zhang, R.3
Wang, H.4
-
68
-
-
52949104421
-
Analyzing anti-cancer action mechanisms of dihydroartemisinin using gene chip
-
Yao L., Xie H., Jin Q.-Y., Hu W.-L., Chen L.-J., Analyzing anti-cancer action mechanisms of dihydroartemisinin using gene chip China Journal of Chinese Materia Medica 2008 33 13 1583 1586
-
(2008)
China Journal of Chinese Materia Medica
, vol.33
, Issue.13
, pp. 1583-1586
-
-
Yao, L.1
Xie, H.2
Jin, Q.-Y.3
Hu, W.-L.4
Chen, L.-J.5
-
69
-
-
34347389476
-
Dihydroartemisinin is an inhibitor of ovarian cancer cell growth
-
DOI 10.1111/j.1745-7254.2007.00612.x
-
Jiao Y., Ge C. M., Meng Q. H., Cao J. P., Tong J., Fan S. J., Dihydroartemisinin is an inhibitor of ovarian cancer cell growth Acta Pharmacologica Sinica 2007 28 7 1045 1056 (Pubitemid 47020494)
-
(2007)
Acta Pharmacologica Sinica
, vol.28
, Issue.7
, pp. 1045-1056
-
-
Jiao, Y.1
Ge, C.-M.2
Meng, Q.-H.3
Cao, J.-P.4
Tong, J.5
Fan, S.-J.6
-
70
-
-
0035754080
-
To cycle or not to cycle: A critical decision in cancer
-
Malumbres M., Barbacid M., To cycle or not to cycle: a critical decision in cancer Nature Reviews Cancer 2001 1 3 222 231 (Pubitemid 33741897)
-
(2001)
Nature Reviews Cancer
, vol.1
, Issue.3
, pp. 222-231
-
-
Malumbres, M.1
Barbacid, M.2
-
73
-
-
79953707600
-
Anti-tumor effects of dihydroartemisinin on human osteosarcoma
-
Ji Y., Zhang Y. C., Pei L. B., Shi L. L., Yan J. L., Ma X. H., Anti-tumor effects of dihydroartemisinin on human osteosarcoma Molecular and Cellular Biochemistry 2011 351 1-2 99 108
-
(2011)
Molecular and Cellular Biochemistry
, vol.351
, Issue.12
, pp. 99-108
-
-
Ji, Y.1
Zhang, Y.C.2
Pei, L.B.3
Shi, L.L.4
Yan, J.L.5
Ma, X.H.6
-
74
-
-
59449109184
-
Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo
-
Chen H., Sun B., Pan S., Jiang H., Sun X., Dihydroartemisinin inhibits growth of pancreatic cancer cells In vitro and In vivo Anti-Cancer Drugs 2009 20 2 131 140
-
(2009)
Anti-Cancer Drugs
, vol.20
, Issue.2
, pp. 131-140
-
-
Chen, H.1
Sun, B.2
Pan, S.3
Jiang, H.4
Sun, X.5
-
75
-
-
79958165534
-
Anticancer effect of dihydroartemisinin (DHA) in a pancreatic tumor model evaluated by conventional methods and optical imaging
-
Aung W., Sogawa C., Furukawa T., Saga T., Anticancer effect of dihydroartemisinin (DHA) in a pancreatic tumor model evaluated by conventional methods and optical imaging Anticancer Research 2011 31 5 1549 1558
-
(2011)
Anticancer Research
, vol.31
, Issue.5
, pp. 1549-1558
-
-
Aung, W.1
Sogawa, C.2
Furukawa, T.3
Saga, T.4
-
76
-
-
84855521289
-
-
Cancer Chemotherapy and Pharmacology. In press
-
Wang S. -J., Sun B., Cheng Z. -X., Zhou H. -X., Gao Y., Kong R., Chen H., Jiang H. -C., Pan S. -H., Xue D. -B., Bai X. -W., Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF- B pathway. Cancer Chemotherapy and Pharmacology. In press
-
Dihydroartemisinin Inhibits Angiogenesis in Pancreatic Cancer by Targeting the NF- B Pathway
-
-
Wang, S.-J.1
Sun, B.2
Cheng, Z.-X.3
Zhou, H.-X.4
Gao, Y.5
Kong, R.6
Chen, H.7
Jiang, H.-C.8
Pan, S.-H.9
Xue, D.-B.10
Bai, X.-W.11
-
77
-
-
68149173166
-
Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy
-
Chen T., Li M., Zhang R., Wang H., Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy Journal of Cellular and Molecular Medicine 2009 13 7 1358 1370
-
(2009)
Journal of Cellular and Molecular Medicine
, vol.13
, Issue.7
, pp. 1358-1370
-
-
Chen, T.1
Li, M.2
Zhang, R.3
Wang, H.4
-
78
-
-
35048845221
-
Induction of apoptosis and inhibition of cell migration and tube-like formation by dihydroartemisinin in murine lymphatic endothelial cells
-
DOI 10.1159/000104418
-
Wang J., Guo Y., Zhang B. C., Chen Z. T., Gao J. F., Induction of apoptosis and inhibition of cell migration and tube-like formation by dihydroartemisinin in murine lymphatic endothelial cells Pharmacology 2007 80 4 207 218 (Pubitemid 47557254)
-
(2007)
Pharmacology
, vol.80
, Issue.4
, pp. 207-218
-
-
Wang, J.1
Guo, Y.2
Zhang, B.-C.3
Chen, Z.-T.4
Gao, J.-F.5
-
79
-
-
84866741435
-
The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis
-
In press
-
Cabello C. M., Lamore S. D., Bair III W. B., Qiao S., Azimian S., Lesson J. L., Wondrak G. T., The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis. Investigational New Drugs. In press
-
Investigational New Drugs
-
-
Cabello, C.M.1
Lamore, S.D.2
Bair Iii, W.B.3
Qiao, S.4
Azimian, S.5
Lesson, J.L.6
Wondrak, G.T.7
-
80
-
-
77956591096
-
Dihydroartemisinin induces apoptosis by a bak-dependent intrinsic pathway
-
Handrick R., Ontikatze T., Bauer K. D., Freier F., Rbel A., Drig J., Belka C., Jendrossek V., Dihydroartemisinin induces apoptosis by a bak-dependent intrinsic pathway Molecular Cancer Therapeutics 2010 9 9 2497 2510
