-
1
-
-
2342550633
-
Novel therapeutic strategies for androgen- independent prostate cancer: An update
-
Assikis VJ, Simons JW. Novel therapeutic strategies for androgen- independent prostate cancer: An update. Semin Oncol 2004; 31(2 Suppl 4): 26-32.
-
(2004)
Semin Oncol
, vol.31
, Issue.2 SUPPL. 4
, pp. 26-32
-
-
Assikis, V.J.1
Simons, J.W.2
-
2
-
-
0032323546
-
Management of hormone refractory prostate cancer: Current standards and future prospects
-
Oh WK, Kantoff PW. Management of hormone refractory prostate cancer: current standards and future prospects. J Urol 1998; 160(4): 1220-9.
-
(1998)
J Urol
, vol.160
, Issue.4
, pp. 1220-1229
-
-
Oh, W.K.1
Kantoff, P.W.2
-
3
-
-
0842281645
-
Cell death: Critical control points
-
Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004; 116(2): 205-19.
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
4
-
-
0036463649
-
Apoptosis-based therapies
-
Reed JC. Apoptosis-based therapies. Nat Rev Drug Discov 2002; 1(2): 111-21.
-
(2002)
Nat Rev Drug Discov
, vol.1
, Issue.2
, pp. 111-121
-
-
Reed, J.C.1
-
5
-
-
0033288336
-
Mitochondrial control of apoptosis: An overview
-
Kroemer G. Mitochondrial control of apoptosis: an overview. Biochem Soc Symp 1999; 66: 1-15.
-
(1999)
Biochem Soc Symp
, vol.66
, pp. 1-15
-
-
Kroemer, G.1
-
6
-
-
0036060493
-
State-of-the-art treatment of metastatic hormone-refractory prostate cancer
-
Goodin S, Rao KV, DiPaola RS. State-of-the-art treatment of metastatic hormone-refractory prostate cancer. Oncologist 2002; 7(4): 360-70.
-
(2002)
Oncologist
, vol.7
, Issue.4
, pp. 360-370
-
-
Goodin, S.1
Rao, K.V.2
Dipaola, R.S.3
-
8
-
-
0038786580
-
Apoptosis-targeted therapies for cancer
-
Reed JC. Apoptosis-targeted therapies for cancer. Cancer Cell 2003; 3(1): 17-22.
-
(2003)
Cancer Cell
, vol.3
, Issue.1
, pp. 17-22
-
-
Reed, J.C.1
-
9
-
-
0035902166
-
Cancer genetics
-
Ponder BA. Cancer genetics. Nature 2001; 411: 336-341.
-
(2001)
Nature
, vol.411
, pp. 336-341
-
-
Ponder, B.A.1
-
10
-
-
0032779935
-
Molecular regulation of cell death and therapeutic strategies for cell death induction in prostate carcinoma
-
Gjertsen BT, Logothetis CJ, McDonnell TJ. Molecular regulation of cell death and therapeutic strategies for cell death induction in prostate carcinoma. Cancer Metastasis Rev 1999; 17: 345-51
-
(1999)
Cancer Metastasis Rev
, vol.17
, pp. 345-351
-
-
Gjertsen, B.T.1
Logothetis, C.J.2
McDonnell, T.J.3
-
11
-
-
0036207583
-
Self-assembly of a virus- mimicking nanostructure system for efficient tumor-targeted gene delivery
-
Xu L, Frederik P, Pirollo KF, et al. Self-assembly of a virus- mimicking nanostructure system for efficient tumor-targeted gene delivery. Hum Gene Ther 2002; 13(3): 469-81.
-
(2002)
Hum Gene Ther
, vol.13
, Issue.3
, pp. 469-481
-
-
Xu, L.1
Frederik, P.2
Pirollo, K.F.3
-
12
-
-
0031918223
-
BCL-2 family: Regulators of cell death
-
Chao DT, Korsmeyer SJ. BCL-2 family: regulators of cell death. Ann Rev Immun 1998; 16: 395-419.
-
(1998)
Ann Rev Immun
, vol.16
, pp. 395-419
-
-
Chao, D.T.1
Korsmeyer, S.J.2
-
13
-
-
0031464448
-
Bcl-2 family proteins: Regulators of apoptosis and chemoresistance in hematologic malignancies
-
Reed JC. Bcl-2 family proteins: regulators of apoptosis and chemoresistance in hematologic malignancies. Semin Hematol 1997; 34(4 Suppl 5): 9-19.
-
(1997)
Semin Hematol
, vol.34
, Issue.4 SUPPL. 5
, pp. 9-19
-
-
Reed, J.C.1
-
14
-
-
0030979773
-
Double identity for proteins of the Bcl-2 family
-
Reed JC. Double identity for proteins of the Bcl-2 family. Nature 1997; 387(6635): 773-6.
-
(1997)
Nature
, vol.387
, Issue.6635
, pp. 773-776
-
-
Reed, J.C.1
-
16
-
-
0033119372
-
BCL-2 gene family and the regulation of programmed cell death
-
Korsmeyer SJ. BCL-2 gene family and the regulation of programmed cell death. Cancer Res 1999; 59(7 Suppl): 1693s-700s.
-
(1999)
Cancer Res
, vol.59
, Issue.7 SUPPL.
-
-
Korsmeyer, S.J.1
-
17
-
-
68149112387
-
Mimicking the BH3 domain to kill cancer cells
-
Chonghaile TN, Letai A. Mimicking the BH3 domain to kill cancer cells. Oncogene 2008; 27 Suppl 1: S149-57.
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Chonghaile, T.N.1
Letai, A.2
-
18
-
-
1542616703
-
Proteins of the bcl-2 family in apoptosis signalling: From mechanistic insights to therapeutic opportunities
-
Chan SL, Yu VC. Proteins of the bcl-2 family in apoptosis signalling: from mechanistic insights to therapeutic opportunities. Clin Exp Pharmacol Physiol 2004; 31(3): 119-28.
