메뉴 건너뛰기




Volumn 99, Issue 4-5, 2006, Pages 215-222

Inter-conversion of 7α- and 7β-hydroxy-dehydroepiandrosterone by the human 11β-hydroxysteroid dehydrogenase type 1

Author keywords

Anti glucocorticoid; Cortisol; Cortisone; Hydroxysteroid dehydrogenase; Steroid

Indexed keywords

11BETA HYRDOXYSTEROID DEHYDROGENASE TYPE 1; 7ALPHA HYDROXY DEHYDROEPIANDROSTERONE; 7BETA HYDROXY DEHYDROEPIANDROSTERONE; OXIDOREDUCTASE; PRASTERONE; UNCLASSIFIED DRUG; 11BETA HYDROXYSTEROID DEHYDROGENASE; CORTISONE; HYDROCORTISONE; PRIMER DNA;

EID: 33746232050     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2005.12.001     Document Type: Article
Times cited : (73)

References (38)
  • 1
    • 0032457353 scopus 로고    scopus 로고
    • Immunoassay of 7-hydroxysteroids: 1. Radioimmunoassay of 7 beta-hydroxydehydroepiandrosterone
    • Lapcik O., Hampl R., Hill M., Bicikova M., and Starka L. Immunoassay of 7-hydroxysteroids: 1. Radioimmunoassay of 7 beta-hydroxydehydroepiandrosterone. J. Steroid Biochem. Mol. Biol. 67 (1998) 439-445
    • (1998) J. Steroid Biochem. Mol. Biol. , vol.67 , pp. 439-445
    • Lapcik, O.1    Hampl, R.2    Hill, M.3    Bicikova, M.4    Starka, L.5
  • 2
    • 0342615015 scopus 로고    scopus 로고
    • Immunoassay of 7-hydroxysteroids: 2. Radioimmunoassay of 7 alpha-hydroxy-dehydroepiandrosterone
    • Lapcik O., Hampl R., Hill M., and Starka L. Immunoassay of 7-hydroxysteroids: 2. Radioimmunoassay of 7 alpha-hydroxy-dehydroepiandrosterone. J. Steroid Biochem. Mol. Biol. 71 (1999) 231-237
    • (1999) J. Steroid Biochem. Mol. Biol. , vol.71 , pp. 231-237
    • Lapcik, O.1    Hampl, R.2    Hill, M.3    Starka, L.4
  • 3
    • 0035940722 scopus 로고    scopus 로고
    • 7-Hydroxydehydroepiandrosterone epimers in human serum and saliva. Comparison of gas chromatography-mass spectrometry and radioimmunoassay
    • Hill M., Lapcik O., Havlikova H., Morfin R., and Hampl R. 7-Hydroxydehydroepiandrosterone epimers in human serum and saliva. Comparison of gas chromatography-mass spectrometry and radioimmunoassay. J. Chromatogr. A 935 (2001) 297-307
    • (2001) J. Chromatogr. A , vol.935 , pp. 297-307
    • Hill, M.1    Lapcik, O.2    Havlikova, H.3    Morfin, R.4    Hampl, R.5
  • 4
    • 0033386688 scopus 로고    scopus 로고
    • Structure and functions of human oxysterol 7 alpha-hydroxylase cDNAs and gene CYP7B1
    • Wu Z.L., Martin K.O., Javitt N.B., and Chiang J.Y.L. Structure and functions of human oxysterol 7 alpha-hydroxylase cDNAs and gene CYP7B1. J. Lipid Res. 40 (1999) 2195-2203
    • (1999) J. Lipid Res. , vol.40 , pp. 2195-2203
    • Wu, Z.L.1    Martin, K.O.2    Javitt, N.B.3    Chiang, J.Y.L.4
  • 5
    • 0347296102 scopus 로고    scopus 로고
    • In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients
    • Weill-Engerer S., David J.P., Sazdovitch V., Liere P., Schumacher M., Delacourte A., Baulieu E.E., and Akwa Y. In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients. Brain Res. 969 (2003) 117-125
    • (2003) Brain Res. , vol.969 , pp. 117-125
    • Weill-Engerer, S.1    David, J.P.2    Sazdovitch, V.3    Liere, P.4    Schumacher, M.5    Delacourte, A.6    Baulieu, E.E.7    Akwa, Y.8
  • 6
    • 0027360616 scopus 로고
    • Metabolism of dehydroepiandrosterrone by human adipose stromal cells. Identification of 7α-hydroxy-dehydroepiandrosterone as a major metabolite using high performance liquid chromatography and mass spectrometry
