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Volumn 71, Issue 3, 2011, Pages 1103-1114

EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 8; GROWTH FACTOR RECEPTOR; PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 79551510855     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-2384     Document Type: Article
Times cited : (232)

References (49)
  • 1
    • 33847718214 scopus 로고    scopus 로고
    • The EGF receptor family: Spearheading a merger of signaling and therapeutics
    • DOI 10.1016/j.ceb.2007.02.008, PII S0955067407000221
    • Bublil EM, Yarden Y. The EGF receptor family: spearheading a merger of signaling and therapeutics. Curr Opin Cell Biol 2007;19:124-34. (Pubitemid 46386405)
    • (2007) Current Opinion in Cell Biology , vol.19 , Issue.2 , pp. 124-134
    • Bublil, E.M.1    Yarden, Y.2
  • 2
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2000;103:211-25.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 4
    • 28444453967 scopus 로고    scopus 로고
    • Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity
    • DOI 10.1016/j.radonc.2005.06.022, PII S0167814005002513
    • Dittmann K, Mayer C, Rodemann HP. Inhibition of radiation-induced EGFR nuclear import by C225 (cetuximab) suppresses DNA-PK activity. Radiother Oncol 2005;76:157-61. (Pubitemid 41725442)
    • (2005) Radiotherapy and Oncology , vol.76 , Issue.2 , pp. 157-161
    • Dittmann, K.1    Mayer, C.2    Rodemann, H.-P.3
  • 5
    • 70350653741 scopus 로고    scopus 로고
    • Nuclear EGFR contributes to acquired resistance to cetuximab
    • Li C, Iida M, Dunn EF, Ghia AJ, Wheeler DL. Nuclear EGFR contributes to acquired resistance to cetuximab. Oncogene 2009;28:3801-13.
    • (2009) Oncogene , vol.28 , pp. 3801-3813
    • Li, C.1    Iida, M.2    Dunn, E.F.3    Ghia, A.J.4    Wheeler, D.L.5
  • 6
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497-500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3    Tracy, S.4    Greulich, H.5    Gabriel, S.6
  • 7
    • 0012381722 scopus 로고    scopus 로고
    • Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial)
    • corrected
    • Fukuoka M, Yano S, Giaccone G, Tamura T, Nakagawa K, Douillard JY, et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. J Clin Oncol 2003;21:2237-46.
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3    Tamura, T.4    Nakagawa, K.5    Douillard, J.Y.6
  • 8
    • 0036690404 scopus 로고    scopus 로고
    • Effects of the epidermal growth factor receptor inhibitor OSI-774, Tarceva, on downstream signaling pathways and apoptosis in human pancreatic adenocarcinoma
    • Ng SS, Tsao MS, Nicklee T, Hedley DW. Effects of the epidermal growth factor receptor inhibitor OSI-774, Tarceva, on downstream signaling pathways and apoptosis in human pancreatic adenocarcinoma. Mol Cancer Ther 2002;1:777-83.
    • (2002) Mol Cancer Ther , vol.1 , pp. 777-783
    • Ng, S.S.1    Tsao, M.S.2    Nicklee, T.3    Hedley, D.W.4
  • 9
    • 0034329308 scopus 로고    scopus 로고
    • Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers
    • Bonner JA, Raisch KP, Trummell HQ, Robert F, Meredith RF, Spencer SA, et al. Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers. J Clin Oncol 2000;18:47S-53S.
    • (2000) J Clin Oncol , vol.18
    • Bonner, J.A.1    Raisch, K.P.2    Trummell, H.Q.3    Robert, F.4    Meredith, R.F.5    Spencer, S.A.6
  • 10
    • 0035409904 scopus 로고    scopus 로고
    • IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer
    • Herbst RS, Kim ES, Harari PM. IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer. Expert Opin Biol Ther 2001;1:719-32.
