Increased tolerance to artemisinin in plasmodium falciparum is mediated by a quiescence mechanism

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 5, 2010, Pages 1872-1877

  Witkowski, Benoit ^a,b,c   Lelièvre, Joel ^a,b,c,e   Barragán, María José López ^d   Laurent, Victor ^a,b,c   Su, Xin Zhuan ^d   Berry, Antoine ^b,c   Benoit Vical, Françoise ^a,b,c  

^a LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c TOULOUSE UNIVERSITY HOSPITAL   (France)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e Drug Discovery Biology Group   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ DERIVATIVE; ARTESUNATE; CHLOROQUINE; HEAT SHOCK PROTEIN; MEMBRANE PROTEIN;

ANTIMALARIAL DRUG RESISTANCE; ARTICLE; CAMBODIA; CELL CYCLE REGULATION; DEVELOPMENTAL STAGE; DNA SYNTHESIS; DRUG TOLERANCE; ERYTHROCYTE MEMBRANE; FLOW CYTOMETRY; GENE SEQUENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THAILAND;

ANTIMALARIALS; ARTEMISININS; CAMBODIA; DRUG RESISTANCE, BACTERIAL; ERYTHROCYTES; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HUMANS; INHIBITORY CONCENTRATION 50; MALARIA, FALCIPARUM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; THAILAND;

EID: 77951220629     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01636-09     Document Type: Article

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