-
1
-
-
43549101974
-
The integrative role of CNS fuel-sensing mechanisms in energy balance and glucose regulation
-
DOI 10.1146/annurev.physiol.70.120806.095256
-
Sandoval D, Cota D, Seeley RJ. The integrative role of CNS fuel-sensing mechanisms in energy balance and glucose regulation. Annu Rev Physiol. 2008;70:513-35. doi:10.1146/ annurev.physiol.70.120806.095256. (Pubitemid 351738190)
-
(2008)
Annual Review of Physiology
, vol.70
, pp. 513-535
-
-
Sandoval, D.1
Cota, D.2
Seeley, R.J.3
-
2
-
-
77649226732
-
Overview of the physiological control of eating
-
Langhans W, Geary N. Overview of the physiological control of eating. Forum Nutr. 2010;63:9-53.
-
(2010)
Forum Nutr
, vol.63
, pp. 9-53
-
-
Langhans, W.1
Geary, N.2
-
3
-
-
0034704731
-
A prospective study of holiday weight gain
-
DOI 10.1056/NEJM200003233421206
-
Yanovski JA, Yanovski SZ, Sovik KN, Nguyen TT, O'Neil PM, Sebring NG. A prospective study of holiday weight gain. N Engl J Med. 2000;342(12):861-7. doi:10.1056/NEJM200003233421206. (Pubitemid 30165210)
-
(2000)
New England Journal of Medicine
, vol.342
, Issue.12
, pp. 861-867
-
-
Yanovski, J.A.1
Yanovski, S.Z.2
Sovik, K.N.3
Nguyen, T.T.4
O'Neil, P.M.5
Sebring, N.G.6
-
4
-
-
0023829632
-
Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects
-
Polonsky KS, Given BD, Van Cauter E. Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. J Clin Invest. 1988;81(2):442-8. doi:10.1172/JCI113339. (Pubitemid 18075238)
-
(1988)
Journal of Clinical Investigation
, vol.81
, Issue.2
, pp. 442-448
-
-
Polonsky, K.S.1
Given, B.D.2
Van Cauter, E.3
-
5
-
-
0025063027
-
Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid
-
Schwartz MW, Sipols A, Kahn SE, Lattemann DF, Taborsky Jr GJ, Bergman RN, et al. Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. Am J Physiol. 1990;259(3 Pt 1):E378-83. (Pubitemid 20320760)
-
(1990)
American Journal of Physiology - Endocrinology and Metabolism
, vol.259
, Issue.3
-
-
Schwartz, M.W.1
Sipols, A.2
Kahn, S.E.3
Lattemann, D.F.4
Taborsky Jr., G.J.5
Bergman, R.N.6
Woods, S.C.7
Porte Jr., D.8
-
6
-
-
0020562895
-
Immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid
-
Baskin DG, Woods SC, West DB, van Houten M, Posner BI, Dorsa DM, et al. Immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid. Endocrinology. 1983;113(5):1818-25. (Pubitemid 13023826)
-
(1983)
Endocrinology
, vol.113
, Issue.5
, pp. 1818-1825
-
-
Baskin, D.G.1
Woods, S.C.2
West, D.B.3
-
7
-
-
0028348778
-
Insulin receptor substrate-1 (IRS-1) expression in rat brain
-
DOI 10.1210/en.134.4.1952
-
Baskin DG, Schwartz MW, Sipols AJ, DAlessio DA, Goldstein BJ, White MF. Insulin receptor substrate-1 (IRS-1) expression in rat brain. Endocrinology 1994;134(4):1952-5. (Pubitemid 24110760)
-
(1994)
Endocrinology
, vol.134
, Issue.4
, pp. 1952-1955
-
-
Baskin, D.G.1
Schwartz, M.W.2
Sipols, A.J.3
D'Alessio, D.A.4
Goldstein, B.J.5
White, M.F.6
-
8
-
-
0036267472
-
Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats
-
DOI 10.1038/nn861
-
Obici S, Feng Z, Karkanias G, Baskin DG, Rossetti L. Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats. Nat Neurosci. 2002;5(6):566-72. doi:10.1038/nn861. (Pubitemid 34568999)
-
(2002)
Nature Neuroscience
, vol.5
, Issue.6
, pp. 566-572
-
-
Obici, S.1
Feng, Z.2
Karkanias, G.3
Baskin, D.G.4
Rossetti, L.5
-
9
-
-
0029066934
-
Intraventricular insulin and the level of maintained body weight in rats
-
Chavez M, Kaiyala K, Madden LJ, Schwartz MW, Woods SC. Intraventricular insulin and the level of maintained body weight in rats. Behav Neurosci. 1995;109(3):528-31.
-
(1995)
Behav Neurosci
, vol.109
, Issue.3
, pp. 528-31
-
-
Chavez, M.1
Kaiyala, K.2
Madden, L.J.3
Schwartz, M.W.4
Woods, S.C.5
-
10
-
-
0034703229
-
Role of brain insulin receptor in control ofbody weight and reproduction
-
Bruning JC, Gautam D, Burks DJ, Gillette J, Schubert M, Orban PC, et al. Role of brain insulin receptor in control ofbody weight and reproduction. Science. 2000;289(5487):2122-5.
-
(2000)
Science
, vol.289
, Issue.5487
, pp. 2122-5
-
-
Bruning, J.C.1
Gautam, D.2
Burks, D.J.3
Gillette, J.4
Schubert, M.5
Orban, P.C.6
-
11
-
-
0036202441
-
Acute third ventricular administration of insulin decreases food intake in two paradigms
-
DOI 10.1016/S0091-3057(01)00780-8, PII S0091305701007808
-
Air EL, Benoit SC, Blake Smith KA, Clegg DJ, Woods SC. Acute third ventricular administration of insulin decreases food intake in two paradigms. Pharmacol Biochem Behav. 2002;72(1-2):423-9. (Pubitemid 34251354)
-
(2002)
Pharmacology Biochemistry and Behavior
, vol.72
, Issue.1-2
, pp. 423-429
-
-
Air, E.L.1
Benoit, S.C.2
Blake Smith, K.A.3
Clegg, D.J.4
Woods, S.C.5
-
12
-
-
0018621289
-
Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons
-
Woods SC, Lotter EC, Mc Kay LD, Porte Jr D. Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature. 1979;282(5738):503-5. (Pubitemid 10126541)
-
(1979)
Nature
, vol.282
, Issue.5738
, pp. 503-505
-
-
Woods, S.C.1
Lotter, E.C.2
McKay, L.D.3
Porte Jr., D.4
-
13
-
-
0029001647
-
Intraventricular insulin enhances the meal-suppressive efficacy of intraventricular cholecystokinin octapeptide in the baboon
-
Figlewicz DP, Sipols AJ, Seeley RJ, Chavez M, Woods SC, Porte Jr D. Intraventricular insulin enhances the meal-suppressive efficacy of intraventricular cholecystokinin octapeptide in the baboon. Behav Neurosci. 1995;109(3):567-9.
-
(1995)
Behav Neurosci
, vol.109
, Issue.3
, pp. 567-9
-
-
Figlewicz, D.P.1
Sipols, A.J.2
Seeley, R.J.3
Chavez, M.4
Woods, S.C.5
Porte Jr., D.6
-
14
-
-
0344406153
-
Differential sensitivity to central leptin and insulin in male and female rats
-
DOI 10.2337/diabetes.52.3.682
-
Clegg DJ, Riedy CA, Smith KA, Benoit SC, Woods SC Differential sensitivity to central leptin and insulin in male and female rats. Diabetes. 2003;52(3):682-7. (Pubitemid 36323575)
-
(2003)
Diabetes
, vol.52
, Issue.3
, pp. 682-687
-
-
Clegg, D.J.1
Riedy, C.A.2
Smith, K.A.B.3
Benoit, S.C.4
Woods, S.C.5
-
15
-
-
33745298324
-
Gonadal hormones determine sensitivity to central leptin and insulin
-
DOI 10.2337/diabetes.55.04.06.db05-1339
-
Clegg DJ, Brown LM, Woods SC, Benoit SC Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes. 2006;55(4):978-87. (Pubitemid 44100172)
-
(2006)
Diabetes
, vol.55
, Issue.4
, pp. 978-987
-
-
Clegg, D.J.1
Brown, L.M.2
Woods, S.C.3
Benoit, S.C.4
-
16
-
-
0037315042
-
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key mediator of insulin-induced anorexia
-
DOI 10.2337/diabetes.52.2.227
-
Niswender KD, Morrison CD, Clegg DJ, Olson R, Baskin DG, Myers Jr MG, et al. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes. 2003;52(2):227-31. (Pubitemid 36173172)
-
(2003)
Diabetes
, vol.52
, Issue.2
, pp. 227-231
-
-
Niswender, K.D.1
Morrison, C.D.2
Clegg, D.J.3
Olson, R.4
Baskin, D.G.5
Myers Jr., M.G.6
Seeley, R.J.7
Schwartz, M.W.8
-
17
-
-
33745819212
-
ATP channel activation and leads to diet-sensitive obesity
-
DOI 10.1172/JCI27123
-
Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Munzberg H, et al. Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity J Clin Invest. 2006;116(7):1886-901. doi:10.1172/JCI27123. (Pubitemid 44033313)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1886-1901
-
-
Plum, L.1
Ma, X.2
Hampel, B.3
Balthasar, N.4
Coppari, R.5
Munzberg, H.6
Shanabrough, M.7
Burdakov, D.8
Rother, E.9
Janoschek, R.10
Alber, J.11
Belgardt, B.F.12
Koch, L.13
Seibler, J.14
Schwenk, F.15
Fekete, C.16
Suzuki, A.17
Mak, T.W.18
Krone, W.19
Horvath, T.L.20
Ashcroft, F.M.21
Bruning, J.C.22
more..
-
18
-
-
0026710057
-
Inhibition ofhypothalamic neuropeptide y gene expressionbyinsulin
-
Schwartz MW, Sipols AJ, Marks JL, Sanacora G, White JD, Scheurink A, et al. Inhibition ofhypothalamic neuropeptide Y gene expressionbyinsulin. Endocrinology. 1992;130(6):3608-16.
-
(1992)
Endocrinology
, vol.130
, Issue.6
, pp. 3608-16
-
-
Schwartz, M.W.1
Sipols, A.J.2
Marks, J.L.3
Sanacora, G.4
White, J.D.5
Scheurink, A.6
-
19
-
-
79952484959
-
Consumption of a high-fat diet induces central insulin resistance independent ofadiposity
-
Clegg DJ, Gotoh K, Kemp C, Wortman MD, Benoit SC, Brown LM et al. Consumption of a high-fat diet induces central insulin resistance independent ofadiposity. Physiol Behav. 2011.
-
(2011)
Physiol Behav
-
-
Clegg, D.J.1
Gotoh, K.2
Kemp, C.3
Wortman, M.D.4
Benoit, S.C.5
Brown, L.M.6
-
20
-
-
15544374102
-
Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet
-
DOI 10.1152/ajpregu.00675.2004
-
Clegg DJ, Benoit SC, Reed JA, Woods SC, Dunn-Meynell A, Levin BE. Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet. Am J Physiol Regul Integr Comp Physiol. 2005;288(4):R981-6. (Pubitemid 40404173)
-
(2005)
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
, vol.288
, Issue.4
-
-
Clegg, D.J.1
Benoit, S.C.2
Reed, J.A.3
Woods, S.C.4
Dunn-Meynell, A.5
Levin, B.E.6
-
21
-
-
0025804616
-
Central insulin administration reduces neuro-peptide y m RNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) Zucker rats
-
Schwartz MW, Marks JL, Sipols AJ, Baskin DG, Woods SC, Kahn SE, et al. Central insulin administration reduces neuro-peptide Y m RNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) Zucker rats. Endocrinology 1991;128(5):2645-7.
-
(1991)
Endocrinology
, vol.128
, Issue.5
, pp. 2645-7
-
-
Schwartz, M.W.1
Marks, J.L.2
Sipols, A.J.3
Baskin, D.G.4
Woods, S.C.5
Kahn, S.E.6
-
22
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
DOI 10.1056/NEJM199602013340503
-
Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, et al. Serum immunoreactive-leptin concentra-tions in normal-weight and obese humans. N Engl J Med. 1996;334(5):292-5. (Pubitemid 26033933)
-
(1996)
New England Journal of Medicine
, vol.334
, Issue.5
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
Nyce, M.R.6
Ohannesian, J.P.7
Marco, C.C.8
Mckee, L.J.9
Bauer, T.L.10
Caro, J.F.11
-
23
-
-
0029739970
-
Identification of targets of leptin action in rat hypothalamus
-
Schwartz MW, Seeley RJ, Campfield LA, Burn P, Baskin DG. Identification of targets of leptin action in rat hypothalamus. J Clin Invest. 1996;98(5):1101-6. doi:10.1172/JCI118891. (Pubitemid 26299921)
-
(1996)
Journal of Clinical Investigation
, vol.98
, Issue.5
, pp. 1101-1106
-
-
Schwartz, M.W.1
Seeley, R.J.2
Campfield, L.A.3
Burn, P.4
Baskin, D.G.5
-
25
-
-
0016599197
-
Hepatic metabolism of genetically diabetic (db/db) mice. I. Carbohydrate metabolism
-
Chan TM, Young KM, Hutson NJ, Brumley FT, Exton JH. Hepatic metabolism of genetically diabetic (db/db) mice. I. Carbohydrate metabolism. Am J Physiol. 1975;229(6):1702-12.
