메뉴 건너뛰기




Volumn 112, Issue 7, 2011, Pages 1938-1948

Down-regulation of BMI-1 cooperates with artemisinin on growth inhibition of nasopharyngeal carcinoma cells

Author keywords

Artemisinin; BMI 1; Cell cycle arrest; Nasopharyngeal carcinoma

Indexed keywords

ARTEMISININ; BMI1 PROTEIN; CYCLIN DEPENDENT KINASE 4; PROTEIN P16;

EID: 80051506043     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23114     Document Type: Article
Times cited : (55)

References (47)
  • 1
    • 0029747162 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitors (CKIs) and hematological malignancies
    • Baghdassarian N, Ffrench M. 1996. Cyclin-dependent kinase inhibitors (CKIs) and hematological malignancies. Hematol Cell Ther 38:313-323. (Pubitemid 26292504)
    • (1996) Hematology and Cell Therapy , vol.38 , Issue.4 , pp. 313-323
    • Baghdassarian, N.1    Ffrench, M.2
  • 2
    • 0030467624 scopus 로고    scopus 로고
    • The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis
    • Bartkova J, Lukas J, Guldberg P, Alsner J, Kirkin AF, Zeuthen J, Bartek J. 1996. The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis. Cancer Res 56:5475-5483. (Pubitemid 27011383)
    • (1996) Cancer Research , vol.56 , Issue.23 , pp. 5475-5483
    • Bartkova, J.1    Lukas, J.2    Guldberg, P.3    Alsner, J.4    Kirkin, A.F.5    Zeuthen, J.6    Bartek, J.7
  • 3
    • 77951273802 scopus 로고    scopus 로고
    • Treatment approaches to nasopharyngeal carcinoma: A review
    • Caponigro F, Longo F, Ionna F, Perri F. 2010. Treatment approaches to nasopharyngeal carcinoma: A review. Anticancer Drugs 21:471-477.
    • (2010) Anticancer Drugs , vol.21 , pp. 471-477
    • Caponigro, F.1    Longo, F.2    Ionna, F.3    Perri, F.4
  • 4
  • 5
    • 1642619557 scopus 로고    scopus 로고
    • Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1
    • Chen HH, Zhou HJ, Wu GD, Lou XE. 2004. Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1. Pharmacology 71:1-9.
    • (2004) Pharmacology , vol.71 , pp. 1-9
    • Chen, H.H.1    Zhou, H.J.2    Wu, G.D.3    Lou, X.E.4
  • 6
    • 77951651771 scopus 로고    scopus 로고
    • Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: Involvement of cell cycle arrest and inactivation of nuclear factor-kappaB
    • Chen H, Sun B, Wang S, Pan S, Gao Y, Bai X, Xue D. 2010. Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: Involvement of cell cycle arrest and inactivation of nuclear factor-kappaB. J Cancer Res Clin Oncol 136:897-903.
    • (2010) J Cancer Res Clin Oncol , vol.136 , pp. 897-903
    • Chen, H.1    Sun, B.2    Wang, S.3    Pan, S.4    Gao, Y.5    Bai, X.6    Xue, D.7
  • 7
    • 65249121864 scopus 로고    scopus 로고
    • Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation
    • Dhawan S, Tschen SI, Bhushan A. 2009. Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation. Genes Dev 23:906-911.
