메뉴 건너뛰기




Volumn 35, Issue 1, 2005, Pages 89-101

Comparative enzymology of 11β-hydroxysteroid dehydrogenase type 1 from six species

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; 7 OXOCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; ABIETIC ACID; CARBENOXOLONE; CHENODEOXYCHOLIC ACID; CORTISONE; DEHYDROCORTICOSTERONE; ENZYME INHIBITOR; FLAVANONE; FLAVANONE DERIVATIVE; GLYCYRRHETINIC ACID; HYDROCORTISONE; 11-DEHYDROCORTICOSTERONE; COMPLEMENTARY DNA; CORTICOSTERONE; DRUG DERIVATIVE; RECOMBINANT PROTEIN;

EID: 23844467917     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.1.01736     Document Type: Article
Times cited : (74)

References (47)
  • 1
  • 4
    • 3342998410 scopus 로고    scopus 로고
    • Hexose-6-phosphate dehydrogenase determines the reaction direction of 11 beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase
    • Atanasov AG, Nashev LG, Schweizer RA, Frick C & Odermatt A 2004 Hexose-6-phosphate dehydrogenase determines the reaction direction of 11 beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase. FEBS Letters 571 129-133.
    • (2004) FEBS Letters , vol.571 , pp. 129-133
    • Atanasov, A.G.1    Nashev, L.G.2    Schweizer, R.A.3    Frick, C.4    Odermatt, A.5
  • 5
    • 0037194658 scopus 로고    scopus 로고
    • Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11 beta-hydroxysteroid dehydrogenase type 1
    • Barf T, Vallgarda J, Emond R, Haggstrom C, Kurz G, Nygren A, Larwood V, Mosialou E, Axelsson K, Olsson R et al. 2002 Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11 beta-hydroxysteroid dehydrogenase type 1. Journal of Medicinal Chemistry 45 3813-3815.
    • (2002) Journal of Medicinal Chemistry , vol.45 , pp. 3813-3815
    • Barf, T.1    Vallgarda, J.2    Emond, R.3    Haggstrom, C.4    Kurz, G.5    Nygren, A.6    Larwood, V.7    Mosialou, E.8    Axelsson, K.9    Olsson, R.10
  • 6
    • 0031862891 scopus 로고    scopus 로고
    • Anti-inflammatory actions of glucocorticoids: Molecular mechanisms
    • Barnes PJ 1998 Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clinical Science (London) 94 557-572.
    • (1998) Clinical Science (London) , vol.94 , pp. 557-572
    • Barnes, P.J.1
  • 8
    • 0034623160 scopus 로고    scopus 로고
    • Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture
    • Brown AJ, Watts GF, Burnett JR, Dean RT & Jessup W 2000 Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture. Journal of Biological Chemistry 275 27627-27633.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 27627-27633
    • Brown, A.J.1    Watts, G.F.2    Burnett, J.R.3    Dean, R.T.4    Jessup, W.5
  • 10
    • 2342458276 scopus 로고    scopus 로고
    • Is 11 beta-hydroxysteroid dehydrogenase type 1 a good therapeutic target for blockade of glucocorticoid actions?
    • Chrousos GP 2004 Is 11 beta-hydroxysteroid dehydrogenase type 1 a good therapeutic target for blockade of glucocorticoid actions? PNAS 101 6329-6330.
    • (2004) PNAS , vol.101 , pp. 6329-6330
    • Chrousos, G.P.1
  • 11
    • 0017080253 scopus 로고
    • Plasma and adrenal cortisol concentrations in foetal, newborn and mother guinea-pigs during the perinatal period
    • Dalle M & Delost P 1976 Plasma and adrenal cortisol concentrations in foetal, newborn and mother guinea-pigs during the perinatal period. Journal of Endocrinology 70 207-214.
    • (1976) Journal of Endocrinology , vol.70 , pp. 207-214
    • Dalle, M.1    Delost, P.2
  • 12
    • 0041324898 scopus 로고    scopus 로고
    • The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: Molecular mechanisms for gene repression
    • De Bosscher K, Vanden Berghe W & Haegeman G 2003 The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression. Endocrine Reviews 24 488-522.
