Multiple-basin energy landscapes for large-amplitude conformational motions of proteins: Structure-based molecular dynamics simulations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 32, 2006, Pages 11844-11849

  Okazaki, Kei Ichi ^a   Koga, Nobuyasu ^a   Takada, Shoji ^a,b   Onuchic, Jose N ^c   Wolynes, Peter G ^c  

^a KOBE UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Conformational transition; Cracking; Funnel; Partial unfolding

Indexed keywords

BINDING PROTEIN; DIHYDROFOLATE REDUCTASE; GLUTAMINE;

ARTICLE; BIOMOLECULAR ELECTRONICS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTALLOGRAPHY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; SIMULATION; STRUCTURE ANALYSIS;

CARRIER PROTEINS; CELL CYCLE PROTEINS; COMPUTER SIMULATION; ESCHERICHIA COLI; HIV PROTEASE; HUMANS; MODELS, THEORETICAL; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DENATURATION; S100 PROTEINS; TETRAHYDROFOLATE DEHYDROGENASE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 33747065536     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0604375103     Document Type: Article

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