Dual or triple activation of TLR7, TLR8, and/or TLR9 by single-stranded oligoribonucleotides

Nucleic Acid Therapeutics

Volumn 21, Issue 6, 2011, Pages 423-436

  Forsbach, Alexandra ^a   Samulowitz, Ulrike ^a   Völp, Kirsten ^a   Hofmann, Hans Peter ^a   Noll, Bernhard ^a   Tluk, Sybille ^a   Schmitz, Claudia ^a   Wader, Tanja ^a   Müller, Christian ^a   Podszuweit, Anja ^a   Lohner, Angela ^a   Curdt, Rainer ^a   Uhlmann, Eugen ^a   Vollmer, Jörg ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO 2' DEOXY GUANOSINE; 8 OXO 2' DEOXY GUANOSINE; ALPHA INTERFERON; CHEMOKINE; CHOLESTEROL; CYTOKINE; CYTOSINE; GUANOSINE; INTERFERON; OLIGORIBONUCLEOTIDE; PHOSPHODIESTERASE; PHOSPHOROTHIOIC ACID; SINGLE STRANDED OLIGORIBONUCLEOTIDE; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHIMERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA SEQUENCE; FEMALE; HUMAN; HUMAN CELL; IMMUNE SYSTEM; INNATE IMMUNITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SEQUENCE; RNA STRUCTURE;

ANIMALS; CELLS, CULTURED; CHEMOKINES; CYTOKINES; FEMALE; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON TYPE I; LEUKOCYTES, MONONUCLEAR; MALE; MICE; OLIGORIBONUCLEOTIDES; PHOSPHOROTHIOATE OLIGONUCLEOTIDES; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTOR 9;

EID: 84555178991     PISSN: 21593337     EISSN: None     Source Type: Journal    
DOI: 10.1089/nat.2011.0323     Document Type: Article

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