Properties of mixed backbone oligonucleotides containing 3'-O-methyl ribonucleosides.

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 17, 1999, Pages 2515-2520

  Kumar, Prabhat ^a   Takaku, Hiroshi ^a,b  

^a High Technology Research Center   (Japan)

^b CHIBA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEOSIDE; DNA; OLIGONUCLEOTIDE; RIBONUCLEASE H; RIBONUCLEOSIDE; RNA; SNAKE VENOM;

ARTICLE; CHEMICAL MODIFICATION; DRUG CONFORMATION; DRUG SYNTHESIS; ENZYME STABILITY; ESCHERICHIA COLI; NONHUMAN; REACTION ANALYSIS; SNAKE; THERMOSTABILITY;

BASE SEQUENCE; CIRCULAR DICHROISM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; OLIGONUCLEOTIDES; RIBONUCLEOSIDES;

EID: 0033530118     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00414-X     Document Type: Article

References (26)

1. Uhlmann, E.; Peyman, A. Chem. Rev. 1990, 90, 544.
2. Wickstrom, E.J. Biochem.Biophy. Meth. 1986, 13, 97.
3. Cazenave, C.; Chevrier, M; Thuong, N.T.; Helene, C. Nucleic Acids Res. 1987,15, 10507.
4. Crooke, S.T.; Lebleu, B., Ed.; Antisense Research and Application; CRC Press: Boca Raton, FL, 1993.
5. Sproat, B.S.; Lamond, A.I.; Beijer, B.; Neuner, P.; Ryder, U. Nucleic Acids Res. 1989, 17, 3373.
6. Cummins, L.L.; Owens, S.P.; Risen, L.M.; Lesnick, E.A.; Freier, S.M.; McGee,D.; Guinosso, C.J.; Cook, P.D. Nucleic Acids Res. 1995, 23, 2019.
7. Wagner, R.W.; Matteucci, M.D.; Jason, G.L.; Gutierrez, A.J.; Moulds, C.; Froehler, B.C. Science 1993, 260, 1510.
8. Hosono, K.; Kuwasaki, T.; Inagawa, T.; Takai, K.; Nakashima, H.; Saito, T.; Yamamoto, N.; Takaku, H. Antiviral Chem. Chemotherapy 1996, 7, 86.
9. Freier, S.M.; Altmann, K.-H. Nucleic Acids Res. 1997, 25, 4429.
10. Ushijima, K.; Ishibashi, T., Yamakawa, H.; Tsukahara, S.; Takai, T.; Maruyama, T.; Takaku, H. Biochemistry 1999, 38, 6570.
11. Ecker, D.J.; Vickers, T.A.; Bruice, T.W.; Freier, S.M.; Jenison, R.D.; Manoharan, M.; Zoundes, M. Science 1992, 257, 958.
12. Lesnick, E.A.; Guinosso, C.J.; Kawasaki, A. M.; Sasmor, H.; Zounes, M.; Cummins, L.L.; Ecker, K.J.; Cook, P.D.; Freier, S.M. Biochemistry 1993, 32, 7832.
13. Larrouy, B.; Boiziau, C.; Sproat, B.; Toulme, J.-J. Nucleic Acids Res. 1995, 23, 3434.
14. Dean, N.M.; Mckay, R.; Condon, T.P.; Bennett, C.F. J. Biol. Chem. 1994, 269, 16416.
15. Johnston, M.I,; Torrence, P.F. In Interferons: Mechanism of Production and Action ; Friedman, R.M., Ed.; Elsevier : Amsterdam, 1984; vol. 3, pp 189-298.
16. Kierzek, R.; He, L.; Turner, D.H. Nucleic Acids Res. 1992, 20, 1685.
17. Bhan, P.; Bhan, A.; Hong, M.; Hartwell, J.G.; Saunders. J.M.; Hoke, G.D. Nucleic Acids Res. 1997, 25, 3310.
18. Kandimalia, E.R.; Manning, A.; Zhao, Q.; Shaw, D.R.; Bryn, R.A.; Sasisekharan, V.; Agrawal, S. Nucleic Acids Res. 1997, 25, 370.
19. a) Jones, R.A. In Oligonucleotide Synthesis: A Practical Approach; Gait, M.J., Ed.; IRL Press: Oxford, 1984; chapt. 2, pp 23-34.
20. b) Atkinson, T.; Smith, M. ibid ; chapt. 3, pp 35-81.
21. 3) of 3'-O-MeA, δ : 133, 135 ppm.
22. Giannaris, P.A.; Damha, M.J. Nucleic Acids Res. 1993, 20, 4742.
23. Saenger, W. In Principles of Nucleic Acid Structure; Cantor, C.R., Ed.; Springer Verlag: New York, 1984.
24. Wang, A.C.; Kim, S.G.; Flynn, P.F.; Chou, S.-H.; Orban, J.; Reid, B.R. Biochemistry 1992, 31, 3940.
25. Clark, C.L.; Cecil, P.K.; Singh, D.; Gray, D.M. Nucleic Acids Res. 1997, 25, 4098.
26. Li, G.; Xiao, W.; Torrence, P.F. J. Med. Chem. 1997, 40, 2959.