Stereochemical aspects of carbonyl reduction of the original anticancer drug oracin by mouse liver microsomes and purified 11β-hydroxysteroid dehydrogenase type 1

Chemico-Biological Interactions

Volumn 143-144, Issue , 2003, Pages 459-468

  Wsól, Vladimír ^a   Szotáková, Barbora ^a   Skálová, Lenka ^a   Maser, Edmund ^b,c  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c UNIVERSITY OF KIEL   (Germany)

Author keywords

11 HSD 1; Carbonyl reduction; Cooperativity; Cytostatics; Oracin; Stereospecificity

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ANTINEOPLASTIC AGENT; CARBONYL DERIVATIVE; ORACIN;

ANIMAL CELL; CATALYST; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME PURIFICATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; LIVER MICROSOME; MOUSE; NONHUMAN; PROTEIN FUNCTION; STEREOCHEMISTRY; STEREOSPECIFICITY;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ETHANOLAMINES; FEMALE; HYDROXYSTEROID DEHYDROGENASES; ISOQUINOLINES; MICE; MICROSOMES, LIVER; OXIDATION-REDUCTION; STEREOISOMERISM;

ANIMALIA;

EID: 0345073742     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(02)00221-1     Document Type: Conference Paper

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