-
1
-
-
0030878073
-
Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra
-
Alam ZI, Jenner A, Daniel SE, Lees AJ, Cairns N, Marsden CD, Jenner P Halliwell B. 1997. Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J Neurochem 69:1196-1203.
-
(1997)
J Neurochem
, vol.69
, pp. 1196-1203
-
-
Alam, Z.I.1
Jenner, A.2
Daniel, S.E.3
Lees, A.J.4
Cairns, N.5
Marsden, C.D.6
Jenner, P.7
Halliwell, B.8
-
2
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H, Tredici KD, Rub U, de Vos RA, Jansen Steur EN, Braak E. 2003. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24:197-211.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Tredici, K.D.2
Rub, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
3
-
-
0035839573
-
Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion
-
Bulteau AL, Lundberg KC, Humphries KM, Sadek HA, Szweda PA, Friguet B, Szweda LI. 1999. Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. J Biol Chem 276:30057-30063.
-
(1999)
J Biol Chem
, vol.276
, pp. 30057-30063
-
-
Bulteau, A.L.1
Lundberg, K.C.2
Humphries, K.M.3
Sadek, H.A.4
Szweda, P.A.5
Friguet, B.6
Szweda, L.I.7
-
4
-
-
4644290985
-
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease
-
Chartier-Harlin MC, Kachergus J, Roumier C, Mouroux V, Douay X, Lincoln S, Levecque C, Larvor L, Andrieux J, Hulihan M, Waucquier N, Defebvre L, Amouyel P, Farrer M, Destee A. 2004. Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 364:1167-1169.
-
(2004)
Lancet
, vol.364
, pp. 1167-1169
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Andrieux, J.9
Hulihan, M.10
Waucquier, N.11
Defebvre, L.12
Amouyel, P.13
Farrer, M.14
Destee, A.15
-
5
-
-
0141987860
-
The ubiquitin proteasome system in neurodegenerative diseases. Sometimes the chicken, sometimes the egg
-
Ciechanover A, Brundin P. 2003. The ubiquitin proteasome system in neurodegenerative diseases. Sometimes the chicken, sometimes the egg. Neuron 40:427-446.
-
(2003)
Neuron
, vol.40
, pp. 427-446
-
-
Ciechanover, A.1
Brundin, P.2
-
6
-
-
0032816549
-
The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease
-
Damier P, Hirsch EC, Agid Y, Graybiel AM. 1999. The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain 122:1437-1448.
-
(1999)
Brain
, vol.122
, pp. 1437-1448
-
-
Damier, P.1
Hirsch, E.C.2
Agid, Y.3
Graybiel, A.M.4
-
7
-
-
0023655369
-
Protein damage and degradation by oxygen radicals. I. General aspects
-
Davies KJ. 1987. Protein damage and degradation by oxygen radicals. I. General aspects. J Biol Chem 262:9895-9901.
-
(1987)
J Biol Chem
, vol.262
, pp. 9895-9901
-
-
Davies, K.J.1
-
8
-
-
0023655531
-
Protein damage and degradation by oxygen radicals. III. Modification of secondary and tertiary structure
-
Davies KJ, Delsignore ME. 1987. Protein damage and degradation by oxygen radicals. III. Modification of secondary and tertiary structure. J Biol Chem 262:9908-9913.
-
(1987)
J Biol Chem
, vol.262
, pp. 9908-9913
-
-
Davies, K.J.1
Delsignore, M.E.2
-
9
-
-
0023655407
-
Protein damage and degradation by oxygen radicals. II. Modification of amino acids
-
Davies KJ, Delsignore ME, Lin SW. 1987. Protein damage and degradation by oxygen radicals. II. Modification of amino acids. J Biol Chem 262:9902-9907.
-
(1987)
J Biol Chem
, vol.262
, pp. 9902-9907
-
-
Davies, K.J.1
Delsignore, M.E.2
Lin, S.W.3
-
10
-
-
0033529596
-
The proteasome, a novel protease regulated by multiple mechanisms
-
DeMartino GN, Slaughter CA. 1999. The proteasome, a novel protease regulated by multiple mechanisms. J Biol Chem 274:22123-22126.