    • Khalil M.W., Strutt B., Vachon D., and Killinger D.W. Metabolism of dehydroepiandrosterrone by human adipose stromal cells. Identification of 7α-hydroxy-dehydroepiandrosterone as a major metabolite using high performance liquid chromatography and mass spectrometry. J. Steroid Biochem. Mol. Biol. 46 (1993) 585-595
    • (1993) J. Steroid Biochem. Mol. Biol. , vol.46 , pp. 585-595
    • Khalil, M.W.1    Strutt, B.2    Vachon, D.3    Killinger, D.W.4
  • 9
    • 0036887723 scopus 로고    scopus 로고
    • Steroid and sterol 7-hydroxylation: ancient pathways
    • Lathe R. Steroid and sterol 7-hydroxylation: ancient pathways. Steroids 67 (2002) 967-977
    • (2002) Steroids , vol.67 , pp. 967-977
    • Lathe, R.1
  • 10
    • 0037445848 scopus 로고    scopus 로고
    • Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11beta-hydroxysteroid dehydrogenases?
    • Robinzon B., Michael K.K., Ripp S.L., Winters S.J., and Prough R.A. Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11beta-hydroxysteroid dehydrogenases?. Arch. Biochem. Biophys. 412 (2003) 251-258
    • (2003) Arch. Biochem. Biophys. , vol.412 , pp. 251-258
    • Robinzon, B.1    Michael, K.K.2    Ripp, S.L.3    Winters, S.J.4    Prough, R.A.5
  • 11
    • 85047683614 scopus 로고    scopus 로고
    • Minireview: 11beta-hydroxysteroid dehydrogenase type 1-a tissue-specific amplifier of glucocorticoid action
    • Seckl J.R., and Walker B.R. Minireview: 11beta-hydroxysteroid dehydrogenase type 1-a tissue-specific amplifier of glucocorticoid action. Endocrinology 142 (2001) 1371-1376
    • (2001) Endocrinology , vol.142 , pp. 1371-1376
    • Seckl, J.R.1    Walker, B.R.2
  • 12
    • 0036889680 scopus 로고    scopus 로고
    • Use of bioconversion for the preparation of [4-14C]-labeled 7alpha- and 7beta-hydroxylated derivatives of dehydroepiandrosterone and epiandrosterone
    • Chalbot S., Trap C., Monin J.P., and Morfin R. Use of bioconversion for the preparation of [4-14C]-labeled 7alpha- and 7beta-hydroxylated derivatives of dehydroepiandrosterone and epiandrosterone. Steroids 67 (2002) 1121-1127
    • (2002) Steroids , vol.67 , pp. 1121-1127
    • Chalbot, S.1    Trap, C.2    Monin, J.P.3    Morfin, R.4
  • 13
    • 0026095840 scopus 로고
    • The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization
    • Tannin G.M., Agarwal A.K., Monder C., New M.I., and White P.C. The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization. J. Biol. Chem. 266 (1991) 16653-16658
    • (1991) J. Biol. Chem. , vol.266 , pp. 16653-16658
    • Tannin, G.M.1    Agarwal, A.K.2    Monder, C.3    New, M.I.4    White, P.C.5
  • 14
    • 13244290114 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and its 7-hydroxylated metabolites do not interfere with the transactivation and cellular trafficking of the glucocorticoid receptor
    • Muller C., Cluzeaud F., Pinon G., Rafestin-Oblin M., and Morfin R. Dehydroepiandrosterone and its 7-hydroxylated metabolites do not interfere with the transactivation and cellular trafficking of the glucocorticoid receptor. J. Steroid Biochem. Mol. Biol. 92 (2004) 469-476
    • (2004) J. Steroid Biochem. Mol. Biol. , vol.92 , pp. 469-476
    • Muller, C.1    Cluzeaud, F.2    Pinon, G.3    Rafestin-Oblin, M.4    Morfin, R.5
  • 15
    • 0029776005 scopus 로고    scopus 로고