    • (2009) Genes Dev , vol.23 , pp. 906-911
    • Dhawan, S.1    Tschen, S.I.2    Bhushan, A.3
  • 8
    • 0024315920 scopus 로고
    • Artemisinin (qinghaosu) - A new gametocytocidal drug for malaria
    • Dutta GP, Bajpai R, Vishwakarma RA. 1989. Artemisinin (qinghaosu)-A new gametocytocidal drug for malaria. Chemotherapy 35:200-207. (Pubitemid 19161234)
    • (1989) Chemotherapy , vol.35 , Issue.3 , pp. 200-207
    • Dutta, G.P.1    Bajpai, R.2    Vishwakarma, R.A.3
  • 9
    • 33646024956 scopus 로고    scopus 로고
    • Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells
    • DOI 10.2174/138945006776359412
    • Efferth T. 2006. Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells. Curr Drug Targets 7:407-421. (Pubitemid 43744832)
    • (2006) Current Drug Targets , vol.7 , Issue.4 , pp. 407-421
    • Efferth, T.1
  • 12
    • 0034721938 scopus 로고    scopus 로고
    • The Rb- CDK4/6 signaling pathway is critical in neural precursor cell cycle regulation
    • Ferguson KL, Callaghan SM, O'Hare MJ, Park DS, Slack RS. 2000. The Rb- CDK4/6 signaling pathway is critical in neural precursor cell cycle regulation. J Biol Chem 275:33593-33600.
    • (2000) J Biol Chem , vol.275 , pp. 33593-33600
    • Ferguson, K.L.1    Callaghan, S.M.2    O'Hare, M.J.3    Park, D.S.4    Slack, R.S.5
  • 13
    • 77952795743 scopus 로고    scopus 로고
    • Anticancer activities of artemisinin and its bioactive derivatives
    • Firestone GL, Sundar SN. 2009. Anticancer activities of artemisinin and its bioactive derivatives. Expert Rev Mol Med 11:e32.
    • (2009) Expert Rev Mol Med , vol.11
    • Firestone, G.L.1    Sundar, S.N.2
  • 15
    • 33846850149 scopus 로고    scopus 로고
    • Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins
    • DOI 10.1091/mbc.E06-05-0447
    • Guo WJ, Datta S, Band V, Dimri GP. 2007. Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins. Mol Biol Cell 18:536-546. (Pubitemid 46213222)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.2 , pp. 536-546
    • Guo, W.-J.1    Datta, S.2    Band, V.3    Dimri, G.P.4
  • 16
    • 0025727771 scopus 로고
    • Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice
    • Haupt Y, Alexander WS, Barri G, Klinken SP, Adams JM. 1991. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice. Cell 65:753-763. (Pubitemid 121001307)
    • (1991) Cell , vol.65 , Issue.5 , pp. 753-763
    • Haupt, Y.1    Alexander, W.S.2    Barri, G.3    Klinken, S.P.4    Adams, J.M.5
  • 17
    • 78751582382 scopus 로고    scopus 로고
    • The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1alpha in human rheumatoid arthritis fibroblast-like synoviocyte
    • He Y, Fan J, Lin H, Yang X, Ye Y, Liang L, Zhan Z, Dong X, Sun L, Xu H. 2009a. The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1alpha in human rheumatoid arthritis fibroblast-like synoviocyte. Rheumatol Int 31:53-60.
    • (2009) Rheumatol Int , vol.31 , pp. 53-60
    • He, Y.1    Fan, J.2    Lin, H.3    Yang, X.4    Ye, Y.5    Liang, L.6    Zhan, Z.7    Dong, X.8    Sun, L.9    Xu, H.10
  • 18
    • 63549087793 scopus 로고    scopus 로고
    • Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo
    • He S, Iwashita T, Buchstaller J, Molofsky AV, Thomas D, Morrison SJ. 2009b. Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo. Dev Biol 328:257-272.
    • (2009) Dev Biol , vol.328 , pp. 257-272
    • He, S.1    Iwashita, T.2    Buchstaller, J.3    Molofsky, A.V.4    Thomas, D.5    Morrison, S.J.6
  • 19
    • 0028918388 scopus 로고
    • Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
    • Hirai H, Roussel MF, Kato JY, Ashmun RA, Sherr CJ. 1995. Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol Cell Biol 15:2672-2681.
