The energy landscape analysis of cancer mutations in protein kinases

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Dixit, Anshuman ^a   Verkhivker, Gennady M ^b,c  

^a UNIVERSITY OF KANSAS   (United States)

^b CHAPMAN UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; ALLOSTERISM; ARTICLE; CANCER RESEARCH; COMPUTER SIMULATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EQUILIBRIUM CONSTANT; GENE ACTIVATION; GENE FUNCTION; GENE INACTIVATION; GENE MUTATION; GENE PROBE; GENE SWITCHING; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MUTATIONAL ANALYSIS; ONCOGENE; ONCOGENE BRAF; ONCOGENE BTK; ONCOGENE EGFR; ONCOGENE KIT; ONCOGENE MET; ONCOGENE RET; PROTEIN KINASE GENE; SIGNAL TRANSDUCTION; STRUCTURAL BIOINFORMATICS; THERMODYNAMICS; TUMOR GENE; BIOLOGY; CHEMISTRY; ENERGY METABOLISM; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MUTATION; NEOPLASM; PATHOLOGY; PROTEIN CONFORMATION;

PROTEIN KINASE;

ALLOSTERIC REGULATION; CATALYTIC DOMAIN; COMPUTATIONAL BIOLOGY; ENERGY METABOLISM; HUMANS; MOLECULAR DYNAMICS SIMULATION; MUTATION; NEOPLASMS; ONCOGENES; PROTEIN CONFORMATION; PROTEIN KINASES;

EID: 80053588204     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026071     Document Type: Article

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