    • (2001) Expert Opin Biol Ther , vol.1 , pp. 719-732
    • Herbst, R.S.1    Kim, E.S.2    Harari, P.M.3
  • 11
    • 5144220297 scopus 로고    scopus 로고
    • Modulation of DNA repair in vitro after treatment with chemotherapeutic agents by the epidermal growth factor receptor inhibitor Gefitinib (ZD1839)
    • DOI 10.1158/1078-0432.CCR-04-0586
    • Friedmann B, Caplin M, Hartley JA, Hochhauser D. Modulation of DNA repair in vitro after treatment with chemotherapeutic agents by the epidermal growth factor receptor inhibitor gefitinib (ZD1839). Clin Cancer Res 2004;10:6476-86. (Pubitemid 39346543)
    • (2004) Clinical Cancer Research , vol.10 , Issue.19 , pp. 6476-6486
    • Friedmann, B.1    Caplin, M.2    Hartley, J.A.3    Hochhauser, D.4
  • 12
    • 36849032852 scopus 로고    scopus 로고
    • Radiation-induced EGFR-signaling and control of DNA-damage repair
    • Rodemann HP, Dittmann K, Toulany M. Radiation-induced EGFR-signaling and control of DNA-damage repair. Int J Radiat Biol 2007;83:781-91.
    • (2007) Int J Radiat Biol , vol.83 , pp. 781-791
    • Rodemann, H.P.1    Dittmann, K.2    Toulany, M.3
  • 13
    • 70350741359 scopus 로고    scopus 로고
    • Nuclear translocation of the epidermal growth factor receptor family membrane tyrosine kinase receptors
    • Wang SC, Hung MC. Nuclear translocation of the epidermal growth factor receptor family membrane tyrosine kinase receptors. Clin Cancer Res 2009;15:6484-9.
    • (2009) Clin Cancer Res , vol.15 , pp. 6484-6489
    • Wang, S.C.1    Hung, M.C.2
  • 14
    • 36849048584 scopus 로고    scopus 로고
    • Nuclear EGFR signalling network in cancers: Linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival
    • Lo HW, Hung MC. Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival. Br J Cancer 2007;96Suppl:R16-20.
    • (2007) Br J Cancer , vol.96 , Issue.SUPPL.
    • Lo, H.W.1    Hung, M.C.2
  • 15
    • 0033372557 scopus 로고    scopus 로고
    • Combination of EGFR, HER-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members
    • Xia W, Lau YK, Zhang HZ, Xiao FY, Johnston DA, Liu AR, et al. Combination of EGFR, HER-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members. Clin Cancer Res 1999;5:4164-74.
    • (1999) Clin Cancer Res , vol.5 , pp. 4164-4174
    • Xia, W.1    Lau, Y.K.2    Zhang, H.Z.3    Xiao, F.Y.4    Johnston, D.A.5    Liu, A.R.6
  • 16
    • 77649272555 scopus 로고    scopus 로고
    • Nuclear EGFR in ductal invasive breast cancer: Correlation with cyclin-D1 and prognosis
    • Hadzisejdic I, Mustac E, Jonjic N, Petkovic M, Grahovac B. Nuclear EGFR in ductal invasive breast cancer: correlation with cyclin-D1 and prognosis. Mod Pathol 2010;23:392-403.
    • (2010) Mod Pathol , vol.23 , pp. 392-403
    • Hadzisejdic, I.1    Mustac, E.2    Jonjic, N.3    Petkovic, M.4    Grahovac, B.5
  • 17
    • 77249132723 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes
    • Lo HW, Cao X, Zhu H, Ali-Osman F. Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes. Mol Cancer Res 2010;8:232-45.
    • (2010) Mol Cancer Res , vol.8 , pp. 232-245
    • Lo, H.W.1    Cao, X.2    Zhu, H.3    Ali-Osman, F.4
  • 18
    • 67649225203 scopus 로고    scopus 로고
    • Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer
    • Xia W, Wei Y, Du Y, Liu J, Chang B, Yu YL, et al. Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer. Mol Carcinog 2009;48:610-7.
    • (2009) Mol Carcinog , vol.48 , pp. 610-617
    • Xia, W.1    Wei, Y.2    Du, Y.3    Liu, J.4    Chang, B.5    Yu, Y.L.6
  • 19
    • 21244446728 scopus 로고    scopus 로고
    • A structural model for the membrane-bound form of the juxtamembrane domain of the epidermal growth factor receptor
    • Choowongkomon K, Carlin CR, Sonnichsen FD. A structural model for the membrane-bound form of the juxtamembrane domain of the epidermal growth factor receptor. J Biol Chem 2005;280:24043-52.
    • (2005) J Biol Chem , vol.280 , pp. 24043-24052
    • Choowongkomon, K.1    Carlin, C.R.2    Sonnichsen, F.D.3
  • 20
    • 0037064048 scopus 로고    scopus 로고
    • The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core
    • DOI 10.1074/jbc.M104646200
    • He C, Hobert M, Friend L, Carlin C. The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core. J Biol Chem 2002;277:38284-93. (Pubitemid 35157769)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.41 , pp. 38284-38293
    • He, C.1    Hobert, M.2    Friend, L.3    Carlin, C.4
  • 21
    • 0034714277 scopus 로고    scopus 로고
    • Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome
    • Bao J, Alroy I, Waterman H, Schejter ED, Brodie C, Gruenberg J, et al. Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome. J Biol Chem 2000;275:26178-86.