-
(2010)
Molecular Cancer Therapeutics
, vol.9
, Issue.9
, pp. 2497-2510
-
-
Handrick, R.1
Ontikatze, T.2
Bauer, K.D.3
Freier, F.4
Rbel, A.5
Drig, J.6
Belka, C.7
Jendrossek, V.8
-
81
-
-
77951298166
-
Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKC /Raf/MAPKs and NF- B/AP-1-dependent mechanisms
-
Hwang Y. P., Yun H. J., Kim H. G., Han E. H., Lee G. W., Jeong H. G., Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKC /Raf/MAPKs and NF- B/AP-1-dependent mechanisms Biochemical Pharmacology 2010 79 12 1714 1726
-
(2010)
Biochemical Pharmacology
, vol.79
, Issue.12
, pp. 1714-1726
-
-
Hwang, Y.P.1
Yun, H.J.2
Kim, H.G.3
Han, E.H.4
Lee, G.W.5
Jeong, H.G.6
-
82
-
-
34447628307
-
Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells
-
DOI 10.1016/j.vph.2007.05.002, PII S1537189107000808
-
Zhou H. J., Wang W. Q., Wu G. D., Lee J., Li A., Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells Vascular Pharmacology 2007 47 2-3 131 138 (Pubitemid 47095451)
-
(2007)
Vascular Pharmacology
, vol.47
, Issue.2-3
, pp. 131-138
-
-
Zhou, H.-J.1
Wang, W.-Q.2
Wu, G.-D.3
Lee, J.4
Li, A.5
-
83
-
-
49749127985
-
Artemisinin inhibits tumor lymphangiogenesis by suppression of vascular endothelial growth factor C
-
Wang J., Zhang B., Guo Y., Li G., Xie Q., Zhu B., Gao J., Chen Z., Artemisinin inhibits tumor lymphangiogenesis by suppression of vascular endothelial growth factor C Pharmacology 2008 82 2 148 155
-
(2008)
Pharmacology
, vol.82
, Issue.2
, pp. 148-155
-
-
Wang, J.1
Zhang, B.2
Guo, Y.3
Li, G.4
Xie, Q.5
Zhu, B.6
Gao, J.7
Chen, Z.8
-
84
-
-
77951905390
-
Dihydroartemisinin improves the efficiency of chemotherapeutics in lung carcinomas in vivo and inhibits murine Lewis lung carcinoma cell line growth in vitro
-
Zhou H. J., Zhang J. L., Li A., Wang Z., Lou X. E., Dihydroartemisinin improves the efficiency of chemotherapeutics in lung carcinomas In vivo and inhibits murine Lewis lung carcinoma cell line growth In vitro Cancer Chemotherapy and Pharmacology 2010 66 1 21 29
-
(2010)
Cancer Chemotherapy and Pharmacology
, vol.66
, Issue.1
, pp. 21-29
-
-
Zhou, H.J.1
Zhang, J.L.2
Li, A.3
Wang, Z.4
Lou, X.E.5
-
85
-
-
28244475056
-
Dihydroartemisinin is cytotoxic to papillomavirus-expressing epithelial cells in vitro and in vivo
-
DOI 10.1158/0008-5472.CAN-05-1216
-
Disbrow G. L., Baege A. C., Kierpiec K. A., Yuan H., Centeno J. A., Thibodeaux C. A., Hartmann D., Schlegel R., Dihydroartemisinin is cytotoxic to papillomavirus-expressing epithelial cells In vitro and In vivo Cancer Research 2005 65 23 10854 10861 (Pubitemid 41713353)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 10854-10861
-
-
Disbrow, G.L.1
Baege, A.C.2
Kierpiec, K.A.3
Yuan, H.4
Centeno, J.A.5
Thibodeaux, C.A.6
Hartmann, D.7
Schlegel, R.8
-
86
-
-
77955028467
-
Effect of artesunate on human endometrial carcinoma
-
Lijuan W., Effect of artesunate on human endometrial carcinoma Journal of Medical Colleges of PLA 2010 25 3 143 151
-
(2010)
Journal of Medical Colleges of PLA
, vol.25
, Issue.3
, pp. 143-151
-
-
Lijuan, W.1
-
87
-
-
65749103049
-
Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells
-
Youns M., Efferth T., Reichling J., Fellenberg K., Bauer A., Hoheisel J. D., Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells Biochemical Pharmacology 2009 78 3 273 283
-
(2009)
Biochemical Pharmacology
, vol.78
, Issue.3
, pp. 273-283
-
-
Youns, M.1
Efferth, T.2
Reichling, J.3
Fellenberg, K.4
Bauer, A.5
Hoheisel, J.D.6
-
88
-
-
77955641219
-
First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases
-
Rasheed S. A. K., Efferth T., Asangani I. A., Allgayer H., First evidence that the antimalarial drug artesunate inhibits invasion and In vivo metastasis in lung cancer by targeting essential extracellular proteases International Journal of Cancer 2010 127 6 1475 1485
-
(2010)
International Journal of Cancer
, vol.127
, Issue.6
, pp. 1475-1485
-
-
Rasheed, S.A.K.1
Efferth, T.2
Asangani, I.A.3
Allgayer, H.4
-
89
-
-
44249089228
-
Differential sensitivity of colorectal cancer cell lines to artesunate is associated with expression of beta-catenin and E-cadherin
-
Li L. N., Zhang H. D., Yuan S. J., Yang D. X., Wang L., Sun Z. X., Differential sensitivity of colorectal cancer cell lines to artesunate is associated with expression of beta-catenin and E-cadherin European Journal of Pharmacology 2008 588 1 1 8
-
(2008)
European Journal of Pharmacology
, vol.588
, Issue.1
, pp. 1-8
-
-
Li, L.N.1
Zhang, H.D.2
Yuan, S.J.3
Yang, D.X.4
Wang, L.5
Sun, Z.X.6
-
90
-
-
73449131476
-