    • Yeast expression of animal and plant P450s in optimized redox environments
    • Pompon D., Louerat B., Bronine A., and Urban P. Yeast expression of animal and plant P450s in optimized redox environments. Methods Enzymol. 272 (1996) 51-64
    • (1996) Methods Enzymol. , vol.272 , pp. 51-64
    • Pompon, D.1    Louerat, B.2    Bronine, A.3    Urban, P.4
  • 16
    • 0026562884 scopus 로고
    • Improved method for high efficiency transformation of intact yeast cells
    • Gietz D., StJean A., Woods R., and Schiestl R. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20 (1992) 1425
    • (1992) Nucleic Acids Res. , vol.20 , pp. 1425
    • Gietz, D.1    StJean, A.2    Woods, R.3    Schiestl, R.4
  • 17
    • 0027742081 scopus 로고
    • Xenobiotic metabolism in humanized yeast: engineered yeast cells producing human NADPH-cytochrome P-450 reductase, cytochrome b5, epoxide hydrolase and P-450s
    • Urban P., Truan G., Gautier J.C., and Pompon D. Xenobiotic metabolism in humanized yeast: engineered yeast cells producing human NADPH-cytochrome P-450 reductase, cytochrome b5, epoxide hydrolase and P-450s. Biochem. Soc. Trans. 21 (1993) 1028-1034
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 1028-1034
    • Urban, P.1    Truan, G.2    Gautier, J.C.3    Pompon, D.4
  • 19
    • 73049133557 scopus 로고
    • The measurement of pyridine nucleotides by enzymatic cycling
    • Lowry O.H., Passonneau J.V., Schulz D.W., and Rock M.K. The measurement of pyridine nucleotides by enzymatic cycling. J. Biol. Chem. 236 (1961) 2746-2755
    • (1961) J. Biol. Chem. , vol.236 , pp. 2746-2755
    • Lowry, O.H.1    Passonneau, J.V.2    Schulz, D.W.3    Rock, M.K.4
  • 20
    • 0015698911 scopus 로고
    • Quantitative estimation of unconjugated cortisol, cortisone, corticosterone, cortexone and cortexolone by thin-layer chromatography (author's translation)
    • Hartmann F., and Illner W.R. Quantitative estimation of unconjugated cortisol, cortisone, corticosterone, cortexone and cortexolone by thin-layer chromatography (author's translation). Res. Exp. Med. (Berl) 161 (1973) 165-174
    • (1973) Res. Exp. Med. (Berl) , vol.161 , pp. 165-174
    • Hartmann, F.1    Illner, W.R.2
  • 21
    • 0345004847 scopus 로고    scopus 로고
    • Selective inhibition of human type 1 11beta-hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics
    • Hult M., Jornvall H., and Oppermann U.C. Selective inhibition of human type 1 11beta-hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics. FEBS Lett. 441 (1998) 25-28
    • (1998) FEBS Lett. , vol.441 , pp. 25-28
    • Hult, M.1    Jornvall, H.2    Oppermann, U.C.3
  • 22
    • 0034599177 scopus 로고    scopus 로고
    • Human 11beta-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli
    • Blum A., Martin H.J., and Maser E. Human 11beta-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli. Toxicology 144 (2000) 113-120
    • (2000) Toxicology , vol.144 , pp. 113-120
    • Blum, A.1    Martin, H.J.2    Maser, E.3
  • 23
    • 4444339757 scopus 로고    scopus 로고
    • Biosynthesis of [3H]7 alpha-hydroxy-, 7 beta-hydroxy-, and 7-oxo-dehydroepiandrosterone using pig liver microsomal fractions
    • Robinzon B., Miller K.K., and Prough R.A. Biosynthesis of [3H]7 alpha-hydroxy-, 7 beta-hydroxy-, and 7-oxo-dehydroepiandrosterone using pig liver microsomal fractions. Anal. Biochem. 333 (2004) 128-135
