Activation of adenylate kinase by denaturants is due to the increasing conformational flexibility at its active sites

Biochemical and Biophysical Research Communications

Volumn 238, Issue 2, 1997, Pages 382-386

  Zhang, Hong Jie ^a   Sheng, Xiang Rong ^a   Pan, Xian Ming ^a   Zhou, Jun Mei ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

Author keywords

Activation; Active sites; Adenylate kinase; ANS fluorescence; Conformational flexibility; Denaturants

Indexed keywords

8 ANILINO 1 NAPHTHALENESULFONIC ACID; ADENYLATE KINASE; UREA;

ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME CONFORMATION; ENZYME DENATURATION; ENZYME KINETICS; FLUORESCENCE; PRIORITY JOURNAL;

EID: 0031577566     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1997.7301     Document Type: Article

References (19)

1. Tsou C. L. Trends Biochem. Sci. 11:1986;427-429.
2. Tsou C. L. Science. 262:1993;380-381.
3. Tsou C. L. Biochem. Biophys. Acta. 1253:1995;151-162.
4. Fan Y. X., Ju M., Zhou J. M., Tsou C. L. Biochem J. 315:1996;97-102.
5. Noda L. Enzymes. 1973;Academic Press, New York. p. 279-305.
6. Hamada M., Takenaka H., Sumida M., Kuby S. A. Kuby S. A. A Study of Enzymes. 1992;403-444 CRC Press, Boca Raton.
7. Schulz G. E., Müller C. W., Diederichs K. J. Mol. Biol. 213:1990;627-630.
8. Zhang Y. L., Zhou J. M., Tsou C. L. Biochem. Biophys. Acta. 1164:1993;61-67.
9. Eftink M. R. Biophys J. 66:1994;482-501.
10. Pai E. F., Sachsenheimer W., Schirmer R. H., Schulz G. E. J. Mol. Biol. 114:1977;37-45.
11. Müller C. W., Schulz G. E. J. Mol. Biol. 224:1992;159-177.
12. Zhang Y. L., Zhou J. M., Tsou C. L. Biochem. Biophys. Acta. 1295:1996;239-244.
13. Kumar T. K. S., Jayaraman G., Lin W.-Y., Yu C. Biochem. Biophys. Acta. 1294:1996;103-105.
14. Gerstein M., Schulz G., Chothia C. J. Mol. Biol. 229:1993;494-501.
15. Vonrhein C., Schlauderer G. J., Schulz G. E. Structure. 3:1995;483-490.
16. Schlauderer G. J., Proba K., Schulz G. E. J. Mol. Biol. 256:1996;223-227.
17. Dreusicke D., Schultz G. E. J. Mol. Biol. 203:1988;1021-1028.
18. Conner J., Russell P. J. Biochemical and Biophysical Research Communications. 113:1983;348-352.
19. Sinev M. A., Sineva E. V., Ittah V., Haas E. Biochemistry. 35:1996;6425-6437.