Effect of artesunate on inhibiting proliferation and inducing apoptosis of SP2/0 myeloma cells through affecting NF B p65
-
Li S., Xue F., Cheng Z., Yang X., Wang S., Geng F., Pan L., Effect of artesunate on inhibiting proliferation and inducing apoptosis of SP2/0 myeloma cells through affecting NF B p65 International Journal of Hematology 2009 90 4 513 521
-
(2009)
International Journal of Hematology
, vol.90
, Issue.4
, pp. 513-521
-
-
Li, S.1
Xue, F.2
Cheng, Z.3
Yang, X.4
Wang, S.5
Geng, F.6
Pan, L.7
-
91
-
-
78651267641
-
Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells
-
Weifeng T., Feng S., Xiangji L., Changqing S., Zhiquan Q., Huazhong Z., Peining Y., Yong Y., Mengchao W., Xiaoqing J., Wan-yee L., Artemisinin inhibits In vitro and In vivo invasion and metastasis of human hepatocellular carcinoma cells Phytomedicine 2011 18 2-3 158 162
-
(2011)
Phytomedicine
, vol.18
, Issue.23
, pp. 158-162
-
-
Weifeng, T.1
Feng, S.2
Xiangji, L.3
Changqing, S.4
Zhiquan, Q.5
Huazhong, Z.6
Peining, Y.7
Yong, Y.8
Mengchao, W.9
Xiaoqing, J.10
Wan-Yee, L.11
-
92
-
-
80051506043
-
Down-regulation of BMI-1 cooperates with artemisinin on growth inhibition of nasopharyngeal carcinoma cells
-
Wu J., Hu D., Yang G., Zhou J., Yang C., Gao Y., Zhu Z., Down-regulation of BMI-1 cooperates with artemisinin on growth inhibition of nasopharyngeal carcinoma cells Journal of Cellular Biochemistry 2011 112 7 1938 1948
-
(2011)
Journal of Cellular Biochemistry
, vol.112
, Issue.7
, pp. 1938-1948
-
-
Wu, J.1
Hu, D.2
Yang, G.3
Zhou, J.4
Yang, C.5
Gao, Y.6
Zhu, Z.7
-
93
-
-
70349260586
-
Artemisinin reduces human melanoma cell migration by down-regulating v 3 integrin and reducing metalloproteinase 2 production
-
Buommino E., Baroni A., Canozo N., Petrazzuolo M., Nicoletti R., Vozza A., Tufano M. A., Artemisinin reduces human melanoma cell migration by down-regulating v 3 integrin and reducing metalloproteinase 2 production Investigational New Drugs 2008 27 5 412 418
-
(2008)
Investigational New Drugs
, vol.27
, Issue.5
, pp. 412-418
-
-
Buommino, E.1
Baroni, A.2
Canozo, N.3
Petrazzuolo, M.4
Nicoletti, R.5
Vozza, A.6
Tufano, M.A.7
-
94
-
-
77952420656
-
Dihydroartemisinin inactivates NF- B and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo
-
Wang S. J., Gao Y., Chen H., Kong R., Jiang H. C., Pan S. H., Xue D. B., Bai X. W., Sun B., Dihydroartemisinin inactivates NF- B and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both In vitro and In vivo Cancer Letters 2010 293 1 99 108
-
(2010)
Cancer Letters
, vol.293
, Issue.1
, pp. 99-108
-
-
Wang, S.J.1
Gao, Y.2
Chen, H.3
Kong, R.4
Jiang, H.C.5
Pan, S.H.6
Xue, D.B.7
Bai, X.W.8
Sun, B.9
-
95
-
-
0034597594
-
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
-
Uren A. G., Wong L., Pakusch M., Fowler K. J., Burrows F. J., Vaux D. L., Choo K. H. A., Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype Current Biology 2000 10 21 1319 1328
-
(2000)
Current Biology
, vol.10
, Issue.21
, pp. 1319-1328
-
-
Uren, A.G.1
Wong, L.2
Pakusch, M.3
Fowler, K.J.4
Burrows, F.J.5
Vaux, D.L.6
Choo, K.H.A.7
-
96
-
-
59049096024
-
Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression
-
Willoughby J. A., Sundar S. N., Cheung M., Tin A. S., Modiano J., Firestone G. L., Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression Journal of Biological Chemistry 2009 284 4 2203 2213
-
(2009)
Journal of Biological Chemistry
, vol.284
, Issue.4
, pp. 2203-2213
-
-
Willoughby, J.A.1
Sundar, S.N.2
Cheung, M.3
Tin, A.S.4
Modiano, J.5
Firestone, G.L.6
-
97
-
-
77953496226
-
Chemosensitization of prostate cancer by modulating Bcl-2 family proteins
-
Karnak D., Xu L., Chemosensitization of prostate cancer by modulating Bcl-2 family proteins Current Drug Targets 2010 11 6 699 707
-
(2010)
Current Drug Targets
, vol.11
, Issue.6
, pp. 699-707
-
-
Karnak, D.1
Xu, L.2
-
98
-
-
34250308322
-
Apoptosis: A Review of Programmed Cell Death
-
DOI 10.1080/01926230701320337, PII 779478428
-
Elmore S., Apoptosis: a review of programmed cell death Toxicologic Pathology 2007 35 4 495 516 (Pubitemid 46911891)
-
(2007)
Toxicologic Pathology
, vol.35
, Issue.4
, pp. 495-516
-
-
Elmore, S.1
-
99
-
-
40149097301
-
Artesunate induces ROS-mediated apoptosis in Doxorubicin-resistant T leukemia cells
-
Efferth T., Glaisi M., Merling A., Krammer P. H., Li-Weber M., Artesunate induces ROS-mediated apoptosis in Doxorubicin-resistant T leukemia cells PLoS ONE 2007 2 8, article e693
-
(2007)
PLoS ONE
, vol.2
, Issue.ARTICLE E693
-
-
Efferth, T.1
Glaisi, M.2
Merling, A.3
Krammer, P.H.4
Li-Weber, M.5
-
100
-
-
77953714651
-
Dihydroartemisinin upregulates death receptor 5 expression and cooperates with TRAIL to induce apoptosis in human prostate cancer cells
