-
1
-
-
0035315838
-
The anti-malarial artesunate is also active against cancer
-
Efferth T, Dunstan H, Sauerbrey A, Miyachi H, Chitambar CR. The anti-malarial artesunate is also active against cancer. Int J Oncol 2001; 18:767-773.
-
(2001)
Int J Oncol
, vol.18
, pp. 767-773
-
-
Efferth, T.1
Dunstan, H.2
Sauerbrey, A.3
Miyachi, H.4
Chitambar, C.R.5
-
2
-
-
58149316208
-
Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis
-
Nakase I, Gallis B, Takatani-Nakase T, Oh S, Lacoste E, Singh NP, et al. Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis. Cancer Lett 2009; 274:290-298.
-
(2009)
Cancer Lett
, vol.274
, pp. 290-298
-
-
Nakase, I.1
Gallis, B.2
Takatani-Nakase, T.3
Oh, S.4
Lacoste, E.5
Singh, N.P.6
-
3
-
-
1242296302
-
Anticancer and antimalarial efficacy and safety of artemisinin-derived trioxane dimers in rodents
-
Posner GH, McRiner AJ, Paik IH, Sur S, Borstnik K, Xie S, et al. Anticancer and antimalarial efficacy and safety of artemisinin-derived trioxane dimers in rodents. J Med Chem 2004; 47:1299-1301.
-
(2004)
J Med Chem
, vol.47
, pp. 1299-1301
-
-
Posner, G.H.1
McRiner, A.J.2
Paik, I.H.3
Sur, S.4
Borstnik, K.5
Xie, S.6
-
4
-
-
40849097597
-
Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugation
-
Nakase I, Lai H, Singh NP, Sasaki T. Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugation. Int J Pharm 2008; 354:28-33.
-
(2008)
Int J Pharm
, vol.354
, pp. 28-33
-
-
Nakase, I.1
Lai, H.2
Singh, N.P.3
Sasaki, T.4
-
5
-
-
0346655146
-
Drug combinations for malaria: Time to ACT?
-
Duffy PE, Mutabingwa TK. Drug combinations for malaria: time to ACT? Lancet 2004; 363:3-4.
-
(2004)
Lancet
, vol.363
, pp. 3-4
-
-
Duffy, P.E.1
Mutabingwa, T.K.2
-
6
-
-
0021948029
-
Qinghaosu (artemisinin): An antimalarial drug from China
-
Klayman DL. Qinghaosu (artemisinin): an antimalarial drug from China. Science 1985; 228:1049-1055.
-
(1985)
Science
, vol.228
, pp. 1049-1055
-
-
Klayman, D.L.1
-
7
-
-
0037021405
-
Artemisinin: Mechanisms of action, resistance and toxicity
-
Meshnick SR. Artemisinin: mechanisms of action, resistance and toxicity. Int J Parasitol 2002; 32:1655-1660.
-
(2002)
Int J Parasitol
, vol.32
, pp. 1655-1660
-
-
Meshnick, S.R.1
-
8
-
-
59049096024
-
Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression
-
Willoughby JA Sr, Sundar SN, Cheung M, Tin AS, Modiano J, Firestone GL. Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression. J Biol Chem 2009; 284:2203-2213.
-
(2009)
J Biol Chem
, vol.284
, pp. 2203-2213
-
-
Willoughby Sr., J.A.1
Sundar, S.N.2
Cheung, M.3
Tin, A.S.4
Modiano, J.5
Firestone, G.L.6
-
9
-
-
68249142819
-
Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction
-
Stockwin LH, Han B, Yu SX, Hollingshead MG, El Sohly MA, Gul W, et al. Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction. Int J Cancer 2009; 125:1266-1275.
-
(2009)
Int J Cancer
, vol.125
, pp. 1266-1275
-
-
Stockwin, L.H.1
Han, B.2
Yu, S.X.3
Hollingshead, M.G.4
El Sohly, M.A.5
Gul, W.6
-
10
-
-
58549088472
-
Electrochemical activity of holotransferrin and its electrocatalysis- mediated process of artemisinin
-
Cai HH, Cai J, Yang PH. Electrochemical activity of holotransferrin and its electrocatalysis-mediated process of artemisinin. Bioorg Med Chem Lett 2009; 19:863-866.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 863-866
-
-
Cai, H.H.1
Cai, J.2
Yang, P.H.3
-
11
-
-
58549110422
-
Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity
-
Galal AM, Gul W, Slade D, Ross SA, Feng S, Hollingshead MG, et al. Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity. Bioorg Med Chem 2009; 17:741-751.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 741-751
-
-
Galal, A.M.1
Gul, W.2
Slade, D.3
Ross, S.A.4
Feng, S.5
Hollingshead, M.G.6
-
12
-
-
0037435053
-
Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy
-
Posner GH, Paik IH, Sur S, McRiner AJ, Borstnik K, Xie S, et al. Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy. J Med Chem 2003; 46:1060-1065.
