In vitro neurotoxigity of artemisinin derivatives

Medecine Tropicale

Volumn 58, Issue 3 SUPPL. 1, 1998, Pages 28-31

  Mclean, W G ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Antimalarial; Artemisinin; Neurotoxicity; Qinghaosu; Toxicity

Indexed keywords

ANTIMALARIAL AGENT; ARTEETHER; ARTEMETHER; ARTEMISININ; ARTEMISININ DERIVATIVE; DIHYDROQUINGHAOSU; SESQUITERPENE;

ANIMAL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM DISEASE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; ELECTRON MICROSCOPY; METHODOLOGY; MOUSE; NERVE CELL; NEUROBLASTOMA; REPRODUCIBILITY;

ANIMALS; ANTIMALARIALS; ARTEMISININS; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM DISEASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; MICE; MICROSCOPY, ELECTRON; NEUROBLASTOMA; NEURONS; REPRODUCIBILITY OF RESULTS; SESQUITERPENES; TUMOR CELLS, CULTURED;

EID: 0032242275     PISSN: 0025682X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (2)

1. - BREWER T.G., GRATE S.J., PEGGINS J.O. et al. - Fatal neurotoxicity of arteether and artemether. Am. J. Trop. Med. Hyg. 1994 ; 51: 251-259.
2. - KAMCHONWONGPAISAN S., McKEEVER P., HOSSLER P. et al. -Artemisinin neurotoxicity : neuropathology in rats and mechanistic studies in vitro, Am. J. Trop. Med. Hyg. 1997 ; 56 : 7-12.