    • (2004) Anal. Biochem. , vol.333 , pp. 128-135
    • Robinzon, B.1    Miller, K.K.2    Prough, R.A.3
  • 24
    • 2442614716 scopus 로고    scopus 로고
    • Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism
    • Hult M., Elleby B., Shafqat N., Svensson S., Rane A., Jornvall H., Abrahmsen L., and Oppermann U. Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism. Cell Mol. Life Sci. 61 (2004) 992-999
    • (2004) Cell Mol. Life Sci. , vol.61 , pp. 992-999
    • Hult, M.1    Elleby, B.2    Shafqat, N.3    Svensson, S.4    Rane, A.5    Jornvall, H.6    Abrahmsen, L.7    Oppermann, U.8
  • 25
    • 2442513350 scopus 로고    scopus 로고
    • Rapid hepatic metabolism of 7-ketocholesterol by 11beta -hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human and hamster enzyme
    • Schweizer R.A., Zurcher M., Balazs Z., Dick B., and Odermatt A. Rapid hepatic metabolism of 7-ketocholesterol by 11beta -hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human and hamster enzyme. J. Biol. Chem. 279 (2004) 18415-18424
    • (2004) J. Biol. Chem. , vol.279 , pp. 18415-18424
    • Schweizer, R.A.1    Zurcher, M.2    Balazs, Z.3    Dick, B.4    Odermatt, A.5
  • 27
    • 14944348745 scopus 로고    scopus 로고
    • CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines
    • Dulos J., van der Vleuten M.A., Kavelaars A., Heijnen C.J., and Boots A.M. CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines. Arthritis Rheum. 52 (2005) 770-778
    • (2005) Arthritis Rheum. , vol.52 , pp. 770-778
    • Dulos, J.1    van der Vleuten, M.A.2    Kavelaars, A.3    Heijnen, C.J.4    Boots, A.M.5
  • 28
    • 20444436794 scopus 로고    scopus 로고
    • Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: the Hertfordshire Cohort Study
    • Cooper M.S., Syddall H.E., Fall C.H., Wood P.J., Stewart P.M., Cooper C., and Dennison E.M. Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: the Hertfordshire Cohort Study. Clin. Endocrinol. (Oxf) 62 (2005) 692-697
    • (2005) Clin. Endocrinol. (Oxf) , vol.62 , pp. 692-697
    • Cooper, M.S.1    Syddall, H.E.2    Fall, C.H.3    Wood, P.J.4    Stewart, P.M.5    Cooper, C.6    Dennison, E.M.7
  • 29
    • 3342998410 scopus 로고    scopus 로고
    • Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase
    • Atanasov A.G., Nashev L.G., Schweizer R.A., Frick C., and Odermatt A. Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase. FEBS Lett. 571 (2004) 129-133
    • (2004) FEBS Lett. , vol.571 , pp. 129-133
    • Atanasov, A.G.1    Nashev, L.G.2    Schweizer, R.A.3    Frick, C.4    Odermatt, A.5
  • 30
    • 3042595899 scopus 로고    scopus 로고
    • Cooperativity between 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the lumen of the endoplasmic reticulum
    • Banhegyi G., Benedetti A., Fulceri R., and Senesi S. Cooperativity between 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the lumen of the endoplasmic reticulum. J. Biol. Chem. 279 (2004) 27017-27021
    • (2004) J. Biol. Chem. , vol.279 , pp. 27017-27021
    • Banhegyi, G.1    Benedetti, A.2    Fulceri, R.3    Senesi, S.4
  • 32
    • 0035081764 scopus 로고    scopus 로고
    • Effects of transdermal application of 7-oxo-DHEA on the levels of steroid hormones, gonadotropins and lipids in healthy men