    • (1995) Mol Cell Biol , vol.15 , pp. 2672-2681
    • Hirai, H.1    Roussel, M.F.2    Kato, J.Y.3    Ashmun, R.A.4    Sherr, C.J.5
  • 20
    • 53049086416 scopus 로고    scopus 로고
    • Experimental therapy of hepatoma with artemisinin and its derivatives: In vitro and in vivo activity, chemosensitization, and mechanisms of action
    • Hou J, Wang D, Zhang R, Wang H. 2008. Experimental therapy of hepatoma with artemisinin and its derivatives: In vitro and in vivo activity, chemosensitization, and mechanisms of action. Clin Cancer Res 14:5519-5530.
    • (2008) Clin Cancer Res , vol.14 , pp. 5519-5530
    • Hou, J.1    Wang, D.2    Zhang, R.3    Wang, H.4
  • 21
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycombgroup gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • DOI 10.1038/16476
    • Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. 1999. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 97:164-168. (Pubitemid 29050921)
    • (1999) Nature , vol.397 , Issue.6715 , pp. 164-168
    • Jacobs, J.L.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    Van Lohuizen, M.5
  • 22
    • 0037427563 scopus 로고    scopus 로고
    • Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana
    • DOI 10.1016/S0304-3835(02)00497-4, PII S0304383502004974
    • Jayaprakasam B, Seeram NP, Nair MG. 2003. Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana. Cancer Lett 189: 11-16. (Pubitemid 35351514)
    • (2003) Cancer Letters , vol.189 , Issue.1 , pp. 11-16
    • Jayaprakasam, B.1    Seeram, N.P.2    Nair, M.G.3
  • 23
    • 67651011983 scopus 로고    scopus 로고
    • Induction of apoptosis by aqueous extract of Cordyceps militaris through activation of caspases and inactivation of Akt in human breast cancer MDA-MB-231 Cells
    • Jin CY, Kim GY, Choi YH. 2008. Induction of apoptosis by aqueous extract of Cordyceps militaris through activation of caspases and inactivation of Akt in human breast cancer MDA-MB-231 Cells. J Microbiol Biotechnol 18:1997-2003.
    • (2008) J Microbiol Biotechnol , vol.18 , pp. 1997-2003
    • Jin, C.Y.1    Kim, G.Y.2    Choi, Y.H.3
  • 24
    • 0021948029 scopus 로고
    • Qinghaosu (Artemisinin): An antimalarial drug from China
    • Klayman DL. 1985. Qinghaosu (artemisinin): An antimalarial drug from China. Science 228:1049-1055. (Pubitemid 15227365)
    • (1985) Science , vol.228 , Issue.4703 , pp. 1049-1055
    • Klayman, D.L.1
  • 25
    • 0036433743 scopus 로고    scopus 로고
    • Genetic and epigenetic changes in nasopharyngeal carcinoma
    • DOI 10.1016/S1044579X02000883
    • Lo KW, Huang DP. 2002. Genetic and epigenetic changes in nasopharyngeal carcinoma. Semin Cancer Biol 12:451-462. (Pubitemid 35370758)
    • (2002) Seminars in Cancer Biology , vol.12 , Issue.6 , pp. 451-462
    • Lo, K.-W.1    Huang, D.P.2
  • 26
    • 0023110445 scopus 로고
    • The chemistry, pharmacology, and clinical applications of qinghaosu (artemisinin) and its derivatives
    • Luo XD, Shen CC. 1987. The chemistry, pharmacology, and clinical applications of qinghaosu (artemisinin) and its derivatives. Med Res Rev 7:29-52.
    • (1987) Med Res Rev , vol.7 , pp. 29-52
    • Luo, X.D.1    Shen, C.C.2
  • 27
    • 0029811716 scopus 로고    scopus 로고
    • G1 cyclin/CDK-independent phosphorylation and accumulation of p13O during the transition from G1 to G0 lead to its association with E2F-4
    • Mayol X, Garriga J, Grana X. 1996. G1 cyclin/CDK-independent phosphorylation and accumulation of p130 during the transition from G1 to G0 lead to its association with E2F-4. Oncogene 13:237-246. (Pubitemid 26334855)
    • (1996) Oncogene , vol.13 , Issue.2 , pp. 237-246
    • Mayol, X.1    Garriga, J.2    Grana, X.3
  • 28
    • 77956896284 scopus 로고    scopus 로고
    • Growth inhibition and cell-cycle arrest of human gastric cancer cells by Lycium barbarum polysaccharide
    • Miao Y, Xiao B, Jiang Z, Guo Y, Mao F, Zhao J, Huang X, Guo J. 2009. Growth inhibition and cell-cycle arrest of human gastric cancer cells by Lycium barbarum polysaccharide. Med Oncol 27:785-790.