-
He Q., Shi J., Shen X. L., An J., Sun H., Wang L., Hu Y. J., Sun Q., Fu L. C., Sheikh M. S., Huang Y., Dihydroartemisinin upregulates death receptor 5 expression and cooperates with TRAIL to induce apoptosis in human prostate cancer cells Cancer Biology and Therapy 2010 9 10 817 823
-
(2010)
Cancer Biology and Therapy
, vol.9
, Issue.10
, pp. 817-823
-
-
He, Q.1
Shi, J.2
Shen, X.L.3
An, J.4
Sun, H.5
Wang, L.6
Hu, Y.J.7
Sun, Q.8
Fu, L.C.9
Sheikh, M.S.10
Huang, Y.11
-
101
-
-
33746851956
-
Tumor metastasis: Mechanistic insights and clinical challenges
-
DOI 10.1038/nm1469, PII NM1469
-
Steeg P. S., Tumor metastasis: mechanistic insights and clinical challenges Nature Medicine 2006 12 8 895 904 (Pubitemid 44175140)
-
(2006)
Nature Medicine
, vol.12
, Issue.8
, pp. 895-904
-
-
Steeg, P.S.1
-
102
-
-
38949143636
-
Cancer invasion and metastasis: Changing views
-
DOI 10.1002/path.2282
-
Duffy M. J., McGowan P. M., Gallagher W. M., Cancer invasion and metastasis: changing views Journal of Pathology 2008 214 3 283 293 (Pubitemid 351212383)
-
(2008)
Journal of Pathology
, vol.214
, Issue.3
, pp. 283-293
-
-
Duffy, M.J.1
McGowan, P.M.2
Gallagher, W.M.3
-
103
-
-
59849109215
-
Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells
-
Hung W. C., Chang H. C., Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells Journal of Agricultural and Food Chemistry 2009 57 1 76 82
-
(2009)
Journal of Agricultural and Food Chemistry
, vol.57
, Issue.1
, pp. 76-82
-
-
Hung, W.C.1
Chang, H.C.2
-
104
-
-
0036841843
-
Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1α/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol
-
DOI 10.1124/mol.62.5.975
-
Hur E., Kim H. H., Choi S. M., Kim J. H., Yim S., Kwon H. J., Choi Y., Kim D. K., Lee M. O., Park H., Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1 /aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol Molecular Pharmacology 2002 62 5 975 982 (Pubitemid 35222488)
-
(2002)
Molecular Pharmacology
, vol.62
, Issue.5
, pp. 975-982
-
-
Hur, E.1
Kim, H.-H.2
Choi, S.M.3
Kim, J.H.4
Yim, S.5
Kwon, H.J.6
Choi, Y.7
Kim, D.K.8
Lee, M.-O.9
Park, H.10
-
105
-
-
33746531759
-
Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins
-
DOI 10.1038/sj.tpj.6500371, PII 6500371
-
Anfosso L., Efferth T., Albini A., Pfeffer U., Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins Pharmacogenomics Journal 2006 6 4 269 278 (Pubitemid 44137954)
-
(2006)
Pharmacogenomics Journal
, vol.6
, Issue.4
, pp. 269-278
-
-
Anfosso, L.1
Efferth, T.2
Albini, A.3
Pfeffer, U.4
-
106
-
-
2142650659
-
Antimalarial dihydroartemisinin also inhibits angiogenesis
-
Chen H. H., Zhou H. J., Wang W. Q., Wu G. D., Antimalarial dihydroartemisinin also inhibits angiogenesis Cancer Chemotherapy and Pharmacology 2004 53 5 423 432
-
(2004)
Cancer Chemotherapy and Pharmacology
, vol.53
, Issue.5
, pp. 423-432
-
-
Chen, H.H.1
Zhou, H.J.2
Wang, W.Q.3
Wu, G.D.4
-
107
-
-
46449092974
-
Dihydroartemisinin potentiates the cytotoxic effect of temozolomide in rat C6 glioma cells
-
Huang X. J., Li C. T., Zhang W. P., Lu Y. B., Fang S. H., Wei E. Q., Dihydroartemisinin potentiates the cytotoxic effect of temozolomide in rat C6 glioma cells Pharmacology 2008 82 1 1 9
-
(2008)
Pharmacology
, vol.82
, Issue.1
, pp. 1-9
-
-
Huang, X.J.1
Li, C.T.2
Zhang, W.P.3
Lu, Y.B.4
Fang, S.H.5
Wei, E.Q.6
-
108
-
-
34249324102
-
The pharmacology of cancer resistance
-
O'Connor R., The pharmacology of cancer resistance Anticancer Research 2007 27 3 A 1267 1272 (Pubitemid 46813088)
-
(2007)
Anticancer Research
, vol.27
, Issue.A
, pp. 1267-1272
-
-
O'Connor, R.1
-
109
-
-
79958748186
-
Cytotoxic activity of artemisinin derivatives against cholangiocarcinoma (CL-6) and hepatocarcinoma (Hep-G2) cell lines
-
Chaijaroenkul W., Viyanant V., Mahavorasirikul W., Na-Bangchang K., Cytotoxic activity of artemisinin derivatives against cholangiocarcinoma (CL-6) and hepatocarcinoma (Hep-G2) cell lines Asian Pacific Journal of Cancer Prevention 2011 12 1 55 59
-
(2011)
Asian Pacific Journal of Cancer Prevention
, vol.12
, Issue.1
, pp. 55-59
-
-
Chaijaroenkul, W.1
Viyanant, V.2
Mahavorasirikul, W.3
Na-Bangchang, K.4
-
110
-
-
27944491872
-
Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells
-
Singh N. P., Lai H. C., Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells Anticancer Research 2005 25 6 B 4325 4331 (Pubitemid 41665224)
-
(2005)
Anticancer Research
, vol.25
, Issue.B
, pp. 4325-4331
-
-
Singh, N.P.1
Lai, H.C.2
-
111
-
-
79551492819
-
The antimalarial agent artesunate possesses anticancer properties that can be enhanced by combination strategies
