-
1
-
-
6344219895
-
Is allostery an intrinsic property of all dynamic proteins?
-
10.1002/prot.20232 15382234
-
Gunasekaran K Ma B Nussinov R Is allostery an intrinsic property of all dynamic proteins? Proteins 2004 57 4330-443 10.1002/prot.20232 15382234
-
(2004)
Proteins
, vol.57
, pp. 433-443
-
-
Gunasekaran, K.1
Ma, B.2
Nussinov, R.3
-
2
-
-
20344370764
-
Allosteric mechanisms of signal transduction
-
10.1126/science.1108595 15933191
-
Changeux JP Edelstein SJ Allosteric mechanisms of signal transduction. Science 2005 308 1424-1428 10.1126/science.1108595 15933191
-
(2005)
Science
, vol.308
, pp. 1424-1428
-
-
Changeux, J.P.1
Edelstein, S.J.2
-
3
-
-
0041806720
-
Myoglobin: The hydrogen atom of biology and a paradigm of complexity
-
166357 12861080 10.1073/pnas.1633688100
-
Frauenfelder H McMahon BH Fenimore PW Myoglobin: The hydrogen atom of biology and a paradigm of complexity. Proc Natl Acad Sci USA 2003 100 8615-8617 166357 12861080 10.1073/pnas.1633688100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8615-8617
-
-
Frauenfelder, H.1
McMahon, B.H.2
Fenimore, P.W.3
-
4
-
-
0141792364
-
Allosteric changes in protein structure computed by a simple mechanical model: Hemoglobin T↔R2 transition
-
10.1016/j.jmb.2003.08.027 14516750
-
Xu C Tobi D Bahar I Allosteric changes in protein structure computed by a simple mechanical model: Hemoglobin T↔R2 transition. J Mol Biol 2003 333 153-168 10.1016/j.jmb.2003.08.027 14516750
-
(2003)
J Mol Biol
, vol.333
, pp. 153-168
-
-
Xu, C.1
Tobi, D.2
Bahar, I.3
-
5
-
-
33748442882
-
Coupling of global and local vibrational modes in dynamic allostery of proteins
-
10.1529/biophysj.106.082180 16798805
-
Hawkins RH McLeish TCB Coupling of global and local vibrational modes in dynamic allostery of proteins. Biophys J 2006 91 2055-2062 10.1529/ biophysj.106.082180 16798805
-
(2006)
Biophys J
, vol.91
, pp. 2055-2062
-
-
Hawkins, R.H.1
McLeish, T.C.B.2
-
6
-
-
78651189765
-
On the nature of allosteric transitions: A plausible model
-
14343300
-
Monod J Wyman J Changeux JP On the nature of allosteric transitions: A plausible model. J Mol Biol 1965 12 88-118 14343300
-
(1965)
J Mol Biol
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
7
-
-
32344434479
-
The changing landscape of protein allostery
-
10.1016/j.sbi.2006.01.003 16423525
-
Swain JF Gierasch LM The changing landscape of protein allostery. Curr Opin Struct Biol 2006 16 102-108 10.1016/j.sbi.2006.01.003 16423525
-
(2006)
Curr Opin Struct Biol
, vol.16
, pp. 102-108
-
-
Swain, J.F.1
Gierasch, L.M.2
-
8
-
-
0346220393
-
The role of dynamics in allosteric regulation
-
10.1016/j.sbi.2003.10.008 14675554
-
Kern D Zuiderweg ERP The role of dynamics in allosteric regulation. Curr Opin Struct Biol 2003 13 748-757 10.1016/j.sbi.2003.10.008 14675554
-
(2003)
Curr Opin Struct Biol
, vol.13
, pp. 748-757
-
-
Kern, D.1
Zuiderweg, E.R.P.2
-
10
-
-
0031058827
-
Detection of changes in pairwise interactions during allosteric transitions: Coupling between local and global conformational changes in GroEL
-
19979 9050841 10.1073/pnas.94.5.1698
-
Aharoni A Horovitz A Detection of changes in pairwise interactions during allosteric transitions: Coupling between local and global conformational changes in GroEL. Proc Natl Acad Sci USA 1997 94 1698-1702 19979 9050841 10.1073/pnas.94.5.1698
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1698-1702
-
-
Aharoni, A.1
Horovitz, A.2
-
11
-
-
0036721218
-
Mapping pathways of allosteric communication in GroEl by analysis of correlated mutations
-
10.1002/prot.10180 12211028
-
Kass I Horovitz A Mapping pathways of allosteric communication in GroEl by analysis of correlated mutations. Proteins 2002 48 611-617 10.1002/ prot.10180 12211028
-
(2002)
Proteins
, vol.48
, pp. 611-617
-
-
Kass, I.1