-
(1975)
Am J Physiol
, vol.229
, Issue.6
, pp. 1702-12
-
-
Chan, T.M.1
Young, K.M.2
Hutson, N.J.3
Brumley, F.T.4
Exton, J.H.5
-
26
-
-
0013638175
-
Genetic factors in obesity
-
Mayer J. Genetic factors in obesity. Bull N YAcad Med. 1960;36 (5):323-43.
-
(1960)
Bull N YAcad Med
, vol.36
, Issue.5
, pp. 323-43
-
-
Mayer, J.1
-
27
-
-
0037733115
-
k) rats
-
DOI 10.1210/en.2002-0115
-
Morton GJ, Niswender KD, Rhodes CJ, Myers Jr MG, Blevins JE, Baskin DG, et al. Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/ fa(k)) rats. Endocrinology 2003;144(5):2016-24. (Pubitemid 36543342)
-
(2003)
Endocrinology
, vol.144
, Issue.5
, pp. 2016-2024
-
-
Morton, G.J.1
Niswender, K.D.2
Rhodes, C.J.3
Myers Jr., M.G.4
Blevins, J.E.5
Baskin, D.G.6
Schwartz, M.W.7
-
28
-
-
0007500186
-
Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats
-
Seeley RJ, van Dijk G, Campfield LA, Smith FJ, Burn P Nelligan JA, et al. Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats. Horm Metab Res. 1996;28(12):664-8. doi:10.1055/s-2007- 979874. (Pubitemid 27057912)
-
(1996)
Hormone and Metabolic Research
, vol.28
, Issue.12
, pp. 664-668
-
-
Seeley, R.J.1
Van Dijk, G.2
Campfield, L.A.3
Smith, F.J.4
Burn, P.5
Nelligan, J.A.6
Bell, S.M.7
Baskin, D.G.8
Woods, S.C.9
Schwartz, M.W.10
-
29
-
-
0031226662
-
Effects of intracerebroventricular infusion of leptin in obese zucker rats
-
Al-Barazanji KA, Buckingham RE, Arch JR, Haynes A, Mossakowska DE, Mc Bay DL, et al. Effects of intracerebroven-tricular infusion of leptin in obese Zucker rats. Obes Res. 1997;5 (5):387-94. (Pubitemid 127702691)
-
(1997)
Obesity Research
, vol.5
, Issue.5
, pp. 387-394
-
-
Al-Barazanji, K.A.1
Buckingham, R.E.2
Arch, J.R.S.3
Haynes, A.4
Mossakowska, D.E.5
McBay, D.L.6
Holmes, S.D.7
McHale, M.T.8
Wang, X.-M.9
Gloger, I.S.10
-
30
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz MW, Woods SC, Porte Jr D, Seeley RJ, Baskin DG. Central nervous system control of food intake. Nature. 2000;404 (6778):661-71. doi:10.1038/35007534. (Pubitemid 30205071)
-
(2000)
Nature
, vol.404
, Issue.6778
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte Jr., D.3
Seeley, R.J.4
Baskin, D.G.5
-
31
-
-
33745362866
-
Critical role of STAT3 in leptin's metabolic actions
-
DOI 10.1016/j.cmet.2006.04.014, PII S1550413106001549
-
Buettner C, Pocai A, Muse ED, Etgen AM, Myers Jr MG, Rossetti L. Critical role of STAT3 in leptin's metabolic actions. Cell Metab. 2006;4(1):49-60. (Pubitemid 43942253)
-
(2006)
Cell Metabolism
, vol.4
, Issue.1
, pp. 49-60
-
-
Buettner, C.1
Pocai, A.2
Muse, E.D.3
Etgen, A.M.4
Myers Jr., M.G.5
Rossetti, L.6
-
32
-
-
1842584949
-
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
-
DOI 10.1073/pnas.0303992101
-
Gao Q, Wolfgang MJ, Neschen S, Morino K, Horvath TL, Shulman GI, et al. Disruption of neural signal transducer and activator of transcription 3 causes obesity diabetes, infertility, and thermal dysregulation. Proc Natl Acad Sci USA. 2004;101 (13):4661-6. doi:10.1073/pnas.0303992101. (Pubitemid 38437467)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.13
, pp. 4661-4666
-
-
Gao, Q.1
Wolfgang, M.J.2
Neschen, S.3
Morino, K.4
Horvath, T.L.5
Shulman, G.I.6
Fu, X.-Y.7
-
33
-
-
0035950093
-
Intracellular signalling: Key enzyme in leptin-induced anorexia
-
Niswender KD, Morton GJ, Stearns WH, Rhodes CJ, Myers Jr MG, Schwartz MW. Intracellular signalling. Key enzyme in leptin-induced anorexia. Nature. 2001;413(6858):794-5. doi:10.1038/35101657. (Pubitemid 33026839)
-
(2001)
Nature
, vol.413
, Issue.6858
, pp. 794-795
-
-
Niswender, K.D.1
Morton, G.J.2
Stearns, W.H.3
Rhodes, C.J.4
Myers Jr., M.G.5
Schwartz, M.W.6
-
34
-
-
30044447631
-
Schwartz MW Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypo-thalamic neurons
-
Morton GJ, Gelling RW, Niswender KD, Morrison CD, Rhodes CJ, Schwartz MW Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypo-thalamic neurons. Cell Metab. 2005;2(6):411-20.
-
(2005)
Cell Metab
, vol.2
, Issue.6
, pp. 411-20
-
-
Morton, G.J.1
Gelling, R.W.2
Niswender, K.D.3
Morrison, C.D.4
Rhodes, C.J.5
-
35
-
-
33646582664
-
Hypothalamic mTOR signaling regulates food intake
-
DOI 10.1126/science.1124147
-
Cota D, Proulx K, Smith KA, Kozma SC, Thomas G, Woods SC, et al. Hypothalamic m TOR signaling regulates food intake. Science. 2006;312(5775):927-30. (Pubitemid 43727328)
-
(2006)
Science
, vol.312
, Issue.5775
, pp. 927-930
-
-
Cota, D.1
Proulx, K.2
Blake Smith, K.A.3
Kozma, S.C.4
Thomas, G.5
Woods, S.C.6
Seeley, R.J.7
-
36
-
-
0031748933
-
Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins
-
DOI 10.2337/diabetes.47.7.1014
-
Cusin I, Zakrzewska KE, Boss O, Muzzin P, Giacobino JP Ricquier D, et al. Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression ofuncouplingproteins. Diabetes. 1998;47(7):1014-9. (Pubitemid 28294541)
-
(1998)
Diabetes
, vol.47
, Issue.7
, pp. 1014-1019
-
-
Cusin, I.1
Zakrzewska, K.E.2
Boss, O.3
Muzzin, P.4
Giacobino, J.-P.5
Ricquier, D.6
Jeanrenaud, B.7
Rohner-Jeanrenaud, F.8
-
37
-
-
0030669288
-
Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity
-
Widdowson PS, Upton R, Buckingham R, Arch J, Williams G. Inhibition offood response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity Diabetes. 1997;46(11):1782-5. (Pubitemid 27456411)
-
(1997)
Diabetes
, vol.46
, Issue.11
, pp. 1782-1785
-
-
Widdowson, P.S.1
Upton, R.2
Buckingham, R.3
Arch, J.4
Williams, G.5
-
38
-
-
49049114337
-
Therole ofhypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity
-
Cota D,Matter EK,Woods SC, Seeley RJ. Therole ofhypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity J Neurosci. 2008;28(28):7202-8.
-
(2008)
J Neurosci
, vol.28
, Issue.28
, pp. 7202-8
-
-
Cota, D.1
Matter, E.K.2
Woods, S.C.3
Seeley, R.J.4
-
39
-
-
40849083773
-
Hypothalamic phosphatidylinositol 3-kinase pathway of leptin signaling is impaired during the development of diet-induced obesity in FVB/N mice
-
DOI 10.1210/en.2007-1307
-
Metlakunta AS, Sahu M, Sahu A. Hypothalamic phosphatidyli-nositol 3-kinase pathway of leptin signaling is impaired during the development of diet-induced obesity in FVB/N mice. Endocrinology 2008;149(3):1121-8. (Pubitemid 351397951)
-
(2008)
Endocrinology
, vol.149
, Issue.3
, pp. 1121-1128
-
-
Metlakunta, A.S.1
Sahu, M.2
Sahu, A.3
-
40
-
-
9244219587
-
Region-specific leptin resistance within the hypothalamus of diet-induced obese mice
-
DOI 10.1210/en.2004-0726
-
Munzberg H, Flier JS, Bjorbaek C. Region-specific leptin resistance within the hypothalamus of diet-induced obese mice. Endocrinology 2004;145(11):4880-9. doi:10.1210/en.2004-0726. (Pubitemid 39551104)
-
(2004)
Endocrinology
, vol.145
, Issue.11
, pp. 4880-4889
-
-
Munzberg, H.1
Flier, J.S.2
Bjorbaek, C.3
-
41
-
-
0014683812
-
Glucose and osmosensitive neurones of the rat hypothalamus
-
Oomura Y Ono T, Ooyama H, Wayner MJ. Glucose and osmosensitive neurones of the rat hypothalamus. Nature. 1969;222(5190):282-4.
-
(1969)
Nature
, vol.222
, Issue.5190
, pp. 282-4
-
-
Oomura Ono, Y.T.1
Ooyama, H.2
Wayner, M.J.3
-
42
-
-
0001643038
-
Activity of single neurons in the hypothalamic feeding centers: Effect of glucose
-
Anand BK, Chhina GS, Sharma KN, Dua S, Singh B. Activity of single neurons in the hypothalamic feeding centers: effect of glucose. Am J Physiol. 1964;207:1146-54.
-
(1964)
Am J Physiol
, vol.207
, pp. 1146-54
-
-
Anand, B.K.1
Chhina, G.S.2
Sharma, K.N.3
Dua, S.4
Singh, B.5
-
44
-
-
0037387207
-
ATP channels
-
DOI 10.1210/en.2002-221033
-
Ibrahim N, Bosch MA, Smart JL, Qiu J, Rubinstein M, Ronnekleiv OK, et al. Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels. Endocrinology. 2003;144(4):1331-40. (Pubitemid 36428475)
-
(2003)
Endocrinology
, vol.144
, Issue.4
, pp. 1331-1340
-
-
Ibrahim, N.1
Bosch, M.A.2
Smart, J.L.3
Qiu, J.4
Rubinstein, M.5
Ronnekleiv, O.K.6
Low, M.J.7
Kelly, M.J.8
-
45
-
-
0033515710
-
Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y
-
DOI 10.1016/S0304-3940(99)00185-8, PII S0304394099001858
-
Muroya S, Yada T, Shioda S, Takigawa M. Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y Neurosci Lett. 1999;264(1-3):113-6. (Pubitemid 29195962)
-
(1999)
Neuroscience Letters
, vol.264
, Issue.1-3
, pp. 113-116
-
-
Muroya, S.1
Yada, T.2
Shioda, S.3
Takigawa, M.4
-
46
-
-
33845945261
-
Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity
-
DOI 10.1007/s00125-006-0473-3
-
Mountjoy PD, Bailey SJ, Rutter GA. Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity. Diabetologia. 2007;50(1):168-77. doi:10.1007/s00125- 006-0473-3. (Pubitemid 46035865)
-
(2007)
Diabetologia
, vol.50
, Issue.1
, pp. 168-177
-
-
Mountjoy, P.D.1
Bailey, S.J.2
Rutter, G.A.3
-
47
-
-
34248204584
-
Characterization of glucosensing neuron subpopulations in the arcuate nucleus: Integration in neuropeptide y and pro-opio melanocortin networks?