-
(1999)
J Biol Chem
, vol.274
, pp. 22123-22126
-
-
DeMartino, G.N.1
Slaughter, C.A.2
-
11
-
-
0027952849
-
Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: An HPLC and ESR study
-
Dexter DT, Holley AE, Flitter WD, Slater TF, Wells FR, Daniel SE, Lees AJ, Jenner P, Marsden CD. 1994. Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: An HPLC and ESR study. Mov Disord 9:92-97.
-
(1994)
Mov Disord
, vol.9
, pp. 92-97
-
-
Dexter, D.T.1
Holley, A.E.2
Flitter, W.D.3
Slater, T.F.4
Wells, F.R.5
Daniel, S.E.6
Lees, A.J.7
Jenner, P.8
Marsden, C.D.9
-
12
-
-
0037860832
-
Role of the proteasome in protein oxidation and neural viability following low-level oxidative stress
-
Ding Q, Reinacker K, Dimayuga E, Nukala V, Drake J, Butterfield DA, Dunn JC, Martin S, Bruce-Keller AJ, Keller JN. 2003. Role of the proteasome in protein oxidation and neural viability following low-level oxidative stress. FEBS Lett 546:228-232.
-
(2003)
FEBS Lett
, vol.546
, pp. 228-232
-
-
Ding, Q.1
Reinacker, K.2
Dimayuga, E.3
Nukala, V.4
Drake, J.5
Butterfield, D.A.6
Dunn, J.C.7
Martin, S.8
Bruce-Keller, A.J.9
Keller, J.N.10
-
13
-
-
0035939105
-
The expression of mRNAs for the proteasome complex is developmentally regulated in the rat mesencephalon
-
El-Khodor BF, Kholodilov NG, Yarygina O, Burke RE. 2001. The expression of mRNAs for the proteasome complex is developmentally regulated in the rat mesencephalon. Brain Res Dev Brain Res 129:47-56.
-
(2001)
Brain Res Dev Brain Res
, vol.129
, pp. 47-56
-
-
El-Khodor, B.F.1
Kholodilov, N.G.2
Yarygina, O.3
Burke, R.E.4
-
14
-
-
0024413057
-
ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin
-
Eytan E, Ganoth D, Armon T, Hershko A. 1989. ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin. Proc Natl Acad Sci USA 86:7751-7755.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7751-7755
-
-
Eytan, E.1
Ganoth, D.2
Armon, T.3
Hershko, A.4
-
15
-
-
0037306431
-
Differential expression of ubiquitin and proteasome-dependent pathway components in rat tissues
-
Farout L, Lamare M, Clavel S, Briand M, Briand Y. 2003. Differential expression of ubiquitin and proteasome-dependent pathway components in rat tissues. Comp Biochem Physiol B Biochem Mol Biol 134:297-305.
-
(2003)
Comp Biochem Physiol B Biochem Mol Biol
, vol.134
, pp. 297-305
-
-
Farout, L.1
Lamare, M.2
Clavel, S.3
Briand, M.4
Briand, Y.5
-
16
-
-
0031962268
-
Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay
-
Floor E, Wetzel MG. 1998. Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay. J Neurochem 70:268-275.
-
(1998)
J Neurochem
, vol.70
, pp. 268-275
-
-
Floor, E.1
Wetzel, M.G.2
-
17
-
-
0029981526
-
Neuropathology of Parkinson's disease
-
Forno LS. 1996. Neuropathology of Parkinson's disease. J Neuropathol Exp Neurol 55:259-272.
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 259-272
-
-
Forno, L.S.1
-
18
-
-
0036260836
-
Brain proteasomal function in sporadic Parkinson's disease and related disorders
-
Furukawa Y, Vigouroux S, Wong H, Guttman M, Rajput AH, Ang L, Briand M, Kish SJ, Briand Y. 2002. Brain proteasomal function in sporadic Parkinson's disease and related disorders. Ann Neurol 51:779-782.
-
(2002)
Ann Neurol
, vol.51
, pp. 779-782
-
-
Furukawa, Y.1
Vigouroux, S.2
Wong, H.3
Guttman, M.4
Rajput, A.H.5
Ang, L.6
Briand, M.7
Kish, S.J.8
Briand, Y.9
-
19
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
-
Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM. 2000. Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science 290:985-989.
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.9
-
20
-
-
0023898945
-
The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease
-
Gibb WR, Lees AJ. 1988. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry 51:745-752.
