-
1
-
-
0028884033
-
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995;270:27489-94
-
(1995)
J Biol Chem
, vol.270
, pp. 27489-27494
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
2
-
-
34247490197
-
Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons
-
Alvira D, Tajes M, Verdaguer E, de Arriba SG, Allgaier C, Matute C, et al. Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons. Neuroscience 2007;146:350-65.
-
(2007)
Neuroscience
, vol.146
, pp. 350-365
-
-
Alvira, D.1
Tajes, M.2
Verdaguer, E.3
de Arriba, S.G.4
Allgaier, C.5
Matute, C.6
-
4
-
-
70449394392
-
Hepatitis B virus X protein (HBx) induces G2/M arrest and apoptosis through sustained activation of cyclin B1-CDK1 kinase
-
Cheng P, Li Y, Yang L, Wen Y, Shi W, Mao Y, et al. Hepatitis B virus X protein (HBx) induces G2/M arrest and apoptosis through sustained activation of cyclin B1-CDK1 kinase. Oncol Rep 2009;22:1101-7.
-
(2009)
Oncol Rep
, vol.22
, pp. 1101-1107
-
-
Cheng, P.1
Li, Y.2
Yang, L.3
Wen, Y.4
Shi, W.5
Mao, Y.6
-
5
-
-
2942517676
-
Oxidative neuronal injury The dark side of ERK1/2
-
Chu CT, Levinthal DJ, Kulich SM, Chalovich EM, DeFranco DB. Oxidative neuronal injury. The dark side of ERK1/2. Eur J Biochem 2004;271:2060-6.
-
(2004)
Eur J Biochem
, vol.271
, pp. 2060-2066
-
-
Chu, C.T.1
Levinthal, D.J.2
Kulich, S.M.3
Chalovich, E.M.4
DeFranco, D.B.5
-
6
-
-
0141741347
-
Parkinson's disease: mechanisms and models
-
Dauer W, Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003;39:889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
7
-
-
15644363581
-
Mechanistic studies on the inactivation of the proteasome by lactacystin in cultured cells
-
Dick LR, Cruikshank AA, Destree AT, Grenier L, McCormack TA, Melandri FD, et al. Mechanistic studies on the inactivation of the proteasome by lactacystin in cultured cells. J Biol Chem 1997;272:182-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 182-188
-
-
Dick, L.R.1
Cruikshank, A.A.2
Destree, A.T.3
Grenier, L.4
McCormack, T.A.5
Melandri, F.D.6
-
8
-
-
0141753018
-
Fine structure and biochemical mechanisms underlying nigrostriatal inclusions and cell death after proteasome inhibition
-
Fornai F, Lenzi P, Gesi M, Ferrucci M, Lazzeri G, Busceti CL, et al. Fine structure and biochemical mechanisms underlying nigrostriatal inclusions and cell death after proteasome inhibition. J Neurosci 2003;23:8955-66.
-
(2003)
J Neurosci
, vol.23
, pp. 8955-8966
-
-
Fornai, F.1
Lenzi, P.2
Gesi, M.3
Ferrucci, M.4
Lazzeri, G.5
Busceti, C.L.6
-
9
-
-
0026545073
-
Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells
-
Gallant P, Nigg EA. Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. J Cell Biol 1992;117:213-24.
-
(1992)
J Cell Biol
, vol.117
, pp. 213-224
-
-
Gallant, P.1
Nigg, E.A.2
-
10
-
-
0345704610
-
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
-
Greene LA, Tischler AS. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 1976;73:2424-8.
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, pp. 2424-2428
-
-
Greene, L.A.1
Tischler, A.S.2
-
11
-
-
0033961816
-
Delayed and sustained activation of p42/p44 mitogen-activated protein kinase induced by proteasome inhibitors through p21(ras) in PC12 cells
-
Hashimoto K, Guroff G, Katagiri Y. Delayed and sustained activation of p42/p44 mitogen-activated protein kinase induced by proteasome inhibitors through p21(ras) in PC12 cells. J Neurochem 2000;74:92-8.
-
(2000)
J Neurochem
, vol.74
, pp. 92-98
-
-
Hashimoto, K.1
Guroff, G.2
Katagiri, Y.3
-
12
-
-
7044237034
-
Divide and die: cell cycle events as triggers of nerve cell death
-
Herrup K, Neve R, Ackerman SL, Copani A. Divide and die: cell cycle events as triggers of nerve cell death. J Neurosci 2004;24:9232-9.