Horovitz, A.2
-
12
-
-
2442498470
-
On evolutionary conservation of thermodynamic coupling in proteins
-
10.1074/jbc.M402560200 15023994
-
Fodor AA Aldrich RW On evolutionary conservation of thermodynamic coupling in proteins. J Biol Chem 2004 279 19046-19050 10.1074/ jbc.M402560200 15023994
-
(2004)
J Biol Chem
, vol.279
, pp. 19046-19050
-
-
Fodor, A.A.1
Aldrich, R.W.2
-
13
-
-
33745461893
-
Residues crucial formaintaining short paths in network communication mediate signaling in proteins
-
2006.0019 doi:10.1038/msb4100063 1681495 16738564 10.1038/msb4100063
-
del Sol A Fujihashi H Amoros D Nussinov R Residues crucial formaintaining short paths in network communication mediate signaling in proteins. Mol Syst Biol 2006 2 2006.0019 doi:10.1038/msb4100063 1681495 16738564 10.1038/msb4100063
-
(2006)
Mol Syst Biol
, vol.2
-
-
del Sol, A.1
Fujihashi, H.2
Amoros, D.3
Nussinov, R.4
-
14
-
-
0033536602
-
Evolutionarily conserved pathways of energetic connectivity in protein families
-
10.1126/science.286.5438.295 10514373
-
Lockless SW Ranganathan R Evolutionarily conserved pathways of energetic connectivity in protein families. Science 1999 286 295-299 10.1126/ science.286.5438.295 10514373
-
(1999)
Science
, vol.286
, pp. 295-299
-
-
Lockless, S.W.1
Ranganathan, R.2
-
15
-
-
0037219686
-
Evolutionary conserved networks of residues mediate allosteric communication in proteins
-
10.1038/nsb881
-
Süel GM Lockless SW Wall MA Ranganathan R Evolutionary conserved networks of residues mediate allosteric communication in proteins. Nat Struct Biol 2002 10 59-69 10.1038/nsb881
-
(2002)
Nat Struct Biol
, vol.10
, pp. 59-69
-
-
Süel, G.M.1
Lockless, S.W.2
Wall, M.A.3
Ranganathan, R.4
-
16
-
-
0036468436
-
The modular logic of signaling proteins: Building allosteric switches from simple binding domains
-
10.1016/S0959-440X(02)00290-7 11839491
-
Lim WA The modular logic of signaling proteins: Building allosteric switches from simple binding domains. Curr Opin Struct Biol 2002 12 61-68 10.1016/S0959-440X(02)00290-7 11839491
-
(2002)
Curr Opin Struct Biol
, vol.12
, pp. 61-68
-
-
Lim, W.A.1
-
17
-
-
0141757323
-
Reprogramming control of an allosteric signaling switch trough modular recombination
-
10.1126/science.1085945 14512628
-
Dueber JE Yeh BJ Chak K Lim WA Reprogramming control of an allosteric signaling switch trough modular recombination. Science 2003 301 1904-1908 10.1126/science.1085945 14512628
-
(2003)
Science
, vol.301
, pp. 1904-1908
-
-
Dueber, J.E.1
Yeh, B.J.2
Chak, K.3
Lim, W.A.4
-
18
-
-
9944220618
-
Rewiring cell signaling: The logic and plasticity of eukaryotic protein circuitry
-
10.1016/j.sbi.2004.10.004 15582393
-
Dueber JE Yeh BJ Bhattacharyya RP Lim WA Rewiring cell signaling: The logic and plasticity of eukaryotic protein circuitry. Curr Opin Struct Biol 2004 14 690-699 10.1016/j.sbi.2004.10.004 15582393
-
(2004)
Curr Opin Struct Biol
, vol.14
, pp. 690-699
-
-
Dueber, J.E.1
Yeh, B.J.2
Bhattacharyya, R.P.3
Lim, W.A.4
-
19
-
-
1542465044
-
Organization and functions of interacting domains for signaling by protein-protein interactions
-
re14 14625370
-
Buck E Iyengar R Organization and functions of interacting domains for signaling by protein-protein interactions. Sci STKE 2003 2003 re14 14625370
-
(2003)
Sci STKE
, vol.2003
-
-
Buck, E.1
Iyengar, R.2
-
20
-
-
37649028224
-
Finding and evaluating community structure in networks
-
10.1103/PhysRevE.69.026113 026113
-
Newman MEJ Girvan M Finding and evaluating community structure in networks. Phys Rev E 2004 69 026113 10.1103/PhysRevE.69.026113
-
(2004)
Phys Rev E
, vol.69
-
-
Newman, M.E.J.1
Girvan, M.2
-
21
-
-
0037062448
-
Community structure in social and biological networks
-
122977 12060727 10.1073/pnas.122653799
-