-
(2003)
J Med Chem
, vol.46
, pp. 1060-1065
-
-
Posner, G.H.1
Paik, I.H.2
Sur, S.3
McRiner, A.J.4
Borstnik, K.5
Xie, S.6
-
13
-
-
33845919843
-
Biological mechanisms of action of novel C-10 non-acetal trioxane dimers in prostate cancer cell lines
-
Alagbala AA, McRiner AJ, Borstnik K, Labonte T, Chang W, D'Angelo JG, et al. Biological mechanisms of action of novel C-10 non-acetal trioxane dimers in prostate cancer cell lines. J Med Chem 2006; 49:7836-7842.
-
(2006)
J Med Chem
, vol.49
, pp. 7836-7842
-
-
Alagbala, A.A.1
McRiner, A.J.2
Borstnik, K.3
Labonte, T.4
Chang, W.5
D'Angelo, J.G.6
-
14
-
-
44449108773
-
Differential expression of angiogenesis associated genes in prostate cancer bone, liver and lymph node metastases
-
Morrissey C, True LD, Roudier MP, Coleman IM, Hawley S, Nelson PS, et al. Differential expression of angiogenesis associated genes in prostate cancer bone, liver and lymph node metastases. Clin Exp Metastasis 2008; 25:377-388.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 377-388
-
-
Morrissey, C.1
True, L.D.2
Roudier, M.P.3
Coleman, I.M.4
Hawley, S.5
Nelson, P.S.6
-
15
-
-
32044447160
-
Administration of zoledronic acid enhances the effects of docetaxel on growth of prostate cancer in the bone environment
-
Brubaker KD, Brown LG, Vessella RL, Corey E. Administration of zoledronic acid enhances the effects of docetaxel on growth of prostate cancer in the bone environment. BMC Cancer 2006; 6:15.
-
(2006)
BMC Cancer
, vol.6
, pp. 15
-
-
Brubaker, K.D.1
Brown, L.G.2
Vessella, R.L.3
Corey, E.4
-
16
-
-
16444368652
-
Osteoprotegerin in prostate cancer bone metastasis
-
Corey E, Brown LG, Kiefer JA, Quinn JE, Pitts TE, Blair JM, et al. Osteoprotegerin in prostate cancer bone metastasis. Cancer Res 2005; 65:1710-1718.
-
(2005)
Cancer Res
, vol.65
, pp. 1710-1718
-
-
Corey, E.1
Brown, L.G.2
Kiefer, J.A.3
Quinn, J.E.4
Pitts, T.E.5
Blair, J.M.6
-
18
-
-
0028220323
-
Increased androgen receptor activity and altered c-myc expression in prostate cancer cells after long-term androgen deprivation
-
Kokontis J, Takakura K, Hay N, Liao S. Increased androgen receptor activity and altered c-myc expression in prostate cancer cells after long-term androgen deprivation. Cancer Res 1994; 54:1566-1573.
-
(1994)
Cancer Res
, vol.54
, pp. 1566-1573
-
-
Kokontis, J.1
Takakura, K.2
Hay, N.3
Liao, S.4
-
19
-
-
0032537009
-
Increased cell growth and tumorigenicity in human prostate LNCaP cells by overexpression to cyclin D1
-
Chen Y, Martinez LA, LaCava M, Coghlan L, Conti CJ. Increased cell growth and tumorigenicity in human prostate LNCaP cells by overexpression to cyclin D1. Oncogene 1998; 16:1913-1920.
-
(1998)
Oncogene
, vol.16
, pp. 1913-1920
-
-
Chen, Y.1
Martinez, L.A.2
Lacava, M.3
Coghlan, L.4
Conti, C.J.5
-
20
-
-
0034283030
-
Beta-catenin affects androgen receptor transcriptional activity and ligand specificity
-
Truica CI, Byers S, Gelmann EP. Beta-catenin affects androgen receptor transcriptional activity and ligand specificity. Cancer Res 2000; 60:4709-4713.
-
(2000)
Cancer Res
, vol.60
, pp. 4709-4713
-
-
Truica, C.I.1
Byers, S.2
Gelmann, E.P.3
-
21
-
-
0023568485
-
Transferrin receptors in human cancerous tissues
-
Niitsu Y, Kohgo Y, Nishisato T, Kondo H, Kato J, Urushizaki Y, et al. Transferrin receptors in human cancerous tissues. Tohoku J Exp Med 1987; 153:239-243.
-
(1987)
Tohoku J Exp Med
, vol.153
, pp. 239-243
-
-
Niitsu, Y.1
Kohgo, Y.2
Nishisato, T.3
Kondo, H.4
Kato, J.5
Urushizaki, Y.6
-
22
-
-
0020597630
-
Transferrin receptors in human tissues: Their distribution and possible clinical relevance
-
Gatter KC, Brown G, Trowbridge IS, Woolston RE, Mason DY. Transferrin receptors in human tissues: their distribution and possible clinical relevance. J Clin Pathol 1983; 36:539-545.