-
(2004)
Clin Exp Pharmacol Physiol
, vol.31
, Issue.3
, pp. 119-128
-
-
Chan, S.L.1
Yu, V.C.2
-
19
-
-
68149154728
-
BH3-only proteins and their roles in programmed cell death
-
Giam M, Huang DC, Bouillet P. BH3-only proteins and their roles in programmed cell death. Oncogene 2008; 27 Suppl 1: S128-36.
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Giam, M.1
Huang, D.C.2
Bouillet, P.3
-
20
-
-
17644421083
-
Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy
-
Tan TT, Degenhardt K, Nelson DA, et al. Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy. Cancer Cell 2005; 7(3): 227-38.
-
(2005)
Cancer Cell
, vol.7
, Issue.3
, pp. 227-238
-
-
Tan, T.T.1
Degenhardt, K.2
Nelson, D.A.3
-
21
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
Adams JM, Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 2007; 26(9): 1324-37.
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
22
-
-
79961205336
-
Programmed cell death and survival pathways in prostate cancer cells
-
Lee EC, Tenniswood M. Programmed cell death and survival pathways in prostate cancer cells. Arch Androl 2004; 50(1): 27-32.
-
(2004)
Arch Androl
, vol.50
, Issue.1
, pp. 27-32
-
-
Lee, E.C.1
Tenniswood, M.2
-
23
-
-
0035500410
-
Apoptosis and cancer chemotherapy
-
Makin G, Dive C. Apoptosis and cancer chemotherapy. Trends Cell Biol 2001; 11(11): S22-6.
-
(2001)
Trends Cell Biol
, vol.11
, Issue.11
-
-
Makin, G.1
Dive, C.2
-
24
-
-
0036040031
-
The anti-apoptotic genes Bcl- X(L) and Bcl-2 are over-expressed and contribute to chemo- resistance of non-proliferating leukaemic CD34+ cells
-
Konopleva M, Zhao S, Hu W, et al. The anti-apoptotic genes Bcl- X(L) and Bcl-2 are over-expressed and contribute to chemo- resistance of non-proliferating leukaemic CD34+ cells. Br J Haematol 2002; 118(2): 521-34.
-
(2002)
Br J Haematol
, vol.118
, Issue.2
, pp. 521-534
-
-
Konopleva, M.1
Zhao, S.2
Hu, W.3
-
25
-
-
0029983253
-
Expression of bcl-2 and the progression of human and rodent prostatic cancers
-
Furuya Y, Krajewski S, Epstein JI, Reed JC, Isaacs JT. Expression of bcl-2 and the progression of human and rodent prostatic cancers. Clin Cancer Res 1996; 2(2): 389-98.
-
(1996)
Clin Cancer Res
, vol.2
, Issue.2
, pp. 389-398
-
-
Furuya, Y.1
Krajewski, S.2
Epstein, J.I.3
Reed, J.C.4
Isaacs, J.T.5
-
26
-
-
0029919668
-
Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers
-
Krajewska M, Krajewski S, Epstein JI, et al. Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. Am J Pathol 1996; 148(5): 1567-76.
-
(1996)
Am J Pathol
, vol.148
, Issue.5
, pp. 1567-1576
-
-
Krajewska, M.1
Krajewski, S.2
Epstein, J.I.3
-
27
-
-
0033965759
-
BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma
-
Beale PJ, Rogers P, Boxall F, Sharp SY, Kelland LR. BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma. Br J Cancer 2000; 82(2): 436-40.
-
(2000)
Br J Cancer
, vol.82
, Issue.2
, pp. 436-440
-
-
Beale, P.J.1
Rogers, P.2
Boxall, F.3
Sharp, S.Y.4
Kelland, L.R.5
-
28
-
-
0036893309
-
Bcl-2 has differing effects on the sensitivity of breast cancer cells depending on the antineoplastic drug used
-
Del Bufalo D, Biroccio A, Trisciuoglio D, et al. Bcl-2 has differing effects on the sensitivity of breast cancer cells depending on the antineoplastic drug used. Eur J Cancer 2002; 38(18): 2455-62.
-
(2002)
Eur J Cancer
, vol.38
, Issue.18
, pp. 2455-2462
-
-
Del Bufalo, D.1
Biroccio, A.2
Trisciuoglio, D.3
-
29
-
-
0032998309
-
Overcoming bcl-2- and p53-mediated resis- tance in prostate cancer
-
DiPaola RS, Aisner J. Overcoming bcl-2- and p53-mediated resis- tance in prostate cancer. Sem Oncol 1999; 26(1 Suppl 2): 112-6.
-
(1999)
Sem Oncol
, vol.26
, Issue.1 SUPPL. 2
, pp. 112-116
-
-
Dipaola, R.S.1
Aisner, J.2
-
30
-
-
10744229243
-
Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance
-
Ferlini C, Raspaglio G, Mozzetti S, et al. Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance. Mol Pharmacol 2003; 64(1): 51-8.
-
(2003)
Mol Pharmacol
, vol.64
, Issue.1
, pp. 51-58
-
-
Ferlini, C.1
Raspaglio, G.2
Mozzetti, S.3
-
31
-
-
0030634474
-
Bcl-2 family proteins: Strategies for overcoming chemoresistance in cancer
-
Reed JC. Bcl-2 family proteins: strategies for overcoming chemoresistance in cancer. Adv Pharmacol 1997; 41: 501-32.
-
(1997)
Adv Pharmacol
, vol.41
, pp. 501-532
-
-
Reed, J.C.1
-
32
-
-
0034352334
-
Regulation of Bcl-xL: A little bit of this and a little bit of STAT
-
Grad JM, Zeng XR, Boise LH. Regulation of Bcl-xL: a little bit of this and a little bit of STAT. Curr Opin Oncol 2000; 12(6): 543-9.
-
(2000)
Curr Opin Oncol
, vol.12
, Issue.6
, pp. 543-549
-
-
Grad, J.M.1
Zeng, X.R.2
Boise, L.H.3
-
33
-
-
0034326272
-
Bcl-xL in prostate cancer cells: Effects of overexpression and down- regulation on chemosensitivity
-
Lebedeva I, Rando R, Ojwang J, Cossum P, Stein CA. Bcl-xL in prostate cancer cells: effects of overexpression and down- regulation on chemosensitivity. Cancer Res 2000; 60(21): 6052-60.
