Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 47, 2006, Pages 17783-17788

  Kornev, Alexandr P ^a   Haste, Nina M ^b   Taylor, Susan S ^b   Ten Eyck, Lynn F ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Graph theory; Protein surface

Indexed keywords

ASPARTIC ACID; GLYCINE; PHENYLALANINE; PHOSPHATE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE;

ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME ACTIVITY; HYDROPHOBICITY; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION;

ALGORITHMS; AMINO ACID SEQUENCE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIN-DEPENDENT KINASE 2; ENZYME ACTIVATION; HUMANS; HYDROPHOBICITY; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY;

EUKARYOTA; PROKARYOTA;

EID: 33845197964     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0607656103     Document Type: Article

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