-
Liu W. M., Gravett A. M., Dalgleish A. G., The antimalarial agent artesunate possesses anticancer properties that can be enhanced by combination strategies International Journal of Cancer 2011 128 6 1471 1480
-
(2011)
International Journal of Cancer
, vol.128
, Issue.6
, pp. 1471-1480
-
-
Liu, W.M.1
Gravett, A.M.2
Dalgleish, A.G.3
-
112
-
-
78650236183
-
Effect of hyperbaric oxygen on the anticancer effect of artemisinin on molt-4 human leukemia cells
-
Ohgami Y., Elstad C. A., Chung E., Shirachi D. Y., Quock R. M., Lai H. C., Effect of hyperbaric oxygen on the anticancer effect of artemisinin on molt-4 human leukemia cells Anticancer Research 2010 30 11 4467 4470
-
(2010)
Anticancer Research
, vol.30
, Issue.11
, pp. 4467-4470
-
-
Ohgami, Y.1
Elstad, C.A.2
Chung, E.3
Shirachi, D.Y.4
Quock, R.M.5
Lai, H.C.6
-
113
-
-
77951220629
-
Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism
-
Witkowski B., Lelivre J., Barragn M. J.L., Laurent V., Su X. -Z., Berry A., Benoit-Vical F., Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism Antimicrobial Agents and Chemotherapy 2010 54 5 1872 1877
-
(2010)
Antimicrobial Agents and Chemotherapy
, vol.54
, Issue.5
, pp. 1872-1877
-
-
Witkowski, B.1
Lelivre, J.2
Barragn, M.J.L.3
Laurent, V.4
Su, X.-Z.5
Berry, A.6
Benoit-Vical, F.7
-
114
-
-
0030760957
-
Antineoplastic drugs that interfere with iron metabolism in cancer cells
-
DOI 10.1016/S0065-2571(96)00010-6, PII S0065257196000106
-
Head J. F., Wang F., Elliott R. L., Antineoplastic drugs that interfere with iron metabolism in cancer cells Advances in Enzyme Regulation 1997 37 147 169 (Pubitemid 27371560)
-
(1997)
Advances in Enzyme Regulation
, vol.37
, pp. 147-169
-
-
Head, J.F.1
Wang, F.2
Elliott, R.L.3
-
115
-
-
77950958513
-
Factors determining sensitivity or resistance of tumor cell lines towards artesunate
-
Sertel S., Eichhorn T., Sieber S., Sauer A., Weiss J., Plinkert P. K., Efferth T., Factors determining sensitivity or resistance of tumor cell lines towards artesunate Chemico-Biological Interactions 2010 185 1 42 52
-
(2010)
Chemico-Biological Interactions
, vol.185
, Issue.1
, pp. 42-52
-
-
Sertel, S.1
Eichhorn, T.2
Sieber, S.3
Sauer, A.4
Weiss, J.5
Plinkert, P.K.6
Efferth, T.7
-
116
-
-
79957572444
-
Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells
-
Bachmeier B., Fichtner I., Killian P. H., Kronski E., Pfeffer U., Efferth T., Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells PLoS ONE 2011 6 5, article e20550
-
(2011)
PLoS ONE
, vol.6
, Issue.ARTICLE E20550
-
-
Bachmeier, B.1
Fichtner, I.2
Killian, P.H.3
Kronski, E.4
Pfeffer, U.5
Efferth, T.6
-
117
-
-
0032242275
-
In vitro neurotoxicity of artemisinin derivatives
-
McLean W., Ward S. A., In vitro neurotoxicity of artemisinin derivatives Médecine Tropicale 1998 58 3 28 31
-
(1998)
Médecine Tropicale
, vol.58
, Issue.3
, pp. 28-31
-
-
McLean, W.1
Ward, S.A.2
-
118
-
-
0036170794
-
Neurotoxic mode of action of artemisinin
-
DOI 10.1128/AAC.46.3.821-827.2002
-
Schmuck G., Roehrdanz E., Haynes R. K., Kahl R., Neurotoxic mode of action of artemisinin Antimicrobial Agents and Chemotherapy 2002 46 3 821 827 (Pubitemid 34157669)
-
(2002)
Antimicrobial Agents and Chemotherapy
, vol.46
, Issue.3
, pp. 821-827
-
-
Schmuck, G.1
Roehrdanz, E.2
Haynes, R.K.3
Kahl, R.4
-
119
-
-
0034445966
-
Clinical and neurophysiological study of the effects of multiple doses of artemisinin on brain-stem function in vietnamese patients
-
Kissinger E., Hien T. T., Hung N. T., Nam N. D., Tuyen N. L., Dinh B. V., Mann C., Phu N. H., Loc P. P., Simpson J. A., White N. J., Farrar J. J., Clinical and neurophysiological study of the effects of multiple doses of artemisinin on brain-stem function in vietnamese patients American Journal of Tropical Medicine and Hygiene 2000 63 1-2 48 55 (Pubitemid 32423094)
-
(2000)
American Journal of Tropical Medicine and Hygiene
, vol.63
, Issue.1-2
, pp. 48-55
-
-
Kissinger, E.1
Hien, T.T.2
Hung, N.T.3
Nam, N.D.4
Tuyen, N.L.5
Dinh, B.V.6
Mann, C.7
Phu, N.H.8
Loc, P.P.9
Simpson, J.A.10
White, N.J.11
Farrar, J.J.12
-
120
-
-
35648938743
-
Neurotoxicity and toxicokinetics of artelinic acid following repeated oral administration in rats
-
DOI 10.1080/10915810701582913, PII 783449679
-
Si Y., Li Q., Xie L., Bennett K., Weina P. J., Mog S., Johnson T. O., Neurotoxicity and toxicokinetics of artelinic acid following repeated oral administration in rats International Journal of Toxicology 2007 26 5 401 410 (Pubitemid 350034889)
-
(2007)
International Journal of Toxicology
, vol.26
, Issue.5
, pp. 401-410
-
-
Si, Y.1
Li, Q.2
Xie, L.3
Bennett, K.4
