Mapping the conformational transition in Src activation by cumulating the information from multiple molecular dynamics trajectories

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 10, 2009, Pages 3776-3781

  Yang, Sichun ^a   Banavali, Nilesh K ^b   Roux, Benoît ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b WADSWORTH CENTER   (United States)

Author keywords

Conformational landscape; Connectivity map; Intermediate; Kinase inhibitor

Indexed keywords

HEMATOPOIETIC CELL KINASE; PROTEIN TYROSINE KINASE;

ALLOSTERISM; ARTICLE; CATALYSIS; CELL GROWTH; CELL PROLIFERATION; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; GENE MAPPING; HYDROPHOBICITY; MATHEMATICAL COMPUTING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

ENZYME ACTIVATION; HYDROPHOBICITY; IONS; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; SRC-FAMILY KINASES;

EID: 62649161772     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0808261106     Document Type: Article

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