Hexose-6-phosphate dehydrogenase knock-out mice lack 11β- hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation

Journal of Biological Chemistry

Volumn 281, Issue 10, 2006, Pages 6546-6551

  Lavery, Gareth G ^a,b   Walker, Elizabeth A ^b   Draper, Nicole ^a,b   Jeyasuria, Pancharatnam ^a   Marcos, Josep ^c   Shackleton, Cedric H L ^c   Parker, Keith L ^a   White, Perrin C ^a   Stewart, Paul M ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; GENES; GLUCOSE; HORMONES; METABOLISM; REACTION KINETICS;

ENDOPLASMIC RETICULUM; GLUCOCORTICOID GENERATION; OXOREDUCTASE ACTIVITY; VISCERAL ADIPOSITY;

ENZYME KINETICS;

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTERONE; DEHYDROCORTICOSTERONE; GLUCOCORTICOID; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; GALACTOSE 6 PHOSPHATE DEHYDROGENASE; GALACTOSE-6-PHOSPHATE DEHYDROGENASE; OXIDOREDUCTASE;

ADRENAL FUNCTION; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; GENE DISRUPTION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ADRENAL GLAND; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; ENZYMOLOGY; FEMALE; GENE DELETION; GENETICS; KINETICS; LIVER MICROSOME; MALE; METABOLIC SYNDROME X; MOUSE MUTANT; PHYSIOLOGY;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ADRENAL GLANDS; ANIMALS; CARBOHYDRATE DEHYDROGENASES; FEMALE; GLUCOCORTICOIDS; KINETICS; MALE; METABOLIC SYNDROME X; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSOMES, LIVER; SEQUENCE DELETION;

EID: 33646007919     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M512635200     Document Type: Article

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