-
(2004)
J Neurosci
, vol.24
, pp. 9232-9239
-
-
Herrup, K.1
Neve, R.2
Ackerman, S.L.3
Copani, A.4
-
13
-
-
33847610595
-
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease
-
Höglinger GU, Breunig JJ, Depboylu C, Rouaux C, Michel PP, Alvarez-Fischer D, et al. The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease. Proc Natl Acad Sci USA 2007;104:3585-90.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 3585-3590
-
-
Höglinger, G.U.1
Breunig, J.J.2
Depboylu, C.3
Rouaux, C.4
Michel, P.P.5
Alvarez-Fischer, D.6
-
14
-
-
0041430614
-
Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease
-
Höglinger GU, Carrard G, Michel PP, Medja F, Lombe' s A, Ruberg M, et al. Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease. J Neurochem 2003;86:1297-307.
-
(2003)
J Neurochem
, vol.86
, pp. 1297-1307
-
-
Höglinger, G.U.1
Carrard, G.2
Michel, P.P.3
Medja, F.4
Lombe' s, A.5
Ruberg, M.6
-
15
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998;392:605-8.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
-
16
-
-
0032585351
-
Intron-exon structure of ubiquitin c-terminal hydrolase-L1
-
Leroy E, Boyer R, Polymeropoulos MH. Intron-exon structure of ubiquitin c-terminal hydrolase-L1. DNA Res 1998;5:397-400
-
(1998)
DNA Res
, vol.5
, pp. 397-400
-
-
Leroy, E.1
Boyer, R.2
Polymeropoulos, M.H.3
-
17
-
-
34147101621
-
The etiopathogenesis of Parkinson disease and suggestions for future research. Part I
-
Litvan I, Halliday G, Hallett M, Goetz CG, Rocca W, Duyckaerts C, et al. The etiopathogenesis of Parkinson disease and suggestions for future research. Part I. J Neuropathol Exp Neurol 2007;66:251-7.
-
(2007)
J Neuropathol Exp Neurol
, vol.66
, pp. 251-257
-
-
Litvan, I.1
Halliday, G.2
Hallett, M.3
Goetz, C.G.4
Rocca, W.5
Duyckaerts, C.6
-
18
-
-
27144526198
-
Mitogen-activated protein kinases in cell-cycle control
-
MacCorkle RA, Tan TH. Mitogen-activated protein kinases in cell-cycle control. Cell Biochem Biophys 2005;43:451-61.
-
(2005)
Cell Biochem Biophys
, vol.43
, pp. 451-461
-
-
MacCorkle, R.A.1
Tan, T.H.2
-
19
-
-
0037227397
-
Altered proteasomal function in sporadic Parkinson's disease
-
McNaught KS, Belizaire R, Isacson O, Jenner P, Olanow CW. Altered proteasomal function in sporadic Parkinson's disease. Exp Neurol 2003;179:38-46.
-
(2003)
Exp Neurol
, vol.179
, pp. 38-46
-
-
McNaught, K.S.1
Belizaire, R.2
Isacson, O.3
Jenner, P.4
Olanow, C.W.5
-
20
-
-
0035910634
-
Proteasomal function is impaired in substantia nigra in Parkinson's disease
-
McNaught KS, Jenner P. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett 2001;297:191-4.
-
(2001)
Neurosci Lett
, vol.297
, pp. 191-194
-
-
McNaught, K.S.1
Jenner, P.2
-
21
-
-
0036316947
-
Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures
-
McNaught KS, Mytilineou C, Jnobaptiste R, Yabut J, Shashidharan P, Jennert P, et al. Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures. J Neurochem 2002;81:301-6.
-
(2002)
J Neurochem
, vol.81
, pp. 301-306
-
-
McNaught, K.S.1
Mytilineou, C.2
Jnobaptiste, R.3
Yabut, J.4
Shashidharan, P.5
Jennert, P.6
-
22
-
-
34248563290
-
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
-
Meloche S, Pouysségur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007;26:3227-39.
-
(2007)
Oncogene
, vol.26
, pp. 3227-3239
-
-
Meloche, S.1
Pouysségur, J.2
-
23
-
-
34347351340
-
Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease
-
Mosch B, Morawski M, Mittag A, Lenz D, Tarnok A, Arendt T. Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease. J Neurosci 2007;27:6859-67.
-
(2007)
J Neurosci
, vol.27
, pp. 6859-6867
-
-
Mosch, B.1
Morawski, M.2
Mittag, A.3
Lenz, D.4
Tarnok, A.5
Arendt, T.6
-
24
-
-
7944226117
-
Inhibition of proteasome activity sensitizes dopamine neurons to protein alterations and oxidative stress
-
Mytilineou C, McNaught KS, Shashidharan P, Yabut J, Baptiste RJ, Parnandi A, et al. Inhibition of proteasome activity sensitizes dopamine neurons to protein alterations and oxidative stress. J Neural Transm 2004;111:1237-51.