Girvan M Newman MEJ Community structure in social and biological networks. Proc Natl Acad Sci USA 2002 99 7821-7826 122977 12060727 10.1073/pnas.122653799
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7821-7826
-
-
Girvan, M.1
Newman, M.E.J.2
-
22
-
-
25444490121
-
The use of edge-betweenness clustering to investigate biological function in protein interaction networks
-
555937 15740614 10.1186/1471-2105-6-39
-
Dunn R Dudbridge F Sanderson CM The use of edge-betweenness clustering to investigate biological function in protein interaction networks. BMC Bioinformatics 2005 6 39 555937 15740614 10.1186/1471-2105-6-39
-
(2005)
BMC Bioinformatics
, vol.6
, pp. 39
-
-
Dunn, R.1
Dudbridge, F.2
Sanderson, C.M.3
-
23
-
-
0037345719
-
Subnetwork hierarchies of biochemical pathways
-
10.1093/bioinformatics/btg033 12611809
-
Holme P Huss M Jeong H Subnetwork hierarchies of biochemical pathways. Bioinformatics 2003 19 532-538 10.1093/bioinformatics/btg033 12611809
-
(2003)
Bioinformatics
, vol.19
, pp. 532-538
-
-
Holme, P.1
Huss, M.2
Jeong, H.3
-
24
-
-
2942564706
-
Detecting community structure in networks
-
10.1140/epjb/e2004-00124-y
-
Newman MEJ Detecting community structure in networks. Eur Phys J B 2004 38 321-330 10.1140/epjb/e2004-00124-y
-
(2004)
Eur Phys J B
, vol.38
, pp. 321-330
-
-
Newman, M.E.J.1
-
25
-
-
25444448797
-
Spontaneous evolution of modularity and network motifs
-
1236541 16174729 10.1073/pnas.0503610102
-
Kashtan N Alon U Spontaneous evolution of modularity and network motifs. Proc Natl Acad Sci USA 2005 102 13773-13778 1236541 16174729 10.1073/ pnas.0503610102
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13773-13778
-
-
Kashtan, N.1
Alon, U.2
-
26
-
-
0035824662
-
The signal transfer regions of Gαs
-
10.1074/jbc.M107191200 11579096
-
Chen Y Yoo B Lee JB Weng G Iyengar R The signal transfer regions of Gαs. J Biol Chem 2001 276 45751-45754 10.1074/jbc.M107191200 11579096
-
(2001)
J Biol Chem
, vol.276
, pp. 45751-45754
-
-
Chen, Y.1
Yoo, B.2
Lee, J.B.3
Weng, G.4
Iyengar, R.5
-
27
-
-
0036323612
-
Kinetic and allosteric consequences of mutations in the subunit and domain interfaces and the allosteric site of yeast pyruvate kinase
-
10.1006/abbi.2001.2634 11747307
-
Fenton AW Blair JB Kinetic and allosteric consequences of mutations in the subunit and domain interfaces and the allosteric site of yeast pyruvate kinase. Arch Biochem Biophys 2002 397 28-39 10.1006/ abbi.2001.2634 11747307
-
(2002)
Arch Biochem Biophys
, vol.397
, pp. 28-39
-
-
Fenton, A.W.1
Blair, J.B.2
-
28
-
-
3543017313
-
Allosteric inhibition of protein tyrosine phosphatase 1B
-
10.1038/nsmb803 15258570
-
Wiesmann C Barr KJ Kung J Zhu J Erlanson DA Shen W Fahr BJ Zhong M Taylor L Randal M et al Allosteric inhibition of protein tyrosine phosphatase 1B. Nat Struct Mol Biol 2004 11 730-737 10.1038/nsmb803 15258570
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 730-737
-
-
Wiesmann, C.1
Barr, K.J.2
Kung, J.3
Zhu, J.4
Erlanson, D.A.5
Shen, W.6
Fahr, B.J.7
Zhong, M.8
Taylor, L.9
Randal, M.10
-
29
-
-
0030753197
-
Identification of common and distinct residues involved in the interaction of αi2 and αs with adenylyl cyclase
-
10.1074/jbc.272.33.20619 9252377
-
Grishina G Berlot CH Identification of common and distinct residues involved in the interaction of αi2 and αs with adenylyl cyclase. J Biol Chem 1997 272 20619-20626 10.1074/jbc.272.33.20619 9252377
-
(1997)
J Biol Chem
, vol.272
, pp. 20619-20626
-
-
Grishina, G.1
Berlot, C.H.2
-
30
-
-
2542623028
-
An electrostatic driven conformational transition is involved in the mechanism of substrate binding in cytochrome P450eryF
-
10.1021/bi036260l 15157081
-
Davydov DR Botchkareva AE Kumar S He YQ Halpert JR An electrostatic driven conformational transition is involved in the mechanism of substrate binding in cytochrome P450eryF. Biochemistry 2004 43 6475-6485 10.1021/bi036260l 15157081