    • (2003) Endocrine Reviews , vol.24 , pp. 488-522
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3
  • 13
    • 0034056308 scopus 로고    scopus 로고
    • In the search for specific inhibitors of human 11 beta-hydroxysteroid-dehydrogenases (11 beta-HSDs), chenodeoxycholic acid selectively inhibits 11 beta-HSD-I
    • Diederich S, Grossmann C, Hanke B, Quinkler M, Herrmann M, Bahr V & Oelkers W 2000 In the search for specific inhibitors of human 11 beta-hydroxysteroid-dehydrogenases (11 beta-HSDs), chenodeoxycholic acid selectively inhibits 11 beta-HSD-I. European Journal of Endocrinology 142 200-207.
    • (2000) European Journal of Endocrinology , vol.142 , pp. 200-207
    • Diederich, S.1    Grossmann, C.2    Hanke, B.3    Quinkler, M.4    Herrmann, M.5    Bahr, V.6    Oelkers, W.7
  • 14
  • 17
    • 4544260173 scopus 로고    scopus 로고
    • Overexpression of 11β-hydroxysteroid dehydrogenase-1 in adipose tissue Is associated with acquired obesity and features of insulin resistance: Studies in young adult monozygotic twins
    • Kannisto K, Pietilainen KH, Ehrenborg E, Rissanen A, Kaprio J, Hamsten A & Yki-Jarvinen H 2004 Overexpression of 11β-hydroxysteroid dehydrogenase-1 in adipose tissue Is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins. Journal of Clinical Endocrinology and Metabolism 89 4414-4421.
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , pp. 4414-4421
    • Kannisto, K.1    Pietilainen, K.H.2    Ehrenborg, E.3    Rissanen, A.4    Kaprio, J.5    Hamsten, A.6    Yki-Jarvinen, H.7
  • 18
    • 0031761992 scopus 로고    scopus 로고
    • Structural determinants of cortisol resistance in the guinea pig glucocorticoid receptor
    • Keightley MC, Curtis AJ, Chu S & Fuller PJ 1998 Structural determinants of cortisol resistance in the guinea pig glucocorticoid receptor. Endocrinology 139 2479-2485.
    • (1998) Endocrinology , vol.139 , pp. 2479-2485
    • Keightley, M.C.1    Curtis, A.J.2    Chu, S.3    Fuller, P.J.4
  • 19
    • 0031283178 scopus 로고    scopus 로고
    • 11 beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress
    • Kotelevtsev Y, Holmes MC, Burchell A, Houston PM, Schmoll D, Jamieson P, Best R, Brown R, Edwards CR, Seckl JR et al. 1997 11 beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress. PNAS 94 14924-14929.
    • (1997) PNAS , vol.94 , pp. 14924-14929
    • Kotelevtsev, Y.1    Holmes, M.C.2    Burchell, A.3    Houston, P.M.4    Schmoll, D.5    Jamieson, P.6    Best, R.7    Brown, R.8    Edwards, C.R.9    Seckl, J.R.10
  • 20
    • 0037902924 scopus 로고    scopus 로고
    • Subcutaneous adipose 11 beta-hydroxysteroid dehydrogenase type 1 activity and messenger ribonucleic acid levels are associated with adiposity and insulinemia in Pima Indians and Caucasians
    • Lindsay RS, Wake DJ, Nair S, Bunt J, Livingstone DE, Permana PA, Tataranni PA & Walker BR 2003 Subcutaneous adipose 11 beta-hydroxysteroid dehydrogenase type 1 activity and messenger ribonucleic acid levels are associated with adiposity and insulinemia in Pima Indians and Caucasians. Journal of Clinical Endocrinology and Metabolism 88 2738-2744.
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , pp. 2738-2744
    • Lindsay, R.S.1    Wake, D.J.2    Nair, S.3    Bunt, J.4    Livingstone, D.E.5    Permana, P.A.6    Tataranni, P.A.7    Walker, B.R.8
  • 23
    • 1542675142 scopus 로고    scopus 로고
    • Tissue-specific glucocorticoid reactivating enzyme, 11 betahydroxysteroid dehydrogenase type 1 (11 beta-HSD1) - A promising drug target for the treatment of metabolic syndrome
    • Masuzaki H & Flier JS 2003 Tissue-specific glucocorticoid reactivating enzyme, 11 betahydroxysteroid dehydrogenase type 1 (11 beta-HSD1) - a promising drug target for the treatment of metabolic syndrome. Current Drug Targets. Immune, Endocrine and Metabolic Disorders 3 255-262.