-
DOI 10.2337/db06-0567
-
Fioramonti X, Contie S, Song Z, Routh VH, Lorsignol A, Penicaud L. Characterization of glucosensing neuron subpopu-lations in the arcuate nucleus: integration in neuropeptide Yand pro-opio melanocortin networks? Diabetes. 2007;56(5):1219-27. (Pubitemid 46715601)
-
(2007)
Diabetes
, vol.56
, Issue.5
, pp. 1219-1227
-
-
Fioramonti, X.1
Contie, S.2
Song, Z.3
Routh, V.H.4
Lorsignol, A.5
Penicaud, L.6
-
48
-
-
0019505898
-
Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats
-
Davis JD, Wirtshafter D, Asin KE, Brief D. Sustained intra- cerebroventricular infusion of brain fuels reduces body weight and food intake in rats. Science. 1981;212(4490):81-3. (Pubitemid 11114689)
-
(1981)
Science
, vol.212
, Issue.4490
, pp. 81-83
-
-
Davis, J.D.1
Wirtshafter, D.2
Asin, K.E.3
Brief, D.4
-
49
-
-
0019511895
-
D-glucose infusions into the basal ventromedial hypothalamus and feeding
-
DOI 10.1016/0166-4328(81)90006-1
-
Panksepp J, Rossi 3rd J. D-glucose infusions into the basal ventromedial hypothalamus and feeding. Behav Brain Res. 1981;3(3):381-92. (Pubitemid 11020301)
-
(1981)
Behavioural Brain Research
, vol.3
, Issue.3
, pp. 381-392
-
-
Panksepp, J.1
Rossi III, J.2
-
50
-
-
0022445038
-
D-glucose suppression of eating after intra-third ventricle infusion in rat
-
DOI 10.1016/0031-9384(86)90295-7
-
Kurata K, Fujimoto K, Sakata T, Etou H, Fukagawa K. D-glucose suppression of eating after intra-third ventricle infusion in rat Physiol Behav. 1986;37(4):615-20. (Pubitemid 16056628)
-
(1986)
Physiology and Behavior
, vol.37
, Issue.4
, pp. 615-620
-
-
Kurata, K.1
Fujimoto, K.2
Sakata, T.3
-
51
-
-
4644253021
-
Neuronal glucosensing: What do we know after 50 years?
-
DOI 10.2337/diabetes.53.10.2521
-
Levin BE, Routh VH, Kang L, Sanders NM, Dunn-Meynell AA. Neuronal glucosensing: what do we know after 50 years? Diabetes. 2004;53(10):2521-8. (Pubitemid 39299257)
-
(2004)
Diabetes
, vol.53
, Issue.10
, pp. 2521-2528
-
-
Levin, B.E.1
Routh, V.H.2
Kang, L.3
Sanders, N.M.4
Dunn-Meynell, A.A.5
-
52
-
-
0016587571
-
Feeding induced by intracerebroven-tricular 2-deoxy-D-glucose in the rat
-
Miselis RR, Epstein AN. Feeding induced by intracerebroven-tricular 2-deoxy-D-glucose in the rat Am J Physiol. 1975;229 (5):1438-47.
-
(1975)
Am J Physiol
, vol.229
, Issue.5
, pp. 1438-47
-
-
Miselis, R.R.1
Epstein, A.N.2
-
53
-
-
0014593248
-
Increased feeding in response to decreased glucose utilization in the rat and monkey
-
Smith GP, Epstein AN Increased feeding in response to decreased glucose utilization in the rat and monkey. Am J Physiol. 1969;217(4):1083-7.
-
(1969)
Am J Physiol
, vol.217
, Issue.4
, pp. 1083-7
-
-
Smith, G.P.1
Epstein, A.N.2
-
54
-
-
0017531067
-
Ingestive behavior after intracere-bral and intracerebroventricular infusions of glucose and 2-deoxy-D-glucose
-
Berthoud HR, Mogenson GJ. Ingestive behavior after intracere-bral and intracerebroventricular infusions of glucose and 2-deoxy-D-glucose. Am J Physiol. 1977;233(3):R127-33.
-
(1977)
Am J Physiol
, vol.233
, Issue.3
-
-
Berthoud, H.R.1
Mogenson, G.J.2
-
55
-
-
0142067094
-
Intracerebroventricular administration of antisense oligodeoxynucleotide against GLUT2 glucose transporter mRNA reduces food intake, body weight change and glucoprivic feeding response in rats
-
Wan HZ, Hulsey MG, Martin RJ. Intracerebroventricular administration of antisense oligodeoxynucleotide against GLUT2 glucose transporter m RNA reduces food intake, body weight change and glucoprivic feeding response in rats. J Nutr 1998;128(2):287-91. (Pubitemid 28125000)
-
(1998)
Journal of Nutrition
, vol.128
, Issue.2
, pp. 287-291
-
-
Wan, H.Z.1
Hulsey, M.G.2
Martin, R.J.3
-
56
-
-
33745322219
-
Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding
-
DOI 10.2337/diabetes.55.04.06.db05-1386
-
Bady I, Marty N, Dallaporta M, Emery M, Gyger J, Tarussio D, et al. Evidence from glut2-null mice that glucose is a critical physiologicalregulatoroffeeding. Diabetes. 2006;55(4):988-95. (Pubitemid 44100173)
-
(2006)
Diabetes
, vol.55
, Issue.4
, pp. 988-995
-
-
Bady, I.1
Marty, N.2
Dallaporta, M.3
Emery, M.4
Gyger, J.5
Tarussio, D.6
Foretz, M.7
Thorens, B.8
-
57
-
-
0035042796
-
+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis
-
Miki T Liss B, Minami K, Shiuchi T, Saraya A, Kashima Y et al. ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis. Nat Neurosci. 2001;4 (5):507-12. doi:10.1038/87455. (Pubitemid 32397188)
-
(2001)
Nature Neuroscience
, vol.4
, Issue.5
, pp. 507-512
-
-
Miki, T.1
Liss, B.2
Minami, K.3
Shiuchi, T.4
Saraya, A.5
Kashima, Y.6
Horiuchi, M.7
Ashcroft, F.8
Minokoshi, Y.9
Roeper, J.10
Seino, S.11
-
58
-
-
34548604499
-
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
-
DOI 10.1038/nature06098, PII NATURE06098
-
Parton LE, Ye CP, Coppari R, Enriori PJ, Choi B, Zhang CY et al. Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity Nature. 2007;449 (7159):228-32. (Pubitemid 47402365)
-
(2007)
Nature
, vol.449
, Issue.7159
, pp. 228-232
-
-
Parton, L.E.1
Ye, C.P.2
Coppari, R.3
Enriori, P.J.4
Choi, B.5
Zhang, C.-Y.6
Xu, C.7
Vianna, C.R.8
Balthasar, N.9
Lee, C.E.10
Elmquist, J.K.11
Cowley, M.A.12
Lowell, B.B.13
-
59
-
-
34547651092
-
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
-
DOI 10.1172/JCI31516
-
Claret M, Smith MA, Batterham RL, Selman C, Choudhury AI, Fryer LG, et al. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and Ag RP neurons. J Clin Invest. 2007;117(8):2325-36. doi:10.1172/ JCI31516. (Pubitemid 47219577)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.8
, pp. 2325-2336
-
-
Claret, M.1
Smith, M.A.2
Batterham, R.L.3
Selman, C.4
Choudhury, A.I.5
Fryer, L.G.D.6
Clements, M.7
Al-Qassab, H.8
Heffron, H.9
Xu, A.W.10
Speakman, J.R.11
Barsh, G.S.12
Viollet, B.13
Vaulont, S.14
Ashford, M.L.J.15
Carling, D.16
Withers, D.J.17
-
60
-
-
0036829858
-
Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion
-
Clegg DJ, Wortman MD, Benoit SC, Mc Osker CC, Seeley RJ. Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion. Diabetes. 2002;51(11):3196-201. (Pubitemid 35246965)
-
(2002)
Diabetes
, vol.51
, Issue.11
, pp. 3196-3201
-
-
Clegg, D.J.1
Wortman, M.D.2
Benoit, S.C.3
McOsker, C.C.4
Seeley, R.J.5
-
61
-
-
0038025293
-
C75 inhibits food intake by increasing CNS glucose metabolism [2]
-
DOI 10.1038/nm0503-483
-
Wortman MD, Clegg DJ, DAlessio D, Woods SC, Seeley RJ. C75 inhibits food intake by increasing CNS glucose metabolism. Nat Med. 2003;9(5):483-5. doi:10.1038/nm0503-483. (Pubitemid 36597076)
-
(2003)
Nature Medicine
, vol.9
, Issue.5
, pp. 483-485
-
-
Wortman, M.D.1
Clegg, D.J.2
D'Alessio, D.3
Woods, S.C.4
Seeley, R.J.5
-
62
-
-
16244388931
-
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis
-
DOI 10.1038/nm1201
-
Lam TK, Pocai A, Gutierrez-Juarez R, Obici S, Bryan J, Aguilar-Bryan L, et al. Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis. Nat Med. 2005;11(3):320-7. (Pubitemid 40460561)
-
(2005)
Nature Medicine
, vol.11
, Issue.3
, pp. 320-327
-
-
Lam, T.K.T.1
Pocai, A.2
Gutierrez-Juarez, R.3
Obici, S.4
Bryan, J.5
Aguilar-Bryan, L.6
Schwartz, G.J.7
Rossetti, L.8
-
63
-
-
0034733730
-
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
-
DOI 10.1126/science.288.5475.2379
-
Loftus TM, Jaworsky DE, Frehywot GL, Townsend CA, Ronnett GV, Lane MD, et al. Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science. 2000;288(5475):2379-81. (Pubitemid 30448165)
-
(2000)
Science
, vol.288
, Issue.5475
, pp. 2379-2381
-
-
Loftus, T.M.1
Jaworsky, D.E.2
Frehywot, C.L.3
Townsend, C.A.4
Ronnett, G.V.5
Daniel Lane, M.6
Kuhajda, F.P.7
-
64
-
-
28844433549
-
A role for hypothalamic malonyl-CoA in the control of food intake
-
DOI 10.1074/jbc.C500398200
-
Hu Z, Dai Y Prentki M, Chohnan S, Lane MD. A role for hypothalamic malonyl-Co A in the control of food intake. J Biol Chem. 2005;280(48):39681-3. (Pubitemid 41779099)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.48
, pp. 39681-39683
-
-
Hu, Z.1
Dai, Y.2
Prentki, M.3
Chohnan, S.4
Lane, M.D.5
-
65
-
-
33646012618
-
Effects of oleic acid on distinct populations of neurons in the hypothalamic arcuate nucleus are dependent on extracellular glucose levels
-
Wang R, Cruciani-Guglielmacci C, Migrenne S, Magnan C, Cotero VE, Routh VH. Effects of oleic acid on distinct populations of neurons in the hypothalamic arcuate nucleus are dependent on extracellular glucose levels. J Neurophysiol. 2006;95(3):1491-8.
-
(2006)
J Neurophysiol
, vol.95
, Issue.3
, pp. 1491-8
-
-
Wang, R.1
Cruciani-Guglielmacci, C.2
Migrenne, S.3
Magnan, C.4
Cotero, V.E.5
Routh, V.H.6
-
66
-
-
69249089757
-
Characteristics and mechanisms of hypothalamic neuronal fatty acid sensing
-
Le Foll C, Irani BG, Magnan C, Dunn-Meynell AA, Levin BE. Characteristics and mechanisms of hypothalamic neuronal fatty acid sensing. Am J Physiol Regul Integr Comp Physiol. 2009;297(3):R655-64.
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.297
, Issue.3
-
-
Le Foll, C.1
Irani, B.G.2
Magnan, C.3
Dunn-Meynell, A.A.4
Levin, B.E.5
-
67
-
-
12144284373
-
Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease
-
DOI 10.1523/JNEUROSCI.4269-04.2005
-
Andrews ZB, Horvath B, Barnstable CJ, Elsworth J, Yang L, Beal MF, et al. Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease. J Neurosci. 2005;25(1):184-91. (Pubitemid 40110779)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.1
, pp. 184-191
-
-
Andrews, Z.B.1
Horvath, B.2
Barnstable, C.J.3
Elseworth, J.4
Yang, L.5
Beal, M.F.6
Roth, R.H.7
Matthews, R.T.8
Horvath, T.L.9
-
68
-
-
0036065628
-
Central administration of oleic acid inhibits glucose production and food intake
-
Obici S, Feng Z, Morgan K, Stein D, Karkanias G, Rossetti L. Central administration of oleic acid inhibits glucose production and food intake. Diabetes. 2002;51(2):271-5. (Pubitemid 34764780)
-
(2002)
Diabetes
, vol.51
, Issue.2
, pp. 271-275
-
-
Obici, S.1
Feng, Z.2
Morgan, K.3
Stein, D.4
Karkanias, G.5
Rossetti, L.6
-
69
-
-
31544465941
-
Molecular disruption of hypothalamic nutrient sensing induces obesity
-
DOI 10.1038/nn1626, PII NN1626
-
He W, Lam TK, Obici S, Rossetti L. Molecular disruption of hypothalamic nutrient sensing induces obesity Nat Neurosci. 2006;9(2):227-33. (Pubitemid 43164546)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.2
, pp. 227-233
-
-
He, W.1
Lam, T.K.T.2
Obici, S.3
Rossetti, L.4
-
70
-
-
3843114555
-
Hypothalamic responses to long-chain fatty acids are nutritionally regulated
-
DOI 10.1074/jbc.M400458200
-
Morgan K, Obici S, Rossetti L. Hypothalamic responses to long-chain fatty acids are nutritionally regulated. J Biol Chem. 2004;279(30):31139-48. doi:10.1074/jbc.M400458200. (Pubitemid 39037776)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.30
, pp. 31139-31148
-
-
Morgan, K.1
Obici, S.2
Rossetti, L.3
-
71
-
-
33645531123
-
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats
-
doi:10.1172/JCI26640
-
Pocai A, Lam TK, Obici S, Gutierrez-Juarez R, Muse ED, Arduini A, et al. Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. J Clin Invest. 2006;116(4):1081-91. doi:10.1172/JCI26640.