-
(2004)
Biochemistry
, vol.43
, pp. 6475-6485
-
-
Davydov, D.R.1
Botchkareva, A.E.2
Kumar, S.3
He, Y.Q.4
Halpert, J.R.5
-
31
-
-
0035998284
-
Site-directed mutagenesis of cytochrome P450eryF: Implications for substrate oxidation, cooperativity, and topology of the active site
-
10.1021/tx025539k 12067252
-
Khan KK He YA He YQ Halpert JR Site-directed mutagenesis of cytochrome P450eryF: Implications for substrate oxidation, cooperativity, and topology of the active site. Chem Res Toxicol 2002 15 843-853 10.1021/ tx025539k 12067252
-
(2002)
Chem Res Toxicol
, vol.15
, pp. 843-853
-
-
Khan, K.K.1
He, Y.A.2
He, Y.Q.3
Halpert, J.R.4
-
32
-
-
0034724310
-
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity
-
16190 10716705 10.1073/pnas.050406897
-
5Cupp-Vickery J Anderson R Hatziris Z Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity. Proc Natl Acad Sci USA 2000 97 3050-3055 16190 10716705 10.1073/pnas.050406897
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3050-3055
-
-
Cupp-Vickery, J.1
Anderson, R.2
Hatziris, Z.3
-
33
-
-
33846383667
-
Differential behavior of the sub-sites of cytochrome 450 active site in binding of substrates, and products (implications for coupling/ uncoupling)
-
Narasimhulu S Differential behavior of the sub-sites of cytochrome 450 active site in binding of substrates, and products (implications for coupling/uncoupling). Biochim Biophys Acta 2007 1770 360-375 17134838
-
(2007)
Biochim Biophys Acta
, vol.1770
, pp. 360-375
-
-
Narasimhulu, S.1
-
34
-
-
46049099517
-
-
National Center for Biotechnology Information http://www.ncbi.nlm.nih.gov
-
-
-
-
36
-
-
46049087071
-
-
CATH Protein Structure Classification Database http://www.cathdb.info/ latest/index.html
-
-
-
-
37
-
-
0242720597
-
Uncovering network systems within protein structures
-
10.1016/j.jmb.2003.08.061 14636602
-
Green L Higman V Uncovering network systems within protein structures. J Mol Biol 2003 334 781-791 10.1016/j.jmb.2003.08.061 14636602
-
(2003)
J Mol Biol
, vol.334
, pp. 781-791
-
-
Green, L.1
Higman, V.2
-
38
-
-
0032530836
-
A database of macromolecular motions
-
147832 9722650 10.1093/nar/26.18.4280
-
Gerstein M Krebs W A database of macromolecular motions. Nucleic Acids Res 1998 26 4280-4290 147832 9722650 10.1093/nar/26.18.4280
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 4280-4290
-
-
Gerstein, M.1
Krebs, W.2
-
39
-
-
46049116183
-
-
Database of Macromolecular Movements http://molmovdb.org
-
-
-
-
40
-
-
0036721233
-
Normal mode analysis of macromolecular motions in a database framework: Developing mode concentration as a useful classifying statistic
-
10.1002/prot.10168 12211036
-
Krebs WG Alexandrov V Wilson CA Echols N Yu H Gerstein M Normal mode analysis of macromolecular motions in a database framework: Developing mode concentration as a useful classifying statistic. Proteins 2002 48 682-695 10.1002/prot.10168 12211036
-
(2002)
Proteins
, vol.48
, pp. 682-695
-
-
Krebs, W.G.1
Alexandrov, V.2
Wilson, C.A.3
Echols, N.4
Yu, H.5
Gerstein, M.6
-
41
-
-
13444254300
-
PDBsum more: New summaries and analyses of the known 3D structures of proteins and nucleic acids
-
539955 15608193 10.1093/nar/gki001
-
Laskowski RA Chistyakov VV Thornton JM PDBsum more: New summaries and analyses of the known 3D structures of proteins and nucleic acids. Nucleic Acids Res 2005 33 D266-D268 539955 15608193 10.1093/nar/gki001
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Laskowski, R.A.1
Chistyakov, V.V.2
Thornton, J.M.3
-
42
-
-
46049091686
-
-
PDBsum Database http://www.ebi.ac.uk/thornton-srv/databases/pdbsum/
-
-
-
-
43
-
-
46049108664
-
-
Accelrys DS Viewer Pro http://www.accelrys.com/dstudio/ds_viewer/ index.html
-
-
-
-
44
-
-