    • (2003) Current Drug Targets. Immune, Endocrine and Metabolic Disorders , vol.3 , pp. 255-262
    • Masuzaki, H.1    Flier, J.S.2
  • 26
    • 3042774548 scopus 로고    scopus 로고
    • Effect of chenodeoxycholic acid on 11 beta-hydroxysteroid dehydrogenase in various target tissues
    • Morris DJ, Souness GW, Latif SA, Hardy MP & Brem AS 2004 Effect of chenodeoxycholic acid on 11 beta-hydroxysteroid dehydrogenase in various target tissues. Metabolism 53 811-816.
    • (2004) Metabolism , vol.53 , pp. 811-816
    • Morris, D.J.1    Souness, G.W.2    Latif, S.A.3    Hardy, M.P.4    Brem, A.S.5
  • 28
    • 0033214482 scopus 로고    scopus 로고
    • The N-terminal anchor sequences of 11 beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane
    • Odermatt A, Arnold P, Stauffer A, Frey BM & Frey FJ 1999 The N-terminal anchor sequences of 11 beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane. Journal of Biological Chemistry 274 28762-28770.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 28762-28770
    • Odermatt, A.1    Arnold, P.2    Stauffer, A.3    Frey, B.M.4    Frey, F.J.5
  • 30
    • 0028872766 scopus 로고
    • Cloning and primary structure of murine 11 betahydroxysteroid dehydrogenase/microsomal carbonyl reductase
    • Oppermann UC, Netter KJ & Maser E 1995 Cloning and primary structure of murine 11 betahydroxysteroid dehydrogenase/microsomal carbonyl reductase. European Journal of Biochemistry 227 202-208.
    • (1995) European Journal of Biochemistry , vol.227 , pp. 202-208
    • Oppermann, U.C.1    Netter, K.J.2    Maser, E.3
  • 31
    • 0021925486 scopus 로고
    • Plasma cortisol and corticosterone concentrations in the golden hamster (Mesocricetus auratus)
    • Ottenweller JE, Tapp WN, Burke JM & Natelson BH 1985 Plasma cortisol and corticosterone concentrations in the golden hamster (Mesocricetus auratus). Life Sciences 37 1551-1558.
    • (1985) Life Sciences , vol.37 , pp. 1551-1558
    • Ottenweller, J.E.1    Tapp, W.N.2    Burke, J.M.3    Natelson, B.H.4
  • 32
    • 2342510149 scopus 로고    scopus 로고
    • Metabolic syndrome without obesity: Hepatic overexpression of 11 beta-hydroxysteroid dehydrogenase type 1 in transgenic mice
    • Paterson JM, Morton NM, Fievet C, Kenyon CJ, Holmes MC, Staels B, Seckl JR & Mullins JJ 2004 Metabolic syndrome without obesity: hepatic overexpression of 11 beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. PNAS 101 7088-7093.
    • (2004) PNAS , vol.101 , pp. 7088-7093
    • Paterson, J.M.1    Morton, N.M.2    Fievet, C.3    Kenyon, C.J.4    Holmes, M.C.5    Staels, B.6    Seckl, J.R.7    Mullins, J.J.8
  • 33
    • 0036075081 scopus 로고    scopus 로고
    • Expression of the mRNA coding for 11 beta-hydroxysteroid dehydrogenase type 1 in adipose tissue from obese patients: An in situ hybridization study
    • Paulmyer-Lacroix O, Boullu S, Oliver C, Alessi MC & Grino M 2002 Expression of the mRNA coding for 11 beta-hydroxysteroid dehydrogenase type 1 in adipose tissue from obese patients: an in situ hybridization study. Journal of Clinical Endocrinology and Metabolism 87 2701-2705.
