Novel enzymological profiles of human 11β-hydroxysteroid dehydrogenase type 1

Chemico-Biological Interactions

Volumn 130-132, Issue , 2001, Pages 805-814

  Hult, M ^a   Nobel, C S I ^b   Abrahmsen, L ^b   Nicoll Griffith, D A ^c   Jornvall H ^a   Oppermann, U C T ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Pharmacia Corporation   (Sweden)

^c MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

11 HSD; Carbonyl reduction; Lactol oxidation; Phase I metabolism; Short chain dehydrogenases reductases

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CARCINOGEN; HYDROXYL GROUP; INSECTICIDE; KETOPROFEN; LACTONE DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; XENOBIOTIC AGENT;

CATALYSIS; CONFERENCE PAPER; ENZYME ANALYSIS; ENZYME SPECIFICITY; HORMONE ACTION; HUMAN; NONHUMAN; OXIDATION REDUCTION REACTION; PICHIA PASTORIS; PROTEIN EXPRESSION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOOXYGENASE INHIBITORS; GENE EXPRESSION; HUMANS; HYDROXYSTEROID DEHYDROGENASES; KETOPROFEN; OXIDATION-REDUCTION; PICHIA; PRODRUGS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; XENOBIOTICS;

PICHIA PASTORIS;

EID: 0035969827     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(00)00236-2     Document Type: Conference Paper

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