38049036713
-
A parallel edge-betweenness clustering tool for protein interaction networks
-
10.1504/IJDMB.2007.011611
-
Yang Q Lonardi S A parallel edge-betweenness clustering tool for protein interaction networks. Int J Data Mining Bioinformatics 2007 1 241-247 10.1504/IJDMB.2007.011611
-
(2007)
Int J Data Mining Bioinformatics
, vol.1
, pp. 241-247
-
-
Yang, Q.1
Lonardi, S.2
-
45
-
-
14644396645
-
Functional cartography of complex metabolic networks
-
10.1038/nature03288 15729348
-
Guimerà R Nunes Amaral LA Functional cartography of complex metabolic networks. Nature 2005 433 895-900 10.1038/nature03288 15729348
-
(2005)
Nature
, vol.433
, pp. 895-900
-
-
Guimerà, R.1
Nunes Amaral, L.A.2
-
46
-
-
2442456104
-
A method for simultaneous alignment of multiple protein structures
-
10.1002/prot.10628 15162494
-
Shatsky M Nussinov R Wolfson HJ A method for simultaneous alignment of multiple protein structures. Proteins 2004 56 143-56 10.1002/prot.10628 15162494
-
(2004)
Proteins
, vol.56
, pp. 143-156
-
-
Shatsky, M.1
Nussinov, R.2
Wolfson, H.J.3
-
47
-
-
46049108861
-
-
MultiProt http://bioinfo3d.cs.tau.ac.il/MultiProt
-
-
-
-
48
-
-
0030000410
-
Crystal structure of T state haemoglobin with oxygen bound at all four haems
-
10.1006/jmbi.1996.0124 8642597
-
Paoli M Liddington R Tame J Wilkinson A Dodson G Crystal structure of T state haemoglobin with oxygen bound at all four haems. J Mol Biol 1996 256 775-792 10.1006/jmbi.1996.0124 8642597
-
(1996)
J Mol Biol
, vol.256
, pp. 775-792
-
-
Paoli, M.1
Liddington, R.2
Tame, J.3
Wilkinson, A.4
Dodson, G.5
-
49
-
-
0031859481
-
The stereochemical mechanism of the cooperative effects in hemoglobin revisited
-
10.1146/annurev.biophys.27.1.1 9646860
-
Perutz MF Wilkinson AJ Paoli M Dodson GG The stereochemical mechanism of the cooperative effects in hemoglobin revisited. Annu Rev Biophys Biomol Struct 1998 27 1-34 10.1146/annurev.biophys.27.1.1 9646860
-
(1998)
Annu Rev Biophys Biomol Struct
, vol.27
, pp. 1-34
-
-
Perutz, M.F.1
Wilkinson, A.J.2
Paoli, M.3
Dodson, G.G.4
-
50
-
-
0026562948
-
Glycogen phosphorylase: Control by phosphorylation and allosteric effectors
-
1544539
-
Johnson LN Glycogen phosphorylase: Control by phosphorylation and allosteric effectors. FASEB J 1992 6 2274-82 1544539
-
(1992)
FASEB J
, vol.6
, pp. 2274-2282
-
-
Johnson, L.N.1
-
52
-
-
0034660681
-
A new allosteric site in glycogen phosphorylase B as a target for drug interactions
-
10.1016/S0969-2126(00)00144-1 10873856
-
Oikonomakos NG Skamnaki VT Tsitsanou KE Gavalas NG Johnson LN A new allosteric site in glycogen phosphorylase B as a target for drug interactions. Structure 2000 8 575-584 10.1016/S0969-2126(00)00144-1 10873856
-
(2000)
Structure
, vol.8
, pp. 575-584
-
-
Oikonomakos, N.G.1
Skamnaki, V.T.2
Tsitsanou, K.E.3
Gavalas, N.G.4
Johnson, L.N.5
-
53
-
-
0029953209
-
Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states
-
10.1021/bi960072w 8652510
-
Mitchell EP Withers G Ermert P Vasella AT Garman EF Oikonomakos NG Johnson LN Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states. Biochemistry 1996 35 7341- 7355 10.1021/bi960072w 8652510
-
(1996)
Biochemistry
, vol.35
, pp. 7341-7355
-
-
Mitchell, E.P.1
Withers, G.2
Ermert, P.3
Vasella, A.T.4
Garman, E.F.5
Oikonomakos, N.G.6
Johnson, L.N.7
-
54
-
-
1642304065
-
Structural determinants of allosteric ligand activation in RXR heterodimers
-
10.1016/S0092-8674(04)00119-9 15016376
-
Schulman AI Larson C Mangelsdorf DJ Ranganathan R Structural determinants of allosteric ligand activation in RXR heterodimers. Cell 2004 116 417-429 10.1016/S0092-8674(04)00119-9 15016376
-
(2004)
Cell
, vol.116
, pp. 417-429
-
-
Schulman, A.I.1
Larson, C.2
Mangelsdorf, D.J.3
Ranganathan, R.4
-
55
-
-
0033855471
-
Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix
-
316898 10.1101/gad.802300
-
Gampe RT Jr Montana VG Lambert MH Wisely B Milburn MV Xu HE Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix. Genes Dev 2000 14 2229-2241 316898 10970886 10.1101/ gad.802300
-
(2000)
Genes Dev
, vol.14
, pp. 2229-2241
-
-
Gampe Jr., R.T.1
Montana, V.G.2
Lambert, M.H.3
Wisely, B.4
Milburn, M.V.5
Xu, H.E.6
-
56
-
-
0033681001
-
Assymetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
-
10.1016/S1097-2765(00)80448-7 10882139
-
Gampe RT Jr Montana VG Lambert MH Miller AB Bledsoe RK Milburn MV Kliewer SA Willson TM Xu HE Assymetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors. Mol Cell 2000 5 545-555 10.1016/ S1097-2765(00)80448-7 10882139
-
(2000)
Mol Cell
, vol.5
, pp. 545-555
-
-
Gampe Jr., R.T.1
Montana, V.G.2
Lambert, M.H.3
Miller, A.B.4
Bledsoe, R.K.5
Milburn, M.V.6
Kliewer, S.A.7
Willson, T.M.8
Xu, H.E.9
-
57
-
-
0032698634
-
Transcription activation by catabolite activator protein (CAP)
-
10.1006/jmbi.1999.3161 10550204
-
Busby S Ebright RH Transcription activation by catabolite activator protein (CAP). J Mol Biol 1999 293 199-213 10.1006/jmbi.1999.3161 10550204
-
(1999)
J Mol Biol
, vol.293
, pp. 199-213
-
-
Busby, S.1
Ebright, R.H.2
-
58
-
-
0034671172
-
Modeling the cAMP-induced allosteric transition using the crystal structure of CAP-cAMP at 2.1 A resolution
-
10.1006/jmbi.2000.4231 11124031
-
Passner JM Schultz SC Steitz TA Modeling the cAMP-induced allosteric transition using the crystal structure of CAP-cAMP at 2.1 A resolution. J Mol Biol 2000 304 847-859 10.1006/jmbi.2000.4231 11124031
-
(2000)
J Mol Biol
, vol.304
, pp. 847-859
-
-
Passner, J.M.1
Schultz, S.C.2
Steitz, T.A.3
-
59
-
-
0035810698
-
Allosteric regulation of the cAMP receptor protein
-
11343786
-
Harman JG Allosteric regulation of the cAMP receptor protein. Biochim Biophys Acta 2001 1547 1-17 11343786
-
(2001)
Biochim Biophys Acta
, vol.1547
, pp. 1-17
-
-
Harman, J.G.1
-
60
-
-
30744477964
-
Kinetic and structural studies of the allosteric conformational changes induced by binding of cAMP receptor protein from Escherichia coli
-
10.1021/bi051586a 16401068
-
Fic E Polit A Wasylewsky Z Kinetic and structural studies of the allosteric conformational changes induced by binding of cAMP receptor protein from Escherichia coli. Biochemistry 2006 45 373-380 10.1021/ bi051586a 16401068
-
(2006)
Biochemistry
, vol.45
, pp. 373-380
-
-
Fic, E.1
Polit, A.2
Wasylewsky, Z.3
-
61
-
-
0000445736
-
The structure of a CAP-DNA complex having two cAMP molecules bound to each monomer
-
20284 9096308 10.1073/pnas.94.7.2843
-
Passner JM Steitz TA The structure of a CAP-DNA complex having two cAMP molecules bound to each monomer. Proc Natl Acad Sci USA 1997 94 2843-2847 20284 9096308 10.1073/pnas.94.7.2843
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2843-2847
-
-
Passner, J.M.1
Steitz, T.A.2
-
62
-
-
0035937256
-
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation
-
10.1006/jmbi.2001.4499 11254391
-
Smith TJ Peterson PE Schmidt T Fang J Stanley CA Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation. J Mol Biol 2001 307 707-720 10.1006/jmbi.2001.4499 11254391
-
(2001)
J Mol Biol
, vol.307
, pp. 707-720
-
-
Smith, T.J.1
Peterson, P.E.2
Schmidt, T.3
Fang, J.4
Stanley, C.A.5
-
63
-
-
0036304611
-
The structure of Apo human glutamate dehydrogenase details subunit communication and allostery
-
10.1016/S0022-2836(02)00161-4 12054821
-
Smith TJ Schmidt T Fang J Wu J Siuzdak G Stanley CA The structure of Apo human glutamate dehydrogenase details subunit communication and allostery. J Mol Biol 2002 318 765-777 10.1016/S0022-2836(02)00161-4 12054821
-
(2002)
J Mol Biol
, vol.318
, pp. 765-777
-
-
Smith, T.J.1
Schmidt, T.2
Fang, J.3
Wu, J.4
Siuzdak, G.5
Stanley, C.A.6
-
64
-
-
0033565447
-