-
(2000)
Cancer Res
, vol.60
, Issue.21
, pp. 6052-6060
-
-
Lebedeva, I.1
Rando, R.2
Ojwang, J.3
Cossum, P.4
Stein, C.A.5
-
34
-
-
5244224827
-
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
-
Muchmore SW, Sattler M, Liang H, et al. X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature 1996; 381(6580): 335-41.
-
(1996)
Nature
, vol.381
, Issue.6580
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
-
35
-
-
0036405323
-
Antisense therapy: Current status in prostate cancer and other malignancies
-
Gleave M, Miyake H, Zangemeister-Wittke U, Jansen B. Antisense therapy: current status in prostate cancer and other malignancies. Cancer Metastasis Rev 2002; 21(1): 79-92.
-
(2002)
Cancer Metastasis Rev
, vol.21
, Issue.1
, pp. 79-92
-
-
Gleave, M.1
Miyake, H.2
Zangemeister-Wittke, U.3
Jansen, B.4
-
36
-
-
0034659691
-
Inhibition of progression to androgen-independence by combined adjuvant treatment with antisense BCL-XL and antisense Bcl-2 oligonucleotides plus taxol after castration in the Shionogi tumor model
-
Miyake H, Monia BP, Gleave ME. Inhibition of progression to androgen-independence by combined adjuvant treatment with antisense BCL-XL and antisense Bcl-2 oligonucleotides plus taxol after castration in the Shionogi tumor model. Int J Cancer 2000; 86(6): 855-62.
-
(2000)
Int J Cancer
, vol.86
, Issue.6
, pp. 855-862
-
-
Miyake, H.1
Monia, B.P.2
Gleave, M.E.3
-
37
-
-
0037382584
-
Antisense targets to enhance hormone and cytotoxic therapies in advanced prostate cancer
-
Gleave M, Nelson C, Chi K. Antisense targets to enhance hormone and cytotoxic therapies in advanced prostate cancer. Curr Drug Targets 2003; 4(3): 209-21.
-
(2003)
Curr Drug Targets
, vol.4
, Issue.3
, pp. 209-221
-
-
Gleave, M.1
Nelson, C.2
Chi, K.3
-
38
-
-
0030632191
-
Bcl-2 family proteins and the hormonal control of cell life and death in normalcy and neoplasia
-
Reed JC. Bcl-2 family proteins and the hormonal control of cell life and death in normalcy and neoplasia. Vitam Hormones 1997; 53: 99-138.
-
(1997)
Vitam Hormones
, vol.53
, pp. 99-138
-
-
Reed, J.C.1
-
39
-
-
18144429102
-
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis
-
Han J, Goldstein LA, Gastman BR, Rabinovitz A, Rabinowich H. Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis. J Biol Chem 2005; 280(16): 16383-92.
-
(2005)
J Biol Chem
, vol.280
, Issue.16
, pp. 16383-92
-
-
Han, J.1
Goldstein, L.A.2
Gastman, B.R.3
Rabinovitz, A.4
Rabinowich, H.5
-
40
-
-
2442450642
-
Expression and prognostic relevance of Mcl-1 in breast cancer
-
O'Driscoll L, Cronin D, Kennedy SM, et al. Expression and prognostic relevance of Mcl-1 in breast cancer. Anticancer Res 2004; 24(2A): 473-82.
-
(2004)
Anticancer Res
, vol.24
, Issue.2 A
, pp. 473-482
-
-
O'Driscoll, L.1
Cronin, D.2
Kennedy, S.M.3
-
41
-
-
4544348358
-
Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia
-
Johnston JB, Paul JT, Neufeld NJ, et al. Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia. Leuk Lymphoma 2004; 45(10): 2017-27.
-
(2004)
Leuk Lymphoma
, vol.45
, Issue.10
, pp. 2017-2027
-
-
Johnston, J.B.1
Paul, J.T.2
Neufeld, N.J.3
-
42
-
-
9244237013
-
The imbalance between Bim and Mcl-1 expression controls the survival of human myeloma cells
-
Gomez-Bougie P, Bataille R, Amiot M. The imbalance between Bim and Mcl-1 expression controls the survival of human myeloma cells. Eur J Immunol 2004; 34(11): 3156-64.
-
(2004)
Eur J Immunol
, vol.34
, Issue.11
, pp. 3156-3164
-
-
Gomez-Bougie, P.1
Bataille, R.2
Amiot, M.3
-
43
-
-
46749085910
-
Mcl-1 is regulated by IL- 6 and mediates the survival activity of the cytokine in a model of late stage prostate carcinoma
-
Cavarretta IT, Neuwirt H, Zaki MH, et al. Mcl-1 is regulated by IL- 6 and mediates the survival activity of the cytokine in a model of late stage prostate carcinoma. Adv Exp Med Biol 2008; 617: 547-55.
-
(2008)
Adv Exp Med Biol
, vol.617
, pp. 547-555
-
-
Cavarretta, I.T.1
Neuwirt, H.2
Zaki, M.H.3
-
44
-
-
1942440451
-
Androgen receptor expression in relation to apoptosis and the expression of cell cycle related proteins in prostate cancer
-
Amirghofran Z, Monabati A, Gholijani N. Androgen receptor expression in relation to apoptosis and the expression of cell cycle related proteins in prostate cancer. Pathol Oncol Res 2004; 10(1): 37-41.
-
(2004)
Pathol Oncol Res
, vol.10
, Issue.1
, pp. 37-41
-
-
Amirghofran, Z.1
Monabati, A.2
Gholijani, N.3
-
45
-
-
0034722884
-
Bcl-2 family proteins as targets for anticancer drug design
-
Huang Z. Bcl-2 family proteins as targets for anticancer drug design. Oncogene 2000; 19(56): 6627-31.
-
(2000)
Oncogene
, vol.19
, Issue.56
, pp. 6627-6631
-
-
Huang, Z.1
-
46
-
-
0030795866
-
Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death
-
Simonian PL, Grillot DA, Nunez G. Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death. Blood 1997; 90(3): 1208-16.
