Prolonged activation of ERK triggers glutamate-induced apoptosis of astrocytes: Neuroprotective effect of FK506

Journal of Neurochemistry

Volumn 113, Issue 4, 2010, Pages 904-918

  Szydlowska, Kinga ^a   Gozdz, Agata ^a   Dabrowski, Michal ^a   Zawadzka, Malgorzata ^a   Kaminska, Bozena ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

Apoptosis; Astrocytes; Extracellular signal regulated kinases 1 2; FK506; Glutamate toxicity; Glutamate transporters; Ischemia

Indexed keywords

ASPARTIC ACID DERIVATIVE; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TACROLIMUS; UO 126;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; CORPUS STRIATUM; CYTOPLASM; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME SPECIFICITY; GENE EXPRESSION PROFILING; GENETIC TRANSFECTION; MALE; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; ASTROCYTES; BUTADIENES; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUTAMIC ACID; HYPOXIA-ISCHEMIA, BRAIN; IMMUNOSUPPRESSIVE AGENTS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUROPROTECTIVE AGENTS; NITRILES; RATS; RATS, WISTAR; TACROLIMUS;

ANIMALIA;

EID: 77950939997     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06656.x     Document Type: Article

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