-
(2004)
J Neural Transm
, vol.111
, pp. 1237-1251
-
-
Mytilineou, C.1
McNaught, K.S.2
Shashidharan, P.3
Yabut, J.4
Baptiste, R.J.5
Parnandi, A.6
-
25
-
-
33646345376
-
Ubiquitin ligases: cell-cycle control and cancer
-
Nakayama KI, Nakayama K. Ubiquitin ligases: cell-cycle control and cancer. Nat Rev Cancer 2006;6:369-81.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 369-381
-
-
Nakayama, K.I.1
Nakayama, K.2
-
26
-
-
36248938279
-
The pathogenesis of cell death in Parkinson's disease-2007
-
Olanow CW. The pathogenesis of cell death in Parkinson's disease-2007. Mov Disord 2007;22:S335-42.
-
(2007)
Mov Disord
, vol.22
-
-
Olanow, C.W.1
-
27
-
-
54049120956
-
E2F-at the crossroads of life and death
-
Polager S, Ginsberg D. E2F-at the crossroads of life and death. Trends Cell Biol 2008;18:528-35.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 528-535
-
-
Polager, S.1
Ginsberg, D.2
-
28
-
-
0037372292
-
Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis
-
Ranganathan S, Bowser R. Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis. Am J Pathol 2003;162:823-35.
-
(2003)
Am J Pathol
, vol.162
, pp. 823-835
-
-
Ranganathan, S.1
Bowser, R.2
-
29
-
-
33744982893
-
Etiology of Parkinson's disease
-
Schapira AH. Etiology of Parkinson's disease. Neurology 2006;66:S10-23.
-
(2006)
Neurology
, vol.66
-
-
Schapira, A.H.1
-
30
-
-
51649116692
-
Update on the pathogenesis of Parkinson's disease
-
Schulz JB. Update on the pathogenesis of Parkinson's disease. J Neurol 2008;255:3-7.
-
(2008)
J Neurol
, vol.255
, pp. 3-7
-
-
Schulz, J.B.1
-
31
-
-
33750370804
-
Understanding the molecular causes of Parkinson's disease
-
Wood-Kaczmar A, Gandhi S, Wood NW. Understanding the molecular causes of Parkinson's disease. Trends Mol Med 2006;12:521-8.
-
(2006)
Trends Mol Med
, vol.12
, pp. 521-528
-
-
Wood-Kaczmar, A.1
Gandhi, S.2
Wood, N.W.3
-
32
-
-
33947289969
-
Cell division in the CNS: protective response or lethal event in post-mitotic neurons?
-
Yang Y, Herrup K. Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim Biophys Acta 2007;1772:457-66.
-
(2007)
Biochim Biophys Acta
, vol.1772
, pp. 457-466
-
-
Yang, Y.1
Herrup, K.2
-
33
-
-
0035871660
-
DNA replication precedes neuronal cell death in Alzheimer's disease
-
Yang Y, Geldmacher DS, Herrup K. DNA replication precedes neuronal cell death in Alzheimer's disease. J Neurosci 2001;21:2661-8.
-
(2001)
J Neurosci
, vol.21
, pp. 2661-2668
-
-
Yang, Y.1
Geldmacher, D.S.2
Herrup, K.3
-
34
-
-
0344241479
-
Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease
-
Yang Y, Mufson EJ, Herrup K. Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease. J Neurosci 2003;23:2557-63.
-
(2003)
J Neurosci
, vol.23
, pp. 2557-2563
-
-
Yang, Y.1
Mufson, E.J.2
Herrup, K.3
-
35
-
-
0034011955
-
Cell cycle regulators in neural stem cells and postmitotic neurons
-
Yoshikawa K. Cell cycle regulators in neural stem cells and postmitotic neurons. Neurosci Res 2000;37:1-14.
-
(2000)
Neurosci Res
, vol.37
, pp. 1-14
-
-
Yoshikawa, K.1
-
36
-
-
0242499488
-
Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases
-
Zhu JH, Guo F, Shelburne J, Watkins S, Chu CT. Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases. Brain Pathol 2003;13:473-81.
-
(2003)
Brain Pathol
, vol.13
, pp. 473-481
-
-
Zhu, J.H.1
Guo, F.2
Shelburne, J.3
Watkins, S.4
Chu, C.T.5
|