-
(1997)
Blood
, vol.90
, Issue.3
, pp. 1208-1216
-
-
Simonian, P.L.1
Grillot, D.A.2
Nunez, G.3
-
47
-
-
0031755585
-
Bcl-2 but not p53 expression is associated with resistance to chemotherapy in advanced breast cancer
-
Bonetti A, Zaninelli M, Leone R, et al. bcl-2 but not p53 expression is associated with resistance to chemotherapy in advanced breast cancer. Clin Cancer Res 1998; 4(10): 2331-6.
-
(1998)
Clin Cancer Res
, vol.4
, Issue.10
, pp. 2331-2336
-
-
Bonetti, A.1
Zaninelli, M.2
Leone, R.3
-
48
-
-
0036568524
-
Bcl-X(L) is a chemoresistance factor in human melanoma cells that can be inhibited by antisense therapy
-
Heere-Ress E, Thallinger C, Lucas T, et al. Bcl-X(L) is a chemoresistance factor in human melanoma cells that can be inhibited by antisense therapy. Int J Cancer 2002; 99(1): 29-34.
-
(2002)
Int J Cancer
, vol.99
, Issue.1
, pp. 29-34
-
-
Heere-Ress, E.1
Thallinger, C.2
Lucas, T.3
-
49
-
-
3042522791
-
The androgen receptor in hormone-refractory prostate cancer: Relevance of different mechanisms of androgen receptor signaling (Review)
-
Cronauer MV, Schulz WA, Burchardt T, et al. The androgen receptor in hormone-refractory prostate cancer: relevance of different mechanisms of androgen receptor signaling (Review). Int J Oncol 2003; 23(4): 1095-102.
-
(2003)
Int J Oncol
, vol.23
, Issue.4
, pp. 1095-1102
-
-
Cronauer, M.V.1
Schulz, W.A.2
Burchardt, T.3
-
50
-
-
0032428061
-
Management of hormone-sensitive and hormone- refractory metastatic prostate cancer
-
Rago R. Management of hormone-sensitive and hormone- refractory metastatic prostate cancer. Cancer Control 1998; 5(6): 513-21.
-
(1998)
Cancer Control
, vol.5
, Issue.6
, pp. 513-521
-
-
Rago, R.1
-
51
-
-
1042280304
-
Molecular therapy intervention prospects in prostate cancer
-
Rege YD, Rangnekar VM. Molecular therapy intervention prospects in prostate cancer. Curr Pharm Design 2004; 10(5): 523-30.
-
(2004)
Curr Pharm Design
, vol.10
, Issue.5
, pp. 523-530
-
-
Rege, Y.D.1
Rangnekar, V.M.2
-
52
-
-
0036319255
-
Bcl-2-related antisense therapy
-
Gutierrez-Puente Y, Zapata-Benavides P, Tari AM, Lopez-Berestein G. Bcl-2-related antisense therapy. Semin Oncol 2002; 29(3 Suppl 11): 71-6.
-
(2002)
Semin Oncol
, vol.29
, Issue.3 SUPPL. 11
, pp. 71-76
-
-
Gutierrez-Puente, Y.1
Zapata-Benavides, P.2
Tari, A.M.3
Lopez-Berestein, G.4
-
53
-
-
0035570021
-
Novel therapeutic strategy for advanced prostate cancer using antisense oligodeoxynucleotides targeting anti-apoptotic genes upregulated after androgen withdrawal to delay androgen-independent progression and enhance chemosensitivity
-
Miyake H, Hara I, Kamidono S, Gleave ME. Novel therapeutic strategy for advanced prostate cancer using antisense oligodeoxynucleotides targeting anti-apoptotic genes upregulated after androgen withdrawal to delay androgen-independent progression and enhance chemosensitivity. Int J Urol 2001; 8(7): 337-49.
-
(2001)
Int J Urol
, vol.8
, Issue.7
, pp. 337-349
-
-
Miyake, H.1
Hara, I.2
Kamidono, S.3
Gleave, M.E.4
-
54
-
-
0036531791
-
Antisense RNA down-regulation of bcl-xL Expression in prostate cancer cells leads to diminished rates of cellular proliferation and resistance to cytotoxic chemotherapeutic agents
-
Vilenchik M, Raffo AJ, Benimetskaya L, Shames D, Stein CA. Antisense RNA down-regulation of bcl-xL Expression in prostate cancer cells leads to diminished rates of cellular proliferation and resistance to cytotoxic chemotherapeutic agents. Cancer Res 2002; 62(7): 2175-83.
-
(2002)
Cancer Res
, vol.62
, Issue.7
, pp. 2175-2183
-
-
Vilenchik, M.1
Raffo, A.J.2
Benimetskaya, L.3
Shames, D.4
Stein, C.A.5
-
55
-
-
0348014548
-
Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity
-
Del Bufalo D, Trisciuoglio D, Scarsella M, Zangemeister-Wittke U, Zupi G. Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity. Oncogene 2003; 22(52): 8441-7.
-
(2003)
Oncogene
, vol.22
, Issue.52
, pp. 8441-8447
-
-
Del Bufalo, D.1
Trisciuoglio, D.2
Scarsella, M.3
Zangemeister-Wittke, U.4
Zupi, G.5
-
56
-
-
0035925537
-
Activity of a novel bcl- 2/bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins
-
Gautschi O, Tschopp S, Olie RA, et al. Activity of a novel bcl- 2/bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins. J Nat Cancer Inst 2001; 93(6): 463-71.
-
(2001)
J Nat Cancer Inst
, vol.93
, Issue.6
, pp. 463-471
-
-
Gautschi, O.1
Tschopp, S.2
Olie, R.A.3
-
57
-
-
0036730430
-
Bcl-xL antisense oligonucleotides chemosensitize human glioblastoma cells
-
Guensberg P, Wacheck V, Lucas T, et al. Bcl-xL antisense oligonucleotides chemosensitize human glioblastoma cells. Chemotherapy 2002; 48(4): 189-95.