Weina, P.J.5
Mog, S.6
Johnson, T.O.7
-
121
-
-
77951436519
-
Toxicity of the antimalarial artemisinin and its dervatives
-
Efferth T., Kaina B., Toxicity of the antimalarial artemisinin and its dervatives Critical Reviews in Toxicology 2010 40 5 405 421
-
(2010)
Critical Reviews in Toxicology
, vol.40
, Issue.5
, pp. 405-421
-
-
Efferth, T.1
Kaina, B.2
-
122
-
-
0036975321
-
Case report of a laryngeal squamous cell carcinoma treated with artesunate
-
DOI 10.2298/AOO0204279S
-
Singh N. P., Verma K. B., Case report of a laryngeal squamous cell carcinoma treated with artesunate Archive of Oncology 2002 10 4 279 280 (Pubitemid 36164142)
-
(2002)
Archive of Oncology
, vol.10
, Issue.4
, pp. 279-280
-
-
Singh, N.P.1
Verma, K.B.2
-
123
-
-
33750858216
-
Case report of a pituitary macroadenoma treated with artemether
-
DOI 10.1177/1534735406295311
-
Singh N. P., Panwar V. K., Case report of a pituitary macroadenoma treated with artemether Integrative Cancer Therapies 2006 5 4 391 394 (Pubitemid 44722000)
-
(2006)
Integrative Cancer Therapies
, vol.5
, Issue.4
, pp. 391-394
-
-
Singh, N.P.1
Panwar, V.K.2
-
124
-
-
27644527323
-
Toxic brainstem encephalopathy after artemisinin treatment for breast cancer
-
DOI 10.1002/ana.20620
-
Panossian L. A., Garga N. I., Pelletier D., Toxic brainstem encephalopathy after artemisinin treatment for breast cancer Annals of Neurology 2005 58 5 812 813 (Pubitemid 41552563)
-
(2005)
Annals of Neurology
, vol.58
, Issue.5
, pp. 812-813
-
-
Panossian, L.A.1
Garga, N.I.2
Pelletier, D.3
-
126
-
-
39149087695
-
Artesunate combined with vinorelbine plus cisplatin in treatment of advanced non-small cell lung cancer: A randomized controlled trial
-
Zhang Z. Y., Yu S. Q., Miao L. Y., Huang X. Y., Zhang X. P., Zhu Y. P., Xia X. H., Li D. Q., Artesunate combined with vinorelbine plus cisplatin in treatment of advanced non-small cell lung cancer: a randomized controlled trial Journal of Chinese Integrative Medicine 2008 6 2 134 138
-
(2008)
Journal of Chinese Integrative Medicine
, vol.6
, Issue.2
, pp. 134-138
-
-
Zhang, Z.Y.1
Yu, S.Q.2
Miao, L.Y.3
Huang, X.Y.4
Zhang, X.P.5
Zhu, Y.P.6
Xia, X.H.7
Li, D.Q.8
-
127
-
-
79951892623
-
Synthesis of 10B-Substituited triazolyl artemisinins and their growth inhibitory activity against various cancer cells
-
Lee S., Synthesis of 10B-Substituited triazolyl artemisinins and their growth inhibitory activity against various cancer cells Bulletin of the Korean Chemical Society 2011 32 2 737 740
-
(2011)
Bulletin of the Korean Chemical Society
, vol.32
, Issue.2
, pp. 737-740
-
-
Lee, S.1
-
128
-
-
79955552010
-
Antiplasmodial and antitumor activity of dDHA analogs derived via the aza-Michael addition reaction
-
Feng F. S., Guantai E. M., Nell M. J., van Rensburg C. E. J., Hoppe H., Chibale K., Antiplasmodial and antitumor activity of dDHA analogs derived via the aza-Michael addition reaction Bioorganic and Medicinal Chemistry Letters 2000 21 10 2882 2886
-
(2000)
Bioorganic and Medicinal Chemistry Letters
, vol.21
, Issue.10
, pp. 2882-2886
-
-
Feng, F.S.1
Guantai, E.M.2
Nell, M.J.3
Van Rensburg, C.E.J.4
Hoppe, H.5
Chibale, K.6
-
129
-
-
0034596215
-
NMR studies on novel antitumor drug candidates, deoxoartemisinin and carboxypropyldeoxoartemisinin
-
DOI 10.1006/bbrc.2000.3086
-
Lee C. H., Hong H., Shin J., Jung M., Shin I., Yoon J., Lee W., NMR studies on novel antitumor drug candidates, deoxoartemisinin and carboxypropyldeoxoartemisinin Biochemical and Biophysical Research Communications 2000 274 2 359 369 (Pubitemid 30614324)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.274
, Issue.2
, pp. 359-369
-
-
Lee, C.-H.1
Hong, H.2
Shin, J.3
Jung, M.4
Shin, I.5
Yoon, J.6
Lee, W.7
-
130
-
-
33845919843
-
Biological mechanisms of action of novel C-10 non-acetal trioxane dimers in prostate cancer cell lines
-
DOI 10.1021/jm060803i
-
Alagbala A. A., McRiner A. J., Borstnik K., Labonte T., Chang W., D'Angelo J. G., Posner G. H., Foster B. A., Biological mechanisms of action of novel C-10 non-acetal trioxane dimers in prostate cancer cell lines Journal of Medicinal Chemistry 2006 49 26 7836 7842 (Pubitemid 46033673)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.26
, pp. 7836-7842
-
-
Alagbala, A.A.1
McRiner, A.J.2
Borstnik, K.3
Labonte, T.4
Chang, W.5
D'Angelo, J.G.6
Posner, G.H.7
Foster, B.A.8
-
131
-
-
77954320743
-
Cytotoxicity of artesunic acid homo- and heterodimer molecules toward sensitive and multidrug-resistant CCRF-CEM leukemia cells
-
Horwedel C., Tsogoeva S. B., Wei S., Efferth T., Cytotoxicity of artesunic acid homo- and heterodimer molecules toward sensitive and multidrug-resistant CCRF-CEM leukemia cells Journal of Medicinal Chemistry 2010 53 13 4842 4848
