Lactacystin-induced apoptosis of cultured mouse cortical neurons is associated with accumulation of PTEN in the detergent-resistant membrane fraction

Cellular and Molecular Life Sciences

Volumn 61, Issue 15, 2004, Pages 1926-1934

  Cheung, N S ^a   Choy, M S ^a   Halliwell, B ^a   Teo, T S ^a   Bay, B H ^a   Lee, A Y W ^a   Qi, R Z ^b   Koh, V H ^a   Whiteman, M ^a   Koay, E S C ^a,c   Chiu, L L ^c   Zhu, H J ^d   Wong, K P ^a   Beart, P M ^e   Cheng, H C ^e  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^c NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^d ROYAL MELBOURNE HOSPITAL   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Caspase 3; Neuronal death; Proteasome; Tumor suppressor

Indexed keywords

CASPASE 3; DETERGENT; LACTACYSTIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MOUSE; NERVE CELL CULTURE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; ANIMAL TISSUE; BIOACCUMULATION; BRAIN CELL; CELL FRACTIONATION; CELL MATURATION; DRUG MECHANISM; FETUS; IN VITRO STUDY;

ANIMALIA;

EID: 4143087008     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-004-4127-7     Document Type: Article

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