-
(2002)
Chemotherapy
, vol.48
, Issue.4
, pp. 189-195
-
-
Guensberg, P.1
Wacheck, V.2
Lucas, T.3
-
58
-
-
0036986695
-
BcI-xL antisense treatment sensitizes Bcl-xL-overexpressing squamous cell carcinoma cells to carboplatin
-
Itoh M, Noutomi T, Chiba H, Mizuguchi J. BcI-xL antisense treatment sensitizes Bcl-xL-overexpressing squamous cell carcinoma cells to carboplatin. Oral Oncol 2002; 38(8): 752-6.
-
(2002)
Oral Oncol
, vol.38
, Issue.8
, pp. 752-756
-
-
Itoh, M.1
Noutomi, T.2
Chiba, H.3
Mizuguchi, J.4
-
59
-
-
0036830417
-
Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide
-
Simoes-Wust AP, Schurpf T, Hall J, Stahel RA, Zangemeister-Wittke U. Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide. Breast Cancer Res Treat 2002; 76(2): 157-66.
-
(2002)
Breast Cancer Res Treat
, vol.76
, Issue.2
, pp. 157-166
-
-
Simoes-Wust, A.P.1
Schurpf, T.2
Hall, J.3
Stahel, R.A.4
Zangemeister-Wittke, U.5
-
60
-
-
0034784534
-
Bcl-2 antisense oligonucleotides chemosensitize human gastric cancer in a SCID mouse xenotransplantation model
-
Wacheck V, Heere-Ress E, Halaschek-Wiener J, et al. Bcl-2 antisense oligonucleotides chemosensitize human gastric cancer in a SCID mouse xenotransplantation model. J Mol Med 2001; 79(10): 587-93.
-
(2001)
J Mol Med
, vol.79
, Issue.10
, pp. 587-593
-
-
Wacheck, V.1
Heere-Ress, E.2
Halaschek-Wiener, J.3
-
61
-
-
74049092271
-
Targeting the Bcl-2
-
Patel MP, Masood A, Patel PS, Chanan-Khan AA. Targeting the Bcl-2. Curr Opin Oncol 2009; 21(6): 516-23.
-
(2009)
Curr Opin Oncol
, vol.21
, Issue.6
, pp. 516-523
-
-
Patel, M.P.1
Masood, A.2
Patel, P.S.3
Chanan-Khan, A.A.4
-
62
-
-
67650360358
-
Docetaxel plus oblimersen sodium (Bcl-2 antisense oligonucleotide): An EORTC multicenter, randomized phase II study in patients with castration- resistant prostate cancer
-
Sternberg CN, Dumez H, Van Poppel H, et al. Docetaxel plus oblimersen sodium (Bcl-2 antisense oligonucleotide): an EORTC multicenter, randomized phase II study in patients with castration- resistant prostate cancer. Ann Oncol 2009; 20(7): 1264-9.
-
(2009)
Ann Oncol
, vol.20
, Issue.7
, pp. 1264-1269
-
-
Sternberg, C.N.1
Dumez, H.2
van Poppel, H.3
-
63
-
-
36448982918
-
Oblimersen for the treatment of patients with chronic lymphocytic leukemia
-
Cheson BD. Oblimersen for the treatment of patients with chronic lymphocytic leukemia. Ther Clin Risk Manag 2007; 3(5): 855-70.
-
(2007)
Ther Clin Risk Manag
, vol.3
, Issue.5
, pp. 855-870
-
-
Cheson, B.D.1
-
64
-
-
28844437366
-
Mcl-1 overexpression in hepatocellular carcinoma: A potential target for antisense therapy
-
Sieghart W, Losert D, Strommer S, et al. Mcl-1 overexpression in hepatocellular carcinoma: A potential target for antisense therapy. J Hepatol 2006; 44(1): 151-7.
-
(2006)
J Hepatol
, vol.44
, Issue.1
, pp. 151-157
-
-
Sieghart, W.1
Losert, D.2
Strommer, S.3
-
65
-
-
33751112991
-
Antisense targeting of Mcl-1 has therapeutic potential in gastric cancer
-
Zangemeister-Wittke U, Huwiler A. Antisense targeting of Mcl-1 has therapeutic potential in gastric cancer. Cancer Biol Ther 2006; 5(10): 1355-6.
-
(2006)
Cancer Biol Ther
, vol.5
, Issue.10
, pp. 1355-1356
-
-
Zangemeister-Wittke, U.1
Huwiler, A.2
-
66
-
-
33947579975
-
Identification of MCL1 as a novel target in neoplastic mast cells in systemic mastocytosis: Inhibition of mast cell survival by MCL1 antisense oligonucleotides and synergism with PKC412
-
Aichberger KJ, Mayerhofer M, Gleixner KV, et al. Identification of MCL1 as a novel target in neoplastic mast cells in systemic mastocytosis: inhibition of mast cell survival by MCL1 antisense oligonucleotides and synergism with PKC412. Blood 2007; 109(7): 3031-41.
-
(2007)
Blood
, vol.109
, Issue.7
, pp. 3031-3041
-
-
Aichberger, K.J.1
Mayerhofer, M.2
Gleixner, K.V.3
-
67
-
-
33751080104
-
Mcl-1 is a relevant molecular target for antisense oligonucleotide strategies in gastric cancer cells
-
Wacheck V, Cejka D, Sieghart W, et al. Mcl-1 is a relevant molecular target for antisense oligonucleotide strategies in gastric cancer cells. Cancer Biol Ther 2006; 5(10): 1348-54.
-
(2006)
Cancer Biol Ther
, vol.5
, Issue.10
, pp. 1348-1354
-
-
Wacheck, V.1
Cejka, D.2
Sieghart, W.3
-
68
-
-
28044468839
-
A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells
-
Yamanaka K, Rocchi P, Miyake H, et al. A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells. Mol Cancer Ther 2005; 4(11): 1689-98.
-
(2005)
Mol Cancer Ther
, vol.4
, Issue.11
, pp. 1689-1698
-
-
Yamanaka, K.1
Rocchi, P.2
Miyake, H.3
-
69
-
-
22944436158
-
Mcl-1 blocks radiation- induced apoptosis and inhibits clonogenic cell death
-
Skvara H, Thallinger C, Wacheck V, et al. Mcl-1 blocks radiation- induced apoptosis and inhibits clonogenic cell death. Anticancer Res 2005; 25(4): 2697-703.