The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery
-
10.1016/S0969-2126(99)80101-4 10425679
-
Peterson EP Smith TJ The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery. Structure 1999 7 769-782 10.1016/S0969-2126(99)80101-4 10425679
-
(1999)
Structure
, vol.7
, pp. 769-782
-
-
Peterson, E.P.1
Smith, T.J.2
-
65
-
-
1542379652
-
Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions
-
10.1074/jbc.M312671200 14660595
-
Madabushi S Gross AK Philippi A Meng EC Wensel TG Lichtarge O Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions. J Biol Chem 2004 279 8126-8132 10.1074/jbc.M312671200 14660595
-
(2004)
J Biol Chem
, vol.279
, pp. 8126-8132
-
-
Madabushi, S.1
Gross, A.K.2
Philippi, A.3
Meng, E.C.4
Wensel, T.G.5
Lichtarge, O.6
-
66
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
10.1126/science.289.5480.739 10926528
-
Palczewski K Kumasaka T Hori T Behnke CA Motoshima H Fox BA Trong IL Teller DC Okada T Stenkamp RE et al Crystal structure of rhodopsin: A G protein-coupled receptor. Science 2000 289 739-745 10.1126/ science.289.5480.739 10926528
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Trong, I.L.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
-
67
-
-
0030975286
-
Transducin-α C-terminal peptide binding site consists of C-D and E-F loops of rhodopsin
-
10.1074/jbc.272.10.6519 9045677
-
Acharya S Saad Y Karnik SS Transducin-α C-terminal peptide binding site consists of C-D and E-F loops of rhodopsin. J Biol Chem 1997 272 6519-6524 10.1074/jbc.272.10.6519 9045677
-
(1997)
J Biol Chem
, vol.272
, pp. 6519-6524
-
-
Acharya, S.1
Saad, Y.2
Karnik, S.S.3
-
68
-
-
0034948696
-
Structural mimicry in G protein-coupled receptors: Implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors
-
11408595
-
Ballesteros JA Shi L Javitch JA Structural mimicry in G protein-coupled receptors: Implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors. Mol Pharmacol 2001 60 1-19 11408595
-
(2001)
Mol Pharmacol
, vol.60
, pp. 1-19
-
-
Ballesteros, J.A.1
Shi, L.2
Javitch, J.A.3
-
69
-
-
0037457906
-
Evidence for structural changes in carboxyl-terminal peptides of transducin α-subunit upon binding a soluble mimic of light-activated rhodopsin
-
10.1021/bi0268899 12525157
-
Brabazon DM Abdulaev NG Marino JP Ridge KD Evidence for structural changes in carboxyl-terminal peptides of transducin α-subunit upon binding a soluble mimic of light-activated rhodopsin. Biochemistry 2003 42 302-311 10.1021/bi0268899 12525157
-
(2003)
Biochemistry
, vol.42
, pp. 302-311
-
-
Brabazon, D.M.1
Abdulaev, N.G.2
Marino, J.P.3
Ridge, K.D.4
-
70
-
-
18544366712
-
Structure and function of human erythrocyte pyruvate kinase
-
10.1074/jbc.M202107200 11960989
-
Valentini G Chiarelli LR Fortin R Dolzan M Galizzi A Abraham DJ Wang Ch Bianchi P Zanella A Mattevi A Structure and function of human erythrocyte pyruvate kinase. J Biol Chem 2002 277 23807-23814 10.1074/ jbc.M202107200 11960989
-
(2002)
J Biol Chem
, vol.277
, pp. 23807-23814
-
-
Valentini, G.1
Chiarelli, L.R.2
Fortin, R.3
Dolzan, M.4
Galizzi, A.5
Abraham, D.J.6
Wang, Ch.7
Bianchi, P.8
Zanella, A.9
Mattevi, A.10
-
71
-
-
0038241711
-
Pyruvate kinase: Current status of regulatory and functional properties
-
10.1016/S1096-4959(03)00081-2 12798932
-
Muñoz ME Ponce E Pyruvate kinase: Current status of regulatory and functional properties. Comp Biochem Physiol B Biochem Mol Biol 2003 135 197-218 10.1016/S1096-4959(03)00081-2 12798932
-
(2003)
Comp Biochem Physiol B Biochem Mol Biol
, vol.135
, pp. 197-218
-
-
Muñoz, M.E.1
Ponce, E.2
-
72
-
-
0038687151
-
Identification of substrate contact residues important for the allosteric regulation of phosphofructokinase from Escherichia coli
-
10.1021/bi034273t 12767227
-