    • (2000) J Biol Chem , vol.275 , pp. 26178-26186
    • Bao, J.1    Alroy, I.2    Waterman, H.3    Schejter, E.D.4    Brodie, C.5    Gruenberg, J.6
  • 22
    • 34249845380 scopus 로고    scopus 로고
    • Characterization of a novel tripartite nuclear localization sequence in the EGFR family
    • Hsu SC, Hung MC. Characterization of a novel tripartite nuclear localization sequence in the EGFR family. J Biol Chem 2007;282:10432-40.
    • (2007) J Biol Chem , vol.282 , pp. 10432-10440
    • Hsu, S.C.1    Hung, M.C.2
  • 23
    • 77953442037 scopus 로고    scopus 로고
    • Nuclear EGFR is required for cisplatin resistance and DNA repair
    • Hsu SC, Miller SA, Wang Y, Hung MC. Nuclear EGFR is required for cisplatin resistance and DNA repair. Am J Transl Res 2009;1:249-58.
    • (2009) Am J Transl Res , vol.1 , pp. 249-258
    • Hsu, S.C.1    Miller, S.A.2    Wang, Y.3    Hung, M.C.4
  • 24
    • 23844471971 scopus 로고    scopus 로고
    • Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface
    • Dawson JP, Berger MB, Lin CC, Schlessinger J, Lemmon MA, Ferguson KM. Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface. Mol Cell Biol 2005;25:7734-42.
    • (2005) Mol Cell Biol , vol.25 , pp. 7734-7742
    • Dawson, J.P.1    Berger, M.B.2    Lin, C.C.3    Schlessinger, J.4    Lemmon, M.A.5    Ferguson, K.M.6
  • 25
    • 67549144420 scopus 로고    scopus 로고
    • The juxtamembrane region of EGFR takes center stage
    • Hubbard SR. The juxtamembrane region of EGFR takes center stage. Cell 2009;137:1181-3.
    • (2009) Cell , vol.137 , pp. 1181-1183
    • Hubbard, S.R.1
  • 26
    • 34347223656 scopus 로고    scopus 로고
    • Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma
    • Das AK, Chen BP, Story MD, Sato M, Minna JD, Chen DJ, et al. Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma. Cancer Res 2007;67:5267-74.
    • (2007) Cancer Res , vol.67 , pp. 5267-5274
    • Das, A.K.1    Chen, B.P.2    Story, M.D.3    Sato, M.4    Minna, J.D.5    Chen, D.J.6
  • 27
    • 70949095656 scopus 로고    scopus 로고
    • Involvement of the HER2 pathway in repair of DNA damage produced by chemotherapeutic agents
    • Boone JJ, Bhosle J, Tilby MJ, Hartley JA, Hochhauser D. Involvement of the HER2 pathway in repair of DNA damage produced by chemotherapeutic agents. Mol Cancer Ther 2009;8:3015-23.
    • (2009) Mol Cancer Ther , vol.8 , pp. 3015-3023
    • Boone, J.J.1    Bhosle, J.2    Tilby, M.J.3    Hartley, J.A.4    Hochhauser, D.5
  • 29
    • 33744521546 scopus 로고    scopus 로고
    • Characterization of interactions between ras family GTPases and their effectors
    • Rodriguez-Viciana P, McCormick F. Characterization of interactions between ras family GTPases and their effectors. Methods Enzymol 2006;407:187-94.
    • (2006) Methods Enzymol , vol.407 , pp. 187-194
    • Rodriguez-Viciana, P.1    McCormick, F.2
  • 30
    • 77954759289 scopus 로고    scopus 로고
    • Nuclear trafficking of the epidermal growth factor receptor family membrane proteins
    • Wang YN, Yamaguchi H, Hsu JM, Hung MC. Nuclear trafficking of the epidermal growth factor receptor family membrane proteins. Oncogene 2010;29:3997-4006.