-
(1983)
J Clin Pathol
, vol.36
, pp. 539-545
-
-
Gatter, K.C.1
Brown, G.2
Trowbridge, I.S.3
Woolston, R.E.4
Mason, D.Y.5
-
23
-
-
0029037444
-
Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin
-
Lai H, Singh NP. Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin. Cancer Lett 1995; 91:41-46.
-
(1995)
Cancer Lett
, vol.91
, pp. 41-46
-
-
Lai, H.1
Singh, N.P.2
-
24
-
-
33846985642
-
Trace elemental analysis of normal, benign hypertrophic and cancerous tissues of the prostate gland using the particle-induced X-ray emission technique
-
Guntupalli JN, Padala S, Gummuluri AV, Muktineni RK, Byreddy SR, Sreerama L, et al. Trace elemental analysis of normal, benign hypertrophic and cancerous tissues of the prostate gland using the particle-induced X-ray emission technique. Eur J Cancer Prev 2007; 16:108-115.
-
(2007)
Eur J Cancer Prev
, vol.16
, pp. 108-115
-
-
Guntupalli, J.N.1
Padala, S.2
Gummuluri, A.V.3
Muktineni, R.K.4
Byreddy, S.R.5
Sreerama, L.6
-
25
-
-
4444383530
-
Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron
-
Efferth T, Benakis A, Romero MR, Tomicic M, Rauh R, Steinbach D, et al. Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron. Free Radic Biol Med 2004; 37:998-1009.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 998-1009
-
-
Efferth, T.1
Benakis, A.2
Romero, M.R.3
Tomicic, M.4
Rauh, R.5
Steinbach, D.6
-
26
-
-
54049085042
-
SPC3042: A proapoptotic survivin inhibitor
-
Hansen JB, Fisker N, Westergaard M, Kjaerulff LS, Hansen HF, Thrue CA, et al. SPC3042: a proapoptotic survivin inhibitor. Mol Cancer Ther 2008; 7:2736-2745.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2736-2745
-
-
Hansen, J.B.1
Fisker, N.2
Westergaard, M.3
Kjaerulff, L.S.4
Hansen, H.F.5
Thrue, C.A.6
-
27
-
-
0030746636
-
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
-
Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997; 3:917-921.
-
(1997)
Nat Med
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.C.3
-
28
-
-
0029071657
-
D-type cyclins
-
Sherr CJ. D-type cyclins. Trends Biochem Sci 1995; 20:187-190.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 187-190
-
-
Sherr, C.J.1
-
29
-
-
0034594915
-
Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death
-
Suzuki A, Ito T, Kawano H, Hayashida M, Hayasaki Y, Tsutomi Y, et al. Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death. Oncogene 2000; 19:1346-1353.
-
(2000)
Oncogene
, vol.19
, pp. 1346-1353
-
-
Suzuki, A.1
Ito, T.2
Kawano, H.3
Hayashida, M.4
Hayasaki, Y.5
Tsutomi, Y.6
-
30
-
-
18644366530
-
Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype
-
Williams K, Fernandez S, Stien X, Ishii K, Love HD, Lau YF, et al. Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype. Prostate 2005; 63:369-384.
-
(2005)
Prostate
, vol.63
, pp. 369-384
-
-
Williams, K.1
Fernandez, S.2
Stien, X.3
Ishii, K.4
Love, H.D.5
Lau, Y.F.6
-
32
-
-
46449088590
-
Beta-catenin mediates alteration in cell proliferation, motility and invasion of prostate cancer cells by differential expression of E-cadherin and protein kinase D1
-
Syed V, Mak P, Du C, Balaji KC. Beta-catenin mediates alteration in cell proliferation, motility and invasion of prostate cancer cells by differential expression of E-cadherin and protein kinase D1. J Cell Biochem 2008; 104:82-95.
-
(2008)
J Cell Biochem
, vol.104
, pp. 82-95
-
-
Syed, V.1
Mak, P.2
Du, C.3
Balaji, K.C.4
-
33
-
-
0029865240
-
Two androgen response regions cooperate in steroid hormone regulated activity of the prostate-specific antigen promoter
-
Cleutjens KB, van Eekelen CC, van Der Korput HA, Brinkmann AO, Trapman J. Two androgen response regions cooperate in steroid hormone regulated activity of the prostate-specific antigen promoter. J Biol Chem 1996; 271:6379-6388.
-
(1996)
J Biol Chem
, vol.271
, pp. 6379-6388
-
-
Cleutjens, K.B.1
Van Eekelen, C.C.2
Van Der Korput, H.A.3
Brinkmann, A.O.4
Trapman, J.5
|