-
(2010)
Journal of Medicinal Chemistry
, vol.53
, Issue.13
, pp. 4842-4848
-
-
Horwedel, C.1
Tsogoeva, S.B.2
Wei, S.3
Efferth, T.4
-
132
-
-
10744231930
-
Antimalarial and Antitumor Evaluation of Novel C-10 Non-Acetal Dimers of 10β-(2-Hydroxyethyl)deoxoartemisinin
-
DOI 10.1021/jm030974c
-
Jeyadevan J. P., Bray P. G., Chadwick J., Mercer A. E., Byrne A., Ward S. A., Park B. K., Williams D. P., Cosstick R., Davies J., Higson A. P., Irving E., Posner G. H., O'Neill P. M., Antimalarial and Antitumor Evaluation of Novel C-10 Non-Acetal Dimers of 10 -(2-Hydroxyethyl)deoxoartemisinin Journal of Medicinal Chemistry 2004 47 5 1290 1298 (Pubitemid 38229131)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.5
, pp. 1290-1298
-
-
Jeyadevan, J.P.1
Bray, P.G.2
Chadwick, J.3
Mercer, A.E.4
Byrne, A.5
Ward, S.A.6
Park, B.K.7
Williams, D.P.8
Cosstick, R.9
Davies, J.10
Higson, A.P.11
Irving, E.12
Posner, G.H.13
O'Neill, P.M.14
-
133
-
-
0037435055
-
Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer
-
DOI 10.1021/jm020119d
-
Jung M., Lee S., Ham J., Lee K., Kim H., Kie Kim S., Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer Journal of Medicinal Chemistry 2003 46 6 987 994 (Pubitemid 36423145)
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, Issue.6
, pp. 987-994
-
-
Jung, M.1
Lee, S.2
Ham, J.3
Lee, K.4
Kim, H.5
Kie Kim, S.6
-
134
-
-
0034710713
-
Cholic acid derivatives as 1,2,4,5-tetraoxane carriers: Structure and antimalarial and antiproliferative activity
-
Opsenica D., Pocsfalvi G., Juranic Z., Tinant B., Declercq J. P., Kyle D. E., Milhous W. K., Solaja B. A., Cholic acid derivatives as 1,2,4,5-tetraoxane carriers: structure and antimalarial and antiproliferative activity Journal of Medicinal Chemistry 2000 43 17 3274 3282
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, Issue.17
, pp. 3274-3282
-
-
Opsenica, D.1
Pocsfalvi, G.2
Juranic, Z.3
Tinant, B.4
Declercq, J.P.5
Kyle, D.E.6
Milhous, W.K.7
Solaja, B.A.8
-
135
-
-
79953896669
-
Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties
-
Soomro S., Langenberg T., Mahringer A., Konkimalla V. B., Horwedel C., Holenya P., Brand A., Cetin C., Fricker G., Dewerchin M., Carmeliet P., Conway E. M., Jansen H., Efferth T., Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties Journal of Cellular and Molecular Medicine 2011 15 5 1122 1135
-
(2011)
Journal of Cellular and Molecular Medicine
, vol.15
, Issue.5
, pp. 1122-1135
-
-
Soomro, S.1
Langenberg, T.2
Mahringer, A.3
Konkimalla, V.B.4
Horwedel, C.5
Holenya, P.6
Brand, A.7
Cetin, C.8
Fricker, G.9
Dewerchin, M.10
Carmeliet, P.11
Conway, E.M.12
Jansen, H.13
Efferth, T.14
-
136
-
-
0029843392
-
Clinical pharmacology and therapeutic potential of artemisinin and its derivatives in the treatment of malaria
-
de Vries P. J., Dien T. K., Clinical pharmacology and therapeutic potential of artemisinin and its derivatives in the treatment of malaria Drugs 1996 52 6 818 836 (Pubitemid 26413293)
-
(1996)
Drugs
, vol.52
, Issue.6
, pp. 818-836
-
-
De Vries, P.J.1
Dien, T.K.2
-
137
-
-
7944222115
-
Artemisinins: Mechanisms of action and potential for resistance
-
DOI 10.1016/j.drup.2004.07.001, PII S1368764604000494
-
Krishna S., Uhlemann A. C., Haynes R. K., Artemisinins: mechanisms of action and potential for resistance Drug Resistance Updates 2004 7 4-5 233 244 (Pubitemid 39469096)
-
(2004)
Drug Resistance Updates
, vol.7
, Issue.4-5
, pp. 233-244
-
-
Krishna, S.1
Uhlemann, A.-C.2
Haynes, R.K.3
-
138
-
-
79952732772
-
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria
-
Charman S. A., Arbe-Barnes S., Bathurst I. C., Brund R., Campbell M., Charman W. N., Chiu F. C.K., Chollet J., Craft J. C., Creek D. J., Don Y., Matile H., Maurer M., Morizzi J., Nguyen T., Papastogiannidis P., Scheurer C., Shackleford D. M., Sriraghavan K., Stingelin L., Tang Y., Urwyler H., Wang X., White K. L., Wittlin S., Zhou L., Vennerstrom J. L., Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria Proceedings of the National Academy of Sciences of the United States of America 2011 108 11 4400 4405
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.11
, pp. 4400-4405
-
-
Charman, S.A.1
Arbe-Barnes, S.2
Bathurst, I.C.3
Brund, R.4
Campbell, M.5
Charman, W.N.6
Chiu, F.C.K.7
Chollet, J.8
Craft, J.C.9
Creek, D.J.10
Don, Y.11
Matile, H.12
Maurer, M.13
Morizzi, J.14
Nguyen, T.15
Papastogiannidis, P.16
Scheurer, C.17
Shackleford, D.M.18
Sriraghavan, K.19
Stingelin, L.20
Tang, Y.21
Urwyler, H.22
Wang, X.23
White, K.L.24
Wittlin, S.25
Zhou, L.26
Vennerstrom, J.L.27
more..