    • (2010) Oncogene , vol.29 , pp. 3997-4006
    • Wang, Y.N.1    Yamaguchi, H.2    Hsu, J.M.3    Hung, M.C.4
  • 31
    • 33644987412 scopus 로고    scopus 로고
    • Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment
    • Friedmann BJ, Caplin M, Savic B, Shah T, Lord CJ, Ashworth A, et al. Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment. Mol Cancer Ther 2006;5:209-18.
    • (2006) Mol Cancer Ther , vol.5 , pp. 209-218
    • Friedmann, B.J.1    Caplin, M.2    Savic, B.3    Shah, T.4    Lord, C.J.5    Ashworth, A.6
  • 32
    • 52749092194 scopus 로고    scopus 로고
    • Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK
    • Dittmann K, Mayer C, Kehlbach R, Rodemann HP. Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK. Mol Cancer 2008;7:69.
    • (2008) Mol Cancer , vol.7 , pp. 69
    • Dittmann, K.1    Mayer, C.2    Kehlbach, R.3    Rodemann, H.P.4
  • 33
    • 33947118714 scopus 로고    scopus 로고
    • Role of the Sec61 translocation in EGF receptor trafficking to the nucleus and gene expression
    • Liao HJ, Carpenter G. Role of the Sec61 translocation in EGF receptor trafficking to the nucleus and gene expression. Mol Biol Cell 2007;18:1064-72.
    • (2007) Mol Biol Cell , vol.18 , pp. 1064-1072
    • Liao, H.J.1    Carpenter, G.2
  • 34
    • 67549145398 scopus 로고    scopus 로고
    • Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment
    • Jura N, Endres NF, Engel K, Deindl S, Das R, Lamers MH, et al. Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell 2009;137:1293-307.
    • (2009) Cell , vol.137 , pp. 1293-1307
    • Jura, N.1    Endres, N.F.2    Engel, K.3    Deindl, S.4    Das, R.5    Lamers, M.H.6
  • 35
    • 34948880694 scopus 로고    scopus 로고
    • Enhanced repair of DNA interstrand crosslinking in ovarian cancer cells from patients following treatment with platinum-based chemotherapy
    • DOI 10.1038/sj.bjc.6603973, PII 6603973
    • Wynne P, Newton C, Ledermann JA, Olaitan A, Mould TA, Hartley JA. Enhanced repair of DNA interstrand crosslinking in ovarian cancer cells from patients following treatment with platinum-based chemotherapy. Br J Cancer 2007;97:927-33. (Pubitemid 47519316)
    • (2007) British Journal of Cancer , vol.97 , Issue.7 , pp. 927-933
    • Wynne, P.1    Newton, C.2    Ledermann, J.A.3    Olaitan, A.4    Mould, T.A.5    Hartley, J.A.6
  • 36
    • 0141974936 scopus 로고    scopus 로고
    • Vanillins-a novel family of DNA-PK inhibitors
    • Durant S, Karran P. Vanillins-a novel family of DNA-PK inhibitors. Nucleic Acids Res 2003;31:5501-12.
    • (2003) Nucleic Acids Res , vol.31 , pp. 5501-5512
    • Durant, S.1    Karran, P.2
  • 37
    • 24744449739 scopus 로고    scopus 로고
    • Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase
    • Dittmann K, Mayer C, Fehrenbacher B, Schaller M, Raju U, Milas L, et al. Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J Biol Chem 2005;280:31182-9.
    • (2005) J Biol Chem , vol.280 , pp. 31182-31189
    • Dittmann, K.1    Mayer, C.2    Fehrenbacher, B.3    Schaller, M.4    Raju, U.5    Milas, L.6
  • 39
    • 4143053880 scopus 로고    scopus 로고
    • Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation
    • DOI 10.1074/jbc.M404936200
    • Feng J, Tamaskovic R, Yang Z, Brazil DP, Merlo A, Hess D, et al. Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation. J Biol Chem 2004;279:35510-7. (Pubitemid 39100551)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.34 , pp. 35510-35517
    • Feng, J.1    Tamaskovic, R.2    Yang, Z.3    Brazil, D.P.4    Merlo, A.5    Hess, D.6    Hemmings, B.A.7
  • 40
    • 51049105757 scopus 로고    scopus 로고
    • Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair
    • Toulany M, Kehlbach R, Florczak U, Sak A, Wang S, Chen J, et al. Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair. Mol Cancer Ther 2008;7:1772-81.