-
(1988)
J Neurol Neurosurg Psychiatry
, vol.51
, pp. 745-752
-
-
Gibb, W.R.1
Lees, A.J.2
-
21
-
-
33847066706
-
Functions of the proteasome: From protein degradation and immune surveillance to cancer therapy
-
Goldberg AL. 2007. Functions of the proteasome: From protein degradation and immune surveillance to cancer therapy. Biochem Soc Trans 35:12-17.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 12-17
-
-
Goldberg, A.L.1
-
22
-
-
0031939204
-
Protein nitration in Parkinson's disease
-
Good PF, Hsu A, Werner P, Perl DP, Olanow CW. 1998. Protein nitration in Parkinson's disease. J Neuropathol Exp Neurol 57:338-342.
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 338-342
-
-
Good, P.F.1
Hsu, A.2
Werner, P.3
Perl, D.P.4
Olanow, C.W.5
-
23
-
-
4344681293
-
Pathogenetic mechanisms of parkin in Parkinson's disease
-
Hattori N, Mizuno Y. 2004. Pathogenetic mechanisms of parkin in Parkinson's disease. Lancet 364:722-724.
-
(2004)
Lancet
, vol.364
, pp. 722-724
-
-
Hattori, N.1
Mizuno, Y.2
-
25
-
-
0030614644
-
Neuronal vulnerability in Parkinson's disease
-
Hirsch EC, Faucheux B, Damier P, Mouatt-Prigent A, Agid Y. 1997. Neuronal vulnerability in Parkinson's disease. J Neural Transm Suppl 50:79-88.
-
(1997)
J Neural Transm
, Issue.SUPPL. 50
, pp. 79-88
-
-
Hirsch, E.C.1
Faucheux, B.2
Damier, P.3
Mouatt-Prigent, A.4
Agid, Y.5
-
26
-
-
0041430614
-
Dysfunction of mitochondrial complex I and the proteasome: Interactions between two biochemical deficits in a cellular model of Parkinson's disease
-
Hoglinger GU, Carrard G, Michel PP, Medja F, Lombes A, Ruberg M, Friguet B, Hirsch EC. 2003. Dysfunction of mitochondrial complex I and the proteasome: Interactions between two biochemical deficits in a cellular model of Parkinson's disease. J Neurochem 86:1297-1307.
-
(2003)
J Neurochem
, vol.86
, pp. 1297-1307
-
-
Hoglinger, G.U.1
Carrard, G.2
Michel, P.P.3
Medja, F.4
Lombes, A.5
Ruberg, M.6
Friguet, B.7
Hirsch, E.C.8
-
28
-
-
0037469979
-
Effect of proteasome inhibitor on cultured mesencephalic dopaminergic neurons
-
Kikuchi S, Shinpo K, Tsuji S, Takeuchi M, Yamagishi S, Makita Z, Niino M, Yabe I, Tashiro K. 2003. Effect of proteasome inhibitor on cultured mesencephalic dopaminergic neurons. Brain Res 964:228-236.
-
(2003)
Brain Res
, vol.964
, pp. 228-236
-
-
Kikuchi, S.1
Shinpo, K.2
Tsuji, S.3
Takeuchi, M.4
Yamagishi, S.5
Makita, Z.6
Niino, M.7
Yabe, I.8
Tashiro, K.9
-
29
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N. 1998. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392:605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
30
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R, Kuhn W, Muller T, Woitalla D, Graeber M, Kosel S, Przuntek H, Epplen JT, Schols L, Riess O. 1998. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet 18:106-108.
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
31
-
-
0032531924
-
Parkinson's disease. Second of two parts
-
Lang AE, Lozano AM. 1998a. Parkinson's disease. Second of two parts. N Engl J Med 339:1130-1143.
-
(1998)
N Engl J Med
, vol.339
, pp. 1130-1143
-
-
Lang, A.E.1
Lozano, A.M.2
-
32
-
-
0032497504
-
Parkinson's disease. First of two parts
-
Lang AE, Lozano AM. 1998b. Parkinson's disease. First of two parts. N Engl J Med 339:1044-1053.