Fenton AW Paricharttanakul NM Reinhart GD Identification of substrate contact residues important for the allosteric regulation of phosphofructokinase from Escherichia coli. Biochemistry 2003 42 6453-6459 10.1021/bi034273t 12767227
-
(2003)
Biochemistry
, vol.42
, pp. 6453-6459
-
-
Fenton, A.W.1
Paricharttanakul, N.M.2
Reinhart, G.D.3
-
73
-
-
8344286415
-
Disentangling the web of allosteric communication in a homotetramer: Heterotropic activation in phosphofructokinase from Escherichia coli
-
10.1021/bi048569q 15518560
-
Fenton AW Paricharttanakul NM Reinhart GD Disentangling the web of allosteric communication in a homotetramer: Heterotropic activation in phosphofructokinase from Escherichia coli. Biochemistry 2004 43 14104-14110 10.1021/bi048569q 15518560
-
(2004)
Biochemistry
, vol.43
, pp. 14104-14110
-
-
Fenton, A.W.1
Paricharttanakul, N.M.2
Reinhart, G.D.3
-
74
-
-
0024418704
-
Dissection of the effector-binding site and complementation studies of Escherichia coli phosphofructokinase using site-directed mutagenesis
-
10.1021/bi00443a010 2531002
-
Lau FT Fersht AR Dissection of the effector-binding site and complementation studies of Escherichia coli phosphofructokinase using site-directed mutagenesis. Biochemistry 1989 28 6841-6847 10.1021/ bi00443a010 2531002
-
(1989)
Biochemistry
, vol.28
, pp. 6841-6847
-
-
Lau, F.T.1
Fersht, A.R.2
-
75
-
-
0028133496
-
Converting trypsin to chymotrypsin: Residue 172 is a substrate specificity determinant
-
10.1021/bi00195a017 8038165
-
Hedstrom L Perona JJ Rutter WJ Converting trypsin to chymotrypsin: residue 172 is a substrate specificity determinant. Biochemistry 1994 33 8757-8763 10.1021/bi00195a017 8038165
-
(1994)
Biochemistry
, vol.33
, pp. 8757-8763
-
-
Hedstrom, L.1
Perona, J.J.2
Rutter, W.J.3
-
76
-
-
0031813817
-
Converting trypsin to elastase: Substitution of the S1 site and adjacent loops reconstitutes esterase specificity but not amidase activity
-
10.1093/protein/11.8.669 9749919
-
Hung SH Hedstrom L Converting trypsin to elastase: Substitution of the S1 site and adjacent loops reconstitutes esterase specificity but not amidase activity. Protein Eng 1998 11 669-673 10.1093/protein/11.8.669 9749919
-
(1998)
Protein Eng
, vol.11
, pp. 669-673
-
-
Hung, S.H.1
Hedstrom, L.2
-
77
-
-
0042622558
-
Three dimensional structures of S189D chymotrypsin and D189S trypsin mutants: The effect of polarity at site 189 on a protease-specific stabilization of the substrate-binding site
-
10.1016/S0022-2836(03)00849-0 12927546
-
Szabo E Venekei I Bocskei Z Naray-Szabo G Graf L Three dimensional structures of S189D chymotrypsin and D189S trypsin mutants: The effect of polarity at site 189 on a protease-specific stabilization of the substrate-binding site. J Mol Biol 2003 331 1121-1130 10.1016/ S0022-2836(03)00849-0 12927546
-
(2003)
J Mol Biol
, vol.331
, pp. 1121-1130
-
-
Szabo, E.1
Venekei, I.2
Bocskei, Z.3
Naray-Szabo, G.4
Graf, L.5
-
78
-
-
0033168389
-
The three-dimensional structure of Asp189Ser trypsin provides evidence for an inherent structural plasticity of the protease
-
10.1046/j.1432-1327.1999.00452.x 10429182
-
Szabo E Bocskei Z Naray-Szabo G Graf L The three-dimensional structure of Asp189Ser trypsin provides evidence for an inherent structural plasticity of the protease. Eur J Biochem 1999 263 20-26 10.1046/ j.1432-1327.1999.00452.x 10429182
-
(1999)
Eur J Biochem
, vol.263
, pp. 20-26
-
-
Szabo, E.1
Bocskei, Z.2
Naray-Szabo, G.3
Graf, L.4
-
79
-
-
0035929597
-
Modular design of Gβ as the basis for reversible specificity in effector stimulation
-
10.1074/jbc.M103228200 11457830
-
Buck E Iyengar R Modular design of Gβ as the basis for reversible specificity in effector stimulation. J Biol Chem 2001 276 36014-36019 10.1074/jbc.M103228200 11457830
-
(2001)
J Biol Chem
, vol.276
, pp. 36014-36019
-
-
Buck, E.1
Iyengar, R.2
|