-
(2006)
J Clin Invest
, vol.116
, Issue.4
, pp. 1081-91
-
-
Pocai, A.1
Lam, T.K.2
Obici, S.3
Gutierrez-Juarez, R.4
Muse, E.D.5
Arduini, A.6
-
72
-
-
67449111096
-
Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation
-
Chakravarthy MV, Zhu Y Yin L, Coleman T, Pappan KL, Marshall CA, et al. Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation. J Lipid Res. 2009;50(4):630-40.
-
(2009)
J Lipid Res
, vol.50
, Issue.4
, pp. 630-40
-
-
Chakravarthy, M.V.1
Zhu Yin, Y.L.2
Coleman, T.3
Pappan, K.L.4
Marshall, C.A.5
-
73
-
-
70349200763
-
Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents
-
Benoit SC, Kemp CJ, Elias CF, Abplanalp W, Herman JP Migrenne S, et al. Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents. J Clin Invest. 2009;119(9):2577-89.
-
(2009)
J Clin Invest
, vol.119
, Issue.9
, pp. 2577-89
-
-
Benoit, S.C.1
Kemp, C.J.2
Elias, C.F.3
Abplanalp, W.4
Herman, J.P.5
Migrenne, S.6
-
74
-
-
79955694276
-
Brain PPAR-gamma promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones
-
Lu M, Sarruf DA, Talukdar S, Sharma S, Li P, Bandyopadhyay G, et al. Brain PPAR-gamma promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nat Med. 2011;17(5):618-22.
-
(2011)
Nat Med
, vol.17
, Issue.5
, pp. 618-22
-
-
Lu, M.1
Sarruf, D.A.2
Talukdar, S.3
Sharma, S.4
Li, P.5
Bandyopadhyay, G.6
-
75
-
-
79955692835
-
A role for central nervous system PPAR-gamma in the regulation ofenergy balance
-
Ryan KK, Li B, Grayson BE, Matter EK, Woods SC, Seeley RJ. A role for central nervous system PPAR-gamma in the regulation ofenergy balance. Nat Med. 2011;17(5):623-6.
-
(2011)
Nat Med
, vol.17
, Issue.5
, pp. 623-6
-
-
Ryan, K.K.1
Li, B.2
Grayson, B.E.3
Matter, E.K.4
Woods, S.C.5
Seeley, R.J.6
-
76
-
-
39049184850
-
Gastrointestinal hormones and food intake
-
American Gastroenterological Associa-tion
-
Strader AD, Woods SC. American Gastroenterological Associa-tion. Gastrointestinal hormones and food intake. Rev Gastro-enterol Mex. 2005;70(4):439-57.
-
(2005)
Rev Gastro-enterol Mex
, vol.70
, Issue.4
, pp. 439-57
-
-
Strader, A.D.1
Woods, S.C.2
-
77
-
-
0034687376
-
Ghrelin induces adiposity in rodents
-
908-13 doi:10.1038/35038090
-
Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature. 2000;407(6806):908-13. doi:10.1038/ 35038090.
-
(2000)
Nature
, vol.407
, Issue.6806
-
-
Tschop, M.1
Smiley, D.L.2
Heiman, M.L.3
-
78
-
-
0032982267
-
Role of the vagus nerve in mediating proximal nutrient-induced glucagon- like peptide-1 secretion
-
Rocca AS, Brubaker PL. Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion. Endocrinology 1999;140(4):1687-94. (Pubitemid 29149238)
-
(1999)
Endocrinology
, vol.140
, Issue.4
, pp. 1687-1694
-
-
Rocca, A.S.1
Brubaker, P.L.2
-
79
-
-
0033545166
-
Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system
-
DOI 10.1002/(SICI)1096-9861(19990111)403:2<261::AID-CNE8>3.0.CO;2-5
-
Merchenthaler I, Lane M, Shughrue P Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system. J Comp Neurol. 1999;403 (2):261-80. doi:10.1002/(SICI)1096- 9861(19990111) 403:23.0.CO;2-5. (Pubitemid 28566834)
-
(1999)
Journal of Comparative Neurology
, vol.403
, Issue.2
, pp. 261-280
-
-
Merchenthaler, I.1
Lane, M.2
Shughrue, P.3
-
80
-
-
0022509255
-
Cellular localization of proglucagon/glucagon-like peptide I messenger RNAs in rat brain
-
Han VK, Hynes MA, Jin C, Towle AC, Lauder JM, Lund PK. Cellular localization of proglucagon/glucagon-like peptide I messenger RNAs in rat brain. J Neurosci Res. 1986;16(1):97-107. doi:10.1002/jnr.490160110. (Pubitemid 16050410)
-
(1986)
Journal of Neuroscience Research
, vol.16
, Issue.1
, pp. 97-107
-
-
Han, V.K.M.1
Hynes, M.A.2
Jin, C.3
-
81
-
-
0032756657
-
Glucagon-like peptide-1 (7-36) amide: A central regulator of satiety and interoceptive stress
-
DOI 10.1054/npep.1999.0053
-
van Dijk G, Thiele TE. Glucagon-like peptide-1 (7-36) amide: a central regulator of satiety and interoceptive stress. Neuro-peptides. 1999;33(5):406-14. doi:10.1054/npep.1999.0053. (Pubitemid 29530133)
-
(1999)
Neuropeptides
, vol.33
, Issue.5
, pp. 406-414
-
-
Dijk, G.V.1
Thiele, T.E.2
-
82
-
-
0032504654
-
Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem
-
DOI 10.1016/S0006-8993(98)00584-8, PII S0006899398005848
-
Thiele TE, Seeley RJ, DAlessio D, Eng J, Bernstein IL, Woods SC, et al. Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem. Brain Res. 1998;801 (1-2):164-70. (Pubitemid 28401660)
-
(1998)
Brain Research
, vol.801
, Issue.1-2
, pp. 164-170
-
-
Thiele, T.E.1
Seeley, R.J.2
D'Alessio, D.3
Eng, J.4
Bernstein, I.L.5
Woods, S.C.6
Van Dijk, G.7
-
83
-
-
0036307872
-
Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons
-
DOI 10.1172/JCI200215595
-
Yamamoto H, Lee CE, Marcus JN, Williams TD, Overton JM, Lopez ME, et al. Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. J Clin Invest. 2002;110(1):43-52. doi:10.1172/ JCI15595. (Pubitemid 34743464)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.1
, pp. 43-52
-
-
Yamamoto, H.1
Lee, C.E.2
Marcus, J.N.3
Williams, T.D.4
Michael Overton, J.5
Lopez, M.E.6
Hollenberg, A.N.7
Baggio, L.8
Saper, C.B.9
Drucker, D.J.10
Elmquist, J.K.11
-
84
-
-
23844446798
-
Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system
-
DOI 10.1016/j.peptides.2005.02.016, PII S0196978105000690
-
Osaka T, Endo M, Yamakawa M, Inoue S. Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system. Peptides. 2005;26(9):1623-31. (Pubitemid 41169757)
-
(2005)
Peptides
, vol.26
, Issue.9
, pp. 1623-1631
-
-
Osaka, T.1
Endo, M.2
Yamakawa, M.3
Inoue, S.4
-
85
-
-
13344282056
-
A role for glucagon-like peptide-1 in the central regulation of feeding
-
DOI 10.1038/379069a0
-
Turton MD, O'Shea D, Gunn I, Beak SA, Edwards CM, Meeran K, et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature. 1996;379(6560):69-72. doi:10.1038/379069a0. (Pubitemid 26008136)
-
(1996)
Nature
, vol.379
, Issue.6560
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.3
Beak, S.A.4
Edwards, C.M.B.5
Meeran, K.6
Choi, S.J.7
Taylor, G.M.8
Heath, M.M.9
Lambert, P.D.10
Wilding, J.P.H.11
Smith, D.M.12
Ghatei, M.A.13
Herbert, J.14
Bloom, S.R.15
-
86
-
-
0033051923
-
Central administration of leptin inhibits food intake and activates the sympathetic nervous system in rhesus macaques
-
DOI 10.1210/jc.84.2.711
-
Tang-Christensen M, Havel PJ, Jacobs RR, Larsen PJ, Cameron JL. Central administration of leptin inhibits food intake and activates the sympathetic nervous system in rhesus macaques. J Clin Endocrinol Metab. 1999;84(2):711-7. (Pubitemid 29075710)
-
(1999)
Journal of Clinical Endocrinology and Metabolism
, vol.84
, Issue.2
, pp. 711-717
-
-
Tang-Christensen, M.1
Havel, P.J.2
Jacobs, R.R.3
Larsen, P.J.4
Cameron, J.L.5
-
87
-
-
0031020391
-
Glucagon-like peptide-1 and satiety
-
doi:10.1038/385214a0
-
Van Dijk G, Thiele TE, Seeley RJ, Woods SC, Bernstein IL. Glucagon-like peptide-1 and satiety Nature. 1997;385 (6613):214. doi:10.1038/385214a0.
-
(1997)
Nature
, vol.385
, Issue.6613
, pp. 214
-
-
Van Dijk, G.1
Thiele, T.E.2
Seeley, R.J.3
Woods, S.C.4
Bernstein, I.L.5
-
88
-
-
0031695395
-
Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men
-
Naslund E, Gutniak M, Skogar S, Rossner S, Hellstrom PM. Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men. Am J Clin Nutr 1998;68(3):525-30. (Pubitemid 28402372)
-
(1998)
American Journal of Clinical Nutrition
, vol.68
, Issue.3
, pp. 525-530
-
-
Naslund, E.1
Gutniak, M.2
Skogar, S.3
Rossner, S.4
Hellstrom, P.M.5
-
89
-
-
0034011021
-
The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans
-
Flint A, Raben A, Rehfeld JF, Holst JJ, Astrup A. The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans. Int J Obes Relat Metab Disord. 2000;24 (3):288-98. (Pubitemid 30137718)
-
(2000)
International Journal of Obesity
, vol.24
, Issue.3
, pp. 288-298
-
-
Flint, A.1
Raben, A.2
Rehfeld, J.F.3
Holst, J.J.4
Astrup, A.5
-
90
-
-
6344260130
-
Attenuation of lipopolysaccharide anorexia by antagonism of caudal brain stem but not forebrain GLP-1-R
-
DOI 10.1152/ajpregu.00163.2004
-
Grill HJ, Carmody JS, Amanda Sadacca L, Williams DL, Kaplan JM. Attenuation of lipopolysaccharide anorexia by antagonism of caudal brain stem but not forebrain GLP-1-R. Am J Physiol Regul Integr Comp Physiol. 2004;287(5):R1190-3. doi:10.1152/ ajpregu.00163.2004. (Pubitemid 39391064)
-
(2004)
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
, vol.287
, Issue.5
-
-
Grill, H.J.1
Carmody, J.S.2
Sadacca, L.A.3
Williams, D.L.4
Kaplan, J.M.5
-
91
-
-
0031891391
-
PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats
-
Mc Mahon LR, Wellman PJ. PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats. Am J Physiol. 1998;274(1 Pt 2):R23-9.
-
(1998)
Am J Physiol
, vol.274
, Issue.1 PART 2
-
-
Mc Mahon, L.R.1
Wellman, P.J.2
-
92
-
-
50949094723
-
Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake
-
Sandoval DA, Bagnol D, Woods SC, DAlessio DA, Seeley RJ. Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake. Diabetes. 2008;57(8):2046-54.
