Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons

NeuroToxicology

Volumn 32, Issue 6, 2011, Pages 845-856

  Jantas, D ^a   Lorenc Koci, E ^a   Kubera, M ^a   Lason, W ^a,b  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

AIF; Calpains; Calpeptin; MDL28170; Neuronal apoptosis; PD98052; U0126

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; [1 [(1 FORMYL 2 PHENYLETHYL)CARBAMOYL] 2 METHYLPROPYL]CARBAMIC ACID BENZYL ESTER; APOPTOSIS INDUCING FACTOR; CALPAIN; CALPEPTIN; CASPASE 3; CYSTEINE PROTEINASE INHIBITOR; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PD 98052; PROTEIN SERINE THREONINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATTENUATION; BRAIN NERVE CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; MOUSE; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BUTADIENES; CALPAIN; CASPASE 3; CELLS, CULTURED; CEREBRAL CORTEX; CYSTEINE PROTEINASE INHIBITORS; CYTOPROTECTION; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GESTATIONAL AGE; IN SITU NICK-END LABELING; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURONS; NEUROPROTECTIVE AGENTS; NITRILES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; SPECTRIN; TIME FACTORS;

EID: 80055070148     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2011.05.013     Document Type: Article

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