Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons

Journal of Physiology and Pharmacology

Volumn 59, Issue 3, 2008, Pages 457-475

  Leskiewicz, M ^a   Jantas, D ^a   Budziszewska, B ^a   Lason, W ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

Allopregnanolone; Caspase 3 activity; Dehydroepiandrosterone; Dehydroepiandrosterone sulfate; Glutamate; Hoechst's staining; Lactate dehydrogenase; MTT; Pregnenolone; Primary cortical cells; Staurosporine

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GLUTAMIC ACID; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N METHYL DEXTRO ASPARTIC ACID; NEUROSTEROID; PRASTERONE; PRASTERONE SULFATE; PREGNENOLONE; STAUROSPORINE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; CELL DEATH; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXCITOTOXICITY; FEMALE; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NERVE CELL CULTURE; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL DEATH; CEREBRAL CORTEX; DEHYDROEPIANDROSTERONE; DEHYDROEPIANDROSTERONE SULFATE; ENZYME INHIBITORS; EXCITATORY AMINO ACIDS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUTAMIC ACID; MEMBRANE POTENTIALS; MICE; N-METHYLASPARTATE; NEURONS; NEUROTRANSMITTER AGENTS; PREGNANOLONE; PREGNENOLONE; REACTIVE OXYGEN SPECIES; STAUROSPORINE; STEROIDS;

EID: 53649088773     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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