-
(2008)
Diabetes
, vol.57
, Issue.8
, pp. 2046-54
-
-
Sandoval, D.A.1
Bagnol, D.2
Woods, S.C.3
Dalessio, D.A.4
Seeley, R.J.5
-
93
-
-
3042847469
-
Importance of orexigenic counter-regulation for multiple targeted feeding inhibition
-
Schusdziarra V, Zimmermann JP, Schick RR. Importance of orexigenic counter-regulation for multiple targeted feeding inhibition. Obes Res. 2004;12(4):627-32. (Pubitemid 41132505)
-
(2004)
Obesity Research
, vol.12
, Issue.4
, pp. 627-632
-
-
Schusdziarra, V.1
Zimmermann, J.P.2
Schick, R.R.3
-
94
-
-
0030770640
-
Influence of fasting and neuropeptide Y on the suppressive food intake induced by intracerebroventricular injection of glucagon-like peptide-1 in the neonatal chick
-
DOI 10.1016/S0006-8993(97)00623-9, PII S0006899397006239
-
Furuse M, Matsumoto M, Mori R, Sugahara K, Kano K, Hasegawa S. Influence of fasting and neuropeptide Y on the suppressive food intake induced by intracerebroventricular injection ofglucagon-like peptide-1 in the neonatal chick. Brain Res. 1997;764(1-2):289-92. (Pubitemid 27380673)
-
(1997)
Brain Research
, vol.764
, Issue.1-2
, pp. 289-292
-
-
Furuse, M.1
Matsumoto, M.2
Mori, R.3
Sugahara, K.4
Kano, K.5
Hasegawa, S.6
-
95
-
-
0031697756
-
Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus
-
DOI 10.2337/diabetes.47.11.1687
-
Tritos NA, Vicent D, Gillette J, Ludwig DS, Flier ES, Maratos-Flier E. Functional interactions between melanin-concentrating hormone, neuropeptide Y and anorectic neuropeptides in the rat hypothalamus. Diabetes. 1998;47:1687-92. (Pubitemid 28476241)
-
(1998)
Diabetes
, vol.47
, Issue.11
, pp. 1687-1692
-
-
Tritos, N.A.1
Vicent, D.2
Gillette, J.3
Ludwig, D.S.4
Flier, E.S.5
Maratos-Flier, E.6
-
96
-
-
0034595765
-
Cocaine- and amphetamine-regulated transcript, glucagon-like peptide-1 and corticotrophin releasing factor inhibit feeding via agouti-related protein independent pathways in the rat
-
DOI 10.1016/S0006-8993(00)02257-5, PII S0006899300022575
-
Edwards CM, Abbott CR, Sunter D, Kim M, Dakin CL, Murphy KG, et al. Cocaine- and amphetamine-regulated transcript, glucagon-like peptide-1 and corticotrophin releasing factor inhibit feeding via agouti-related protein independent pathways in the rat. Brain Res. 2000;866(1-2):128-34. (Pubitemid 30313015)
-
(2000)
Brain Research
, vol.866
, Issue.1-2
, pp. 128-134
-
-
Edwards, C.M.B.1
Abbott, C.R.2
Sunter, D.3
Kim, M.-S.4
Dakin, C.L.5
Murphy, K.G.6
Abusnana, S.7
Taheri, S.8
Rossi, M.9
Bloom, S.R.10
-
97
-
-
0031964636
-
Intraventricular GLP-1 reduces short- but not long-term food intake or body weight in lean and obese rats
-
DOI 10.1016/S0006-8993(97)01057-3, PII S0006899397010573
-
Donahey JC, van Dijk G, Woods SC, Seeley RJ. Intraventricular GLP-1 reduces short- but not long-term food intake or body weight in lean and obese rats. Brain Res. 1998;779(1-2):75-83. (Pubitemid 28039941)
-
(1998)
Brain Research
, vol.779
, Issue.1-2
, pp. 75-83
-
-
Donahey, J.C.K.1
Van Dijk, G.2
Woods, S.C.3
Seeley, R.J.4
-
98
-
-
27744607262
-
Utilizing the GLP-1 signaling system to treat diabetes: Sorting through the pharmacologic approaches
-
D'Alessio DA, Vahl TP Utilizing the GLP-1 signaling system to treat diabetes: sorting through the pharmacologic approaches. Curr Diab Rep. 2005;5(5):346-52. (Pubitemid 41600776)
-
(2005)
Current Diabetes Reports
, vol.5
, Issue.5
, pp. 346-352
-
-
D'Alessio, D.A.1
Vahl, T.P.2
-
99
-
-
34547586659
-
Reduced incretin effect in type 2 diabetes: Cause or consequence of the diabetic state?
-
DOI 10.2337/db07-0100
-
Knop FK, Vilsboll T, Hojberg PV, Larsen S, Madsbad S, Volund A, et al. Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state? Diabetes. 2007;56(8):1951-9. (Pubitemid 47195814)
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 1951-1959
-
-
Knop, F.K.1
Vilsboll, T.2
Hojberg, P.V.3
Larsen, S.4
Madsbad, S.5
Volund, A.6
Holst, J.J.7
Krarup, T.8
-
100
-
-
0032940582
-
Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat
-
DOI 10.1210/en.140.1.244
-
Meeran K, O'Shea D, Edwards CM, Turton MD, Heath MM, Gunn I, et al. Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat Endocrinology 1999;140(1):244-50. (Pubitemid 29011165)
-
(1999)
Endocrinology
, vol.140
, Issue.1
, pp. 244-250
-
-
Meeran, K.1
O'Shea, D.2
Edwards, C.M.B.3
Turton, M.D.4
Heath, M.M.5
Gunn, I.6
Abusnana, S.7
Rossi, M.8
Small, C.J.9
Goldstone, A.P.10
Taylor, G.M.11
Sunter, D.12
Steere, J.13
Choi, S.J.14
Ghatei, M.A.15
Bloom, S.R.16
-
101
-
-
0029958404
-
Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene
-
DOI 10.1038/nm1196-1254
-
Scrocchi LA, Brown TJ, Ma Clusky N, Brubaker PL, Auerbach AB, Joyner AL, et al. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat Med. 1996;2(11):1254-8. (Pubitemid 26375413)
-
(1996)
Nature Medicine
, vol.2
, Issue.11
, pp. 1254-1258
-
-
Scrocchi, L.A.1
Brown, T.J.2
MacLusky, N.3
Brubaker, P.L.4
Auerbach, A.B.5
Joyner, A.L.6
Drucker, D.J.7
-
102
-
-
0031731090
-
Effects of aging and a high fat diet on body weight and glucose tolerance in glucagon-like peptide-1 receptor(-/-) mice
-
DOI 10.1210/en.139.7.3127
-
Scrocchi LA, Drucker DJ. Effects ofaging and a high fat diet on body weight and glucose tolerance in glucagon-like peptide-1 receptor-/-mice. Endocrinology 1998;139(7):3127-32. (Pubitemid 28512341)
-
(1998)
Endocrinology
, vol.139
, Issue.7
, pp. 3127-3132
-
-
Scrocchi, L.A.1
Drucker, D.J.2
-
103
-
-
33845997750
-
Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure
-
DOI 10.1172/JCI25483
-
Hansotia T, Maida A, Flock G, Yamada Y, Tsukiyama K, Seino Y et al. Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure. J Clin Invest. 2007;117(1):143-52. doi:10.1172/JCI25483. (Pubitemid 46048461)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 143-152
-
-
Hansotia, T.1
Maida, A.2
Flock, G.3
Yamada, Y.4
Tsukiyama, K.5
Seino, Y.6
Drucker, D.J.7
-
104
-
-
55849125147
-
Role of central nervous system glucagon-like Peptide-1 receptors in enteric glucose sensing
-
Knauf C, Cani PD, Kim DH, Iglesias MA, Chabo C, Waget A, et al. Role of central nervous system glucagon-like Peptide-1 receptors in enteric glucose sensing. Diabetes. 2008;57 (10):2603-12.
-
(2008)
Diabetes
, vol.57
, Issue.10
, pp. 2603-12
-
-
Knauf Cani, C.P.D.1
Kim, D.H.2
Iglesias, M.A.3
Chabo, C.4
Waget, A.5
-
105
-
-
0035030765
-
Sibutramine reduces feeding, body fat and improves insulin resistance in dietary-obese male Wistar rats independently of hypothalamic neuropeptide Y
-
Brown M, Bing C, King P, Pickavance L, Heal D, Wilding J. Sibutramine reduces feeding, body fat and improves insulin resistance in dietary-obese male Wistar rats independently of hypothalamic neuropeptide Y Br J Pharmacol. 2001;132 (8):1898-904. doi:10.1038/sj.bjp.0704030. (Pubitemid 32397982)
-
(2001)
British Journal of Pharmacology
, vol.132
, Issue.8
, pp. 1898-1904
-
-
Brown, M.1
Bing, C.2
King, P.3
Pickavance, L.4
Heal, D.5
Wilding, J.6
-
106
-
-
0033048184
-
Intracerebroventricular administration of bromocriptine ameliorates the insulin-resistant/glucose-intolerant state in hamsters
-
Luo S, Liang Y, Cincotta AH. Intracerebroventricular adminis-tration ofbromocriptine ameliorates the insulin-resistant/glucose-intolerant state in hamsters. Neuroendocrinology 1999;69 (3):160-6. (Pubitemid 29134491)
-
(1999)
Neuroendocrinology
, vol.69
, Issue.3
, pp. 160-166
-
-
Luo, S.1
Liang, Y.2
Cincotta, A.H.3
-
107
-
-
0030754560
-
Bromocriptine/SKF38393 treatment ameliorates obesity and associated metabolic dysfunctions in obese (ob/ob) mice
-
DOI 10.1016/S0024-3205(97)00599-7, PII S0024320597005997
-
Cincotta AH, Tozzo E, Scislowski PW Bromocriptine/SKF38393 treatment ameliorates obesity and associated metabolic dysfunc-tions in obese (ob/ob) mice. Life Sci. 1997;61(10):951-6. (Pubitemid 27348663)
-
(1997)
Life Sciences
, vol.61
, Issue.10
, pp. 951-956
-
-
Cincotta, A.H.1
Tozzo, E.2
Scislowski, P.W.D.3
-
108
-
-
0020627013
-
Norepinephrine and dopamine levels in hypothalamic nuclei of the genetically obese mouse (ob/ob)
-
DOI 10.1016/0006-8993(83)90865-X
-
Oltmans GA. Norepinephrine and dopamine levels in hypotha-lamic nuclei of the genetically obese mouse (ob/ob). Brain Res. 1983;273(2):369-73. (Pubitemid 13039723)
-
(1983)
Brain Research
, vol.273
, Issue.2
, pp. 369-373
-
-
Oltmans, G.A.1
-
109
-
-
0027537471
-
Ventrolateral striatal dopamine depletions impair feeding and food handling in rats
-
Salamone JD, Mahan K, Rogers S. Ventrolateral striatal dopamine depletions impair feeding and food handling in rats. Pharmacol Biochem Behav. 1993;44(3):605-10.