    • (2009) Med Oncol , vol.27 , pp. 785-790
    • Miao, Y.1    Xiao, B.2    Jiang, Z.3    Guo, Y.4    Mao, F.5    Zhao, J.6    Huang, X.7    Guo, J.8
  • 29
    • 22344449361 scopus 로고    scopus 로고
    • Arf senescence pathways
    • DOI 10.1101/gad.1299505
    • Molofsky AV, He S, Bydon M, Morrison SJ, Pardal R. 2005. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev 19:1432-1437. (Pubitemid 41003009)
    • (2005) Genes and Development , vol.19 , Issue.12 , pp. 1432-1437
    • Molofsky, A.V.1    He, S.2    Bydon, M.3    Morrison, S.J.4    Pardal, R.5
  • 33
    • 67650669265 scopus 로고    scopus 로고
    • Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression
    • Riganti C, Doublier S, Viarisio D, Miraglia E, Pescarmona G, Ghigo D, Bosia A. 2009. Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression. Br J Pharmacol 156:1054-1066.
    • (2009) Br J Pharmacol , vol.156 , pp. 1054-1066
    • Riganti, C.1    Doublier, S.2    Viarisio, D.3    Miraglia, E.4    Pescarmona, G.5    Ghigo, D.6    Bosia, A.7
  • 35
    • 33845745350 scopus 로고    scopus 로고
    • Implication of polycomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT, and c-Myc expression in primary breast carcinomas
    • DOI 10.1158/1078-0432.CCR-06-0788
    • Silva J, Garcia JM, Pena C, Garcia V, Dominguez G, Suarez D, Camacho FI, Espinosa R, Provencio M, Espana P, Bonilla F. 2006. Implication of polycomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT, and c-Myc expression in primary breast carcinomas. Clin Cancer Res 12:6929-6936. (Pubitemid 44974485)
    • (2006) Clinical Cancer Research , vol.12 , Issue.23 , pp. 6929-6936
    • Silva, J.1    Garcia, J.M.2    Pena, C.3    Garcia, V.4    Dominguez, G.5    Suarez, D.6    Camacho, F.I.7    Espinosa, R.8    Provencio, M.9    Espana, P.10    Bonilla, F.11
  • 36
    • 4444261942 scopus 로고    scopus 로고
    • Artemisinin induces apoptosis in human cancer cells
    • Singh NP, Lai HC. 2004. Artemisinin induces apoptosis in human cancer cells. Anticancer Res 24:2277-2280. (Pubitemid 39166306)
    • (2004) Anticancer Research , vol.24 , Issue.4 , pp. 2277-2280
    • Singh, N.P.1    Lai, H.C.2
  • 38
    • 38149125450 scopus 로고    scopus 로고
    • Leukemic stem cells: From metabolic pathways and signaling to a new concept of drug resistance targeting
    • Styczynski J, Drewa T. 2007. Leukemic stem cells: From metabolic pathways and signaling to a new concept of drug resistance targeting. Acta Biochim Pol 54:717-726.