    • Sulcova J., Hill M., Masek Z., Ceska R., Novacek A., Hampl R., and Starka L. Effects of transdermal application of 7-oxo-DHEA on the levels of steroid hormones, gonadotropins and lipids in healthy men. Physiol. Res. 50 (2001) 9-18
    • (2001) Physiol. Res. , vol.50 , pp. 9-18
    • Sulcova, J.1    Hill, M.2    Masek, Z.3    Ceska, R.4    Novacek, A.5    Hampl, R.6    Starka, L.7
  • 33
    • 0035225988 scopus 로고    scopus 로고
    • Neurosteroid 7-hydroxylation products in the brain
    • Morfin R., and Starka L. Neurosteroid 7-hydroxylation products in the brain. Int. Rev. Neurobiol. 46 (2001) 79-95
    • (2001) Int. Rev. Neurobiol. , vol.46 , pp. 79-95
    • Morfin, R.1    Starka, L.2
  • 34
    • 5644276386 scopus 로고    scopus 로고
    • Severity of murine collagen-induced arthritis correlates with increased CYP7B activity: enhancement of dehydroepiandrosterone metabolism by interleukin-1beta
    • Dulos J., Verbraak E., Bagchus W.M., Boots A.M., and Kaptein A. Severity of murine collagen-induced arthritis correlates with increased CYP7B activity: enhancement of dehydroepiandrosterone metabolism by interleukin-1beta. Arthritis Rheum. 50 (2004) 3346-3353
    • (2004) Arthritis Rheum. , vol.50 , pp. 3346-3353
    • Dulos, J.1    Verbraak, E.2    Bagchus, W.M.3    Boots, A.M.4    Kaptein, A.5
  • 35
    • 0032569018 scopus 로고    scopus 로고
    • Purification and characterization of hamster liver microsomal 7alpha-hydroxycholesterol dehydrogenase. Similarity to type I 11beta-hydroxysteroid dehydrogenase
    • Song W., Chen J., Dean W.L., Redinger R.N., and Prough R.A. Purification and characterization of hamster liver microsomal 7alpha-hydroxycholesterol dehydrogenase. Similarity to type I 11beta-hydroxysteroid dehydrogenase. J. Biol. Chem. 273 (1998) 16223-16228
    • (1998) J. Biol. Chem. , vol.273 , pp. 16223-16228
    • Song, W.1    Chen, J.2    Dean, W.L.3    Redinger, R.N.4    Prough, R.A.5
  • 36
    • 0036217056 scopus 로고    scopus 로고
    • Involvement of steroids and cytochromes P(450) species in the triggering of immune defenses
    • Morfin R. Involvement of steroids and cytochromes P(450) species in the triggering of immune defenses. J. Steroid Biochem. Mol. Biol. 80 (2002) 273-290
    • (2002) J. Steroid Biochem. Mol. Biol. , vol.80 , pp. 273-290
    • Morfin, R.1
  • 37
    • 1542270758 scopus 로고    scopus 로고
    • Protection against inflammatory neurodegeneration and glial cell death by 7beta-hydroxy epiandrosterone, a novel neurosteroid
    • Dudas B., Hanin I., Rose M., and Wulfert E. Protection against inflammatory neurodegeneration and glial cell death by 7beta-hydroxy epiandrosterone, a novel neurosteroid. Neurobiol. Dis. 15 (2004) 262-268
    • (2004) Neurobiol. Dis. , vol.15 , pp. 262-268
    • Dudas, B.1    Hanin, I.2    Rose, M.3    Wulfert, E.4
  • 38
    • 0042668350 scopus 로고    scopus 로고
    • 7-Hydroxylated epiandrosterone (7-OH-EPIA) reduces ischemia-induced neuronal damage both in vivo and in vitro
    • Pringle A., Schmidt W., Deans J., Wulfert E., Reymann K., and Sundstrom L. 7-Hydroxylated epiandrosterone (7-OH-EPIA) reduces ischemia-induced neuronal damage both in vivo and in vitro. Eur. J. Neurosci. 18 (2003) 117-124
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 117-124
    • Pringle, A.1    Schmidt, W.2    Deans, J.3    Wulfert, E.4    Reymann, K.5    Sundstrom, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.