-
(1993)
Pharmacol Biochem Behav
, vol.44
, Issue.3
, pp. 605-10
-
-
Salamone, J.D.1
Mahan, K.2
Rogers, S.3
-
110
-
-
0032694280
-
Feeding behavior in dopamine-deficient mice
-
DOI 10.1073/pnas.96.21.12138
-
Szczypka MS, Rainey MA, Kim DS, Alaynick WA, Marck BT, Matsumoto AM, et al. Feeding behavior in dopamine-deficient mice. Proc Natl Acad Sci USA. 1999;96(21):12138-43. (Pubitemid 29502871)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.21
, pp. 12138-12143
-
-
Szczypka, M.S.1
Rainey, M.A.2
Kim, D.S.3
Alaynick, W.A.4
Marck, B.T.5
Matsumoto, A.M.6
Palmiter, R.D.7
-
111
-
-
0031806149
-
Food deprivation decreases mRMA and activity of the rat dopamine transporter
-
DOI 10.1159/000054345
-
Patterson TA, Brot MD, Zavosh A, Schenk JO, Szot P, Figlewicz DP Food deprivation decreases m RNA and activity of the rat dopaminetransporter. Neuroendocrinology 1998;68(1):11-20. (Pubitemid 28310604)
-
(1998)
Neuroendocrinology
, vol.68
, Issue.1
, pp. 11-20
-
-
Patterson, T.A.1
Brot, M.D.2
Zavosh, A.3
Schenk, J.O.4
Szot, P.5
Figlewicz, D.P.6
Figlewicz Lattermann, D.7
-
112
-
-
25144456112
-
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
-
DOI 10.1056/NEJMoa051688
-
Lieberman JA, Stroup TS, Mc Evoy JP, Swartz MS, Rosenheck RA, Perkins DO, et al. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med. 2005;353 (12):1209-23. (Pubitemid 41345943)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.12
, pp. 1209-1223
-
-
Lieberman, J.A.1
Scott Stroup, T.2
McEvoy, J.P.3
Swartz, M.S.4
Rosenheck, R.A.5
Perkins, D.O.6
Keefe, R.S.E.7
Davis, S.M.8
Davis, C.E.9
Lebowitz, B.D.10
Severe, J.11
Hsiao, J.K.12
-
113
-
-
14644415476
-
Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: A placebo-controlled study of olanzapine and risperidone in dogs
-
DOI 10.2337/diabetes.54.3.862
-
Ader M, Kim SP, Catalano KJ, Ionut V, Hucking K, Richey JM, et al. Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs. Diabetes. 2005;54 (3):862-71. (Pubitemid 40322092)
-
(2005)
Diabetes
, vol.54
, Issue.3
, pp. 862-871
-
-
Ader, M.1
Kim, S.P.2
Catalano, K.J.3
Ionut, V.4
Hucking, K.5
Richey, J.M.6
Kabir, M.7
Bergman, R.N.8
-
114
-
-
33846264544
-
Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: Implications for adverse metabolic effects
-
DOI 10.1038/sj.npp.1301209, PII 1301209
-
Houseknecht KL, Robertson AS, Zavadoski W, Gibbs EM, Johnson DE, Rollema H. Acute effects ofatypical antipsychotics on whole-body insulin resistance in rats: implications for adverse metabolic effects. Neuropsychopharmacology. 2007;32(2):289-97. (Pubitemid 46106936)
-
(2007)
Neuropsychopharmacology
, vol.32
, Issue.2
, pp. 289-297
-
-
Houseknecht, K.L.1
Robertson, A.S.2
Zavadoski, W.3
Gibbs, E.M.4
Johnson, D.E.5
Rollema, H.6
-
115
-
-
58149109332
-
Insulin resistance and decreased glucose-stimulated insulin secre-tion after acute olanzapine administration
-
doi:10.1097/JCP0b013e318184b4c5
-
Chintoh AF, Mann SW, Lam L, Lam C, Cohn TA, Fletcher PJ, et al. Insulin resistance and decreased glucose-stimulated insulin secre-tion after acute olanzapine administration. J Clin Psychopharmacol. 2008;28(5):494-9. doi:10.1097/JCP0b013e318184b4c5.
-
(2008)
J Clin Psychopharmacol
, vol.28
, Issue.5
, pp. 494-9
-
-
Chintoh, A.F.1
Mann, S.W.2
Lam, L.3
Lam, C.4
Cohn, T.A.5
Fletcher, P.J.6
-
116
-
-
77956426326
-
Insulin resistance and metabolic profile in antipsychotic naive schizo-phrenia patients
-
Dasgupta A, Singh OP, Rout JK, Saha T, Mandal S. Insulin resistance and metabolic profile in antipsychotic naive schizo-phrenia patients. Prog Neuropsychopharmacol Biol Psychiatry. 2010;34(7):1202-7.
-
(2010)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.34
, Issue.7
, pp. 1202-7
-
-
Dasgupta, A.1
Singh, O.P.2
Rout, J.K.3
Saha, T.4
Mandal, S.5
-
117
-
-
77953939932
-
Impact of serotonin receptor 2A gene haplotypes on C-peptide levels in clozapine- and olanzapine-treated patients
-
doi:10.1002/hup.1114
-
Melkersson KI, Gunes A, Dahl ML. Impact of serotonin receptor 2A gene haplotypes on C-peptide levels in clozapine- and olanzapine-treated patients. Hum Psychopharmacol. 2010;25 (4):347-52. doi:10.1002/hup.1114.
-
(2010)
Hum Psychopharmacol
, vol.25
, Issue.4
, pp. 347-52
-
-
Melkersson, K.I.1
Gunes, A.2
Dahl, M.L.3
-
118
-
-
62649090828
-
HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia: A replication study
-
doi:10.1097/ JCP0b013e3181934462
-
Mulder H, Cohen D, Scheffer H, Gispen-de Wied C, Arends J, Wilmink FW, et al. HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia: a replication study. J Clin Psychopharmacol. 2009;29(1):16-20. doi:10.1097/ JCP0b013e3181934462.
-
(2009)
J Clin Psychopharmacol
, vol.29
, Issue.1
, pp. 16-20
-
-
Mulder, H.1
Cohen, D.2
Scheffer, H.3
Gispen-De Wied, C.4
Arends, J.5
Wilmink, F.W.6
-
119
-
-
15944385300
-
1B receptors in the hypophagic effect of 5-HT on the structure of feeding behavior
-
Mancilla-Diaz JM, Escartin-Perez RE, Lopez-Alonso VE, Floran-Garduno B, Romano-Camacho JB. Role of 5-HT1A and 5-HT1B receptors in the hypophagic effect of 5-HT on the structure of feeding behavior Med Sci Monit 2005;11(3):BR74-9. (Pubitemid 40445975)
-
(2005)
Medical Science Monitor
, vol.11
, Issue.3
-
-
Mancilla-Diaz, J.M.1
Escartin-Perez, R.E.2
Lopez-Alonso, V.E.3
Floran-Garduno, B.4
Romano-Camacho, J.B.5
-
120
-
-
0032213142
-
Hypothalamic serotonin in control of eating behavior, meal size, and body weight
-
DOI 10.1016/S0006-3223(98)00186-3, PII S0006322398001863
-
Leibowitz SF, Alexander JT. Hypothalamic serotonin in control of eating behavior, meal size, and body weight. Biol Psychiatry. 1998;44(9):851-64. (Pubitemid 28520223)
-
(1998)
Biological Psychiatry
, vol.44
, Issue.9
, pp. 851-864
-
-
Leibowitz, S.F.1
Alexander, J.T.2
-
121
-
-
33646896967
-
Effects of chronic fenfluramine administration on hypothalamic neuropeptide mRNA expression
-
DOI 10.1016/j.brainres.2006.02.129, PII S0006899306007189
-
Choi S, Blake V, Cole S, Fernstrom JD. Effects of chronic fenfluramine administration on hypothalamic neuropeptide m RNA expression. Brain Res. 2006;1087(1):83-6. (Pubitemid 43783148)
-
(2006)
Brain Research
, vol.1087
, Issue.1
, pp. 83-86
-
-
Choi, S.1
Blake, V.2
Cole, S.3
Fernstrom, J.D.4
-
122
-
-
0031721271
-
Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT(2C) receptor gene
-
DOI 10.1038/2647
-
Nonogaki K, Strack AM, Dallman MF, Tecott LH. Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene. Nat Med. 1998;4 (10):1152-6. doi:10.1038/2647. (Pubitemid 28468828)
-
(1998)
Nature Medicine
, vol.4
, Issue.10
, pp. 1152-1156
-
-
Nonogaki, K.1
Strack, A.M.2
Dallman, M.F.3
Tecott, L.H.4
-
123
-
-
56349145180
-
5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis
-
Xu Y, Jones JE, Kohno D, Williams KW, Lee CE, Choi MJ, et al. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. Neuron. 2008;60(4):582-9.
-
(2008)
Neuron
, vol.60
, Issue.4
, pp. 582-9
-
-
Xu, Y.1
Jones, J.E.2
Kohno, D.3
Williams, K.W.4
Lee, C.E.5
Choi, M.J.6
-
124
-
-
0029317572
-
Amino acids and glucose differentially increased extracellular 5-hydroxyindoleacetic acid in the rat brain
-
Yamauchi A, Shizuka F, Yamamoto T, Nikawa T, Kido Y Rokutan K, et al. Amino acids and glucose differentially increased extracellular 5-hydroxyindoleacetic acid in the rat brain. J Nutr Sci Vitaminol (Tokyo). 1995;41(3):325-40.
-
(1995)
J Nutr Sci Vitaminol (Tokyo)
, vol.41
, Issue.3
, pp. 325-40
-
-
Yamauchi, A.1
Shizuka, F.2
Yamamoto, T.3
Nikawa, T.4
Kido Rokutan, Y.K.5
-
125
-
-
0041357080
-
Inflammation and its association with glucose disorders and cardiovascular disease
-
DOI 10.2165/00024677-200302020-00002
-
Barzilay J, Freedland E. Inflammation and its association with glucose disorders and cardiovascular disease. Treat Endocrinol. 2003;2(2):85-94. (Pubitemid 37055611)
-
(2003)
Treatments in Endocrinology
, vol.2
, Issue.2
, pp. 85-94
-
-
Barzilay, J.1
Freedland, E.2
-
126
-
-
33746722145
-
Hypothalamic integration of immune function and metabolism
-
Guijarro A, Laviano A, Meguid MM. Hypothalamic integration of immune function and metabolism. Prog Brain Res. 2006;153:367-405.
-
(2006)
Prog Brain Res
, vol.153
, pp. 367-405
-
-
Guijarro, A.1
Laviano, A.2
Meguid, M.M.3
-
127
-
-
0141743347
-
On the site and mechanism of action of the anti-obesity effects of interleukin-6
-
DOI 10.1016/S1096-6374(03)00051-0
-
Jansson JO, Wallenius K, Wernstedt I, Ohlsson C, Dickson SL, Wallenius V. On the site and mechanism of action of the anti-obesity effects ofinterleukin-6. Growth Horm IGF Res. 2003;13 (Suppl A):S28-32. (Pubitemid 37161653)
-
(2003)
Growth Hormone and IGF Research
, vol.13
, Issue.SUPPL. A
-
-
Jansson, J.-O.1
Wallenius, K.2
Wernstedt, I.3
Ohlsson, C.4
Dickson, S.L.5
Wallenius, V.6
-
128
-
-
0006238591
-
The insulin equivalence of salicylate
-
Reid J, Lightbody TD. The insulin equivalence of salicylate. Br Med J. 1959;1(5126):897-900.
-
(1959)
Br Med J
, vol.1
, Issue.5126
, pp. 897-900
-
-
Reid, J.1
Lightbody, T.D.2
-
129
-
-
0035979775
-
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkβ
-
DOI 10.1126/science.1061620
-
Yuan M, Konstantopoulos N, Lee J, Hansen L, Li ZW, Karin M, et al. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science. 2001;293(5535):1673-7. doi: 10.1126/science.1061620. (Pubitemid 32807849)
-
(2001)
Science
, vol.293
, Issue.5535
, pp. 1673-1677
-
-
Yuan, M.1
Konstantopoulos, N.2
Lee, J.3
Hansen, L.4
Li, Z.-W.5
Karin, M.6
Shoelson, S.E.7
-
130
-
-
0032487857
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β
-
DOI 10.1038/23948
-
Yin MJ, Yamamoto Y Gaynor RB. The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature. 1998;396(6706):77-80. doi:10.1038/23948. (Pubitemid 28520452)
-
(1998)
Nature
, vol.396
, Issue.6706
, pp. 77-80
-
-
Yin, M.-J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
131
-
-
0036099857
-
Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes
-
DOI 10.1172/JCI200214955
-
Hundal RS, Petersen KF, Mayerson AB, Randhawa PS, Inzucchi S, Shoelson SE, et al. Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. J Clin Invest 2002;109(10):1321-6. doi:10.1172/JCI14955. (Pubitemid 34546896)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.10
, pp. 1321-1326
-
-
Hundal, R.S.1
Petersen, K.F.2
Mayerson, A.B.3
Randhawa, P.S.4
Inzucchi, S.5
Shoelson, S.E.6
Shulman, G.I.7
-
132
-
-
0034105064
-
How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli
-
Rivest S, Lacroix S, Vallieres L, Nadeau S, Zhang J, Laflamme N. How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli. Proc Soc Exp Biol Med. 2000;223(1):22-38. (Pubitemid 30182654)
-
(2000)
Proceedings of the Society for Experimental Biology and Medicine
, vol.223
, Issue.1
, pp. 22-38
-
-
Rivest, S.1
Lacroix, S.2
Vallieres, L.3
Nadeau, S.4
Zhang, J.5
Laflamme, N.6
-
133
-
-
52949096557
-
Hypothalamic IKKbeta/NF-kappa B and ER stress link over-nutrition to energy imbalance and obesity
-
Zhang X, Zhang G, Zhang H, Karin M, Bai H, Cai D. Hypothalamic IKKbeta/NF-kappa B and ER stress link over-nutrition to energy imbalance and obesity. Cell. 2008;135 (1):61-73.