    • (2008) Mol Cancer Ther , vol.7 , pp. 1772-1781
    • Toulany, M.1    Kehlbach, R.2    Florczak, U.3    Sak, A.4    Wang, S.5    Chen, J.6
  • 42
    • 66249149058 scopus 로고    scopus 로고
    • EGFRvIII and DNA double-strand break repair: A molecular mechanism for radioresistance in glioblastoma
    • Mukherjee B, McEllin B, Camacho CV, Tomimatsu N, Sirasanagandala S, Nannepaga S, et al. EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma. Cancer Res 2009;69:4252-9.
    • (2009) Cancer Res , vol.69 , pp. 4252-4259
    • Mukherjee, B.1    McEllin, B.2    Camacho, C.V.3    Tomimatsu, N.4    Sirasanagandala, S.5    Nannepaga, S.6
  • 43
    • 33750339641 scopus 로고    scopus 로고
    • Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation
    • Das AK, Sato M, Story MD, Peyton M, Graves R, Redpath S, et al. Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation. Cancer Res 2006;66:9601-8.
    • (2006) Cancer Res , vol.66 , pp. 9601-9608
    • Das, A.K.1    Sato, M.2    Story, M.D.3    Peyton, M.4    Graves, R.5    Redpath, S.6
  • 44
    • 36749054018 scopus 로고    scopus 로고
    • Ligand-independent phosphorylation of Y869 (Y845) links mutant EGFR signaling to stat-mediated gene expression
    • Yang S, Park K, Turkson J, Arteaga CL. Ligand-independent phosphorylation of Y869 (Y845) links mutant EGFR signaling to stat-mediated gene expression. Exp Cell Res 2008;314:413-9.
    • (2008) Exp Cell Res , Issue.314 , pp. 413-419
    • Yang, S.1    Park, K.2    Turkson, J.3    Arteaga, C.L.4
  • 45
    • 70149117469 scopus 로고    scopus 로고
    • Hierarchical modeling of activation mechanisms in the ABL and EGFR kinase domains: Thermodynamic and mechanistic catalysts of kinase activation by cancer mutations
    • Dixit A, Verkhivker GM. Hierarchical modeling of activation mechanisms in the ABL and EGFR kinase domains: thermodynamic and mechanistic catalysts of kinase activation by cancer mutations. PLoS Comput Biol 2009;5:e1000487.
    • (2009) PLoS Comput Biol , vol.5
    • Dixit, A.1    Verkhivker, G.M.2
  • 46
    • 77950819843 scopus 로고    scopus 로고
    • Role of epidermal growth factor receptor degradation in cisplatin- induced cytotoxicity in head and neck cancer
    • Ahsan A, Hiniker SM, Ramanand SG, Nyati S, Hegde A, Helman A, et al. Role of epidermal growth factor receptor degradation in cisplatin- induced cytotoxicity in head and neck cancer. Cancer Res 2010;70:2862-9.
    • (2010) Cancer Res , vol.70 , pp. 2862-2869
    • Ahsan, A.1    Hiniker, S.M.2    Ramanand, S.G.3    Nyati, S.4    Hegde, A.5    Helman, A.6
  • 47
    • 0031891006 scopus 로고    scopus 로고
    • Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells
    • Bandyopadhyay D, Mandal M, Adam L, Mendelsohn J, Kumar R. Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells. J Biol Chem 1998;273:1568-73.
    • (1998) J Biol Chem , vol.273 , pp. 1568-1573
    • Bandyopadhyay, D.1    Mandal, M.2    Adam, L.3    Mendelsohn, J.4    Kumar, R.5
  • 48
    • 42949165854 scopus 로고    scopus 로고
    • PKBalpha/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival
    • DOI 10.1016/j.molcel.2008.02.024, PII S1097276508001718
    • Bozulic L, Surucu B, Hynx D, Hemmings BA. PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival. Mol Cell 2008;30:203-13. (Pubitemid 351626686)
    • (2008) Molecular Cell , vol.30 , Issue.2 , pp. 203-213
    • Bozulic, L.1    Surucu, B.2    Hynx, D.3    Hemmings, B.A.4
  • 49
    • 33747356750 scopus 로고    scopus 로고
    • Protein kinase Cepsilon activates protein kinase B/Akt via DNA-PK to protect against tumor necrosis factor-alpha- induced cell death
    • Lu D, Huang J, Basu A. Protein kinase Cepsilon activates protein kinase B/Akt via DNA-PK to protect against tumor necrosis factor-alpha- induced cell death. J Biol Chem 2006;281:22799-807.
    • (2006) J Biol Chem , vol.281 , pp. 22799-22807
    • Lu, D.1    Huang, J.2    Basu, A.3


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