    • (2007) Acta Biochim Pol , vol.54 , pp. 717-726
    • Styczynski, J.1    Drewa, T.2
  • 39
    • 34548631786 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma: Molecular pathogenesis and therapeutic developments
    • DOI 10.1017/S1462399407000312, PII S1462399407000312
    • Tao Q, Chan AT. 2007. Nasopharyngeal carcinoma: Molecular pathogenesis and therapeutic developments. Expert Rev Mol Med 9:1-24. (Pubitemid 47398642)
    • (2007) Expert Reviews in Molecular Medicine , vol.9 , Issue.12 , pp. 1-24
    • Tao, Q.1    Chan, A.T.C.2
  • 40
    • 0029860958 scopus 로고    scopus 로고
    • Detection of Epstein-Barr Virus DNA in well and poorly differentiated nasopharyngeal carcinoma cell lines
    • DOI 10.1007/BF00576978
    • Teng ZP, Ooka T, Huang DP, Zeng Y. 1996. Detection of Epstein-Barr virus DNA in well and poorly differentiated nasopharyngeal carcinoma cell lines. Virus Genes 13:53-60. (Pubitemid 26377625)
    • (1996) Virus Genes , vol.13 , Issue.1 , pp. 53-60
    • Teng, Z.-P.1    Ooka, T.2    Huang, D.P.3    Zeng, Y.4
  • 42
    • 59049096024 scopus 로고    scopus 로고
    • Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression
    • Willoughby JA, Sr., Sundar SN, Cheung M, Tin AS, Modiano J, Firestone GL. 2009. Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression. J Biol Chem 284:2203-2213.
    • (2009) J Biol Chem , vol.284 , pp. 2203-2213
    • Willoughby Sr., J.A.1    Sundar, S.N.2    Cheung, M.3    Tin, A.S.4    Modiano, J.5    Firestone, G.L.6
  • 43
    • 47349100951 scopus 로고    scopus 로고
    • Natural compounds with proteasome inhibitory activity for cancer prevention and treatment
    • DOI 10.2174/138920308784533998
    • Yang H, Landis-Piwowar KR, Chen D, Milacic V, Dou QP. 2008. Natural compounds with proteasome inhibitory activity for cancer prevention and treatment. Curr Protein Pept Sci 9:227-239. (Pubitemid 351997839)
    • (2008) Current Protein and Peptide Science , vol.9 , Issue.3 , pp. 227-239
    • Yang, H.1    Landis-Piwowar, K.R.2    Chen, D.3    Milacic, V.4    Dou, Q.P.5
  • 44
    • 34249906468 scopus 로고    scopus 로고
    • Molecular mechanism of anti-prostate cancer activity of Scutellaria Baicalensis extract
    • Ye F, Jiang S, Volshonok H, Wu J, Zhang DY. 2007. Molecular mechanism of anti-prostate cancer activity of Scutellaria baicalensis extract. Nutr Cancer 57:100-110. (Pubitemid 46871574)
    • (2007) Nutrition and Cancer , vol.57 , Issue.1 , pp. 100-110
    • Ye, F.1    Jiang, S.2    Volshonok, H.3    Wu, J.4    Zhang, D.Y.5
  • 46
    • 0042467687 scopus 로고    scopus 로고
    • Epstein-Barr virus and oncogenesis: From latent genes to tumours
    • DOI 10.1038/sj.onc.1206556
    • Young LS, Murray PG. 2003. Epstein-Barr virus and oncogenesis: From latent genes to tumours. Oncogene 22:5108-5121. (Pubitemid 37059592)
    • (2003) Oncogene , vol.22 , Issue.33 REV. ISS. 2 , pp. 5108-5121
    • Young, L.S.1    Murray, P.G.2
  • 47
    • 34548676362 scopus 로고    scopus 로고
    • The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities
    • DOI 10.1002/ijc.22883
    • Zhu JY, Lavrik IN, Mahlknecht U, Giaisi M, Proksch P, Krammer PH, Li-Weber M. 2007. The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities. Int J Cancer 121:1839-1846. (Pubitemid 47417305)
    • (2007) International Journal of Cancer , vol.121 , Issue.8 , pp. 1839-1846
    • Zhu, J.Y.1    Lavrik, I.N.2    Mahlknecht, U.3    Giaisi, M.4    Proksch, P.5    Krammer, P.H.6    Li-Weber, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.