-
(2008)
Cell
, vol.135
, Issue.1
, pp. 61-73
-
-
Zhang, X.1
Zhang, G.2
Zhang, H.3
Karin, M.4
Bai, H.5
Cai, D.6
-
134
-
-
77950532905
-
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism
-
Belgardt BF, Mauer J, Wunderlich FT, Ernst MB, Pal M, Spohn G, et al. Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism. Proc Natl Acad Sci USA. 2010;107(13):6028-33.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.13
, pp. 6028-33
-
-
Belgardt, B.F.1
Mauer, J.2
Wunderlich, F.T.3
Ernst, M.B.4
Pal, M.5
Spohn, G.6
-
135
-
-
0034099771
-
Chronic infusion of norepinephrine into the VMH of normal rats induces the obese glucose-intolerant state
-
Cincotta AH, Luo S, Zhang Y, Liang Y, Bina KG, Jetton TL, et al. Chronic infusion of norepinephrine into the VMH of normal rats induces the obese glucose-intolerant state. Am J Physiol Regul Integr Comp Physiol. 2000;278(2):R435-44. (Pubitemid 30129634)
-
(2000)
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
, vol.278
, Issue.2
-
-
Cincotta, A.H.1
Luo, S.2
Zhang, Y.3
Liang, Y.4
Bina, K.G.5
Jetton, T.L.6
Scislowski, P.W.D.7
-
136
-
-
66149118129
-
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
-
Posey KA, Clegg DJ, Printz RL, Byun J, Morton GJ, Vivekanandan-Giri A, et al. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. Am J Physiol Endocrinol Metab. 2009;296(5): E1003-12.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, Issue.5
-
-
Posey, K.A.1
Clegg, D.J.2
Printz, R.L.3
Byun, J.4
Morton, G.J.5
Vivekanandan-Giri, A.6
-
137
-
-
74949093168
-
Functional role of c-Jun-N-terminal kinase in feeding regulation
-
Unger EK, Piper ML, Olofsson LE, Xu AW Functional role of c-Jun-N-terminal kinase in feeding regulation. Endocrinology. 2010;151(2):671-82.
-
(2010)
Endocrinology
, vol.151
, Issue.2
, pp. 671-82
-
-
Unger, E.K.1
Piper, M.L.2
Olofsson, L.E.3
Xu, A.W.4
-
138
-
-
78649622411
-
Suppressor of cytokine signaling 3 knockdown in the mediobasal hypothalamus: Counterintuitive effects on energy balance
-
De Backer MW Brans MA, van Rozen AJ, van der Zwaal EM, Luijendijk MC, Garner KG, et al. Suppressor of cytokine signaling 3 knockdown in the mediobasal hypothalamus: counterintuitive effects on energy balance. J Mol Endocrinol. 2010;45(5):341-53.
-
(2010)
J Mol Endocrinol
, vol.45
, Issue.5
, pp. 341-53
-
-
De Backer, M.W.1
Brans, M.A.2
Van Rozen, A.J.3
Van Der Zwaal, E.M.4
Luijendijk, M.C.5
Garner, K.G.6
-
139
-
-
77951194676
-
Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis
-
Reed AS, Unger EK, Olofsson LE, Piper ML, Myers Jr MG, Xu AW Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis. Diabetes. 2010;59(4):894-906.
-
(2010)
Diabetes
, vol.59
, Issue.4
, pp. 894-906
-
-
Reed, A.S.1
Unger, E.K.2
Olofsson, L.E.3
Piper, M.L.4
Myers Jr., M.G.5
Xu, A.W.6
-
140
-
-
70349484212
-
My D88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity
-
Kleinridders A, Schenten D, Konner AC, Belgardt BF, Mauer J, Okamura T, et al. My D88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Cell Metab. 2009;10(4):249-59.
-
(2009)
Cell Metab
, vol.10
, Issue.4
, pp. 249-59
-
-
Kleinridders, A.1
Schenten, D.2
Konner, A.C.3
Belgardt, B.F.4
Mauer, J.5
Okamura, T.6
-
141
-
-
58849149821
-
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signal-ing in hypothalamus: Implications for the pathogenesis of obesity
-
Milanski M, Degasperi G, Coope A, Morari J, Denis R, Cintra DE, et al. Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signal-ing in hypothalamus: implications for the pathogenesis of obesity J Neurosci. 2009;29(2):359-70.
-
(2009)
J Neurosci
, vol.29
, Issue.2
, pp. 359-70
-
-
Milanski, M.1
Degasperi, G.2
Coope, A.3
Morari, J.4
Denis, R.5
Cintra, D.E.6
-
142
-
-
57849115277
-
Endoplasmic reticulum stress plays a central role in development of leptin resistance
-
Ozcan L, Ergin AS, Lu A, Chung J, Sarkar S, Nie D, et al. Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab. 2009;9(1):35-51.
-
(2009)
Cell Metab
, vol.9
, Issue.1
, pp. 35-51
-
-
Ozcan, L.1
Ergin, A.S.2
Lu, A.3
Chung, J.4
Sarkar, S.5
Nie, D.6
-
143
-
-
23244458439
-
Medicine: Regulation of blood glucose by hypothalamic pyruvate metabolism
-
DOI 10.1126/science.1112085
-
Lam TK, Gutierrez-Juarez R, Pocai A, Rossetti L. Regulation of blood glucose by hypothalamic pyruvate metabolism. Science. 2005;309(5736):943-7. (Pubitemid 41099933)
-
(2005)
Science
, vol.309
, Issue.5736
, pp. 943-947
-
-
Lam, T.K.T.1
Gutierrez-Juarez, R.2
Pocai, A.3
Rossetti, L.4
-
144
-
-
17844379717
-
ATP channels control hepatic glucose production
-
DOI 10.1038/nature03439
-
Pocai A, Lam TK, Gutierrez-Juarez R, Obici S, Schwartz GJ, Bryan J, et al. Hypothalamic K(ATP) channels control hepatic glucose production. Nature. 2005;434(7036):1026-31. (Pubitemid 40586051)
-
(2005)
Nature
, vol.434
, Issue.7036
, pp. 1026-1031
-
-
Pocal, A.1
Lam, T.K.T.2
Gutierrez-Juarez, R.3
Obici, S.4
Schwartz, G.J.5
Bryan, J.6
Aguilar-Bryan, L.7
Rossetti, L.8
-
145
-
-
0038037734
-
Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production
-
DOI 10.1038/nm873
-
Obici S, Feng Z, Arduini A, Conti R, Rossetti L. Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production. Nat Med. 2003;9(6):756-61. doi:10.1038/nm873. (Pubitemid 36749226)
-
(2003)
Nature Medicine
, vol.9
, Issue.6
, pp. 756-761
-
-
Obici, S.1
Feng, Z.2
Arduini, A.3
Conti, R.4
Rossetti, L.5
-
146
-
-
42549118500
-
Upper intestinal lipids trigger a gut-brain-liver axis to regulate glucose production
-
DOI 10.1038/nature06852, PII NATURE06852
-
Wang PY, Caspi L, Lam CK, Chari M, Li X, Light PE, et al. Upper intestinal lipids trigger a gut-brain-liver axis to regulate glucose production. Nature. 2008;452(7190):1012-6. (Pubitemid 351589616)
-
(2008)
Nature
, vol.452
, Issue.7190
, pp. 1012-1016
-
-
Wang, P.Y.T.1
Caspi, L.2
Lam, C.K.L.3
Chari, M.4
Li, X.5
Light, P.E.6
Gutierrez-Juarez, R.7
Ang, M.8
Schwartz, G.J.9
Lam, T.K.T.10
-
147
-
-
33645579324
-
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production
-
Inoue H, Ogawa W, Asakawa A, Okamoto Y, Nishizawa A, Matsumoto M, et al. Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. Cell Metab. 2006;3 (4):267-75.
-
(2006)
Cell Metab
, vol.3
, Issue.4
, pp. 267-75
-
-
Inoue, H.1
Ogawa, W.2
Asakawa, A.3
Okamoto, Y.4
Nishizawa, A.5
Matsumoto, M.6
-
148
-
-
34249651956
-
Insulin action in Ag RP-expressing neurons is required for suppression of hepatic glucose production
-
DOI 10.1016/j.cmet.2007.05.004, PII S1550413107001313
-
Konner AC, Janoschek R, Plum L, Jordan SD, Rother E, Ma X, et al. Insulin action in Ag RP-expressing neurons is required for suppression of hepatic glucose production. Cell Metab. 2007;5 (6):438-49. (Pubitemid 46825497)
-
(2007)
Cell Metabolism
, vol.5
, Issue.6
, pp. 438-449
-
-
Konner, A.C.1
Janoschek, R.2
Plum, L.3
Jordan, S.D.4
Rother, E.5
Ma, X.6
Xu, C.7
Enriori, P.8
Hampel, B.9
Barsh, G.S.10
Kahn, C.R.11
Cowley, M.A.12
Ashcroft, F.M.13
Bruning, J.C.14
-
149
-
-
48749105887
-
Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats
-
doi:10.1172/JCI34277
-
Ono H, Pocai A, Wang Y, Sakoda H, Asano T, Backer JM, et al. Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats. J Clin Invest. 2008;118 (8):2959-68. doi:10.1172/JCI34277.
-
(2008)
J Clin Invest
, vol.118
, Issue.8
, pp. 2959-68
-
-
Ono, H.1
Pocai, A.2
Wang, Y.3
Sakoda, H.4
Asano, T.5
Backer, J.M.6
-
150
-
-
0008466784
-
Intracerebroventricular administration of leptin markedly enhances insulin sensitivity and systemic glucose utilization in conscious rats
-
DOI 10.1016/S0026-0495(98)90336-5
-
Shi ZQ, Nelson A, Whitcomb L, Wang J, Cohen AM. Intra-cerebroventricular administration of leptin markedly enhances insulin sensitivity and systemic glucose utilization in conscious rats. Metabolism. 1998;47(10):1274-80. (Pubitemid 28469257)
-
(1998)
Metabolism: Clinical and Experimental
, vol.47
, Issue.10
, pp. 1274-1280
-
-
Shi, Z.Q.1
Nelson, A.2
Whitcomb, L.3
Wang, J.4
Cohen, A.M.5
-
151
-
-
0032553418
-
Intracerebroventricular leptin regulates hepatic but not peripheral glucose fluxes
-
DOI 10.1074/jbc.273.47.31160
-
Liu L, Karkanias GB, Morales JC, Hawkins M, Barzilai N, Wang J, et al. Intracerebroventricular leptin regulates hepatic but not peripheral glucose fluxes. J Biol Chem. 1998;273 (47):31160-7. (Pubitemid 28533128)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.47
, pp. 31160-31167
-
-
Liu, L.1
Karkanias, G.B.2
Morales, J.C.3
Hawkins, M.4
Barzilai, N.5
Wang, J.6
Rossetti, L.7
-
153
-
-
38549176324
-
Long-term effects of central leptin and resistin on body weight, insulin resistance, and β-cell function and mass by the modulation of hypothalamic leptin and insulin signaling
-
DOI 10.1210/en.2007-0754
-
Park S, Hong SM, Sung SR, Jung HK. Long-term effects of central leptin and resistin on body weight, insulin resistance, and beta-cell function and mass by the modulation of hypothalamic leptin and insulin signaling. Endocrinology. 2008;149(2):445-54. (Pubitemid 351159338)
-
(2008)
Endocrinology
, vol.149
, Issue.2
, pp. 445-454
-
-
Park, S.1
Sang, M.H.2
So, R.S.3
Hye, K.J.4
-
154
-
-
33644686605
-
Central leptin acutely reverses diet-induced hepatic insulin resistance
-
DOI 10.2337/diabetes.54.11.3182
-
Pocai A, Morgan K, Buettner C, Gutierrez-Juarez R, Obici S, Rossetti L. Central leptin acutely reverses diet-induced hepatic insulinresistance. Diabetes. 2005;54(11):3182-9. (Pubitemid 43334373)
-
(2005)
Diabetes
, vol.54
, Issue.11
, pp. 3182-3189
-
-
Pocai, A.1
Morgan, K.2
Buettner, C.3
Gutierrez-Juarez, R.4
Obici, S.5
Rossetti, L.6
-
155
-
-
45349098372
-
Molecular and neural mediators of leptin action
-
DOI 10.1016/j.physbeh.2008.04.005, PII S0031938408001029
-
Robertson SA, Leinninger GM, Myers Jr MG. Molecular and neural mediators of leptin action. Physiol Behav. 2008;94 (5):637-42. (Pubitemid 351847627)
-
(2008)
Physiology and Behavior
, vol.94
, Issue.5
, pp. 637-642
-
-
Robertson, S.A.1
Leinninger, G.M.2
Myers Jr., M.G.3
-
156
-
-
35548942643
-
Serotonin 2C Receptor Agonists Improve Type 2 Diabetes via Melanocortin-4 Receptor Signaling Pathways
-
DOI 10.1016/j.cmet.2007.10.008, PII S1550413107003014
-
Zhou L, Sutton GM, Rochford JJ, Semple RK, Lam DD, Oksanen LJ, et al. Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways. Cell Metab. 2007;6(5):398-405. (Pubitemid 350012006)
-
(2007)
Cell Metabolism
, vol.6
, Issue.5
, pp. 398-405
-
-
Zhou, L.1
Sutton, G.M.2
Rochford, J.J.3
Semple, R.K.4
Lam, D.D.5
Oksanen, LauraJ.6
Thornton-Jones, Z.D.7
Clifton, P.G.8
Yueh, C.-Y.9
Evans, M.L.10
McCrimmon, RoryJ.11
Elmquist, J.K.12
Butler, A.A.13
Heisler, L.K.14
-
157
-
-
77957552934
-
Central nervous system delivery of the antipsychotic olanzapine induces hepatic insulin resistance
-
Martins PJ, Haas M, Obici S. Central nervous system delivery of the antipsychotic olanzapine induces hepatic insulin resistance. Diabetes. 2010;59(10):2418-25.
