Prevention of 7-ketocholesterol-induced mitochondrial damage and cell death by calmodulin inhibition

Brain Research

Volumn 1137, Issue 1, 2007, Pages 11-19

  Han, Jeong Ho ^a   Kim, Yun Jeong ^b   Han, Eun Sook ^b   Lee, Chung Soo ^b  

^a Seoul Veterans Hospital   (South Korea)

^b Chung Ang University   (South Korea)

Author keywords

7 Ketocholesterol; Calmodulin antagonist; Mitochondrial permeability transition; PC12 cell; Protection

Indexed keywords

2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; 7 OXOCHOLESTEROL; ACETYLCYSTEINE; CALMIDAZOLIUM; CALMODULIN; CASPASE 3; CYTOCHROME C; GLUTATHIONE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PORPHYRIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; TRIFLUOPERAZINE; TROLOX C; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME RELEASE; MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; CALMODULIN; CASPASE 3; CELL DEATH; CELL SURVIVAL; CYTOCHROMES C; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; GLUTATHIONE; KETOCHOLESTEROLS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; OXIDATIVE STRESS; PC12 CELLS; PERMEABILITY; RATS; REACTIVE OXYGEN SPECIES;

EID: 33846930913     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.12.041     Document Type: Article

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