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Volumn 289, Issue 5486, 2000, Pages 1938-1942
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Structural mechanism for STI-571 inhibition of Abelson tyrosine kinase
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Author keywords
[No Author keywords available]
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Indexed keywords
IMATINIB;
PROTEIN TYROSINE KINASE;
PROTEIN TYROSINE KINASE INHIBITOR;
UNCLASSIFIED DRUG;
VIRUS ENZYME;
ABELSON MURINE LEUKEMIA ONCOVIRUS;
ARTICLE;
BINDING AFFINITY;
CHRONIC MYELOID LEUKEMIA;
CRYSTAL STRUCTURE;
DRUG BINDING;
DRUG STRUCTURE;
ENZYME ACTIVATION;
ENZYME CONFORMATION;
ENZYME SPECIFICITY;
HUMAN;
PRIORITY JOURNAL;
ANIMALS;
ANTINEOPLASTIC AGENTS;
CATALYTIC DOMAIN;
CRYSTALLOGRAPHY, X-RAY;
ENZYME ACTIVATION;
ENZYME INHIBITORS;
HUMANS;
MICE;
MODELS, MOLECULAR;
PHOSPHORYLATION;
PIPERAZINES;
PROTEIN CONFORMATION;
PROTO-ONCOGENE PROTEINS C-ABL;
PYRIMIDINES;
RECOMBINANT FUSION PROTEINS;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 0034665713
PISSN: 00368075
EISSN: None
Source Type: Journal
DOI: 10.1126/science.289.5486.1938 Document Type: Article |
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Times cited : (1677)
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References (34)
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