-
(2010)
Diabetes
, vol.59
, Issue.10
, pp. 2418-25
-
-
Martins, P.J.1
Haas, M.2
Obici, S.3
-
158
-
-
0032424694
-
Transcription factor STAT3 in leptin target neurons of the rat hypothalamus
-
DOI 10.1159/000054392
-
Hakansson ML, Meister B. Transcription factor STAT3 in leptin target neurons of the rat hypothalamus. Neuroendocrinology 1998;68(6):420-7. (Pubitemid 29000851)
-
(1998)
Neuroendocrinology
, vol.68
, Issue.6
, pp. 420-427
-
-
Hakansson, M.-L.1
Meister, B.2
-
159
-
-
0026787733
-
Beta-endorphin innervation of dopamine neurons in the rat hypothalamus: A light and electron microscopic double immunostaining study
-
Horvath TL, Naftolin F, Leranth C. Beta-endorphin innervation of dopamine neurons in the rat hypothalamus: a light and electron microscopic double immunostaining study. Endocrinology. 1992;131(3):1547-55.
-
(1992)
Endocrinology
, vol.131
, Issue.3
, pp. 1547-55
-
-
Horvath, T.L.1
Naftolin, F.2
Leranth, C.3
-
160
-
-
33748540764
-
Leptin receptor signaling in midbrain dopamine neurons regulates feeding
-
DOI 10.1016/j.neuron.2006.08.023, PII S0896627306006453
-
Hommel JD, Trinko R, Sears RM, Georgescu D, Liu ZW, Gao XB, et al. Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron. 2006;51(6):801-10. (Pubitemid 44374908)
-
(2006)
Neuron
, vol.51
, Issue.6
, pp. 801-810
-
-
Hommel, J.D.1
Trinko, R.2
Sears, R.M.3
Georgescu, D.4
Liu, Z.-W.5
Gao, X.-B.6
Thurmon, J.J.7
Marinelli, M.8
DiLeone, R.J.9
-
161
-
-
58149301316
-
Pharmacological targeting of the serotonergic system for the treatment of obesity
-
Garfield AS, Heisler LK. Pharmacological targeting of the serotonergic system for the treatment of obesity. J Physiol. 2009;587(Pt 1):49-60.
-
(2009)
J Physiol
, vol.587
, Issue.PART 1
, pp. 49-60
-
-
Garfield, A.S.1
Heisler, L.K.2
-
162
-
-
56549124437
-
Hypothalamic control of hepatic glucose production and its potential role in insulin resistance
-
Buettner C, Camacho RC. Hypothalamic control of hepatic glucose production and its potential role in insulin resistance. Endocrinol Metab Clin North Am. 2008;37(4):825-40.
-
(2008)
Endocrinol Metab Clin North Am
, vol.37
, Issue.4
, pp. 825-40
-
-
Buettner, C.1
Camacho, R.C.2
-
163
-
-
4344710646
-
Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1- β-D-ribofuranoside, controls muscle glycogen synthesis
-
DOI 10.1210/en.2004-0270
-
Perrin C, Knauf C, Burcelin R. Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, controls muscle glycogen synthesis. Endocrinology. 2004;145(9):4025-33. doi:10.1210/en.2004-0270. (Pubitemid 39120547)
-
(2004)
Endocrinology
, vol.145
, Issue.9
, pp. 4025-4033
-
-
Perrin, C.1
Knauf, C.2
Burcelin, R.3
-
164
-
-
0028200927
-
Regulatory mechanism of the ventromedial hypothalamus in enhancing glucose uptake in skeletal muscles
-
DOI 10.1016/0006-8993(94)91085-5
-
Minokoshi Y, Okano Y, Shimazu T. Regulatory mechanism of the ventromedial hypothalamus in enhancing glucose uptake in skeletal muscles. Brain Res. 1994;649(1-2):343-7. (Pubitemid 24197233)
-
(1994)
Brain Research
, vol.649
, Issue.1-2
, pp. 343-347
-
-
Minokoshi, Y.1
Okano, Y.2
Shimazu, T.3
-
165
-
-
0032971214
-
Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats
-
DOI 10.2337/diabetes.48.2.287
-
Minokoshi Y, Haque MS, Shimazu T. Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats. Diabetes. 1999;48(2):287-91. (Pubitemid 29061100)
-
(1999)
Diabetes
, vol.48
, Issue.2
, pp. 287-291
-
-
Minokoshi, Y.1
Haque, M.S.2
Shimazu, T.3
-
166
-
-
0016695315
-
Effect ofcerebral intraventric-ular insulin on pancreatic insulin secretion in the dog
-
Chen M, Woods SC, Porte Jr D. Effect ofcerebral intraventric-ular insulin on pancreatic insulin secretion in the dog. Diabetes. 1975;24(10):910-4.
-
(1975)
Diabetes
, vol.24
, Issue.10
, pp. 910-4
-
-
Chen, M.1
Woods, S.C.2
Porte Jr., D.3
-
167
-
-
0024995157
-
A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation
-
Sako Y, Grill VE. A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation. Endocrinology 1990;127(4):1580-9. (Pubitemid 20315212)
-
(1990)
Endocrinology
, vol.127
, Issue.4
, pp. 1580-1589
-
-
Sako, Y.1
Grill, V.E.2
-
168
-
-
0028268936
-
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
-
Zhou YP, Grill VE. Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest. 1994;93(2):870-6. doi:10.1172/ JCI117042. (Pubitemid 24072831)
-
(1994)
Journal of Clinical Investigation
, vol.93
, Issue.2
, pp. 870-876
-
-
Zhou, Y.-P.1
Grill, V.E.2
-
169
-
-
0030731946
-
Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels
-
DOI 10.1074/jbc.272.48.30261
-
Gremlich S, Bonny C, Waeber G, Thorens B. Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels. J Biol Chem. 1997;272(48):30261-9. (Pubitemid 27512230)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.48
, pp. 30261-30269
-
-
Gremlich, S.1
Bonny, C.2
Waeber, G.3
Thorens, B.4
-
170
-
-
77953028265
-
Central infusion of leptin improves insulin resistance and suppresses beta-cell function, but not beta-cell mass, primarily through the sympathetic nervous system in a type 2 diabetic rat model
-
Park S, Ahn IS, da Kim S. Central infusion of leptin improves insulin resistance and suppresses beta-cell function, but not beta-cell mass, primarily through the sympathetic nervous system in a type 2 diabetic rat model. Life Sci. 2010;86(23-24):854-62.
-
(2010)
Life Sci
, vol.86
, Issue.23-24
, pp. 854-62
-
-
Park, S.1
Ahn, I.S.2
Da Kim, S.3
-
174
-
-
33846032275
-
Gastrointestinal regulation of food intake
-
DOI 10.1172/JCI30227
-
Cummings DE, Overduin J. Gastrointestinal regulation of food intake. J Clin Invest. 2007;117(1):13-23. doi:10.1172/JCI30227. (Pubitemid 46048445)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 13-23
-
-
Cummings, D.E.1
Overduin, J.2
-
175
-
-
67849124833
-
Intestinal cholecystokinin controls glucose production through a neuronal network
-
Cheung GW, Kokorovic A, Lam CK, Chari M, Lam TK. Intestinal cholecystokinin controls glucose production through a neuronal network. Cell Metab. 2009;10(2):99-109.
-
(2009)
Cell Metab
, vol.10
, Issue.2
, pp. 99-109
-
-
Cheung, G.W.1
Kokorovic, A.2
Lam, C.K.3
Chari, M.4
Lam, T.K.5
-
176
-
-
30944467225
-
Endogenous glucagon-like peptide 1 controls endocrine pancreatic secretion and antro-pyloro-duodenal motility in humans
-
DOI 10.1136/gut.2004.059741
-
Schirra J, Nicolaus M, Roggel R, Katschinski M, Storr M, Woerle HJ, et al. Endogenous glucagon-like peptide 1 controls endocrine pancreatic secretion and antro-pyloro-duodenal motil-ity in humans. Gut. 2006;55(2):243-51. (Pubitemid 43117285)
-
(2006)
Gut
, vol.55
, Issue.2
, pp. 243-251
-
-
Schirra, J.1
Nicolaus, M.2
Roggel, R.3
Katschinski, M.4
Storr, M.5
Woerle, H.J.6
Goke, B.7
-
177
-
-
0023638829
-
Glucagon-like peptide-1 7-36: A physiological incretin in man
-
Kreymann B, Williams G, Ghatei MA, Bloom SR. Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet. 1987;2 (8571):1300-4. (Pubitemid 17156636)
-
(1987)
Lancet
, vol.2
, Issue.8571
, pp. 1300-1304
-
-
Kreymann, B.1
Williams, G.2
Ghatei, M.A.3
Bloom, S.R.4
-
178
-
-
0023107555
-
Insulinotropin: Glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas
-
Mojsov S, Weir GC, Habener JF. Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas. J Clin Invest. 1987;79(2):616-9. doi:10.1172/JCI112855. (Pubitemid 17009701)
-
(1987)
Journal of Clinical Investigation
, vol.79
, Issue.2
, pp. 616-619
-
-
Mojsov, S.1
Weir, G.C.2
Habener, J.F.3
-
180
-
-
77957259261
-
Glucagon-like peptide-1 receptor knockout mice are protected from high-fat diet-induced insulin resistance
-
Ayala JE, Bracy DP, James FD, Burmeister MA, Wasserman DH, Drucker DJ. Glucagon-like peptide-1 receptor knockout mice are protected from high-fat diet-induced insulin resistance. Endocrinology. 2010;151(10):4678-87.
-
(2010)
Endocrinology
, vol.151
, Issue.10
, pp. 4678-87
-
-
Ayala, J.E.1
Bracy, D.P.2
James, F.D.3
Burmeister, M.A.4
Wasserman, D.H.5
Drucker, D.J.6
-
181
-
-
31044456099
-
Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
-
DOI 10.1172/JCI25764
-
Knauf C, Cani PD, Perrin C, Iglesias MA, Maury JF, Bernard E, et al. Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage. J Clin Invest. 2005;115(12):3554-63. doi:10.1172/JCI25764. (Pubitemid 43121843)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.12
, pp. 3554-3563
-
-
Knauf, C.1
Cani, P.D.2
Perrin, C.3
Iglesias, M.A.4
Maury, J.F.5
Bernard, E.6
Benhamed, F.7
Gremeaux, T.8
Drucker, D.J.9
Kahn, C.R.10
Girard, J.11
Tanti, J.F.12
Delzenne, N.M.13
Postic, C.14
Burcelin, R.15
-
182
-
-
77954891541
-
GLP-1 treatment reduces endogenous insulin resistance via activation of central GLP-1 receptors in mice fed a high-fat diet
-
Parlevliet ET, de Leeuw van Weenen JE, Romijn JA, Pijl H. GLP-1 treatment reduces endogenous insulin resistance via activation of central GLP-1 receptors in mice fed a high-fat diet. Am J Physiol Endocrinol Metab. 2010;299(2):E318-24.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
, Issue.2
-
-
Parlevliet, E.T.1
De Leeuw Van Weenen, J.E.2
Romijn, J.A.3
Pijl, H.4
-
183
-
-
0345726358
-
Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites
-
Yamamoto H, Kishi T, Lee CE, Choi BJ, Fang H, Hollenberg AN, et al. Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites. J Neurosci. 2003;23(7):2939-46. (Pubitemid 36418630)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.7
, pp. 2939-2946
-
-
Yamamoto, H.1
Kishi, T.2
Lee, C.E.3
Choi, B.J.4
Fang, H.5
Hollenberg, A.N.6
Drucker, D.J.7
Elmquist, J.K.8
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