Effect of an experimental proteasome inhibitor on the cytoskeleton, cytosolic protein turnover, and induction in the neuronal cells in vitro

NeuroToxicology

Volumn 29, Issue 2, 2008, Pages 232-243

  Csizmadia, Vilmos ^a   Raczynski, Arek ^a   Csizmadia, Eva ^a   Fedyk, Eric R ^a   Rottman, James ^a   Alden, Carl L ^a  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

GT 1 neurons; Immunohistochemistry; Protein aggregates; Stress response; Ubiquitin proteasome system

Indexed keywords

ACTIN; GAMMA TUBULIN; HEAT SHOCK PROTEIN; LACTACYSTIN; PROTEASOME INHIBITOR; UBIQUITIN; VIMENTIN;

AGGRESOME; ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOSKELETON; DNA FRAGMENTATION; ENDOPLASMIC RETICULUM; HOMEOSTASIS; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MICROFILAMENT; MICROTUBULE; MOUSE; NERVE CELL; NERVE CONDUCTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN METABOLISM; UPREGULATION;

ACETYLCYSTEINE; ACTINS; ANIMALS; BLOTTING, WESTERN; CELL DEATH; CELL LINE; CELL SURVIVAL; CYSTEINE PROTEINASE INHIBITORS; CYTOSKELETON; CYTOSOL; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MICE; MICROSCOPY, FLUORESCENCE; NERVE TISSUE PROTEINS; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; TIME FACTORS; TUBULIN; UBIQUITIN;

MURINAE;

EID: 39749107470     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2007.11.003     Document Type: Article

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