Use of thermolytic protective groups to prevent G-tetrad formation in CpG ODN type D: Structural studies and immunomodulatory activity in primates

Nucleic Acids Research

Volumn 34, Issue 22, 2006, Pages 6488-6495

  Puig, Montserrat ^a   Grajkowski, Andrzej ^a   Boczkowska, Malgorzata ^b   Ausín, Cristina ^a   Beaucage, Serge L ^a   Verthelyi, Daniela ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 6; PRODRUG; TOLL LIKE RECEPTOR 9;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; DRUG DESIGN; DRUG SYNTHESIS; ENDOSOME; HUMAN; HUMAN CELL; IMMUNITY; IMMUNOMODULATION; IN VIVO STUDY; LEISHMANIA MAJOR; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; RHESUS MONKEY; SKIN LEISHMANIASIS; THERMOREGULATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CULTURE MEDIA; DNA; GUANINE; HUMANS; LEISHMANIASIS, CUTANEOUS; MACACA MULATTA; OLIGODEOXYRIBONUCLEOTIDES; PRODRUGS; TEMPERATURE;

LEISHMANIA MAJOR; MACACA; MACACA MULATTA; PRIMATES;

EID: 33845871431     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl867     Document Type: Article

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