-
(1998)
N Engl J Med
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
33
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy E, Boyer R, Auburger G, Leube B, Ulm G, Mezey E, Harta G, Brownstein MJ, Jonnalagada S, Chernova T, Dehejia A, Lavedan C, Gasser T, Steinbach PJ, Wilkinson KD, Polymeropoulos MH. 1998. The ubiquitin pathway in Parkinson's disease. Nature 395:451-452.
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
Mezey, E.6
Harta, G.7
Brownstein, M.J.8
Jonnalagada, S.9
Chernova, T.10
Dehejia, A.11
Lavedan, C.12
Gasser, T.13
Steinbach, P.J.14
Wilkinson, K.D.15
Polymeropoulos, M.H.16
-
34
-
-
20744442130
-
A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: Implications for pathogenesis of Parkinson's disease
-
Liu CW, Giasson BI, Lewis KA, Lee VM, Demartino GN, Thomas PJ. 2005. A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: Implications for pathogenesis of Parkinson's disease. J Biol Chem 280:22670-22678.
-
(2005)
J Biol Chem
, vol.280
, pp. 22670-22678
-
-
Liu, C.W.1
Giasson, B.I.2
Lewis, K.A.3
Lee, V.M.4
Demartino, G.N.5
Thomas, P.J.6
-
35
-
-
0037227397
-
Altered proteasomal function in sporadic Parkinson's disease
-
McNaught KS, Belizaire R, Isacson O, Jenner P, Olanow CW. 2003. Altered proteasomal function in sporadic Parkinson's disease. Exp Neurol 179:38-45.
-
(2003)
Exp Neurol
, vol.179
, pp. 38-45
-
-
McNaught, K.S.1
Belizaire, R.2
Isacson, O.3
Jenner, P.4
Olanow, C.W.5
-
36
-
-
0035910634
-
Proteasomal function is impaired in substantia nigra in Parkinson's disease
-
McNaught KS, Jenner P. 2001. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett 297:191-194.
-
(2001)
Neurosci Lett
, vol.297
, pp. 191-194
-
-
McNaught, K.S.1
Jenner, P.2
-
37
-
-
0037378898
-
Proteolytic stress: A unifying concept in the etiopathogenesis of familial and sporadic Parkinson's disease
-
McNaught KS, Olanow CW. 2003. Proteolytic stress: A unifying concept in the etiopathogenesis of familial and sporadic Parkinson's disease. Ann Neurol 53(3 Suppl 1):S73-S86.
-
(2003)
Ann Neurol
, vol.53
, Issue.3 SUPPL. 1
-
-
McNaught, K.S.1
Olanow, C.W.2
-
38
-
-
0036456584
-
Aggresome-related biogenesis of Lewy bodies
-
McNaught KS, Shashidharan P, Perl DP, Jenner P, Olanow CW. 2002a. Aggresome-related biogenesis of Lewy bodies. Eur J Neurosci 16:2136-2148.
-
(2002)
Eur J Neurosci
, vol.16
, pp. 2136-2148
-
-
McNaught, K.S.1
Shashidharan, P.2
Perl, D.P.3
Jenner, P.4
Olanow, C.W.5
-
39
-
-
0036316947
-
Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures
-
McNaught KSP, Mytilineou C, JnoBaptiste R, Jabut J, Shashidharan P, Jenner P, Olanow CW. 2002b. Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures. J Neurochem 81:301-306.
-
(2002)
J Neurochem
, vol.81
, pp. 301-306
-
-
McNaught, K.S.P.1
Mytilineou, C.2
JnoBaptiste, R.3
Jabut, J.4
Shashidharan, P.5
Jenner, P.6
Olanow, C.W.7
-
40
-
-
0037821846
-
Inhibition of proteasome activity induces concerted expression of proteasome genes and de novo formation of Mammalian proteasomes
-
Meiners S, Heyken D, Weller A, Ludwig A, Stangl K, Kloetzel PM, Kruger E. 2003. Inhibition of proteasome activity induces concerted expression of proteasome genes and de novo formation of Mammalian proteasomes. J Biol Chem 278:21517-21525.