-
(2005)
Anticancer Res
, vol.25
, Issue.4
, pp. 2697-2703
-
-
Skvara, H.1
Thallinger, C.2
Wacheck, V.3
-
70
-
-
33750051632
-
Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction
-
Schulze-Bergkamen H, Fleischer B, Schuchmann M, et al. Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction. BMC Cancer 2006; 6: 232.
-
(2006)
BMC Cancer
, vol.6
, pp. 232
-
-
Schulze-Bergkamen, H.1
Fleischer, B.2
Schuchmann, M.3
-
71
-
-
57349096726
-
NaCl induced high cationic hydroxyethylated cholesterol-based nanoparticle-mediated synthetic small interfering RNA transfer into prostate carcinoma PC-3 cells
-
Hattori Y, Yoshizawa T, Koga K, Maitani Y. NaCl induced high cationic hydroxyethylated cholesterol-based nanoparticle-mediated synthetic small interfering RNA transfer into prostate carcinoma PC-3 cells. Biol Pharm Bull 2008; 31(12): 2294-301.
-
(2008)
Biol Pharm Bull
, vol.31
, Issue.12
, pp. 2294-2301
-
-
Hattori, Y.1
Yoshizawa, T.2
Koga, K.3
Maitani, Y.4
-
72
-
-
51849157031
-
Inducing apoptosis and enhancing chemosensitivity to gemcitabine via RNA interference targeting Mcl-1 gene in pancreatic carcinoma cell
-
Wei SH, Dong K, Lin F, et al. Inducing apoptosis and enhancing chemosensitivity to gemcitabine via RNA interference targeting Mcl-1 gene in pancreatic carcinoma cell. Cancer Chemother Pharmacol 2008; 62(6): 1055-64.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, Issue.6
, pp. 1055-1064
-
-
Wei, S.H.1
Dong, K.2
Lin, F.3
-
73
-
-
36549012305
-
Apoptotic and autophagic responses to Bcl-2 inhibition and photodamage
-
Kessel D, Arroyo AS. Apoptotic and autophagic responses to Bcl-2 inhibition and photodamage. Photochem Photobiol Sci 2007; 6(12): 1290-5.
-
(2007)
Photochem Photobiol Sci
, vol.6
, Issue.12
, pp. 1290-1295
-
-
Kessel, D.1
Arroyo, A.S.2
-
74
-
-
34250816328
-
Up- regulation of Bcl-2 is required for the progression of prostate cancer cells from an androgen-dependent to an androgen- independent growth stage
-
Lin Y, Fukuchi J, Hiipakka RA, Kokontis JM, Xiang J. Up- regulation of Bcl-2 is required for the progression of prostate cancer cells from an androgen-dependent to an androgen- independent growth stage. Cell Res 2007; 17(6): 531-6.
-
(2007)
Cell Res
, vol.17
, Issue.6
, pp. 531-536
-
-
Lin, Y.1
Fukuchi, J.2
Hiipakka, R.A.3
Kokontis, J.M.4
Xiang, J.5
-
75
-
-
66149150498
-
Multitarget therapy of malignant cancers by the head-to-tail tandem array multiple shRNAs expression system
-
Cheng TL, Teng CF, Tsai WH, et al. Multitarget therapy of malignant cancers by the head-to-tail tandem array multiple shRNAs expression system. Cancer Gene Ther 2009; 16(6): 516-31.
-
(2009)
Cancer Gene Ther
, vol.16
, Issue.6
, pp. 516-531
-
-
Cheng, T.L.1
Teng, C.F.2
Tsai, W.H.3
-
76
-
-
27244432205
-
MicroRNAs as oncogenes and tumor suppressors
-
Chen CZ. MicroRNAs as oncogenes and tumor suppressors. N Engl J Med 2005; 353(17): 1768-71.
-
(2005)
N Engl J Med
, vol.353
, Issue.17
, pp. 1768-1771
-
-
Chen, C.Z.1
-
77
-
-
33846188098
-
MicroRNAs as oncogenes and tumor suppressors
-
Zhang B, Pan X, Cobb GP, Anderson TA. microRNAs as oncogenes and tumor suppressors. Dev Biol 2007; 302(1): 1-12.
-
(2007)
Dev Biol
, vol.302
, Issue.1
, pp. 1-12
-
-
Zhang, B.1
Pan, X.2
Cobb, G.P.3
Anderson, T.A.4
-
78
-
-
46349087802
-
New hope for cancer treatment: Exploring the distinction between normal adult stem cells and cancer stem cells
-
Zhao RC, Zhu YS, Shi Y. New hope for cancer treatment: exploring the distinction between normal adult stem cells and cancer stem cells. Pharmacol Ther 2008; 119(1): 74-82.
-
(2008)
Pharmacol Ther
, vol.119
, Issue.1
, pp. 74-82
-
-
Zhao, R.C.1
Zhu, Y.S.2
Shi, Y.3
-
79
-
-
40749090479
-
Widespread deregulation of microRNA expression in human prostate cancer
-
Ozen M, Creighton CJ, Ozdemir M, Ittmann M. Widespread deregulation of microRNA expression in human prostate cancer. Oncogene 2008; 27(12): 1788-93.
-
(2008)
Oncogene
, vol.27
, Issue.12
, pp. 1788-1793
-
-
Ozen, M.1
Creighton, C.J.2
Ozdemir, M.3
Ittmann, M.4
-
80
-
-
74249084440
-
MiR-15a and miR-16-1 in cancer: Discovery, function and future perspectives
-
Aqeilan RI, Calin GA, Croce CM. miR-15a and miR-16-1 in cancer: discovery, function and future perspectives. Cell Death Differ 2008; 17(2): 215-20.
-
(2008)
Cell Death Differ
, vol.17
, Issue.2
, pp. 215-220
-
-
Aqeilan, R.I.1
Calin, G.A.2
Croce, C.M.3
-
81
-
-
69949087531
-
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells
-
Ji Q, Hao X, Zhang M, Tang W, Yang M, Li L, et al. MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLoS One 2009; 4(8): e6816.