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , pp. 2701-2705
    • Paulmyer-Lacroix, O.1    Boullu, S.2    Oliver, C.3    Alessi, M.C.4    Grino, M.5
  • 34
    • 0033621776 scopus 로고    scopus 로고
    • Guinea pig 11 beta-hydroxysteroid dehydrogenase type 1: Primary structure and catalytic properties
    • Pu X & Yang K 2000 Guinea pig 11 beta-hydroxysteroid dehydrogenase type 1: primary structure and catalytic properties. Steroids 65 148-156.
    • (2000) Steroids , vol.65 , pp. 148-156
    • Pu, X.1    Yang, K.2
  • 39
    • 0035656177 scopus 로고    scopus 로고
    • Pathophysiology of modulation of local glucocorticoid levels by 11 beta-hydroxysteroid dehydrogenases
    • Sandeep TC & Walker BR 2001 Pathophysiology of modulation of local glucocorticoid levels by 11 beta-hydroxysteroid dehydrogenases. Trends in Endocrinology and Metabolism 12 446-453.
    • (2001) Trends in Endocrinology and Metabolism , vol.12 , pp. 446-453
    • Sandeep, T.C.1    Walker, B.R.2
  • 40
    • 2342616297 scopus 로고    scopus 로고
    • 11 beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics
    • Sandeep TC, Yau JL, MacLullich AM, Noble J, Deary IJ, Walker BR & Seckl JR 2004 11 beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics. PNAS 101 6734-6739.
    • (2004) PNAS , vol.101 , pp. 6734-6739
    • Sandeep, T.C.1    Yau, J.L.2    MacLullich, A.M.3    Noble, J.4    Deary, I.J.5    Walker, B.R.6    Seckl, J.R.7
  • 41
    • 0344844573 scopus 로고    scopus 로고
    • A rapid screening assay for inhibitors of 11 beta-hydroxysteroid dehydrogenases (11 beta-HSD): Flavanone selectively inhibits 11 beta-HSD1 reductase activity
    • Schweizer RA, Atanasov AG, Frey BM & Odermatt A 2003 A rapid screening assay for inhibitors of 11 beta-hydroxysteroid dehydrogenases (11 beta-HSD): flavanone selectively inhibits 11 beta-HSD1 reductase activity. Molecular and Cellular Endocrinology 212 41-49.
    • (2003) Molecular and Cellular Endocrinology , vol.212 , pp. 41-49
    • Schweizer, R.A.1    Atanasov, A.G.2    Frey, B.M.3    Odermatt, A.4
  • 42
    • 2442513350 scopus 로고    scopus 로고
    • Rapid hepatic metabolism of 7-ketocholesterol by 11β-hydroxysteroid dehydrogenase type 1: Species-specific differences between the rat, human, and hamster enzyme
    • Schweizer RA, Zurcher M, Balazs Z, Dick B & Odermatt A 2004 Rapid hepatic metabolism of 7-ketocholesterol by 11β-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme. Journal of Biological Chemistry 279 18415-18424.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 18415-18424
    • Schweizer, R.A.1    Zurcher, M.2    Balazs, Z.3    Dick, B.4    Odermatt, A.5
  • 43
    • 0037135605 scopus 로고    scopus 로고
    • Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor
    • Stauffer AT, Rochat MK, Dick B, Frey FJ & Odermatt A 2002 Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor. Journal of Biological Chemistry 277 26286-26292.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 26286-26292
    • Stauffer, A.T.1    Rochat, M.K.2    Dick, B.3    Frey, F.J.4    Odermatt, A.5
  • 45
    • 0026095840 scopus 로고
    • The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization
    • Tannin GM, Agarwal AK, Monder C, New MI & White PC 1991 The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization. Journal of Biological Chemistry 266 16653-16658.
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 16653-16658
    • Tannin, G.M.1    Agarwal, A.K.2    Monder, C.3    New, M.I.4    White, P.C.5
  • 47
    • 13844320566 scopus 로고    scopus 로고
    • LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters
    • Wolber G & Langer T 2005 LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters. Journal of Chemical Information and Modeling 45 160-169.
    • (2005) Journal of Chemical Information and Modeling , vol.45 , pp. 160-169
    • Wolber, G.1    Langer, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.