-
(2003)
J Biol Chem
, vol.278
, pp. 21517-21525
-
-
Meiners, S.1
Heyken, D.2
Weller, A.3
Ludwig, A.4
Stangl, K.5
Kloetzel, P.M.6
Kruger, E.7
-
41
-
-
0029815028
-
Immunohistochemical distribution and electron microscopic subcellular localization of the proteasome in the rat CNS
-
Mengual E, Arizti P, Rodrigo J, Gimenez-Amaya JM, Castano JG. 1996. Immunohistochemical distribution and electron microscopic subcellular localization of the proteasome in the rat CNS. J Neurosci 16:6331-6341.
-
(1996)
J Neurosci
, vol.16
, pp. 6331-6341
-
-
Mengual, E.1
Arizti, P.2
Rodrigo, J.3
Gimenez-Amaya, J.M.4
Castano, J.G.5
-
43
-
-
0344758360
-
Glial cells mediate toxicity in glutathione-depleted mesencephalic cultures
-
Mytilineou C, Kokotos Leonardi ET, Kramer BC, Jamindar T, Olanow CW. 1999. Glial cells mediate toxicity in glutathione-depleted mesencephalic cultures. J Neurochem 73:112-119.
-
(1999)
J Neurochem
, vol.73
, pp. 112-119
-
-
Mytilineou, C.1
Kokotos Leonardi, E.T.2
Kramer, B.C.3
Jamindar, T.4
Olanow, C.W.5
-
44
-
-
7944226117
-
Inhibition of proteasome activity sensitizes dopamine neurons to protein alterations and oxidative stress
-
Mytilineou C, McNaught KS, Shashidharan P, Yabut J, Baptiste RJ, Parnandi A, Olanow CW. 2004. Inhibition of proteasome activity sensitizes dopamine neurons to protein alterations and oxidative stress. J Neural Transm 111:1237-1251.
-
(2004)
J Neural Transm
, vol.111
, pp. 1237-1251
-
-
Mytilineou, C.1
McNaught, K.S.2
Shashidharan, P.3
Yabut, J.4
Baptiste, R.J.5
Parnandi, A.6
Olanow, C.W.7
-
45
-
-
0037309436
-
Levodopa is toxic to dopamine neurons in an in vitro but not an in vivo model of oxidative stress
-
Mytilineou C, Walker RH, JnoBaptiste R, Olanow CW. 2003. Levodopa is toxic to dopamine neurons in an in vitro but not an in vivo model of oxidative stress. J Pharmacol Exp Ther 304:792-800.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 792-800
-
-
Mytilineou, C.1
Walker, R.H.2
JnoBaptiste, R.3
Olanow, C.W.4
-
46
-
-
33845994064
-
p53 Mediates non-transcriptional cell death in dopaminergic cells in response to proteasome inhibition
-
Nair VD, McNaught KS, Gonzalez-Maeso J, Sealfon SC, Olanow CW. 2006. p53 Mediates non-transcriptional cell death in dopaminergic cells in response to proteasome inhibition. J Biol Chem 281:39550-39560.
-
(2006)
J Biol Chem
, vol.281
, pp. 39550-39560
-
-
Nair, V.D.1
McNaught, K.S.2
Gonzalez-Maeso, J.3
Sealfon, S.C.4
Olanow, C.W.5
-
47
-
-
0034703630
-
Tissue distribution of constitutive proteasomes, immunoproteasomes, and PA28 in rats
-
Noda C, Tanahashi N, Shimbara N, Hendil KB, Tanaka K. 2000. Tissue distribution of constitutive proteasomes, immunoproteasomes, and PA28 in rats. Biochem Biophys Res Commun 277:348-354.
-
(2000)
Biochem Biophys Res Commun
, vol.277
, pp. 348-354
-
-
Noda, C.1
Tanahashi, N.2
Shimbara, N.3
Hendil, K.B.4
Tanaka, K.5
-
48
-
-
0029031709
-
The anterior olfactory nucleus in Parkinson's disease
-
Pearce RK, Hawkes CH, Daniel SE. 1995. The anterior olfactory nucleus in Parkinson's disease. Mov Disord 10:283-287.
-
(1995)
Mov Disord
, vol.10
, pp. 283-287
-
-
Pearce, R.K.1
Hawkes, C.H.2
Daniel, S.E.3
-
49
-
-
0037137702
-
Parkin protects against the toxicity associated with mutant alphasynuclein: Proteasome dysfunction selectively affects catecholaminergic neurons
-
Petrucelli L, O'Farrell C, Lockhart PJ, Baptista M, Kehoe K, Vink L, Choi P, Wolozin B, Farrer M, Hardy J, Cookson MR. 2002. Parkin protects against the toxicity associated with mutant alphasynuclein: Proteasome dysfunction selectively affects catecholaminergic neurons. Neuron 36:1007-1019.
