Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease

Journal of Neuroscience

Volumn 25, Issue 1, 2005, Pages 184-191

  Andrews, Zane B ^a   Horvath, Balazs ^a   Barnstable, Colin J ^a   Elseworth, John ^a   Yang, Lichuan ^b   Beal, M Flynt ^b   Roth, Robert H ^a   Matthews, Russell T ^a   Horvath, Tamas L ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Mitochondria; MPTP; Parkinson's disease; Reactive oxygen species; Substantia nigra; Uncoupling protein 2

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; FLUORESCENT DYE; HYDROETHIDINE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL METABOLISM; CELL SURVIVAL; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ELECTRON MICROSCOPY; GENE DELETION; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBSTANTIA NIGRA; TRANSGENIC MOUSE; VENTRAL TEGMENTUM; WILD TYPE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; 1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; CELL SURVIVAL; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DOPAMINE; HUMANS; IMMUNOHISTOCHEMISTRY; ION CHANNELS; MALE; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXYGEN CONSUMPTION; PARKINSONIAN DISORDERS; REACTIVE OXYGEN SPECIES; SUBSTANTIA NIGRA;

EID: 12144284373     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4269-04.2005     Document Type: Article

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