-
(2009)
PLoS One
, vol.4
, Issue.8
-
-
Ji, Q.1
Hao, X.2
Zhang, M.3
Tang, W.4
Yang, M.5
Li, L.6
-
82
-
-
67649386118
-
Concepts in in vivo siRNA delivery for cancer therapy
-
Gondi CS, Rao JS. Concepts in in vivo siRNA delivery for cancer therapy. J Cell Physiol 2009; 220(2): 285-91.
-
(2009)
J Cell Physiol
, vol.220
, Issue.2
, pp. 285-291
-
-
Gondi, C.S.1
Rao, J.S.2
-
84
-
-
0035818885
-
Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening
-
Enyedy IJ, Ling Y, Nacro K, et al. Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening. J Med Chem 2001; 44(25): 4313-24.
-
(2001)
J Med Chem
, vol.44
, Issue.25
, pp. 4313-4324
-
-
Enyedy, I.J.1
Ling, Y.2
Nacro, K.3
-
85
-
-
0242721548
-
Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists
-
Wang S, Yang D, Lippman ME. Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists. Semin Oncol 2003; 30(5 Suppl 16): 133-42.
-
(2003)
Semin Oncol
, vol.30
, Issue.5 SUPPL. 16
, pp. 133-142
-
-
Wang, S.1
Yang, D.2
Lippman, M.E.3
-
86
-
-
0034691130
-
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
-
Wang JL, Liu D, Zhang ZJ, et al. Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. PNAS 2000; 97(13): 7124-9.
-
(2000)
PNAS
, vol.97
, Issue.13
, pp. 7124-7129
-
-
Wang, J.L.1
Liu, D.2
Zhang, Z.J.3
-
87
-
-
0034811108
-
Underphosphorylated BAD interacts with diverse antiapoptotic Bcl-2 family proteins to regulate apoptosis
-
Bae J, Hsu SY, Leo CP, Zell K, Hsueh AJ. Underphosphorylated BAD interacts with diverse antiapoptotic Bcl-2 family proteins to regulate apoptosis. Apoptosis 2001; 6(5): 319-30.
-
(2001)
Apoptosis
, vol.6
, Issue.5
, pp. 319-330
-
-
Bae, J.1
Hsu, S.Y.2
Leo, C.P.3
Zell, K.4
Hsueh, A.J.5
-
88
-
-
0033965412
-
Role of the BH3 (Bcl-2 homology 3) domain in the regulation of apoptosis and Bcl-2-related proteins
-
Lutz RJ. Role of the BH3 (Bcl-2 homology 3) domain in the regulation of apoptosis and Bcl-2-related proteins. Bioch Soc Trans 2000; 28(2): 51-6.
-
(2000)
Bioch Soc Trans
, vol.28
, Issue.2
, pp. 51-56
-
-
Lutz, R.J.1
-
89
-
-
0042528617
-
Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family
-
Shangary S, Johnson DE. Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family. Leukemia 2003; 17(8): 1470-81.
-
(2003)
Leukemia
, vol.17
, Issue.8
, pp. 1470-1481
-
-
Shangary, S.1
Johnson, D.E.2
-
90
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf T, Elmore SW, Shoemaker AR, et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 2005; 435(7042): 677-81.
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
-
91
-
-
33846674886
-
Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation
-
Chen S, Dai Y, Harada H, Dent P, Grant S. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation. Cancer Res 2007; 67(2): 782-91.
-
(2007)
Cancer Res
, vol.67
, Issue.2
, pp. 782-791
-
-
Chen, S.1
Dai, Y.2
Harada, H.3
Dent, P.4
Grant, S.5
-
92
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
Willis SN, Fletcher JI, Kaufmann T, et al. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 2007; 315(5813): 856-9.
-
(2007)
Science
, vol.315
, Issue.5813
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
-
93
-
-
33750834023
-
The BH3 mimetic ABT- 737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
-
van Delft MF, Wei AH, Mason KD, et al. The BH3 mimetic ABT- 737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. Cancer Cell 2006; 10(5): 389-99.
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 389-399
-
-
van Delft, M.F.1
Wei, A.H.2
Mason, K.D.3
-
94
-
-
34249996230
-
'Seed' analysis of off- target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737
-
Lin X, Morgan-Lappe S, Huang X, et al. 'Seed' analysis of off- target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737. Oncogene 2007; 26(27): 3972-9.
-
(2007)
Oncogene
, vol.26
, Issue.27
, pp. 3972-3979
-
-
Lin, X.1
Morgan-Lappe, S.2
Huang, X.3
-
95
-
-
33750628289
-
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
-
Konopleva M, Contractor R, Tsao T, et al. Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. Cancer Cell 2006; 10(5): 375-88.
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 375-388
-
-
Konopleva, M.1
Contractor, R.2
Tsao, T.3
-
96
-
-
67650786255
-
BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing
-
Martin AP, Park MA, Mitchell C, et al. BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing. Mol Pharmacol 2009; 76(2): 327-41.
-
(2009)
Mol Pharmacol
, vol.76
, Issue.2
, pp. 327-341
-
-
Martin, A.P.1
Park, M.A.2
Mitchell, C.3
-
97
-
-
65249099649
-
A novel Bcl-XL inhibitor Z36 that induces autophagic cell death in Hela cells
-
Lin J, Zheng Z, Li Y, et al. A novel Bcl-XL inhibitor Z36 that induces autophagic cell death in Hela cells. Autophagy 2009; 5(3): 314-20.
-
(2009)
Autophagy
, vol.5
, Issue.3
, pp. 314-320
-
-
Lin, J.1
Zheng, Z.2
Li, Y.3
-
98
-
-
56149092147
-
Regulation of antiapoptotic MCL-1 function by gossypol: Mechanistic insights from in vitro reconstituted systems
-
Etxebarria A, Landeta O, Antonsson B, Basanez G. Regulation of antiapoptotic MCL-1 function by gossypol: mechanistic insights from in vitro reconstituted systems. Biochem Pharmacol 2008; 76(11): 1563-76.