-
(2002)
Neuron
, vol.36
, pp. 1007-1019
-
-
Petrucelli, L.1
O'Farrell, C.2
Lockhart, P.J.3
Baptista, M.4
Kehoe, K.5
Vink, L.6
Choi, P.7
Wolozin, B.8
Farrer, M.9
Hardy, J.10
Cookson, M.R.11
-
50
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, Di Iorio G, Golbe LI, Nussbaum RL. 1997. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
51
-
-
33750618682
-
Comparison of the neurotoxic effects of proteasomal inhibitors in primary mesencephalic cultures
-
Reaney SH, Johnston LC, Langston WJ, Di Monte DA. 2006. Comparison of the neurotoxic effects of proteasomal inhibitors in primary mesencephalic cultures. Exp Neurol 202:434-440.
-
(2006)
Exp Neurol
, vol.202
, pp. 434-440
-
-
Reaney, S.H.1
Johnston, L.C.2
Langston, W.J.3
Di Monte, D.A.4
-
52
-
-
0032212875
-
Comparative resistance of the 20S and 26S proteasome to oxidative stress
-
Reinheckel T, Sitte N, Ullrich O, Kuckelkorn U, Davies KJ, Grune T. 1998. Comparative resistance of the 20S and 26S proteasome to oxidative stress. Biochem J 335:637-642.
-
(1998)
Biochem J
, vol.335
, pp. 637-642
-
-
Reinheckel, T.1
Sitte, N.2
Ullrich, O.3
Kuckelkorn, U.4
Davies, K.J.5
Grune, T.6
-
53
-
-
20144381356
-
Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate iHSP, following proteasomal inhibition
-
Rideout HJ, Lang-Rollin ICJ, Savalle M, Stefanis L. 2005. Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate iHSP, following proteasomal inhibition. J Neurochem 93:1304-1313.
-
(2005)
J Neurochem
, vol.93
, pp. 1304-1313
-
-
Rideout, H.J.1
Lang-Rollin, I.C.J.2
Savalle, M.3
Stefanis, L.4
-
54
-
-
0025640845
-
Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease
-
Schapira AH, Mann VM, Cooper JM, Dexter D, Daniel SE, Jenner P, Clark JB, Marsden CD. 1990. Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease. J Neurochem 55:2142-2145.
-
(1990)
J Neurochem
, vol.55
, pp. 2142-2145
-
-
Schapira, A.H.1
Mann, V.M.2
Cooper, J.M.3
Dexter, D.4
Daniel, S.E.5
Jenner, P.6
Clark, J.B.7
Marsden, C.D.8
-
55
-
-
0242362280
-
An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH-SY5Y cells
-
Shamoto-Nagai M, Maruyama W, Kato Y, Isobe K, Tanaka M, Naoi M, Osawa T. 2003. An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH-SY5Y cells. J Neurosci Res 74:589-597.
-
(2003)
J Neurosci Res
, vol.74
, pp. 589-597
-
-
Shamoto-Nagai, M.1
Maruyama, W.2
Kato, Y.3
Isobe, K.4
Tanaka, M.5
Naoi, M.6
Osawa, T.7
-
56
-
-
0034769477
-
Removal of oxidatively damaged proteins from lens cells by the ubiquitin-proteasome pathway
-
Shang F, Nowell TR Jr, Taylor A. 2001. Removal of oxidatively damaged proteins from lens cells by the ubiquitin-proteasome pathway. Exp Eye Res 73:229-238.
-
(2001)
Exp Eye Res
, vol.73
, pp. 229-238
-
-
Shang, F.1
Nowell Jr, T.R.2
Taylor, A.3
-
57
-
-
0037414834
-
Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome
-
Shringarpure R, Grune T, Mehlhase J, Davies KJ. 2003. Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome. J Biol Chem 278:311-318.