-
139
-
-
34247102609
-
In vitro and in vivo activities of synthetic trioxolanes against major human schistosome species
-
DOI 10.1128/AAC.01537-06
-
Xiao S. -H., Keiser J., Chollet J., Utzinger J., Dong Y., Endriss Y., Vennerstrom J. L., Tanner M., In vitro and In vivo activities of synthetic trioxolanes against major human schistosome species Antimicrobial Agents and Chemotherapy 2007 51 4 1440 1445 (Pubitemid 46586827)
-
(2007)
Antimicrobial Agents and Chemotherapy
, vol.51
, Issue.4
, pp. 1440-1445
-
-
Xiao, S.-H.1
Keiser, J.2
Chollet, J.3
Utzinger, J.4
Dong, Y.5
Endriss, Y.6
Vennerstrom, J.L.7
Tanner, M.8
-
140
-
-
41849117634
-
Chemical stability of the peroxide bond enables diversified synthesis of potent tetraoxane antimalarials
-
DOI 10.1021/jm701417a
-
Opsenica I., Opsenica D., Smith K. S., Milhous W. K., olaja B. A., Chemical stability of the peroxide bond enables diversified synthesis of potent tetraoxane antimalarials Journal of Medicinal Chemistry 2008 51 7 2261 2266 (Pubitemid 351503281)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.7
, pp. 2261-2266
-
-
Opsenica, I.1
Opsenica, D.2
Smith, K.S.3
Milhous, W.K.4
Solaja, B.A.5
-
141
-
-
35348910826
-
Deoxycholic acid-derived tetraoxane antimalarials and antiproliferatives
-
DOI 10.1021/jm070684m
-
Terzi N., Opsenica D., Mili D., Tinant B., Smith K. S., Milhous W. K., olaja B. A., Deoxycholic acid-derived tetraoxane antimalarials and antiproliferatives Journal of Medicinal Chemistry 2007 50 21 5118 5127 (Pubitemid 47585709)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.21
, pp. 5118-5127
-
-
Terzic, N.1
Opsenica, D.2
Milic, D.3
Tinant, B.4
Smith, K.S.5
Milhous, W.K.6
Solaja, B.A.7
-
143
-
-
0034329284
-
Reproductive functions in female patients treated with adjuvant and neoadjuvant chemotherapy for localized osteosarcoma of the extremity
-
Yuen A. R., Zou G., Turrisi A. T., Sause W., Komaki R., Wagner H., Aisner S. C., Livingston R. B., Blum R., Johnson D. H., Reproductive functions in female patients treated with adjuvant and neoadjuvant chemotherapy for localized osteosarcoma of the extremity Cancer 2000 89 9 1961 1965
-
(2000)
Cancer
, vol.89
, Issue.9
, pp. 1961-1965
-
-
Yuen, A.R.1
Zou, G.2
Turrisi, A.T.3
Sause, W.4
Komaki, R.5
Wagner, H.6
Aisner, S.C.7
Livingston, R.B.8
Blum, R.9
Johnson, D.H.10
-
144
-
-
61849111253
-
Inhibitive effect of artemether on tumor growth and angiogenesis in the rat C6 orthotopic brain gliomas model
-
Wu Z. P., Gao C. W., Wu Y. G., Zhu Q. S., Chen Y., Liu X., Liu C.,
-
(2009)
Integrative Cancer Therapies
, vol.8
, Issue.1
, pp. 88-92
-
-
Wu, Z.P.1
Gao, C.W.2
Wu, Y.G.3
Zhu, Q.S.4
Chen, Y.5
Liu, X.6
Liu, C.7
-
145
-
-
79953831715
-
2011: The immune hallmarks of cancer
-
Cavallo F., de Giovanni C., Nanni P., Forni G., Lollini P. -L., 2011: the immune hallmarks of cancer Cancer Immunology, Immunotherapy 2011 60 3 319 326
-
(2011)
Cancer Immunology, Immunotherapy
, vol.60
, Issue.3
, pp. 319-326
-
-
Cavallo, F.1
De Giovanni, C.2
Nanni, P.3
Forni, G.4
Lollini, P.-L.5
|