-
(2008)
Biochem Pharmacol
, vol.76
, Issue.11
, pp. 1563-1576
-
-
Etxebarria, A.1
Landeta, O.2
Antonsson, B.3
Basanez, G.4
-
99
-
-
0038682166
-
Molecular mechanism of gossypol- induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells
-
Zhang M, Liu H, Guo R, et al. Molecular mechanism of gossypol- induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells. Biochem Pharmacol 2003; 66(1): 93-103.
-
(2003)
Biochem Pharmacol
, vol.66
, Issue.1
, pp. 93-103
-
-
Zhang, M.1
Liu, H.2
Guo, R.3
-
100
-
-
0141569444
-
Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/ leukemia-2 proteins
-
Kitada S, Leone M, Sareth S, Zhai D, Reed JC, Pellecchia M. Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/ leukemia-2 proteins. J Med Chem 2003; 46(20): 4259-64.
-
(2003)
J Med Chem
, vol.46
, Issue.20
, pp. 4259-4264
-
-
Kitada, S.1
Leone, M.2
Sareth, S.3
Zhai, D.4
Reed, J.C.5
Pellecchia, M.6
-
101
-
-
0036244595
-
The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer
-
Liu S, Kulp SK, Sugimoto Y, et al. The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer. AntiCancer Res 2002; 22(1A): 33-8.
-
(2002)
AntiCancer Res
, vol.22
, Issue.1 A
, pp. 33-38
-
-
Liu, S.1
Kulp, S.K.2
Sugimoto, Y.3
-
102
-
-
9344226187
-
In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells
-
Oliver CL, Bauer JA, Wolter KG, et al. In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells. Clin Cancer Res 2004; 10(22): 7757-63.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.22
, pp. 7757-7763
-
-
Oliver, C.L.1
Bauer, J.A.2
Wolter, K.G.3
-
103
-
-
37149035009
-
In vivo evaluation of AT-101 (R-(-)-gossypol acetic acid) in androgen- independent growth of VCaP prostate cancer cells in combination with surgical castration
-
Loberg RD, McGregor N, Ying C, Sargent E, Pienta KJ. In vivo evaluation of AT-101 (R-(-)-gossypol acetic acid) in androgen- independent growth of VCaP prostate cancer cells in combination with surgical castration. Neoplasia 2007; 9(12): 1030-7.
-
(2007)
Neoplasia
, vol.9
, Issue.12
, pp. 1030-1037
-
-
Loberg, R.D.1
McGregor, N.2
Ying, C.3
Sargent, E.4
Pienta, K.J.5
-
104
-
-
51049106854
-
Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa
-
Meng Y, Tang W, Dai Y, et al. Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa. Mol Cancer Ther 2008; 7(7): 2192-202.
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.7
, pp. 2192-2202
-
-
Meng, Y.1
Tang, W.2
Dai, Y.3
-
105
-
-
20044368078
-
(-)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer
-
Xu L, Yang D, Wang S, et al. (-)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer. Mol Cancer Ther 2005; 4(2): 197-205.
-
(2005)
Mol Cancer Ther
, vol.4
, Issue.2
, pp. 197-205
-
-
Xu, L.1
Yang, D.2
Wang, S.3
-
106
-
-
52949131927
-
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
-
Kolluri SK, Zhu X, Zhou X, et al. A short Nur77-derived peptide converts Bcl-2 from a protector to a killer. Cancer Cell 2008; 14(4): 285-98.
-
(2008)
Cancer Cell
, vol.14
, Issue.4
, pp. 285-298
-
-
Kolluri, S.K.1
Zhu, X.2
Zhou, X.3
-
107
-
-
1342306819
-
Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
-
Lin B, Kolluri SK, Lin F, et al. Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 2004; 116(4): 527-40.
-
(2004)
Cell
, vol.116
, Issue.4
, pp. 527-540
-
-
Lin, B.1
Kolluri, S.K.2
Lin, F.3
-
108
-
-
45949094910
-
Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma
-
Paoluzzi L, Gonen M, Gardner JR, et al. Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma. Blood 2008; 111(11): 5350-8.
-
(2008)
Blood
, vol.111
, Issue.11
, pp. 5350-5358
-
-
Paoluzzi, L.1
Gonen, M.2
Gardner, J.R.3
-
109
-
-
70349694378
-
Combined Bcl- 2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non- small cell lung tumor xenograft model
-
Kim KW, Moretti L, Mitchell LR, Jung DK, Lu B. Combined Bcl- 2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non- small cell lung tumor xenograft model. Clin Cancer Res 2009; 15(19): 6096-105.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.19
, pp. 6096-6105
-
-
Kim, K.W.1
Moretti, L.2
Mitchell, L.R.3
Jung, D.K.4
Lu, B.5
-
110
-
-
63149129655
-
Bcl-2 inhibitors: Targeting mitochondrial apoptotic pathways in cancer therapy
-
Kang MH, Reynolds CP. Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy. Clin Cancer Res 2009; 15(4): 1126-32.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.4
, pp. 1126-1132
-
-
Kang, M.H.1
Reynolds, C.P.2
-
111
-
-
34447274052
-
Small molecule inhibition of the Bcl-X(L)-BH3 protein-protein interaction: Proof-of-concept of an in vivo chemopotentiator ABT-737
-
Stauffer SR. Small molecule inhibition of the Bcl-X(L)-BH3 protein-protein interaction: proof-of-concept of an in vivo chemopotentiator ABT-737. Curr Top Med Chem 2007; 7(10): 961-5.
-
(2007)
Curr Top Med Chem
, vol.7
, Issue.10
, pp. 961-965
-
-
Stauffer, S.R.1
-
112
-
-
67549141546
-
Different forms of cell death induced by putative BCL2 inhibitors
-
Vogler M, Weber K, Dinsdale D, et al. Different forms of cell death induced by putative BCL2 inhibitors. Cell Death Differ 2009; 16(7): 1030-9.
-
(2009)
Cell Death Differ
, vol.16
, Issue.7
, pp. 1030-1039
-
-
Vogler, M.1
Weber, K.2
Dinsdale, D.3
|