-
(2003)
J Biol Chem
, vol.278
, pp. 311-318
-
-
Shringarpure, R.1
Grune, T.2
Mehlhase, J.3
Davies, K.J.4
-
58
-
-
0028075410
-
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
-
Sian J, Dexter DT, Lees AJ, Daniel S, Agid Y, Javoy-Agid F, Jenner P, Marsden CD. 1994. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol 36:348-355.
-
(1994)
Ann Neurol
, vol.36
, pp. 348-355
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
Daniel, S.4
Agid, Y.5
Javoy-Agid, F.6
Jenner, P.7
Marsden, C.D.8
-
59
-
-
0242300619
-
alpha-Synuclein locus triplication causes Parkinson's disease
-
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, Hulihan M, Peuralinna T, Dutra A, Nussbaum R, Lincoln S, Crawley A, Hanson M, Maraganore D, Adler C, Cookson MR, Muenter M, Baptista M, Miller D, Blancato J, Hardy J, Gwinn-Hardy K. 2003. alpha-Synuclein locus triplication causes Parkinson's disease. Science 302:841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
60
-
-
0038413759
-
Aggregated and monomeric alpha-synuclein bind to the S6′ proteasomal protein and inhibit proteasomal function
-
Snyder H, Mensah K, Theisler C, Lee JM, Matouschek A, Wolozin B. 2003. Aggregated and monomeric alpha-synuclein bind to the S6′ proteasomal protein and inhibit proteasomal function. J Biol Chem 278:11753-11759.
-
(2003)
J Biol Chem
, vol.278
, pp. 11753-11759
-
-
Snyder, H.1
Mensah, K.2
Theisler, C.3
Lee, J.M.4
Matouschek, A.5
Wolozin, B.6
-
61
-
-
0035894855
-
Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death
-
Stefanis L, Larsen KE, Rideout HJ, Sulzer D, Greene LA. 2001. Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. J Neurosci 21:9549-9560.
-
(2001)
J Neurosci
, vol.21
, pp. 9549-9560
-
-
Stefanis, L.1
Larsen, K.E.2
Rideout, H.J.3
Sulzer, D.4
Greene, L.A.5
-
62
-
-
0035870881
-
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
-
Tanaka Y, Engelender S, Igarashi S, Rao RK, Wanner T, Tanzi RE, Sawa A, Dawson VL, Dawson TM, Ross CA. 2001. Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Hum Mol Genet 10:919-926.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 919-926
-
-
Tanaka, Y.1
Engelender, S.2
Igarashi, S.3
Rao, R.K.4
Wanner, T.5
Tanzi, R.E.6
Sawa, A.7
Dawson, V.L.8
Dawson, T.M.9
Ross, C.A.10
-
63
-
-
0242666359
-
Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function
-
Tofaris GK, Razzaq A, Ghetti B, Lilley K, Spillantini MG. 2003. Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function. J Biol Chem 278:44405-44411.
-
(2003)
J Biol Chem
, vol.278
, pp. 44405-44411
-
-
Tofaris, G.K.1
Razzaq, A.2
Ghetti, B.3
Lilley, K.4
Spillantini, M.G.5
-
64
-
-
0035824651
-
Sensitivity of mammalian cells expressing mutant ubiquitin to protein damaging agents
-
Tsirigotis M, Zhang M, Chiu RK, Wouters BG, Gray DA. 2001. Sensitivity of mammalian cells expressing mutant ubiquitin to protein damaging agents. J Biol Chem 276:46073-46078.
-
(2001)
J Biol Chem
, vol.276
, pp. 46073-46078
-
-
Tsirigotis, M.1
Zhang, M.2
Chiu, R.K.3
Wouters, B.G.4
Gray, D.A.5
-
65
-
-
0032867676
-
The 26S proteasome: A molecular machine designed for controlled proteolysis
-
Voges D, Zwickl P, Baumeister W. 1999. The 26S proteasome: A molecular machine designed for controlled proteolysis. Annu Rev Biochem 68:1015-1068.
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 1015-1068
-
-
Voges, D.1
Zwickl, P.2
Baumeister, W.3
-
66
-
-
0037337815
-
Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases
-
Zarow C, Lyness SA, Mortimer JA, Chui HC. 2003. Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases. Arch Neurol 60:337-341.
-
(2003)
Arch Neurol
, vol.60
, pp. 337-341
-
-
Zarow, C.1
Lyness, S.A.2
Mortimer, J.A.3
Chui, H.C.4
|