The metabolism of steroids, toxins and drugs by 11β-hydroxysteroid dehydrogenase 1

Toxicology

Volumn 292, Issue 1, 2012, Pages 1-12

  Zhou, Hong Yu ^a   Hu, Guo Xin ^a   Lian, Qing Quan ^a   Morris, David ^b   Ge, Ren Shan ^a,c  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b BROWN UNIVERSITY   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

11 Hydroxysteroid dehydrogenase; Carbonyl reduction; Glucocorticoid; Redox

Indexed keywords

11 KETOANDROSTENEDIONE; 11 OXOTESTOSTERONE; 11BETA HYDROXYANDROSTENEDIONE; 11BETA HYDROXYPROGESTERONE; 11BETA HYDROXYSTEROID DEHYDROGENASE 1; 11BETA HYDROXYTESTOSTERONE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; 4 NITROACETOPHENONE; 4 NITROBENZALDEHYDE; 7 ALPHA HYDROXYDEHYDROEPIANDROSTERONE; 7 BETA HYDROXYDEHYDROEPIANDROSTERONE; 7 KETO DEHYDROEPIANDROSTERONE; 7 OXOCHOLESTEROL; 7ALPHA HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; BENFLURON; CARBONYL DERIVATIVE; CORTICOSTERONE; EPIANDROSTERONE; HYDROCORTISONE; METYRAPONE; ORACIN; PRASTERONE SULFATE; PREGN 4 ENE 3,11,20 TRIONE; STEROID; TRIADIMEFON; UNCLASSIFIED DRUG;

CARCINOGENIC ACTIVITY; CATALYSIS; CELL METABOLISM; DRUG METABOLISM; DRUG POTENCY; ENZYME ACTIVITY; ENZYME STRUCTURE; HUMAN; LIVER METABOLISM; NONHUMAN; PRIORITY JOURNAL; REVIEW; STEROID METABOLISM; TERATOGENICITY;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; AMINO ACID SEQUENCE; ANIMALS; CORTISONE; DRUG TOXICITY; HUMANS; HYDROCORTISONE; MOLECULAR SEQUENCE DATA; PHARMACEUTICAL PREPARATIONS; STEROIDS;

EID: 84855298464     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.11.012     Document Type: Review

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